GRADUATE PHYSIOLOGY COURSE PSL 7030/7031 Winter, 2017; 4 credit hours Room: 2268 Scott Hall Hours: Mon 8:30-9:20 a.m.; Wed 8:30-9:20 a.m.; Fri 8:30-10:10 a.m. FACULTY Course Instructors: Instructor Steven Cala, Ph.D. Course Director Pat Mueller, Ph.D. Donal O Leary, Ph.D. Steve Keteyian, Ph.D. Jason Mateika, Ph.D. Stephen DiCarlo, Ph.D. Noreen Rossi, M.D. Daniel Walz, Ph.D. Email s.cala@wayne.edu pmueller@med.wayne.edu doleary@med.wayne.edu sketeyi@hfhs.edu jmateika@med.wayne.edu sdicarlo@med.wayne.edu nrossi@med.wayne.edu dwalz@med.wayne.edu Course Materials: The required reading course pack will be posted on Blackboard and will also be available for purchase at FEDEX/Kinko's Print Shop after the start of the class. Students should read and study the lecture notes, as well as PowerPoint presentations posted on Blackboard. You can download those notes or bring them to class on your electronic device. You may also purchase the set from Kinko s shortly after the class has begun. If you want to supplement these notes, the best complete reference is Medical Physiology (latest edition), by Boron, W.F. & Boulpaep, and E.L. Course Description: The course covers the cardiovascular physiology, pulmonary physiology, gastrointestinal physiology, renal physiology, and hemostasis. Subject matter is presented at a level roughly similar to that presented in the Medical Physiology Course (Year 1 Medical students). Where applicable, students will be provided with examples of diseases resulting from defects of the systems covered in the course. Students are expected to integrate the information provided into a wider understanding of human physiology. Learning Objectives: Students will become facile with concepts commonly used by medical professionals in discussing normal and disease states of the cardiovascular system, pulmonary system, gastrointestinal system, kidney, and blood. Students will be able to describe the physiological and biochemical mechanisms that control cardiac output, as well as basic physiological mechanisms underlying heart and vascular function; control of blood delivery to organ systems under varying physiological conditions; and regulation of blood pressure. Students will be able to describe the processes underlying the cardiac action potential, conduction through the heart, and the electrocardiogram. Students will be able to describe the physiological mechanisms that underlie the neural control of breathing, lung and chest wall mechanics, lung volumes/perfusion and the maintenance of acid base balance. Students will also be able to describe the physiological 1
mechanisms responsible for the control of breathing during exercise and sleep. Students will be able to describe the physiological mechanisms that underlie the four major functions of the GI tract: 1) motility, 2) secretion, 3) digestion and 4) absorption. Students will be able to describe the physiological mechanisms that underlie regulation of the kidney. Students will be able to explain homeostatic mechanisms across the nephron length, including mechanisms of acid-base homeostasis. Students will be able to describe neural control of renal function, and its neuroendocrine mechanisms of blood pressure regulation. Students will be able to describe the various cellular components of blood, contributions to homeostasis by blood, and mechanisms of clotting. Assessment of Learning Outcome: will be determined from exam grades. PSL7030 exams will consist of 3 multiple-choice questions per lecture hour, for a total of 150 questions for the course. Bubble sheets will be provided for each of the three exams. Erasing answers from the scantron sheet is not recommended; rather students are advised to first answer all questions on their exam and then transfer the answers onto the bubble sheet. Answer keys and individual student responses will be posted on Blackboard. All exam questions will count equally towards the course grade. The average grade is expected to be somewhere in the B or B+ range. Letter grades will be assigned based on percentage correct of all 150 questions. Final letter grades will be assigned by joint decisions of a committee, made of all instructors. Minimum requirements for letter grades otherwise follow University Grading System as follow: A 90% and above A- 85% B+ 80% B 75% B- 70% C+ 65% C 60% C- below 60% PSL 7031 exams will consist of a few questions from each instructor involving possible combinations of multiple choice, short answer, or essay. Essay responses should contain clearly written full sentences, without overuse of abbreviations, unless otherwise instructed. Responses must contain proper grammar and spelling. Students should concentrate on answering the question that is asked, without needless and irrelevant information. Exams will be graded by individual Instructors, and a percentage given that reflects how correctly and completely questions are answered. A score of 80% or greater will be considered a minimally passing grade (= B). Make-up exams will consist of a series of essay questions, at the discretion of Faculty, and will be given only for valid excuses: death, disaster, illness verified by physician, etc., and only if discussed with the Course Director prior to the exam. Make-up exams are severely restricted. Course and Instructor Evaluations Evaluation forms will be sent via your WSU email account by our university testing service after each of the three units, when you will be asked to provide 2
an evaluation for each Instructor in that unit. Please give us your feedback! We want to know what we are doing well and what areas of the course can still be further improved. Lecture Schedule: PSL 7030/7031 (Graduate Physiology) The following is the planned lectures and exam schedule. The course is a 4-credit course and meets in Room 2268 Scott Hall 4 hr per week. Please note that Exams 1-3 are held in the Green Auditorium in Scott Hall. PSL7030 students will be given 1 hr and 50 min to finish each Exam, whereas students taking the PSL7031 exams will be given 2 hr and 50 min Lecture schedule: M Jan 9 8:30-9:20 Cardiovascular Physiology 1 Cala W Jan 11 8:30-9:20 Cardiovascular Physiology 2 Cala F Jan 13 8:30-9:20 Cardiovascular Physiology 3 Cala 9:30-10:10 Cardiovascular Physiology 4 Cala M Jan 16 Martin Luther King observance NO CLASSES W Jan 18 8:30-9:20 Cardiovascular Physiology 5 Cala F Jan 20 8:30-9:20 Cardiovascular Physiology 6 Cala 9:30-10:10 Cardiovascular Physiology 7 Mueller M Jan 23 8:30-9:20 Cardiovascular Physiology 8 Cala W Jan 25 8:30-9:20 Cardiovascular Physiology 9 Cala F Jan 27 8:30-9:20 Cardiovascular Physiology 10 Cala 9:30-10:10 Cardiovascular Physiology 11 Mueller M Jan 30 8:30-9:20 Cardiovascular Physiology 12 O Leary W Feb 1 8:30-9:20 Cardiovascular Physiology 13 O Leary F Feb 3 8:30-9:20 Cardiovascular Physiology 14 O Leary 9:30-10:10 Cardiovascular Physiology 15 O Leary M Feb 6 8:30-9:20 Cardiovascular Physiology 16 O Leary W Feb 8 8:30-9:20 Cardiorespiratory fitness and clinical outcomes Keteyian F Feb10 8:30 -!0:20 Examination #1 Cardiovascular Physiology, Green Lecture Hall M Feb 13 8:30-9:20 Respiratory Physiology 1 Mateika W Feb 15 8:30-9:20 Respiratory Physiology 2 Mateika F Feb 17 8:30-9:20 Respiratory Physiology 3 Mateika 9:30-10:10 Respiratory Physiology 4 Mateika M Feb 20 8:30-9:20 Respiratory Physiology 5 Mateika W Feb 22 8:30-9:20 Respiratory Physiology 6 Mateika F Feb 24 8:30-9:20 Respiratory Physiology 7 Mateika 9:30-10:10 Respiratory Physiology 8 Mateika M Feb 27 8:30-9:20 Respiratory Physiology 9 Mateika W Mar 1 8:30-9:20 Respiratory Physiology 10 Mateika F Mar 3 8:30-9:20 Respiratory Physiology 11 Mateika 9:30-10:10 Respiratory Physiology 12 Mateika M Mar 6 8:30-9:20 Gastrointestinal Physiology DiCarlo W Mar 8 8:30-9:20 Gastrointestinal Physiology DiCarlo F Mar 10 8:30-9:20 Gastrointestinal Physiology DiCarlo 9:30-10:10 Gastrointestinal Physiology DiCarlo Mar 13 through Friday Mar 17 SPRING BREAK No Classes M Mar 20 8:30-9:20 Gastrointestinal Physiology DiCarlo W Mar 22 8:30-9:20 OPEN F Mar 24 8:30-10:20 Examination #2 Respiratory/Gastrointestinal Physiol., Green Lecture Hall M Mar 27 8:30-9:20 Renal Physiology 1 Rossi W Mar 29 8:30-9:20 Renal Physiology 2 Rossi F Apr 31 8:30-9:20 Renal Physiology 3 Rossi 9:30-10:10 Renal Physiology 4 Rossi M Apr 3 8:30-9:20 Renal Physiology 5 Rossi 3
W Apr 5 8:30-9:20 Renal Physiology 6 Rossi F Apr 7 8:30-9:20 Renal Physiology 6 Rossi 9:30-10:10 Renal Physiology 7 Rossi M Apr 10 8:30-9:20 Renal Physiology 8 Rossi W Apr 12 8:30-9:20 Renal Physiology 9 Rossi F Apr 14 8:30-9:20 Renal Physiology 10 Rossi 9:30-10:20 Renal Physiology 11 Rossi M Apr 17 8:30-9:20 Hemostasis Walz W Apr 19 8:30-9:20 Hemostasis Walz F Apr 21 8:30-9:20 Hemostasis Walz 9:30-10:10 Hemostasis Walz M Apr 24 8:30-9:20 Hemostasis Walz W Apr 26 8:30-9:20 Study Day F Apr 28 8:30-10:20 Examination #3 Renal/Acid-base balance/hemostasis, Green Lecture Hall UNIVERSITY POLICIES Religious holidays -- (from the online Academic Calendar): Because of the extraordinary variety of religious affiliations of the University student body and staff, the Academic Calendar makes no provisions for religious holidays. However, it is University policy to respect the faith and religious obligations of the individual. Students with classes or examinations that conflict with their religious observances are expected to notify their instructors well in advance so that mutually agreeable alternatives may be worked out. Student Disabilities Services -- (edited statement from the SDS web site): If you have a documented disability that requires accommodations, you will need to register with Student Disability Services for coordination of your academic accommodations. The Student Disability Services (SDS) office is located in the Adamany Undergraduate Library. The SDS telephone number is 313-577-1851 or 313-202-4216 (Videophone use only). Once your accommodation is in place, someone can meet with you privately to discuss your special needs. Student Disability Services' mission is to assist the university in creating an accessible community where students with disabilities have an equal opportunity to fully participate in their educational experience at Wayne State University. Students who are registered with Student Disability Services and who are eligible for alternate testing accommodations such as extended test time and/or a distraction-reduced environment should present the required test permit to the professor at least one week in advance of the first exam. Federal law requires that a student registered with SDS is entitled to the reasonable accommodations specified in the student s accommodation letter, which might include allowing the student to take the final exam on a day different than the rest of the class. Academic Dishonesty -- Plagiarism and Cheating (edited statement from the DOSO s web site): Academic misbehavior means any activity that tends to compromise the academic integrity of the institution or subvert the education process. All forms of academic misbehavior are prohibited at Wayne State University, as outlined in the Student Code of Conduct (http://www.doso.wayne.edu/studentconduct- services.html). Students who commit or assist in committing dishonest acts are subject to downgrading (to a failing grade for the test, paper, or other 4
course-related activity in question, or for the entire course) and/or additional sanctions as described in the Student Code of Conduct. Cheating: Intentionally using or attempting to use, or intentionally providing or attempting to provide, unauthorized materials, information or assistance in any academic exercise. Examples include: (a) copying from another student s test paper; (b) allowing another student to copy from a test paper; (c) using unauthorized material such as a "cheat sheet" during an exam. Fabrication: Intentional and unauthorized falsification of any information or citation. Examples include: (a) citation of information not taken from the source indicated; (b) listing sources in a bibliography not used in a research paper. Plagiarism: To take and use another s words or ideas as one s own. Examples include: (a) failure to use appropriate referencing when using the words or ideas of other persons; (b) altering the language, paraphrasing, omitting, rearranging, or forming new combinations of words in an attempt to make the thoughts of another appear as your own. Other forms of academic misbehavior include, but are not limited to: (a) unauthorized use of resources, or any attempt to limit another student s access to educational resources, or any attempt to alter equipment so as to lead to an incorrect answer for subsequent users; (b) enlisting the assistance of a substitute in the taking of examinations; (c) violating course rules as defined in the course syllabus or other written information provided to the student; (d) selling, buying or stealing all or part of an un-administered test or answers to the test; (e) changing or altering a grade on a test or other academic grade records. Course Drops and Withdrawals -- In the first two weeks of the (full) term, students can drop this class and receive 100% tuition and course fee cancellation. After the end of the second week there is no tuition or fee cancellation. Students who wish to withdraw from the class can initiate a withdrawal request on Pipeline. You will receive a transcript notation of WP (passing), WF (failing), or WN (no graded work) at the time of withdrawal. No withdrawals can be initiated after the end of the tenth week. Students enrolled in the 10 th week and beyond will receive a grade. Because withdrawing from courses may have negative academic and financial consequences, students considering course withdrawal should make sure they fully understand all the consequences before taking this step. More information on this can be found at: http://reg.wayne.edu/pdf-policies/students.pdf Please note: The last day to request to withdraw from this course is Sunday, March 26, 2017. Beyond this date, no requests to withdraw can be considered. Student Services The Academic Success Center (1600 Undergraduate Library) assists students with content in select courses and in strengthening study skills. Visit www.success.wayne.edu for schedules and information on study skills workshops, tutoring and supplemental instruction (primarily in 1000 and 2000 level courses). The Writing Center is located on the 2nd floor of the Undergraduate Library and provides individual tutoring consultations free of charge. Visit http://clasweb.clas.wayne.edu/writing to obtain information on tutors, appointments, and the type of help they can provide. Library research assistance -- Working on a research assignment, paper or project? Trying to figure out how to collect, organize and cite your sources? Wayne State librarians provide oncampus or online personalized help. Contact them at http:library.wayne.edu/consult 5
Class Recordings: Audio recordings of lectures will be made available after each lecture in Blackboard. On occasion, technical issues may arise that prevent the recordings from being available immediately following the lecture. Students are asked to be patient. 6