Product Information: Similac Special Care 24 High Protein

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Product Information: Similac Special Care 24 High Protein 1 of 5

A 24 Cal/fl oz iron-fortified feeding for growing, low-birth-weight infants and premature infants who may need extra protein to help support growth. Use under medical supervision. OptiGRO is our exclusive blend of DHA, lutein and vitamin E: these important ingredients are found in breast milk. DHA for brain and eye development. Lutein to support eye health. Vitamin E, an important nutrient found in breast milk to support developing cells. 3.3 g of protein/100 Cal, 10% more protein than Similac Special Care 24. Designed as a liquid option to meet the higher protein needs of very-low-birth-weight preterm infants. When fed at 120 Cal/kg/day, meets the recommended 4 g protein/kg/day for very-lowbirth-weight infants. 1,2,3,4 Lutein, a carotenoid naturally found in colostrum and human milk, has been shown to help support eye health in the the preterm infant. 5,6,7,8 Calcium: phosphorus content and ratio (1.8:1) supports intrauterine accretion rates. 9 Approximately 2 mg iron/kg body weight per day when fed at 120 Cal/kg body weight per day. Gluten-free. Halal. Kosher. Safety Precautions Very-low-birthweight infants are particularly susceptible to gastrointestinal complications; therefore, feeding should be initiated cautiously. Tolerance to enteral feedings should be confirmed by initially offering small volumes of formula followed by cautious progression to higher caloric feedings. Spitting up, abdominal distension, abnormal stools or stool patterns, excessive gastric residuals, or other signs of intestinal dysfunction have been associated with enteral feeding before the intestinal tract is ready to accommodate the regimen. At first signs of these problems, enteral feeding should be slowed or discontinued. Not intended for feeding low-birth-weight infants after they reach a weight of 3600 g (approximately 8 lb) or as directed by a physician. Never use a microwave oven to warm formula. Serious burns can result. 1 Ziegler EE. J Pediatr Gastroenterol Nutr 2007;45:170-174. 2 Klein CJ. J Nutr 2002;132:1395S-1577S. 3 Kleinman RE, Greer FR (eds): Pediatric Nutrition, 7th ed. Elk Grove Village, IL: American Academy of Pediatrics: 2014:93. 4 Canadian Pediatric Society. CMAJ 1995;152(11):1765-1785. 5 Canfield LM, et al. Eur J Nutr 2003;42:133-141. 6 Schweigert FJ, et al. Eur J Nutr 2004;43:39-44. 7 Patton S, et al. Lipids 1990;25:159-165. 8 Rubin LP, et al. J Perinatol 2012;32:418-424. 9 Mize et al. Am J Clin Nutr 1995;62:385-391. Ingredients 2 of 5

Liquid Unflavored: Water, Nonfat Milk, Corn Syrup Solids, Medium-Chain Triglycerides, Whey Protein Concentrate, Lactose, Soy Oil, Coconut Oil. Less than 0.5% of: C. Cohnii Oil, M. Alpina Oil, Beta-Carotene, Lutein, Calcium Phosphate, Ascorbic Acid, Potassium Citrate, Calcium Carbonate, Soy Lecithin, Monoglycerides, Magnesium Chloride, m-inositol, Sodium Citrate, Carrageenan, Potassium Hydroxide, Ferrous Sulfate, Choline Bitartrate, Taurine, Choline Chloride, Niacinamide, L-Carnitine, Zinc Sulfate, Potassium Chloride, Salt, Potassium Phosphate, d-alpha-tocopheryl Acetate, Calcium Pantothenate, Vitamin A Palmitate, Cupric Sulfate, Riboflavin, Thiamine Chloride Hydrochloride, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Biotin, Phylloquinone, Sodium Selenate, Vitamin D3, Cyanocobalamin, and Nucleotides (Cytidine 5 -Monophosphate, Disodium Guanosine 5 -Monophosphate, Disodium Uridine 5 - Monophosphate, Adenosine 5 -Monophosphate). Allergens: Contains milk and soy ingredients. Availability List Number Item 56271 Similac Special Care 24 High Protein Ready to Feed / 2-fl-oz (59-mL) bottle / 48 ct 3 of 5

Nutrition Information - Liquid Unflavored 100 Cal (4.2 fl oz) 1000 ml (1.1 QT) Value %RDI / %DV Value %RDI / %DV Calories 100 812 Volume, ml 124 1000 Protein, g 3.3 26.8 Fat, g 5.43 44.07 Carbohydrate, g 10.0 81 Water, g 109 885 Linoleic Acid, mg 700 5681 Vitamin A, IU 1250 10144 Vitamin D, IU 150 1217 Vitamin E, IU 4.0 32.5 Vitamin K, mcg 12 97.4 Thiamin (Vitamin B1), mcg 250 2029 Riboflavin (Vitamin B2), mcg 620 5032 Vitamin B6, mcg 250 2029 Vitamin B12, mcg 0.55 4.46 Niacin, mcg 5000 40578 Folic Acid (Folacin), mcg 37 300 Pantothenic Acid, mcg 1900 15419 Biotin, mcg 37 300 Vitamin C (Ascorbic Acid), mg 37 300 Choline, mg 10 81 Inositol, mg 40 325 Calcium, mg 180 1461 Calcium, meq 9.0 72.9 Phosphorus, mg 100 812 Magnesium, mg 12 97.4 Iron, mg 1.8 14.6 Zinc, mg 1.5 12.17 Manganese, mcg 12 97 Copper, mcg 250 2029 Iodine, mcg 6 49 Selenium, mcg 2 16 Sodium, mg 43 349 Sodium, meq 1.9 15.2 Potassium, mg 129 1047 Potassium, meq 3.3 26.8 Chloride, mg 81 657 Chloride, meq 2.3 18.6 Potential Renal Solute Load, mosm 29.5 240 4 of 5

Preparation Can be mixed to a variety of caloric densities using the Liqui-Mix System. Follow physician's instructions. Instructions for Use: The health of the infant depends on carefully following the directions for preparation and use. Proper hygiene, handling and storage are important when preparing infant formula. Do not add water. Shake very well. Do not use if breakaway ring is missing or broken. Twist off cap. Twist on nipple and ring. Pour desired amount into feeding container (Volu-Feed or syringe) or attach clean, single-use nipple and ring (not included). Use sterile nipple and ring if directed. Once oral feeding begins, use within one hour or discard. If signs of intolerance develop, slow feeding or discontinue. Can be mixed to a variety of caloric densities using the Liqui-Mix System. Follow physician's instructions. Storage & Handling Instructions for Storage: Avoid prolonged exposure of bottles to light. Store unopened at room temperature; avoid extreme temperatures. For mixing: pour, recap, refrigerate and use within 24 hours. Do not reuse bottle. 5 of 5