Building a european consensus on minimum quality standards for drug treatment, rehabilitation and harm reduction

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Zurich Open Repository and Archive University of Zurich Main Library Strickhofstrasse 39 CH-8057 Zurich www.zora.uzh.ch Year: 2013 Building a european consensus on minimum quality standards for drug treatment, rehabilitation and harm reduction Schaub, Michael P; Uchtenhagen, Ambros DOI: https://doi.org/10.1159/000350740 Posted at the Zurich Open Repository and Archive, University of Zurich ZORA URL: https://doi.org/10.5167/uzh-84281 Accepted Version Originally published at: Schaub, Michael P; Uchtenhagen, Ambros (2013). Building a european consensus on minimum quality standards for drug treatment, rehabilitation and harm reduction. European Addiction Research, 19(6):314-324. DOI: https://doi.org/10.1159/000350740

Table 1: Sources of relevant documents: regional distribution Treatment/rehabilitation South-West Central-East North Lit. review 41 (20.1) 23 (13.7) 20 (20.2) Exp. opinion 40 (19.6) 43 (25.6) 23 (23.2) Exp. consensus 61 (29.9) 51 (30.4) 25 (25.3) Research project 22 (10.8) 15 (8.9) 12 (12.1) Practice experience 40 (19.6) 36 (21.4) 19 (19.2) Total: 204 (100.0) 168 (100.0) 99 (100.0) Harm reduction: Lit. review 7 (18.9) 8 (20.5) 7 (21.2) Exp. opinion 9 (24.3) 7 (17.9) 6 (18.2) Exp. consensus 8 (21.6) 13 (33.3) 6 (18.2) Research project 3 (8.1) 7 (17.9) 7 (21.2) Practice experience 10 (27.0) 4 (10.3) 7 (21.2) Total: 37 (100.0) 39 (100.0) 33 (100.0) Note: South-West includes Austria, Belgium, Cyprus, France, Germany, Greece, Italy, the Netherlands, Portugal, Spain, and Switzerland; Central-East includes Bulgaria, the Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Romania, Slovakia, Slovenia; North includes Denmark, Finland, Ireland, Sweden, and the United Kingdom 1 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

Table 2: Treatment and rehabilitation standards: number of documents, evidence grading, source of evidence, and level of obligation. Draft number, group, description, and explanation of quality Num- Number of documents / Source of document Level of standard ber of evidence grade obligation docu- A B C D E Lit. Exp. Exp. Re- Prac- Man- Re- ments re- opi- con- search tice da- co- view nion sen- pro- exper tory men- sus ject ience ded Structural standards of services TR1 Accessibility: location (service can easily be reached by public 57 0 0 1 4 6 22 28 31 14 26 51 6 transport) TR2 Physical environment: space (e.g., service has separate rooms 58 0 1 0 5 4 19 32 39 6 32 35 29 for individual counselling) TR3 Physical environment: safety (service is equipped for 67 0 1 3 3 4 28 29 45 12 40 42 21 reanimation and other emergencies, e.g., management of overdose) TR4 Indication criteria: diagnosis (treatment indication is always 101 5 1 8 4 11 49 58 74 22 54 53 69 made on the basis of a diagnosis) TR5 Staff composition: education (e.g., at least half of staff has a 104 1 0 3 4 14 44 62 76 25 60 52 57 diploma in medicine, nursing, social work, or psychology) TR6 Staff composition: transdisciplinarity (e.g., service employs a 105 0 1 3 2 11 38 52 63 19 51 68 42 2 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

multidisciplinary team composed of at least 3 professions) Process standards at the service level and of interventions TR7 Assessment procedures: substance use history, diagnosis and 166 13 3 21 36 37 78 89 105 40 78 104 62 treatment history have to be assessed TR8 Assessment procedures: somatic status and social status have to 138 5 2 9 21 30 65 78 89 39 63 91 47 be assessed TR9 Assessment procedures: psychiatric status has to be assessed 130 2 2 8 11 15 63 74 85 36 64 91 40 TR10 Individualised treatment planning (treatment plans are tailored 177 4 6 7 15 15 83 98 116 46 86 117 65 individually to the needs of the patient) TR11 Informed consent (patients must receive information on 140 3 1 7 12 3 68 80 93 36 71 68 77 available treatment options and agree with a proposed regime or plan before starting treatment) TR12 Written client records (assessment results, intervention plan, 141 1 0 8 4 6 65 75 92 32 68 70 76 interventions, expected changes and unexpected events are documented complete and up to date for each patient in a patient record) TR13 Confidentiality of client data (patient records are confidential 124 2 1 5 10 3 60 75 83 34 64 58 71 and exclusively accessible to staff involved in a patient s treatment or regime) 3 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

TR14 Routine cooperation with other agencies (whenever a service is 155 1 2 6 15 10 62 85 102 30 74 109 51 not equipped to address all needs of a given patient, another appropriate service is available for referral) TR15 Continued staff training (staff is regularly updated on relevant 111 3 0 3 12 8 55 74 86 31 64 77 39 new knowledge in their field of expertise) Outcome standards at the system level TR16 Goal: health stabilisation/improvement (treatment must be 138 2 0 9 5 4 66 77 93 31 58 110 30 aimed at improvement or stabilisation of health) TR17 Goal: social stabilisation/integration (treatment must be aimed 131 1 0 3 4 14 53 66 89 28 53 103 30 at improvement of social stabilisation or integration) TR18 Goal: reduced substance use (treatment must be aimed at a 147 4 2 9 5 8 62 78 93 37 65 98 40 reduction of substance use, e.g., helping the client/patient to reduce the use of or to abstain from psychotropic substances) TR19 Utilisation monitoring (services must periodically report the 57 0 2 2 4 0 18 33 37 15 29 37 20 occupancy of treatment slots or beds) TR20 Discharge monitoring (e.g., ratio of regular / irregular 48 0 0 1 3 0 13 31 33 10 26 33 20 discharges, retention rates, etc., have to be periodically monitored) TR21 Internal evaluation (services must regularly perform an internal 73 2 0 4 6 6 27 46 55 18 41 54 24 evaluation of their activities and outcomes) 4 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

TR22 External evaluation (services must regularly allow an 56 0 0 2 7 0 18 36 39 14 32 37 24 evaluation of their activities and outcomes by an independent external evaluator) TR23 Cost-effectiveness ratio (positive outcomes, e.g., number of 16 6 2 2 1 0 13 13 13 7 12 11 5 abstinent patients in relation to treatment costs) TR24 Cost-benefit ratio (tangible benefits, e.g., years of increased 2 1 0 0 0 0 2 2 2 2 2 1 1 life expectancy in relation to treatment costs) 5 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

Table 3: Harm reduction quality standards: number of documents, evidence grading, source of evidence, and level of obligation per standard. Draft number, group, description, and explanation of quality standard Number of documents Number of documents / evidence grade A B C D E Literature re- Source of Document Expert Expert Research opiniosen- con- pro- Practice experi Level of obligation Man- Redatorcomen- view sus ject ence ded Structural standards interventions HR1 Accessibility: costs not to be paid by clients (exclusion of costs 15 0 0 1 0 0 7 7 3 4 10 8 8 that limit the accessibility for poor clients/patients) HR2 Accessibility: location (service can easily be reached by public 33 0 0 2 2 1 11 10 8 11 17 23 10 transport) HR3 Accessibility: opening hours (adjusted to the needs of 26 0 0 2 2 2 12 12 9 7 13 19 7 clients/patients, e.g., evenings & weekends) HR4 Staff qualification: minimal qualification (e.g., at least half of 29 0 0 1 2 1 12 17 12 10 22 21 11 staff has a diploma in nursing, social work, or psychology) HR5 Staff composition: transdisciplinarity (e.g., service employs a 24 0 0 1 2 1 12 17 12 10 22 15 9 6 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

multidisciplinary team composed of at least 2 professions) HR6 Indication criteria: age limits (e.g., minimal age required for 23 0 0 0 5 3 9 13 11 3 11 19 7 admittance) HR7 Indication criteria: diagnosis (treatment indication is always 14 0 0 0 5 3 9 13 11 3 11 6 8 made on the basis of a diagnosis or, if not possible, a detailed assessment of the current substance use) Process standards interventions HR8 Assessment procedures: risk behaviour assessment 24 0 0 2 1 1 15 12 8 9 15 21 3 (client s/patient s risk behaviour is assessed) HR9 Assessment procedures: complete needs assessment and 26 0 0 2 3 2 9 11 9 8 13 18 8 prioritisation (e.g., 1. harm reduction of intravenous drug use and, 2. reduction of used syringes in public spaces, etc.) HR10 Assessment procedures: client/patient status (the client s health 30 0 0 2 5 3 16 17 14 10 16 28 2 status is assessed) HR11 Informed consent (clients/patients must receive information on 23 0 0 2 5 1 12 13 14 6 11 14 12 available service options and agree with a proposed regime or plan before starting an intervention) HR12 Confidentiality of client data (client/patient records are 36 0 0 3 6 1 18 17 17 10 19 19 20 confidential and exclusively accessible to staff involved in a client s/ 7 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

patient s intervention or regime) HR13 Written client records (assessment results, intervention plan, 18 0 0 2 0 0 12 11 7 7 13 16 2 interventions, expected changes and unexpected events are documented completely and updated for each client/patient in a client/patient record) HR14 Individualised treatment planning (intervention regime and 33 0 0 1 2 0 13 15 10 9 16 28 6 intervention plans, if applicable, are tailored individually to the needs of the client/patient) HR15 Routine cooperation with other agencies (whenever a service is 49 0 0 3 9 1 22 23 22 15 22 28 24 not equipped to address all needs of a given patient/client, another appropriate service is available for referral) HR16 Continued staff training (staff is regularly updated on relevant 30 1 0 2 3 0 17 18 15 8 20 24 9 new knowledge in their field of action) HR17 Neighbourhood/community consultation (avoiding nuisance 20 0 0 2 1 1 9 12 10 7 8 12 9 and conflict with other people around the service) Outcome standards at system level HR18 Goal: reduced risk behaviour (reducing unsafe injections, 62 2 0 4 7 1 25 25 25 15 26 43 22 unsafe drug use and unprotected sex) HR19 Goal: reduced substance use (treatment must be aimed at a 26 1 0 3 3 1 17 19 16 11 20 23 3 8 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

reduction of substance use, e.g., helping the client/patient to reduce the use of or to abstain from psychotropic substances) HR20 Goal: referrals (treatment services must be prepared to refer 44 1 0 3 3 1 17 19 16 11 20 33 12 patients to other health/social/treatment services if needed and agreed) HR21 Internal evaluation (services must regularly perform an internal 20 1 0 0 0 0 9 15 12 8 11 14 9 evaluation of their activities and outcomes) HR22 External evaluation (services must regularly allow an 21 1 0 1 1 0 11 17 13 9 11 14 10 evaluation of their activities and outcomes by an independent external evaluator) HR23 Utilisation monitoring (services must periodically report the 24 0 0 1 0 0 8 15 12 19 18 16 10 occupancy of service slots) HR24 Cost-effectiveness ratio (positive outcomes, e.g., number of 5 0 0 1 0 0 5 4 3 3 2 4 1 abstinent patients in relation to service costs) HR25 Cost-benefit ratio (tangible benefits, e.g., years of increased life 3 0 0 1 0 0 3 3 3 3 2 2 1 expectancy in relation to service costs) 9 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

Table 4: Treatment/rehabilitation: implementation status, feasibility in respective country, and overall personal acceptability of quality standards n Imple- Feasible Problems Not No Overall Excep- mented no expected feasible answer personal tions to problems at all accept- accept- ability ability 1) Structural standards services TR1 Accessibility: location (service can easily be reached by public transport) 153 21.6 30.1 38.6 3.9 5.9 85.0 3 TR2 TR3 TR4 TR5 TR6 Physical environment: adequate spacing for the activities in the service (e.g., service has separate rooms for individual counselling) Physical environment: safety (service is equipped for emergencies, e.g., management of overdose, fire or aggression on the premises) Indication criteria: diagnosis (treatment indication is always made on the basis of a diagnosis) Staff composition: basic education (e.g., at least half of staff has a diploma in medicine, nursing, social work, or psychology) Staff composition: transdisciplinarity (e.g., service employs a multidisciplinary team composed of at least 3 professions) 149 39.6 28.2 23.5 1.3 7.4 91.9 6 150 26.7 19.3 33.3 9.3 11.3 78.0 6 145 41.4 23.4 26.9 1.4 6.9 84.1 6, 4 142 47.9 23.9 16.9 6.3 4.9 90.1 6, 4, 3 143 25.9 21.0 41.3 7.7 4.2 79.7 6, 3 10 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

Process standards of services TRs7 TRs8 Assessment procedures: substance use history, diagnosis and treatment history have to be assessed Assessment procedures: somatic status and social status have to be assessed 84 44.0 38.1 11.9 1.2 4.8 92.9 6, 4 84 35.7 39.3 15.5 2.4 7.1 88.1 6, 4 TRs9 Assessment procedures: psychiatric status has to be assessed 84 23.8 32.1 32.1 3.6 8.3 77.4 6 TRs10 TRs11 TRs12 TRs13 TRs14 Individualised treatment planning (treatment plans are tailored individually to the needs of the patient) Informed consent (patients must receive information on available treatment options and agree with a proposed regime, plan or change of plan before starting treatment) Written client records (patient records, including assessment results, intervention plan, interventions, expected changes and unexpected events, are documented and up to date for each patient) Confidentiality of client data (patient records are confidential and exclusively accessible to staff involved in a patient s treatment or regime) Routine cooperation with other agencies (whenever a service is not equipped to deal with all needs of a given patient, an appropriate service 84 38.1 22.6 28.6 3.6 7.1 91.7 6, 3, 4 84 42.9 39.3 11.9 0.0 6.0 86.9 6, 3, 4 84 42.9 26.2 19.0 3.6 8.3 86.9 6 84 56.0 26.2 11.9 0.0 3.3 94.0 6 84 25.0 26.2 35.7 6.0 7.1 90.5 3, 6 11 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

TRs15 is available for referral) Continued staff training (staff is regularly updated on relevant new knowledge in their field of action) 84 29.8 23.8 40.5 0.0 6.0 92.9 6 Process standards of interventions TRi7 TRi8 Assessment procedures: substance use history, diagnosis and treatment history have to be assessed Assessment procedures: somatic status and social status have to be assessed 55 45.5 23.6 29.1 0.0 1.8 94.5-55 40.0 30.9 23.6 3.6 1.8 92.7 - TRi9 Assessment procedures: psychiatric status has to be assessed 55 30.9 23.6 36.4 7.3 1.8 74.5 4, 7, 1, 6 2) TRi10 TRi11 TRi12 Individualised treatment planning (treatment plans are tailored individually to the needs of the patient) Informed consent (patients must receive information on available treatment options and agree with a proposed regime, plan or change of plan before starting treatment) Written client records (patient records, including assessment results, intervention plan, interventions, expected changes and unexpected events, are documented complete and up to date for each patient) 55 40.0 12.7 41.8 1.8 3.6 90.9-55 40.0 25.5 29.1 3.6 1.8 89.1-55 36.4 23.6 38.2 0.0 1.8 85.5 - TRi13 Confidentiality of client data (patient records are confidential and 55 60.0 25.5 12.7 0.0 1.8 94.5-12 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

TRi14 TRi15 exclusively accessible to staff involved in a patient s treatment or regime) Routine cooperation with other agencies (whenever a service is not equipped to deal with all needs of a given patient, an appropriate service is available for referral) Continued staff training (staff is regularly updated on relevant new knowledge in their field of action) 55 29.1 18.2 49.1 1.8 1.8 92.7-55 30.9 16.4 45.5 5.5 1.8 92.7 - Outcome standards at system level TR16 TR17 TR18 TR19 TR20 Goal: health stabilisation/improvement (treatment must aim for improvement or stabilisation of health) Goal: social stabilisation/integration (treatment must aim for improvements in social stabilisation or integration) Goal: reduced substance use (treatment must aim for a reduction of substance use, e.g., helping the client/patient to reduce use or to abstain from illegal or non-prescribed psychotropic substances) Utilisation monitoring (services must periodically report the occupancy rate of treatment slots or beds) Discharge monitoring (e.g., ratio of regular/irregular discharges and retention rates have to be monitored periodically) 142 41.5 28.9 21.8 1.4 6.3 95.8 6 142 28.9 27.5 33.8 4.2 5.6 92.3 4, 6, 3 142 37.3 31.0 24.6 1.4 5.6 88.0 6, 4 142 30.3 30.3 28.9 2.8 7.7 87.3 6, 4 142 14.8 24.6 40.1 12.0 8.5 79.6 4, 6, 3 13 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

TR21 TR22 TR23 3) TR24 3) Internal evaluation (services must regularly perform an internal evaluation of their activities and outcomes) External evaluation (services must regularly allow an evaluation of their activities and outcomes by an independent external evaluator) Cost-effectiveness ratio (positive outcomes, e.g., number of abstinent patients in relation to treatment costs) Cost-benefit ratio (tangible benefits, e.g., years of increased life expectancy in relation to treatment costs) 142 23.2 24.6 38.7 8.5 4.9 85.9 4, 6, 3 141 7.8 15.6 53.2 17.0 6.4 78.7 4, 6, 3 140 3.6 11.4 51.4 22.1 11.4 65.7 6, 4, 3, 5, 1, 2 139 2.2 9.4 41.7 31.7 15.1 58.3 6, 4, 3, 5, 1, 2 1) 1 = out-patient services, 2 = in-patient services, 3 = prison-based services, 4 = office-based services, 5 = specialised teams, 6 = non-specialised teams. Note: exceptions are ordered from high to low relevance; 2) categories for process standards of interventions: 1 = counselling, 2 = psycho-social, 3 = substitution maintenance, 4 = heroin-assisted treatment, 5 = detoxification, 6 = vocational rehabilitation, 7 = other rehabilitation. Note: exceptions are ordered from high to low relevance; 3) these MQS were excluded from the list after the conference. 14 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

Table 5: Harm reduction: implementation status, feasibility in respective country, and overall personal acceptability of quality standards n Imple- Feasible Problems Not No Overall Excep- mented no expected feasible answer personal tions to problems at all accept- accept- ability ability 1) Structural standards of interventions HR1 Accessibility: costs to be paid by clients (exclusion of costs which limit accessibility for poor clients/patients) 138 23.2 18.1 26.1 21.7 10.9 46.4 4, 7, 8, 3, 9, 6, 5, 1, 2, 10 HR2 Accessibility: location (service can easily be reached by public transport) 147 17.0 23.1 44.9 10.2 4.8 87.1 4, 10, 5, 3 HR3 HR4 2) Accessibility: opening hours (adjusted to the needs of clients/patients, e.g., evenings & weekends) Staff qualification: minimal qualification (staff has to be qualified and the staff qualifications have to be made transparent, e.g., for two trained peers in the service, two have a diploma in social work and further two have 140 16.4 24.3 43.6 14.3 1.4 83.6 5, 6, 4, 7, 9, 10, 8 133 35.3 27.1 22.6 10.5 4.5 84.2 1, 10, 3, 9, 8 15 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

HR5 3) HR6 2) HR7 3) diplomas in in nursing) Staff composition: transdisciplinarity (e.g., service employs a multidisciplinary team composed of at least 2 professions) Indication criteria: age limits (1. Services have to be age appropriate and staff have to be trained to meet age appropriate clients needs, 2. There should be no age limits in harm reduction services) Indication criteria: diagnosis (treatment indication is always made on the basis of a diagnosis or, if not possible, a detailed assessment of current substance use) 133 17.3 19.5 33.8 24.1 5.3 64.7 4, 10, 6, 9, 1, 8, 3, 5, 7, 2 135 21.5 20.7 28.9 15.6 13.3 29.6-137 29.2 21.9 23.4 16.8 8.8 62.8 4, 3, 9, 8, 10, 1, 5, 6, 2, 7 Process standards of interventions HR8 HR9 HR10 Assessment procedures: risk behaviour assessment (client/patient risk behaviour is assessed) Assessment procedures: complete needs assessment and prioritisation (e.g. 1. harm reduction of intravenous drug use and, 2. reduction of used syringes in public spaces) Assessment procedures: client/patient status (the client/patient health status is assessed) 125 24.0 35.2 24.8 10.4 5.6 76.8 4, 10, 6, 5 127 14.2 31.5 28.3 13.4 12.6 74.8 4, 5, 10, 6, 7, 9, 3, 8 126 20.6 32.5 26.2 11.1 9.5 69.8 4, 3, 8, 9, 10, 5, 7 16 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

HR11 2) Informed consent (clients/patients must receive information on available service options and agree with a proposed regime or plan before starting an 124 39.5 28.2 20.2 7.3 4.8 84.7 4, 3, 1, 10, 8, 9 HR12 HR13 3) HR14 HR15 HR16 intervention. Interventions should not be based on written informed consent, but rather on transparent information regarding all the treatments offered by a service) Confidentiality of client data (client/patient records are confidential and exclusively accessible to staff involved in a client s/patient s intervention or regime) Written records (assessment results, intervention plan, interventions, expected changes and unexpected events are documented and up to date for each client/patient in a client/patient record) Individualised treatment planning (intervention regime and intervention plans, if applicable, are individually tailored to the needs of the client/patient) Routine cooperation with other agencies (whenever a service is not equipped to deal with all needs of a given client/patient, an appropriate service available for referral) Continued staff training (staff is regularly updated on relevant new knowledge in their field of action) 124 55.6 27.4 12.1 1.6 3.2 95.2 4 124 21.0 25.8 25.8 19.4 8.1 58.1 4, 1, 3, 9, 8, 2, 10, 5, 7, 6 125 20.0 25.6 32.8 16.8 4.8 73.6 4, 1, 3, 2, 8, 9, 5, 10, 6, 7 124 34.7 20.2 39.5 4.0 1.6 91.9 4 123 25.2 27.6 41.5 4.9 0.8 95.9 4 17 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

HR17 Neighbourhood/community consultation (avoiding nuisance and conflict with other people around the service) 123 22.8 22.8 32.5 14.6 7.3 80.5 4, 5, 6, 7, 9, 8, 3 Outcome standards at the system level HR18 HR19 3) HR20 HR21 HR22 HR23 3) Goal: reduced risk behaviour (reducing unsafe injections, unsafe drug use and unprotected sex) Goal: reduced substance use (treatment must be aimed at a reduction of substance use, e.g. helping the client/patient to reduce use or to abstain from psychotropic substances) Goal: referrals (treatment services must be prepared to refer clients/patients to other health/social/treatment/legal services if needed) Internal evaluation (services must regularly perform an internal evaluation of their activities and outcomes) External evaluation (services must regularly allow an evaluation of their activities and outcomes by an independent external evaluator) Utilisation monitoring (services must periodically report the occupancy rates of service slots) 133 39.8 18.8 35.3 3.8 2.3 94.7-131 24.4 20.6 33.6 13.7 7.6 59.5 4, 2, 6, 5, 1, 10, 9, 3, 7, 8 130 42.3 19.2 30.8 5.4 2.3 93.8 4 130 23.8 29.2 36.9 7.7 2.3 89.2 4 129 8.5 16.3 54.3 16.3 4.7 79.8 4, 10, 7 130 28.5 30.8 25.4 9.2 6.2 84.6 4, 5, 2, 3, 9 HR24 3) Cost-effectiveness ratio (positive outcomes, e.g. number of abstinent 129 4.7 16.3 40.3 26.4 12.4 50.4 2, 4, 3, 1, 7, 18 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.

patients in relation to service costs) 10, 9, 8, 5, 6 HR25 3) Cost-benefit ratio (tangible benefits, e.g. years of increased life expectancy in relation to service costs) 128 1.6 17.2 37.5 31.3 12.5 58.6 4, 3, 5, 10, 7, 8, 9, 2, 1, 6 1) 1= needle-syringe exchange, 2 = supervised injection room, 3 = outreach/street work, 4 = drug checking, 5 = BBV testing & counselling, 6 = vaccination, 7 = referrals, 8 = safer use counselling, 9 = safe sex counselling, 10 = sheltered housing. Note: exceptions are ordered from high to low relevance; 2) these MQS were reformulated during the conference, reformulations are marked in italics; 3) these MQS were definitively excluded from the list after the conference. Note: HR 1-3: These three standards were integrated into one MQS at the conference but were assessed separately in the online survey. HR6 and HR7 were integrated into one MQS and reformulated at the conference as described in HR6 in the table. 19 Schaub M, Uchtenhagen A & the EQUS expert group Eur Addict Res 19; 6: 314-324.