Curriculum Vitae Europass

1 Curriculum Vitae Europass Informatii personale Nume / Prenume Vălean Simona-Doina Adresa(e) Str. Stefan Mora 8/37, Cluj-Napoca, Romania Telefon(oane) Mobil 0747 55 38 45 Fax(uri) +40 264 590899 E-mail(uri) doina.valean@umfcluj.ro Nationalitate(-ati) Romana Data nasterii 03.04.1953 Sex F Locul de munca / Domeniul occupational Universitatea de Medicină şi Farmacie "Iuliu Haţieganu" Cluj-Napoca Facultatea de Medicină Departamentul Medicina Interna. Catedra Medicala I - Medicină internă, cardiologie şi gastroenterologie Conferențiar universitar, medic primar medicină internă şi gastroenterologie Gastroenterologie. Invățământ medical /activitate clinică /endoscopie digestivă/ /cercetare Experienta profesionala Perioada Prezent Functia sau postul ocupat Conferentiar universitar. Medic primar Medicina Interna si Gastroenterologie Numele si adresa angajatorului Universitatea de Medicină şi Farmacie Iuliu Haţieganu Cluj-Napoca, str. Emil Isac nr. 13, 400023, Cluj-Napoca, România, telefon: 0264 597 256, fax: 0264 597 257, website: www.umfcluj.ro Tipul activitatii sau sectorul de activitate Gastroenterologie. Invatamant medical /activitate clinica /endoscopie digestiva/ /cercetare Activitate didactica, domeniul gastroenterologie: curs si stagiu clinic, studenti anul IV, linia de studii in limba romana (din 1990) si in limba franceza (din 2005), indrumator lucrari de diploma; curs postuniversitar (2) si activitate clinica medicala practica cu medici rezidenti Activitate clinica si endoscopie digestiva, in cadrul Sectiei de Gastroenterologie a SCJU Cluj-Napoca Cercetare, domeniul gastroenterologie. Temele abordate predominant, pana in prezent: cancere digestive si factori de risc Participare/conducere granturi naţionale/internaţionale Da : cercetator in 2 granturi nationale (finalizate); colaborare la 2 proiecte internationale, sub egida SRGH (un proiect European (reprezentantul SRGH pentru initiative ERA in Romania ) si un proiect interinstitutional international,germania-romania, (coordonator national) ( in derulare) Educatie si formare Perioada 1978 Calificarea / diploma obtinuta Diploma de medic UMF Iuliu Hatieganu Cluj-Napoca Page 1 / 14 - Curriculum vitae of

Calificarea / diploma obtinuta 2 Perioada 1977-1980 : Internat IMF Cluj-Napoca medic intern, specialitati medicale 1980-1981: medic stagiar, Spitalul Orasenesc Simleu Silvaniei 1981-1990 Medic specialitatea medicina interna, personal cu studii superioare neatestat cercetarii, Institutul de Igiena si Sanatate Publica Cluj-Napoca, cu integrare la Laboratorul de Fiziopatologie Medicala si Ergonomie Nefrologie (1981-1984) si Clinica Medicala I (1984-1990) Perioada Calificarea / diploma obtinuta Perioada Calificarea / diploma obtinuta Perioada Calificarea / diploma obtinuta Perioada 1980-1984 : Secundariat I Medicina Interna Medic principal de specialitate Medicina Interna 1992 : Primariat I Medicina Interna Medic primar Medicina Interna 1991-1993: Secundariat II - Gastroenterologie Medic principal de specialitate Gastroenterologie 2004: Primariat II - Gastroenterologie Calificarea / diploma obtinuta Medic primar Gastroenterologie Perioada 1999: titlul stiintific de doctor in stiinte medicale, domeniul medicina. Titlul tezei: Cancerul gastric. Contributii la studiul unor aspecte de epidemiologie si anatomo-clinice, factori de risc si de prognostic, Conducator stiintific, Prof Dr Roman Vlaicu Perioada 1990-1995 Calificare Asistent universitar, Clinica Medicala I, Facultatea de Medicina si Farmacie, UMF IUliu Hatieganu Cluj- Napoca Perioada 1995-2004 Calificare Sef de lucrari, Clinica Medicala I, Facultatea de Medicina, UMF IUliu Hatieganu Cluj-Napoca Perioada 2004 si in prezent Calificare Conferentiar universitar, Clinica Medicala I, Facultatea de Medicina, UMF IUliu Hatieganu Cluj-Napoca Limba(i) straina(e) cunoscute Autoevaluare Intelegere Vorbire Scriere Nivel european (*) Ascultare Citire Participare la conversatie Discurs oral Exprimare scrisa Engleza B2 B2 B2 B2 B2 Franceza B2 B2 B2 B2 B2 (*) Nivelul Cadrului European Comun de Referinta Pentru Limbi Straine Page 2 / 14 - Curriculum vitae of

Informatii suplimentare Page 3 / 14 - Curriculum vitae of Activitate didactica, domeniul gastroenterologie: curs si stagiu clinic, studenti anul IV, linia de studii in limba romana si in limba franceza; cursuri postuniversitare (2) si activitate clinica cu rezidentii Activitate clinica si endoscopie digestiva, in cadrul Sectiei de Gastroenterologie a SCJU Cluj-Napoca, medic sef Sectie Gastroenterologie a SCJU (din 2015 si in prezent), Alte activitati: Presedinte al Comisiei de Etica a SCJU (din 2015 si in prezent), membru in Colegiul Medicilor la nivel de judet (2007-2015) si pe tara (2012 si in prezent) Am facut parte din comitetul de redactare a raportului CIDMEF 2002, al Facultatii de Medicina, a UMF Iuliu Hatieganu Am facut parte, repetat, din comisii de examen de specialitate/primariat ale MS Am raspuns pozitiv la toate solicitarile UMF (membru in comisii de rezidentiat, referent in comisii de doctorat) si ale Scolii Doctorale (analiza tezei evaluator) Membru al asociaţiilor profesionale Membru al Societatii Române de Gastroenterologie şi Hepatologie (SRGH) ; Membru al Societatii Române de Endoscopie Digestiva (SRED) ; Secretar general al Societatii Române de Gastroenterologie şi Hepatologie (SRGH) (din iunie2015) Membru in comitete de redactie ale unor reviste internationale ACTA ENDOSCOPICA. Revue Europeene de Formation Continue en Endoscopie/European Journal of Post Graduate Training in Endoscopy membru in comitetul international de redactie (1995-2007) HEGEL REVUE DE HEPATO-GASTROENTEROLOGIE LIBERALE (http:// irevues.inist.fr/hegel) membru in comitetul international de redactie (din 2012 si in prezent) Proiecte nationale de cercetare (2) in calitate de cercetator (Proiecte nationale CNCSIS, date anexate) Proiecte Europene de cercetare (2), in calitate de coordonator national de program, sub egida SRGH. (1).Colaborare la Proiectul European dedicat hepatitelor autoimune (HAI) (UEG National Societies LINK Award. Era Collaboration: European Registry on Autoimmune hepatitis, grant aprobat de catre UEG la 30 Ianuarie, 2016 (2). Colaborare la un proiect international Germania-Romania, intitulat Molekulargenetische Untersuchungen zur Identifikation vor ursachlichen Genen fur das Magenkarzinom ( Studii de genetica moleculara pentru identificarea genelor care intervin in geneza cancerului gastric ) initiat de Institut fur Humangenetik de Universitatsklinikums Bonn, PD Dr med Iohannes Schumacher, in 2013 si extins in Romania in 2016. Alte specializari: Endoscopie digestiva: Cluj-Napoca (1984), Strasbourg, Franta (1990,1992, 2006, 2007) Ecografie abdominala: Cluj-Napoca (1991,1999) Curs gastroenterologie Olanda (1993) Stagiu gastroenterologie, Tours, Franta, 1994 (bursa TEMPUS de 6 luni) Curs pedagogie: Cluj-Napoca, UMF (2002) Competente organizatorice/manageriale: Capacitate de organizare a muncii specifice, activitate medicala la patul bolnavului, explorari endoscopie digestiva Promovarea endoscopiei digestive, incepand cu anul 1985, organizarea si dotarea tehnica a laboratorului de endoscopie la Clinica Medicala I, al carui coordonator am fost in perioada 1985-2010, care a reprezentat unul dintre argumentele majore pentru infiintarea sectiei de gastroenterologie a SCJU. Organizator curs pentru medicii de familie, privitor la screening-ul pentru cancer colorectal (2002-2005), in cadrul unui program national care a functionat in aceasta peroada (realizare impreuna cu Prof Dr O Pascu si Prof Dr PA Mircea) Moderator sesiuni stiintifice Competente dobandite la locul de munca: O buna cunoastere a proceselor de control a calitatii, dobandite prin experienta personala indelungata in practica de spital si de invatamant Am participat la conferinta CONFLICT RESOLUTION DAY, EDITIA A II-a, 16.10.2015 (organizata sub egida Baroului Cluj, INPPA, IMNA, in colaborarea cu Colegiul Medicilor si Institutul Oncologic Cluj), centrata pe medierea in cazurile de malpraxis medical si informatii adiacente (raspunderea profesionala a personalului medical, negocierea contractelor de asigurare in domeniul medical, jurisprudenta nationala si comunitara in cazurile de malpraxis medical) Perfectionare continua a activitatii didactice, sub multiplele sale aspecte, informare si predare, prin studiu personal, colaborare profesionala, urmarirea dezvoltarilor didactice promovate de Facultatea de Medicina, modelul de curs integrat ( Integrated Medical Curriculum. Emediqual Summer school 2013. Modul hepatogastroenterologie) Competente legate de cercetare, castigate prin experienta personala, dublate de posibilitatile oferite la locul de munca, de experienta inaintasilor si a colegilor din departamentele medical conexe Competente informatice: cele strict necesare pentru redactare, comunicare si informatie. Permis conducere B Publicatii: Carti: 11 (prim autor 2; colaborator -9, dintre care 7 tratate nationale) Cursuri universitare: (colaborator) - 6 Lucrari stiintifice publicate: 143 (In extenso: prim autor-25, co-autor-23. In rezumat: prim autor-43, co-autor-52) Citari de catre alti autori: 17 (10 in strainatate si 7 in tara) 3

Anexe Anexa 1. Lista proiecte de cercetare 1. Lista proiecte de cercetare 2. Lista articole si capitole de carti publicate 4 PROIECTE GRANTURI DE CERCETARE NATIONALE, la care am participat si perioada Program/proiect Funcţie Perioada CNCSIS. cercetător 2005-2007 Stress-ul oxidativ în patologia eso-gastro-duodenală. Director proiect: Prof.dr.Adina Mureşan Valoare: 2mld ROL CNCSIS. Evaluarea non-invazivă a steatozei şi fibrozei hepatice din hepatopatiile cronice prin analiza computerizată a imaginilor ultrasonografice. Director proiect: Prof.dr.PA Mircea; cod CNCSIS 1414). Valoare: 200.000 RON cercetător 2006-2008 PRIECTE EUROPENE, la care particip si perioada in derulare: 2 (documente anexate) Program/Proiect Functie Perioada UEG National Societies LINK Award. Era Collaboration: European Registry on Autoimmune hepatitis, grant aprobat de catre UEG la 30 Ianuarie, 2016. Coordonatori proiect: Ynto de Boer (Amsterdam, Olanda), Rodrigo Liberal (Londra, Anglia). Reprezentantul Societatii Romane de Gastroenterologie si Hepatologie (SRGH), in programul UEG,ERA initiative in Romania 2016-2018 Program/Proiect Functie Perioada Molekulargenetische Untersuchungen zur Identifikation von ursächlichen Genen für das Magenkarzinom (Studii de genetica moleculara pentru identificarea genelor care cauzeaza cancerul stomacului). Coordonator proiect: PD dr. Med Johannes Schumacher, Institut für Humangenetik des Universitätsklinikums Bonn, studiu initiat in anul 2013 si extins in Romania in anul 2016 Coordonator national, sub egida Societatii Romane de Gastroenterologie si Hepatologie (SRGH) 2016- Anexa 2. Lista articole si capitole de carte publicate Cărţi publicate : 11 Prim autor : 2 1.Simona Vălean, Mircea Cucuianu. PORFIRIILE. Biochimie, etiopatogeneză, forme clinice, tratament. Ed. Medicală Universitară Iuliu Haţieganu Cluj-Napoca, 2003 (citat de alti autori: 4) 2. Simona Vălean. Cancere digestive. Epidemiologie si factori de risc, strategii de screening si supraveghere. Ed. Medicală Universitară Iuliu Haţieganu Cluj-Napoca, 2011 Colaborator - Capitole publicate in tratate nationale (10) si alte carti (2) : 12 3. TRATAT DE GASTROENTEROLOGIE CLINICA (sub red. M Grigorescu, O Pascu). Ed. Tehnică, Bucureşti, vol. I 1996 (capitole redactate : Esofagoscopia - pag. 193-199 ; Gastroscopia pag. 273-282) 4. TRATAT DE GASTROENTEROLOGIE CLINICA (sub red. M Grigorescu, O Pascu). Ed. Tehnică, Bucureşti, vol. II 1997 (capitol redactate : Porfiriile pag.479-495) (citari de alti autori: 3) 5. TRATAT DE GASTROENTEROLOGIE. M Grigorescu (ed). Ed. Medicală Naţională, Bucureşti, 2001 (capitole redactate : Durerea abdominala pag. 46-63) 6. TERMINOLOGIA STANDARDIZATA IN ENDOSCOPIA DIGESTIVA. M Delvaux (ed). Ediţie bilingvă. Traducători: O Pascu, Simona Vălean. Ed. Tipoholding SA, Cluj-Napoca, 2002 7. TRATAT DE HEPATOLOGIE. M Grigorescu (ed). Ed. Medicală Naţională, Bucureşti, 2004 (capitol redactat: Porfiriile pag.714-729) 8. TRATAT DE ONCOLOGIE DIGESTIVA. Grigorescu M, Irimie A, Beuran M (ed), Bucuresti: Editura Academiei Romane, 2013 (capitol redactat: Cancerul gastric. Epidemiologie generala. Factori de risc, screening si supraveghere, pag: 312-336) 9. CURS INTENSIV DE BOLI DIGESTIVE. Stanciu C, Balan G, Prelipcean CC, Trifan A (ed). Iasi: Editura Gr T Popa, 2013 (capitol redactat: Carcinomul hepatocelular. Epidemiologie descriptiva si tendinte evolutive, pag: 25-36) 10. TRATAT DE ONCOLOGIE DIGESTIVA. Grigorescu M, Irimie A, Beuran M (ed), Bucuresti: Editura Academiei Romane, 2014 (capitole redactate: Cancerul hepatic. Epidemiologie generala. Factori de risc, screening si supraveghere, pag: 25-42 si Profilaxia carcinomului hepatocelular, pag: 344-359) 11. TRATAT DE ONCOLOGIE DIGESTIVA. Grigorescu M, Irimie A, Beuran M (ed), Bucuresti: Editura Academiei Romane, 2015 (capitole redactate: Cancerul colorectal. Epidemiologie generala si factori de risc, pag. 137-1560; Adenocarcinomul intestinului subtire. Epidemiologie generala si factori de risc, pag. 26-35. Page 4 / 14 - Curriculum vitae of

Cursuri universitare: 6 (colaborator) 5 1. MEDICINA INTERNA PNEUMOLOGIE. Olinic N, Mircea PA, Blaga S, Comes L, Vida-Simiti L, Vălean S, Olinic D. Curs universitar Medicala I. Litografia UMF 1993 (capitol redactat: Bronsita acuta) 2. SCREENING-UL CANCERULUI COLORECTAL (curs postuniversitar pentru medicii de familie) PA Mircea, O Pascu, Simona Vălean (eds). Ed Medicală Universitară Iuliu Haţieganu Cluj-Napoca, 2004 3. MEDECINE INTERNE Gastroentérologie-Hépatologie-Métabolisme et nutrition-rhumatologie (notes de cours) PA Mircea, Simona Vălean. Curs universitar, anul V Medicina (linia limba franceză). Ed Medicală Universitară Iuliu Haţieganu Cluj-Napoca, 2005 4. MEDICINA INTERNA. PATOLOGIA APARATULUI RESPIRATOR. Mircea PA, Blaga S, Vida-Simiti L, Comes L, Olinic D, Vălean S. Ed Medicala Universitara Iuliu Hatieganu Cluj-Napoca 2005 (capitol redactat: Explorari urilizate in patologia aparatului respirator) 5. Integrated Medical Curriculum. Emediqual Summer school 2013. Modul hepato-gastroenterologie. (curs sustinut si redactat: Diareea) 6. GASTROENTEROLOGIE & HEPATOLOGIE. Notes de cours pour les étudiants en médecine. II-ème édition. Mircea PA, Vălean S. Editura Medicala Universitara Iuliu Hatieganu Cluj-Napoca, 2014 Lucrari stiintifice publicate total 143 Lucrări ştiinţifice publicate: in extenso prim autor - 25 Lucrări ştiinţifice publicate in extenso în străinatate prim autor: 4 Prim autor: 4 1.Vălean S, Vlaicu R, Ionescu I. Treatment of gastric ulcer with carbonic anhydrase inhibitors. Annals of the New York Academy of Science, vol 429, Biology and Biochemistry of the Carbonic Anhydrases. Ann N Y Acad Sci.1984;429:597-600 (citat de alti autori: 1,4) BDI (IF=4.38 in 2016) 2. Simona Valean, R Vlaicu, NG Ionescu. Traitement de l ulcère gastrique aux inhibiteurs enzymatiques. Archives de L Union Médicale Balkanique, tome XXIII, no.1-4, Ian-Aout 1985:36 (BDI) 3. Simona Vălean, M Cazacu, C Bungardean, M Petrescu, S Encica, D Gheban, CD Olinici, O Fraticiu, V Porumb, S Pop, A Catinean, R Chira, PA Mircea. Hémoragie digestive de cause rare : hétérotopie pancréatique gastrique, lipome gastrique et tumeur stromale duodénale. A propos de trois cas cliniques. Acta Endoscopica 2002 ;32(5) :805-15. IF=0.16 4. Simona Valean, Jean-Claude Barbare. Incidence et mortalite du cancer primitif du foie en Roumanie en 2012. Hegel 2014 ;4(3) :256-62 Lucrări ştiinţifice publicate in extenso în ţară prim autor: 15 Prim autor: 15 1. Pop Simona, Cornelia Onesciuc. Hepatita virala de tip B cu transmitere neparenterala. Clujul Medical 1979 2. Simona Vălean, Y Bacq, L Pery, E Metman. Les infections spontanées du liquide d ascite à Listeria Monocytogenes. A propos de cinq cas et revue de la litterature. Rom J Gastroenterol 1995; 4(2): 101-6 3. Simona Vălean, D Malide, F Niculescu, H Rus, Magda Petrescu, D Olinici, A Ban, Adina Lariu, P Mircea, R Vlaicu. Chronic gastritis in gastric cancer patients. Immunohistochemical expression of carcinoembryonic antigen in benign and malignant gastric lesions.. Rom J Gastroenterol 1997; 6(4): 229-34 4.Simona Vălean, Magda Petrescu, D Olinici, A Ban, Adina Lariu, P Mircea, O Pascu, R Vlaicu. Early gastric cancer : a clinicopathologic study. Rom J Gastroenterol 1998;7(4):263-8 5.Simona Valean, Magda Petrescu, D Olinici, Diana Onea, R Chira, PA Mircea. Infecţia cu Helicobacter pylori, apreciată prin metoda histologică, la pacienţii cu cancer gastric comparativ cu pacienţii cu ulcer peptic şi gastrită cronică. Romanian J Pathol 1999;3&4:302-9 6. Simona Vălean, Magda Petrescu, CD Olinici, A Ban, E Dumitru, R Buiga, O Pascu, PA Mircea, R Vlaicu. Incidenta cancerului gastric in 1995 comparativ cu 1985 in Cluj. Aspecte anatomo-clinice. Jurnalul Român de Patologie 1999;3(1): 91-8 (Citari de alti autori : 2) 7. Simona Vălean, E Dumitru, D Farcas, S Pop, PA Mircea, R Vlaicu. Trends of gastric cancer mortality in Romania and Cluj county between 1955-1995. Rom J Gastroenterol 1999: 8(3): 165-70 8. Simona Vălean, M Tantau, Adina Lariu, Magda Petrescu, CD Olinici, A Ban, S Pop, PA Mircea, O Pascu. Time trends of peptic ulcer diagnosis as compared to gastric carcinoma and chronic gastritis in an endoscopic population. Rom J Gastroenterol 2000: 9(1): 15-9 9. Simona Vălean, A Cucuianu, Anca Cristea, Mariana Patiu, Magda Petrescu, Daniela Roman, V Negrean, R Chira, P Mircea. Liver cirrhosis and multiple myeloma : two case reports. Rom J Gastroenterol 2001;10(1): 55-60 10. Simona Vălean, Magda Petrescu, A Catinean, R Chira, PA Mircea. Pill esophagitis. Rom J Gastroenterol 2005; 14(2): 159-63. 11. Simona Vălean, PA Mircea, Lavinia Oprea et al. Trends of mortality rates from gastric cancer and colorectal cancer in Romania, 1955-2003. J Gastrointestin Liver Dis 2006:15(2): 111-5. BDI 12. Simona Vălean, Dana Damian, A Tataru, T Zaharia, PA Mircea, M Grigorescu. Porphyria cutanea tarda, a metabolic disease. Role of hepatitis C virus infection. Rom J Hepatol 2007 ;3(1) :52-58. ISI 13. Simona Valean, Petru Armean, Simona Resteman, Georgiana Nagy, Adina Muresan, Petru A Mircea. Cancer mortality in Romania, 1955-2004. Digestive sites: esophagus, stomach, colon and rectum, pancreas, liver, gallblader and biliary tree. J Gastrointestin Liver Dis 2008;17(1): 9-14 (citat de alti autori: 6-17). ISI 14. Simona Valean, Chris JJ Mulder, Oliviu Pascu, et al. WGO Digestive Oncology Task Force : Validation of hepatogastroenterologist practice in oncology. J Gastrointestin Liver Dis 2012;21(3):239-42 ISI. IF=1,855 15.Simona Valean, Monica Acalovschi, Mircea Diculescu, Mircea Manuc, Adrian Goldis, Catalin Sfarti, Anca Trifan. Mortality in digestive cancers, 2012: International data and data from Romania. J Gastrointestin Liver Dis 2015;24(4):507-14. ISI. IF=1,891 (2014) Page 5 / 14 - Curriculum vitae of

Alte publicatii : 6 1.Simona Valean. Chronic gastritis in gastric cancer patients. Immunohistochemical expression of carcinoembryonic antigen in benign and malignant gastric lesions. Letter to the editor. Reply. Rom J Gastroenterol 1998;7(1):82 2.Simona Valean. Early gastric cancer : a clinicopathologic study. Letter to the editor. Reply. Rom J Gastroenterol 1999;8(1) 3.Simona Valean, Andrei Cucuianu. Liver cirrhosis and multiple myeloma : two case reports. Letter to the editor. Reply. Rom J Gastroenterol 2001;10(3):265-8 4.Simona Valean. Congress report. UEGW Brussels, 2000. Rom J Gastroenterol 2001;10(1): 79-82 5.Simona Valean, Monica Lencu. Congress report. Les Journees Francophones de Pathologie Digestive, 2003, Paris. Rom J Gastroenterol 2003;12(2):163-7 6.Simona Valean. Editorial news. Tratat de Ultrasonografie Clinica, vol 3. Editors: Badea RI, Dudea SM, Mircea PA, Stamate M. Editura Medicala Bucuresti, Romania 2008. Medical Ultrasonography 2008, 10(1):59. ISI Lucrări ştiinţifice publicate in extenso în străinătate co-autor : 6 1.Puscas I, Buzas G, Sturzu D, Valean S. Effect of verapamil on purified bovine carbonic anhydrase. An in vitro study. Arzneimittelforschung 1984;34(9):946-7. IF=0.70 2.Puscas I, Valean S. Inhibition de l anhydrase carbonique de la muqueuse gastrique par la Cimetidine et la Ranitidine. Archives de L Union Medicale Balkanique, tome XXIII, no. 1-4, Ian-Aout 1985 3.Dindelegan D, Valean S, Contrasiu P, Voicu L, Puscas I. L effet des selles inorganiques de Mg en comparaison avec les composes organiques de Mg sur la secretion gastrique acide chez l homme. Archives de L Union Medicale Balkanique, tome XXIII, no. 1-4, Ian-Aout 1985 4.Puscas I, Reznicek A, Buzas G, Milas D, Kovacs E, Sturzu D, Persa F, Nemes-Brates R, Valean S. Ulcosilvanil an inhibitor of carbonic anhydrase associated with adrenergic beta-blockers in the treatment of duodenal ulcers. Med Interne 1986;24(1):75-9 5.Ouyahya F, Valean S, Bourlier P, Grangeponte M-C, Metman E-H. La polypose recto-colique familiale ne s est pas confirme, mais la colectomie etatit justifiee. Medical Staff gastro 1996;39:5-7 6. Nagy G, Gordan M, Vlaicu A, Mircea PA, Crisan D, Valean S. A reduced computational complexity method in non-invasive evaluation of hepatic steatosis and fibrosis by ultrasound image analysis using support vector machines. In: Zwiggelaar R, Labrosse F (eds). Medical Image Understanding and Analysis 2007 (the 11th conference):76-80 Lucrări ştiinţifice publicate in extenso în țară co-autor : 17 1.Puscas I, Buzas G, Valean S. Inhibitorii anhidrazei carbonice in asociere cu blocantele beta-adrenergice in tratamentul ulcerelor gastroduodenale. Medicina Interna, 1985 2.Uza G, Valean S, Pavel O, Iancu A, Vlaicu R. Magneziul seric in HTA esentiala stadiul II. Clujul Medical, 1987 3.Blaga S, Valean S, Olinic D, Pop S, Olinic N. Dinamica modificarilor clinice, electrocardiografice si ecografice intr-o cardiomiopatie hipertrofica familiala. Clujul Medical, 1995 4.Mircea PA, Pop S, Valean S, Chira R, Dudea S. Pseudotumoral images in liver ultrasonography. Rom J Gastroenterol 1997;6(4):277-85 5.Mircea PA, Valean S, Pop S, Guttman T, Granescu S, Iancu C, Pascu O. Giant gastric trichobezoar (case report). Rom J Gastroenterol 1997;6(1):43-6 6.Chira R, Mircea PA, Suteu M, Valean S, Onea D, Kerekes T, Olinic N. Hematom hepatic posttraumatic abcedat tratat prin drenaj percutan ecoghidat. Rev Rom Ultrasonografie 1999;1(1):141-4 7. Mircea PA, Chira R, Pop S, Valean S, Galatar N, Duma M, Petrescu M, Benatre A, Olinic N. Biopsia ecoghidata a tumorilor abdominale. Comparatie intre rezultatele obtinute cu 3 tipuri diferite de ace. Rev Rom Ultrasonografie 2000;2(3):237-44 8. Mircea PA, Chira R, Pop S, Valean S, Cucu A. Chistul hidatic hepatic mai multe fete ale aceleiasi afectiuni. Rev Rom Ultrasonografie 2000;2(2):155-67 9. Mircea PA, Chira R, Pop S, Valean S, Galatar N, Duma M, Petrescu M, Kerekes T, Benatre A, Olinic N. Biopsia ecoghidata in patologia tumorala abdominala: factori de performanata independenti de tipul si calibrul acelor de biopsie. Rev Rom Ultrasonografie 2001;3(1):30-47 10. Mircea PA, Valean S, Catinean A, Chira R. Ulcer gastric atipic profund la o tanara in varsta de 18 ani. Rev Rom Ultrasonografie 2001;3(3):227-32 11. Nagy G, Gordan M, Crisan D, Valean S, Vlaicu A, Mircea PA. Evaluarea non-invaziva a steatozei hepatice prin analiza computerizata a imaginilor ecografice. Rev Rom Ultrasonografie 2007;9(1):39-44 12. Nagy G, Gordan M, Vlaicu A, Mircea PA, Crisan D, Valean S. Non-invasive evaluation of hepatic steatosis by ultrasound image analysis with simple brightness features and support vecor machines. Acta Electrotehnica (special issue) 2007;48(4):217-22 13.Mânzat Săplăcan R, Mircea PA, Vălean S, Miu N, Burac L, Vălean C, Nanulescu M. The Long-term Evolution of Chronic Hepatitis B Acquired in Childhood. J Gastrointest Liver Dis 2009; 18(4): 433-438. ISI IF = 1.265 14.Mânzat Saplacan RM, Catinean A, Manole S, Valean SD, Chira RI, Mircea PA. Posttraumatic gastric wall hematoma in a patient under anticoagulant therapy. Case report and literature review. Med Ultrason. 2011 Jun;13(2):165-70. IF=1.11 15.Bintintan A, Chira RI, Bintintan VV, Nagy GA, Manzat-Saplacan MR, Lupsor-Platon M, Stefanescu H, Duma MM, Valean SD, Mircea PA. Value of hepatic elastography and Doppler indexes for predictions of esophageal varices in liver cirrhosis. Med Ultrason 03/2015;17(1):5-11. IF=1.11 16. Mânzat Saplacan RM, Balacescu L, Gherman C, Visan S, Chira R, Bintintan A, Nagy G, Popovici C, Valean SD, Craiu A, Bintintan V, Scurtu R, Mircea PA, Berindean-Neagoe I, Ciuleanu TE, Balacescu O. Is there a correlation between peripheral blood expression of angiogenic transcriptional factors/receptors and colorectal cancer? Journal of B.U.ON (official journal of Balkan Union of Oncology) 2015; 20(5):1193-2000 (IF=0.74) 17. Nagy G, Munteanu M, Valean S, Crisan D, Iancu M, Mircea PA. Hepatic steatosis and viral hepatitis B and C: role of metabolic syndrome. The 49 th Annual Scientific Meeting of the European Society of Clinical Investigation (ESCI) 2015, Cluj-Napoca. European Journal of Clinical Investigation 2015;45(suppl.2): pag.16 (Abstract Book. Conference paper) Page 6 / 14 - Curriculum vitae of 6

7 Lucrări ştiinţifice publicate in rezumat, în țară: prim autor - 34 1.Valean S, Voicu L. Compusii de magneziu in tratamentul ulcerelor gastro-duodenale. Simpozionul International Progrese in fiziopatologia si tratamentul ulcerelor gastro-duodenale, Felix, Romania 1985. Conference paper. Vol. Rez. pag. 336 2.Valean S, Vlaicu R. Aportul endoscopiei in diagnosticul etiologic al hemoragiilor digestive superioare. Zilele Medicale Balcanice, Cluj-Napoca, 1985, Vol Rez 3.Valean S, Cardan E, Vlaicu R, Ionescu NG. Tratamentul ulcerelor gastrice cu Ulcosilvanil. Al V-lea Congres National de Gastroenterologie, Bucuresti 1986. Vol. Rez. pag. 350 5.Valean S, Malide D, Olinici D, Petrescu M, Mircea P, Vlaicu R. Incidence of diffuse chronic gastritis and its histopathological types in patients with gastric ulcer and gastric cancer. Al VI-lea Congres National de Gastroenterologie si I-ul Congres National de Endoscopie, Bucuresti 1991. Rom J Gastroenterol 1991;Suppl 1, pag 9. 6.Valean S, Mircea P, Vlaicu R, Olinic N. Esofagita de reflux relatia cu secretia gastrica acida si bolile asociate. Simpozionul de Gastroenterologie si Endoscopie, Iasi 1992. Vol.Rez. pag.39 7.Valean S, Malide D, Niculescu F, Rus HG, Petrescu M, Olinici D, Mircea P, Vlaicu R, Olinic N. Immunohistochemical expression of CEA in benign and malignant gastric lesions. Simpozionul National de Gastroenterologie si Endoscopie, Cluj, 1993. Vol.Rez.pag. 20 (poster S12) 8.Valean S, Mircea P, Dosan L, Deacu R, Vlaicu R, Olinic N. Observatii asupra leziunilor eso-gastro-duodenale induse de aspirina si AINS. Zilele UMF Cluj-Napoca, 1993. Vol.Rez.pag.38 9.Valean S, Mircea P, Mic M, Marian I, Vlaicu R, OlinicN. Manifestari eso-gastrice ale hipertensiunii portale la bolnavii cu ciroza hepatica. Zilele UMF Iuliu Hatieganu Cluj-Napoca 1994. Vol. Rez. pag. 126 10.Valean S, Mircea P, Suteu M, Milas D, Olinici CD, Petrescu M, Buiga R, Dumitru E, Bolosiu HD, Funariu G, Olinic N. Cancerul gastric aspecte anatomo-clinice. Zilele UMF Cluj-Napoca, 1995. Vol.Rez.pag.65 11.Valean S, Milas D, Suteu M, Dumitru E, Buiga R, Petrescu M, Olinici D, Mircea P, Baraian I, Bolosiu HD. Cancere digestive aspecte anatomoclinice. Studiu retrospectiv pe 2 ani la pacienti spitalizati. Al VII-lea Congres National de Gastroenterologie si al II-lea Congres National de Endoscopie Digestiva, Bucuresti 1995. Vol.Rez. 12.Valean S, Mircea P, Covaciu C, Olinic N. Clinical and epidemiological data in chronic alcoholic liver disease. The 6th National Congres of Hepatology, Timisoara, 1996. Vol Rezumate, pag 124 (93/12) 13.Valean S, Petrescu M, Olinici D, Ban A, Veres A, Mircea P, Pascu O. Incidenta si prevalenta relativa a carcinomului gastric in Cluj, in 1995 comparativ cu 1985. Al VI-lea Congres National de Hepatologie, Timisoara 1996. Vol.Rez.pag.155 14.Valean S, Fontul M, Mircea P, Pop D, Olinici D, Petrescu M, Olinic N. Frecventa asocierii infectiei cu Helicobacter pylori la pacientii cu gastrita cronica, ulcer gastric, ulcer duodenal si stomac operat si leziunile histologice asociate. Simpozionul National de Gastroenterologie si Endoscopie Digestiva, Sinaia 1996. Vol.Rez.pag.7 15.Valean S, Lariu A, Mircea P, Vlaicu R, Olinic N. Profilul clinic al ulcerului peptic si optiunea pentru tratament medical/chirurgical in 1995 comparativ cu 1990. Simpozionul National de Gastroenterologie si endoscopie digestiva, Sinaia 1996, Vol Rezumate, pag.28 16.Valean S, Mircea PA, Tantau M, Chiorean M, Pascu O, Ban A, Petrescu M, Cristea A, Dobre C, Iuhos A, Vlaicu R, Olinic N. Profilul anatomoclinic si frecventa bolilor inflamatorii ale intestinului intr-un serviciu de medicina interna. Simpozionul National al Societatilor Romana de Gastroenterologie si Endoscopie Digestiva, Targu Mures 1997. Romanian J of Gastroenterol 1997;6(Suppl 1):pag.11 17.Valean S, Mircea P, Petrescu M, Olinici CD, Chira R, Onea D. Boala Whipple: case report. Al 8-lea Congres National de Gastroenterologie si al 3-lea Congres National de Endoscopie Digestiva, Timisoara 1999.Romanian J Gastroenterol 1999;8(Suppl1): pag 62 18.Valean S, Mircea P, Petrescu M, Olinici CD, Chira R, Onea D. Helicobacter pylori infection in patients with peptic ulcer disease, chronic gastritis and gastric remnant as compared to patients with gatric cancer. Al 8-lea Congres National de Gastroenterologie, Timisoara 1999. Rezumate. Romanian J of Gastroenterology 1999;8(Suppl1): pag 50 19.Valean S, Mircea P, Popescu D, Gombosiu C, Chira R, Olinic N. Hemoragia digestiva superioara in 1990 comparativ cu 1999 frecventa, cauze, mortalitate. Zilele UMF Iuliu Hatieganu, Cluj-Napoca, 2000. Vol.Rez.pag.83 20.Valean S, Mircea P, Olariu C, Catinean A, Ionescu C, Chira R, Olinic N. Ulcerul peptic in 1990 comparativ cu 1999 frecventa, aspecte anatomoclinice, tratament. Zilele UMF Iuliu Hatieganu, Cluj-Napoca, 2000. Vol. Rez. pag. 84 21.Valean S, Petrescu M, Catinean A, Chira R, Mircea P. Infectia cu Helicobacter pylori la pacientii cu ulcer peptic complicat cu hemoragie digestiva superioara Forrest III, comparativ cu pacientii cu ulcer necomplicat. Zilele UMF Iuliu Hatieganu Cluj, 2002. Vol.Rez.pag.106 Page 7 / 14 - Curriculum vitae of

22.Valean S, Cristea A, Veres A, Patiu I, Catinean A, Mircea P, Gherman-Caprioara M. Helicobacter pylori in hemodialysis patients. Zilele UMF Iuliu Hatieganu, Cluj-Napoca, 2003. Vol Rezumate pag. 119 23.Valean S, Veres A, Cristea A, Catineanu A, Patiu M, Mircea P, Mirela Gherman-Caprioara. Dispepsia la pacientii dializati cronic. Al 3-lea Congres National de Nefrologie, Cluj 2003. Vol.Rez 8 24.Valean S, Petrescu M, Catinean A, Chira R, Mircea PA. Esofagita postmedicamentoasa: cazuri clinice. Romanian Journal of Gastroenterology 2004, 13, Suppl.1, pag.91 (poster PO44) 25.Valean S, Vlaicu S, Mircea PA, Chira R, Damian O. Esofagita de reflux: prezenta, severitate si afectiuni eso-gastro-duodenale concomitente, la o populatie endoscopica. Rezumate. Romanian Journal of Gastroenterology 2005, 14, Suppl.1, pag.27 (prezentare orala) 26.Valean S, Armean P, Nagy G, Mircea PA. Cancer mortality in Romania, 1955-2004. Digestive sites. Al 27-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva, Poiana Brasov, 2006. Rezumate. Journal of Gastrointestinal and Liver Diseases 2006;15(Suppl 1):pag. 55. BDI 27.Valean S, Farcau D, Bintintan A, Catinean A, Chira R, Mircea PA. Infectia cu Helicobacter pylori in relatie cu varsta si patologia benigna gastroduodenala, la o populatie endoscopica. Al 28-lea Simopozion National de gastroenterologie, Hepatologie si Endoscopie Digestiva, Sibiu, 2007. Journal of Gastrointestinal and Liver diseases 2007;16(Suppl 1):pag. 39 (prezentarea poster G. 11).ISI 28.Valean S, Chira R, Catinean A, Popovici C, Vlaicu S, Mircea PA. Cancerul de colon familial. Ancheta epidemiologica anamnestica. Al X-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Iasi, 2008. Journal of Gastrointestinal and Liver Diseases 2008;17(Suppl 1):pag. 76 (prezentare poster). ISI 29.Valean S, Vlaicu S, Nagy G, Chira R, Catinean A, Popovici C, Mircea PA. Cancer colorectal sporadic sau familial. Studiu anamnestic la 96 pacienti, utilizand criteriile Amsterdam. Al 29-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva, Cluj-Napoca, 2009. Rezumate. Journal of Gastrointestinal and Liver Diseases 2009;18(Suppl 1):pag. 11 (O12). ISI IF = 1,265 30.Valean S, Mircea PA, Crisan D, Petrescu M. Sporadic colorectal cancer or hereditary Lynch syndrome: anamnestic epidemiologic study using Amsterdam and Bethesda criteria. Al XXX-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva, Craiova, 2010. Rezumate. Journal of Gastrointestinal and Liver Diseases 2010;19(Suppl 1):pag. 32 (ME11). ISI IF = 1,434 31.Valean S, Martura S, Farcau D, Parvan A, Miu N, Petrescu M, Mircea PA. Helicobacter pylori infection related to age and benign gastroduodenal diseases in an endoscopic popoulation. Al XXX-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva, Craiova, 2010. Rezumate. Journal of Gastrointestinal and Liver Diseases 2010;19(Suppl 1):pag. 92 (G39).ISI IF = 1,434 32. Valean S, Farcau D, Miu N, Parvan A, Petrescu M, Martura S, Mircea PA. Helicobacter pylori infection and age in an endoscopic population. Al XXXIII-lea Congres National de Gastroenterologie si Hepatologie, Timisoara, 2013. Journal of Gastrointestinal and Liver Diseases 2013;22(suppl.1):pag 48 (oral presentation OP74). ISI IF= 1,849 33. Valean S, Mircea PA. Hepatocarcinoma time trends in Romania, 1980-2008: valuation of IARC/OMS and Globocan statistics. Al XXXIII-lea Congres National de Gastroenterologie si Hepatologie, Timisoara, 2013. Journal of Gastrointestinal and Liver Diseases 2013;22(suppl.1):pag 121 (poster presentation PP117). ISI IF= 1,849 34.Valean S, Istrati M. Decreasing trend of gastric cancer mortality in Romania, 1955-2012, before and after the era of Helicobacter pylori. Al XXXVI-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Cluj-Napoca, 2016. Journal of Gastrointestinal and Liver Diseases, 2016;25(Suppl 2): pag.178 (IV.170). ISI IF = 1,891 Lucrări ştiinţifice publicate in rezumat, în țară (selecții): co-autor -41 1.Vlaicu R, Valean S. Efectul nifedipinei asupra secretiei gastrice acide si ulcerelor duodenale complicate cu insuficienta evacuatorie gastrica functionala. Simpozionul International Progrese in fiziopatologia si tratamentul ulcerelor gastro-duodenale, Felix, Romania 1985, Vol. Rez. pag. 342 2.Puscas I, Nemes R, Persa F, Reznicek A, Valean S. Efectul antagonistilor beta-2 adrenergici asupra secretiei gastrice acide la bolnavii cu ulcer duodenal. Simpozionul International Progrese in fiziopatologia si tratamentul ulcerelor gastro-duodenale, Felix, Romania 1985, Vol. Rez. pag. 235 3.Puscas I, Reznicek A, Milas D, Valean S. Efectul antagonistilor beta-1 si beta-2 adrenergici asupra secretiei gastrice acide si activitatii anhidrazei carbonice din mucoasa gastrica la bolnavii cu ulcer duodenal. Simpozionul International Progrese in fiziopatologia si tratamentul ulcerelor gastroduodenale, Felix, Romania 1985, Vol. Rez. pag. 233 4.Voicu L, Contrasiu P, Valean S, Ciupe R, Pop I, Butan M, Marinescu I. Tratamentul ulcerelor duodenale cu etoxolamida, un inhibitor al anhidrazei carbonice din mucoasa gastrica. Studiu multicentric. Simpozionul International Progrese in fiziopatologia si tratamentul ulcerelor gastro-duodenale, Felix, Romania 1985, Vol. Rez. pag. 36 5.Contrasiu P, Dindelegan D, Calinici G, Fenyes G, Voicu L, Valean S. Inhibitorii anhidrazei carbonice in tratamentul ulcerului gastric. Studiu multicentric. Simpozionul International Progrese in fiziopatologia si tratamentul ulcerelor gastro-duodenale, Felix, Romania 1985, Vol. Rez. pag. 76 6.Mircea PA, Galatar N, Duma M, Dosan L, Olinic D, Valean S, Vlaicu R. Echoguided fine-needle histological biopsy in the diagnosis of abdominal tumors. Al VI-lea Congres National de Gastroenterologie si I-ul Congres National de Endoscopie, Bucuresti 1991. Rom J Gastroenterol 1991;Suppl 1, pag 7.Mircea PA, Cucu A, Valean S, Kerekes T, Vlaicu R. Pseudotumoral liver hydatid cysts: sonographic diagnostic criteria. Al VI-lea Congres National de Gastroenterologie si I-ul Congres National de Endoscopie, Bucuresti 1991. Rom J Gastroenterol 1991;Suppl 1, pag.49 Page 8 / 14 - Curriculum vitae of

9 8.Mircea PA, Galatar N, Duma M, Dosan L, Olinic D, Valean S, Vlaicu R. Echoguided fine-needle histological biopsy in the diagnosis of abdominal tumors. Al VI-lea Congres National de Gastroenterologie si I-ul Congres National de Endoscopie, Bucuresti 1991. Rom J Gastroenterol 1991, Suppl 1, pag.50 9.Malide D, Valean S, Petrescu M, Vlaicu R. Immunohistochemical expression of carcinoembryonic antigen in benign and malignant gastric lesions. Al VI-lea Congres National de Gastroenterologie si I-ul Congres National de Endoscopie, Bucuresti 1991. Rom J Gastroenterol 1991, Suppl 1, pag.33 10.Mircea P, Valean S, Jecan M, Olinic N. Ecografia in colestaza extrahepatica determinata de tumori pancreatice. Simpozionul de Gastroenterologie si Endoscopie, Iasi 1992. Vol.Rez. pag.40 11.Mircea P,Galatar N, Duma M, Valean S, Olinic N, Benatre A. Echoguided fine-needle biopsy in the diagnosis of abdominal tumors. Histological versus immunohistochemical studies. Simpozionul de Gastroenterologie si Endoscopie, Iasi 1992. Vol.Rez. pag.31 12.Milas D, Bolosiu HD, Valean S, Olinic N. Depistarea endoscopica a polipilor recto-colonici. Simpozionul National de Gastroenterologie si Endoscopie, Cluj, 1993. Vol.Rez.pag. 35 (poster C10) 13.Milas D, Bolosiu HD, Valean S, Olinic N, Gombosiu C, Ionescu C, Costin I, Gurzau E. Nivelul seric al unor oligoelemente in leziuni precanceroase si cancere digestive. Simpozionul National de Gastroenterologie si Endoscopie, Cluj, 1993. Vol.Rez.pag. 11 (poster E5) 14.Mircea P, Galatar N, Duma M, Valean S, Olinic N, Benatre A. Biopsia ecoghidata cu ac fin in diagnosticul tumorilor abdominale. Studiu comparativ histopatologic si imunohistochimic (date preliminare). Rom J Gastroenterol 1993, 2, Suppl 2, 60 (poster H21) 15.Mircea P, Valean S, Lucacs MC, Deacu L, Olinic N. Particularitati clinice in litiaza veziculara, in relatie cu caracterele ecografice ale calculilor veziculari. Zilele UMF Cluj-Napoca 1994. Vol.Rez.pag.129 16.Mircea P, Pop S, Valean S, Baraian I, Kerekes T, Olinic N. Factori care influenteaza performanta si complicatiile biopsiei ecoghidate a tumorilor abdominale. Zilele UMF Cluj-Napoca, 1995. Vol.Rez 17.Milas D, Pascu O, Tantau M, Valean S, Bolosiu HD. Endoscopic study of colonic polyps, clinical, epidemiological and histological correlations. Al VII-lea Congres National de Gastroenterologie si al II-lea Congres National de Endoscopie Digestiva, Bucuresti 1995. Vol.Rez. 18.Mircea P, Valean S. Chistul coledocian diagnostic si urmarire post-operatorie prin US. Zilele UMF 1996. Vol.Rez.pag. 19.Mircea P, Valean S, Pop S, Kerekes T, Chira R, Olinic N. Factori de performanta si risc in biopsia ecoghidata a tumorilor abdominale. Simpozionul National de Gastroenterologie si Endoscopie Digestiva, Targu Mures, 1997. Romanian Journal of Gastroenterology 1997, 6, Suppl.1, pag.80 20.Mircea P, Valean S, Pop S, Dudea S, Chira R, Olinic N. Pseudotumori hepatice diagnostic ecografic si prin biopsie ecoghidata. Simpozionul National de Gastroenterologie si Endoscopie Digestiva, Targu Mures, 1997. Romanian Journal of Gastroenterology 1997, 6, Suppl.1, pag.75 21.Mircea PA, Valean S, Chira R, Antonescu M, Pop S, Petrescu M. Biopsia ecoghidata a tumorilor abdominale. Factori de performanta si risc. Prima Conferinta Nationala de Ultrasonografie, Cluj 1998. Vol.Rez.pag.59-60 22.Mircea PA, Valean S, Chira R, Onea D, Suteu M. Aspecte ultrasonografice in afectarea duodenala din pancreatitele cronice. Prima Conferinta Nationala de Ultrasonografie, Cluj 1998. Vol.Rez.pag.63-64 23.Pop S, Mircea PA, Chira R, Valean S, Olinic N. Modificari ale parametrilor doppler in obstructia urinara acuta (date preliminare). Prima Conferinta Nationala de Ultrasonografie, Cluj 1998. Vol.Rez.pag.72 24.Milas D, Murza L, Valean S, Catinean A, Mircea P. Modificarile endoscopice si histologice ale mucoasei gastrice dupa tratamentul cronic cu inflamatoare nesteroidiene relatia cu Helicobacter pylori. Romanian Journal of Gastroenterology 2004, 13, Suppl.1, pag.64 (poster PO13) 25.Milas D, Murza L, Catinean A, Valean S, Mircea P. Infectia cu Helicobacter pylori la bolnavii cu polipi gastrici si duodenali. Romanian Journal of Gastroenterology 2004, 13, Suppl.1, pag.65 (poster PO14) 26.Catinean A, Mircea PA, Valean S, Chira R. Interpretarea integrativa a rezultatelor ph-metriei, manometriei si endoscopiei digestive in patologia esofagiana de reflux. Romanian Journal of Gastroenterology 2004, 13, Suppl.1, pag.95 (poster PO48) 27. Catinean A, Milas D, Valean S. Tratamentul endoscopic prin dilatare pneumatica a stenozei piloro-bulbare post-ulceroase. Al 28-lea Simopozion National de gastroenterologie, Hepatologie si Endoscopie Digestiva, Sibiu, 2007. Journal of Gastrointestinal and Liver diseases 2007;16(Suppl 1):pag. 34 (sesiunea video, prezentarea orala 11). ISI 28.Nagy G, Gordan M, Crisan D, Valean S, Vlaicu A, Mircea PA. Evaluarea non-invaziva a steatozei hepatice prin analiza computerizata a imaginilor ultrasonografice.. Al 28-lea Simopozion National de gastroenterologie, Hepatologie si Endoscopie Digestiva, Sibiu, 2007. Journal of Gastrointestinal and Liver diseases 2007;16(Suppl 1):pag. 78 (prezentarea poster H.44). ISI 29.Manzat R, Mircea PA, Valean S, Bintintan A, Martura S. Seroconversia in sistemul HbeAg/Ac si HbsAg/Ac la pacientii cu hepatita cronica virala B depistata in copilarie. Al 29-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva, Cluj-Napoca, 2009. Rezumate. Journal of Gastrointestinal and Liver Diseases 2009;18(Suppl 1):pag. 12 ( prezentare poster G55). ISI IF = 1,265 30. Martura S, Mircea PA, Muresan A, Daicoviciu D, Suciu S, Crisan D, Valean S. Implicarea stresului oxidativ in patologia ulceroasa indusa de aspirina la sobolani.. Al 29-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva, Cluj-Napoca, 2009. Rezumate. Journal of Gastrointestinal and Liver Diseases 2009;18(Suppl 1):pag. 39 ( prezentare poster O16). ISI IF = 1,265 Page 9 / 14 - Curriculum vitae of

10 31.Bintintan A, Chira R, Bintintan V, Scurtu R, Valean S, Ciuce C, Mircea PA. Tumora pancreatica pseudopapilara varietate histologica rara. Al 29-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva, Cluj-Napoca, 2009. Rezumate. Journal of Gastrointestinal and Liver Diseases 2009;18(Suppl 1):pag. 105 ( prezentare poster BP.14). ISI IF = 1,265 32.Sporea I,...Valean S...Crohn disease frequency in Romania in 2009 a multicentric study. Al XXX-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva, Craiova, 2010. Journal of Gastrointestinal and Liver diseases 2010;19(Suppl 1):pag. 104 (G60). ISI IF = 1,434 33.Sporea I...Valean S... The performance of colonoscopy in Romania in 2009 a multicentric study. Al XXX-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva, Craiova, 2010. Journal of Gastrointestinal and Liver diseases 2010;19(Suppl 1):pag. 129 (E16). ISI IF = 1,434 34. Manzat-Saplacan R, Lupsor M, Mircea PA, Valean S, Miu N, Burac L, Valean C, Nanulescu M. Assessment of liver fibrosis by using unidimensional transient elastography in patients diagnosed with chronic hepatitis B in childhood. Al XXX-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva, Craiova, 2010. Journal of Gastrointestinal and Liver diseases 2010;19(Suppl 1):pag. 129 (E16). ISI IF = 1,434 35. Sporea I,...Valean S...The practice of colonoscopy in Romania in 2011 and 2012 a multicentric study.. Al XXXIII-lea Congres National de Gastroenterologie si Hepatologie, Timisoara, 2013. Journal of Gastrointestinal and Liver Diseases 2013;22(suppl.1):pag 141 (poster presentation PP155). ISI IF= 1,849 36.Munteanu M, Valean S, Brumboiu A, Elec F, Vladutiu D, Mircea PA. Al XXXIII-lea Congres National de Gastroenterologie si Hepatologie, Timisoara, 2013. Journal of Gastrointestinal and Liver Diseases 2013;22(suppl.1):pag 149 (poster presentation PP170). ISI IF= 1,849 37. Nagy G, Alexandru R, Valean S. Frequency and anatomo-clinical spectrum of autoimmune hepatitis in a gastroenterology center (a retrospective study 2012-2015). Al XXXVI-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Cluj-Napoca, 2016. Journal of Gastrointestinal and Liver diseases 2016;25(suppl 2): pag.16 (OP 18). IF=1,891 38.Ciobanu L, Parau A, Valean S, Tantau M, Taulescu M. Effects of Rifaximin on 5-fluorouracil-induced mucositis an experimental rat model. Al XXXVI-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Cluj-Napoca, 2016.Journal of Gastrointestinal and Liver diseases 2016;25(suppl 2): pag.34 (OP 44). IF=1,891 39.Munteanu MA, Nagy G, Valean S, Gordan M, Mircea PA. Serological and clinical risk factors associated with the development and progression of non-alcoholic fatty liver and metabolic syndrome. Al XXXVI-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Cluj- Napoca, 2016.Journal of Gastrointestinal and Liver diseases 2016;25(suppl 2): pag.48 (OP 64). IF=1,891 40. Munteanu MA, Nagy G, Valean S, Gordan M, Mircea PA. The combination of non-alcoholic fatty liver disease, metabolic syndrome and atherosclerosis development, from the perspective of clinical, serological and imaging factors. Al XXXVI-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Cluj-Napoca, 2016.Journal of Gastrointestinal and Liver diseases 2016;25(suppl 2): pag.231 (V.241). IF=1,891 41.Chira RI, Hotea I, Crisan D, Valean S, Mircea PA. Eosinophilic enterocolitis a rare type of hypereosinophilic disorder. Al XXXVI-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Cluj-Napoca, 2016.Journal of Gastrointestinal and Liver diseases 2016;25(suppl 2): pag.271 (VI.299). IF=1,891 Lucrări ştiinţifice publicate in rezumat, în strainatate (selecții): prim autor -9 1.Valean S, Puscas I, Voicu L, Buzas G. Calcium-Magnesium antagonism and gastric acid secretion in humans. World Congress of Gastroenterology, Stockholm 1982. Scand J Gastroenterol 1982;17(suppl.78): pag.274 (Abstract no. 1088)( IF=2.361 in 2014) 2.Valean S, Vlaicu R, Ionescu NG. Le traitement de l ulcere gastrique avec inhibiteurs enzymatiques. Suivi endoscopique. The XIX-th International Congress SMIER, Nancy, France, 1983. Vol.Rez.pag.131 3.Valean S. Malide D, Petrescu M, Vlaicu R. Immunohistochemical expression of CEA in benign and malignant gastric lesions. EFFIS, Helsinki, 1992. Vol.Rez. 4.Valean S, Mircea P, Vlaicu R. Trends of gastric cancer mortality in Romania and Cluj county, 1955-1995. World Congress of Gastroenterology, Viena 1998. Digestion 1998;59 (Suppl 3):pag.262 (Abstract no 2208). IF = 0,824 (1998) (IF=1,832 in 2014) 5.Valean S, Tantau M, Lariu A, Petrescu M, Olinici CD, Ban A, Pop S, Chira R, Mircea P. Time trend of peptic ulcer diagnosis as compared to gastric carcinoma and chronic gastritis in an endoscopic population. 8th United European Gastroenterology Week, Brussels, 2000. Vol.Rez. 6.Valean S, Cucuianu A, Cristea A, Petrescu M. Liver cirrhosis and multiple myeloma: two case reports. 9th United European Gastroenterology Week, Amsterdam, 2001. Vol.Rez. (poster abstract) 7.Valean S, Pascu O, Tantau M, Draghici A, Sampelean D, Milas D, Pop T, Stoica L, Csakany I, Cretu L, Mircea P. Time trends of peptic ulcer and gastric cancer diagnosis in an endoscopic population. 9th United European Gastroenterology Week, Amsterdam, 2001. Vol.Rez.(poster abstract) 8.Valean S, Popescu D, Catinean A, Funariu G, Mircea P. Upper gastrointestinal bleeding (UGIB): frequency, etiology and clinical outcome in 1999 as compared to 1990. 9th United European Gastroenterology Week, Amsterdam, 2001. Vol.Rez.(abstract, S26/1654, oral presentation) 9.Valean S, Petrescu M, Catinean A, Chira R, Mircea P. Helicobacter pylori infection in patients with peptic ulcer disease complicated by Forrest III ulcer bleeding as compared to uncomplicated ulcer. 10th UEGW Geneva, 2002, Abstract issue. GUT 2002;51(Suppl.III) a215 (TUE-G-489). IF = 6,323 Lucrări ştiinţifice publicate in rezumat, în strainatate (selecții): co-autor -11 Page 10 / 14 - Curriculum vitae of

11 1.Puscas I, Buzas G, Valean S. Treatment of gastric and duodenal ulcer with carbonic anhydrase inhibitors. World Congress of Gastroenterology, Stockholm 1982. Scand J Gastroenterol 1982;17(suppl.78)(IF=2.361 in 2014) 2.Voicu L, Veres S, Pascu O, Banciu T, Valean S. La guerison des ulceres gastro-duodenauz avec les inhibiteurs de l anhydrase carbonique etude multicentrique. XVIII-eme Semaine Balkanique Medicale, Istambul, 1984. Vol.Rez.pag.142 3.Contrasiu P, Dindelegan D, Valean S, Banciu T. Traitement des ulceres gastro-duodenaux resistents aux autres therapies par des inhibiteurs enzymatiques de la secretion acide. XVIII-eme Semaine Balkanique Medicale, Istambul, 1984. Vol.Rez.pag.142 4.Puscas I, Reznicek A, Milas D, Valean S. Inhibition of gastric acid secretion by a beta-adrenergic antagonist propranolol in duodenal ulcer patients. Mechanism of action. Gastroenterology 1986;5, vol.90 5.Mircea P, Iacob D, Valean C, Pop S, Valean S, Nanulescu M, Miu N, Olinic N. Ultrasound diagnosis and postoperative follow-up of the choledochal cyst. Congres Euroson, 1996, Budapest. Vol.Rez. 6.Bacq Y, Trafforeau V, Valean S, Dubois F, Goudeau A. Reevaluation des facteurs de risque associes a la seropositivite pour le virus de l hepatite C. Etude prospective de 383 personnes examinees consecutivement en consultation d hepatologie de 1990 a 1995. Gastroenterol. Clin. Biol 1996;20:798 7.Tantau M, Badea R, Sparchez Z, Mircea P, Valean S, Pascu O. Endoscopic treatment of chronic pancreatitis. First Romanian experience. World Congress of Gastroenterology, Viena 1998. Digestion 1998;59 (Suppl 3):pag.500 (Abstract FoLM3466). IF = 0,824 (1998) (IF=1,832 in 2014) 8.Mircea P, Valean S, Chira R, Onea D, Suteu M, Olinic N. Ultrasonographic appearance of the duodenum in chronic pancreatitis. The 9th Congress of World Federation for Ultraound in Medicine and Biology. Florence, Italy, 2000. Vol.Rez. vol 26 (suppl 2):IPO53/A154 9. Mânzat Săplăcan R, Lupsor M, Mircea PA, Valean S, Miu N, Burac L, Valean C, Nanulescu M. Assessement of the regression of fibrosis by using unidimensional transient elastography in patients diagnosed with chronic hepatitis B in childhood. 18 th UEGW Barcelona, 2010, Abstract Issue. Gut 2010;59 (Suppl III) A 431 (P1608). IF = 10,614 (2010) 10. Nagy G, Gordan M, Mircea PA, Valean S,... A reduced computational complexity method in non-invasive evaluation of hepatic fibrosis by ultrasound image analysis and support vector machine. 18 th UEGW Barcelona, 2010, Abstract Issue. Gut 2010;59 (Suppl III) A 10 (OP046). IF = 10,614 (2010) 11. Nagy G, Munteanu M, Valean S, Iancu M, Crisan D, Mircea P. Hepatic steatosis and viral hepatitis B and C: role of metabolic syndrome.the 49 th Annual Scientific Meeting of the European Society for Clinical Investigation, Cluj-Napoca, Romania, 27-30 May, 2015. Abstract book. European Journal of Clinical Investigation 2-15;45(suppl.2): pag. 16 (2.08) Citări de către alţi autori : 17 (Romani: 7, Straini: 10) 1. Koelz HR, Fimmel CJ, Garner A, et al. The stomach and duodenum. In: Kern F, Blum AL eds. The Gastroenterology Annual 3. Elsevier Science Publishers B.V. 1986 (ref 404). (Articol citat 1.Vălean S, Vlaicu R, Ionescu I. Treatment of gastric ulcer with carbonic anhydrase inhibitors. Annals of the New York Academy of Science, vol 429, Biology and Biochemistry of the Carbonic Anhydrases. Ann N Y Acad Sci.1984;429:597-600 2. Chira Constantin et al. Cancerul gastric. In : TRATAT DE GASTROENTEROLOGIE. M Grigorescu (ed). Ed. Medicală Naţională, Bucureşti, 2001 (ref. 8) (Articol citat 6. Simona Vălean, Magda Petrescu, CD Olinici, A Ban, E Dumitru, R Buiga, O Pascu, PA Mircea, R Vlaicu. Incidenta cancerului gastric in 1995 comparativ cu 1985 in Cluj. Aspecte anatomo-clinice. Jurnalul Român de Patologie 1999;3(1): 91-8 3. Simona Tache. Functia hematopoietica. Biosinteza hemului, excretia porfirinelor. In: A Muresan, S Tache, M Acalovschi, M Grigorescu. Fiziologia ficatului. In: TRATAT DE HEPATOLOGIE. M Grigorescu (ed). Ed. Medicală Naţională, Bucureşti, 2004 (ref. 72) (Capitol citat din 4. TRATAT DE GASTROENTEROLOGIE CLINICA (sub red. M Grigorescu, O Pascu). Ed. Tehnică, Bucureşti, vol. II 1997 (capitol redactat : Porfiriile pag.479-495) 4. Marcus EA, Moshfegh AP, Sachs G, Scott DR. The Periplasmatic α-carbonic Anhydrase Activity of Helicobacter pylori is Essential for Acid Acclimation. J Bacteriol. 2005;187(2):729-738 (ref. 41) (Articol citat 1.Vălean S, Vlaicu R, Ionescu I. Treatment of gastric ulcer with carbonic anhydrase inhibitors. Annals of the New York Academy of Science, vol 429, Biology and Biochemistry of the Carbonic Anhydrases. Ann N Y Acad Sci.1984;429:597-600 5.Rainhard Fuhr (Parexel International Corp). Gastrointestinale Nebenwirkungen von Antibiotika. Der Gastroenterologie, september 2006. (Articol citat 10. Simona Vălean, Magda Petrescu, A Catinean, R Chira, PA Mircea. Pill esophagitis. Rom J Gastroenterol 2005; 14(2): 159-63 6.Pap Z, Pavai Z, Denes L, Kovalszky I, Jung J. An immunohistochemical study of colon adenomas and carcinomas: E-cadherin, Syndecan-1, Ets- 1. Pathol. Oncol. Res. 2009;15:579-87 (ref.1) (Articol citat 13. Simona Valean, et al. Cancer mortality in Romania, 1955-2004. Digestive sites: esophagus, stomach, colon and rectum, pancreas, liver, gallblader and biliary tree. J Gastrointestin Liver Dis 2008;17(1): 9-14 7.Cardinale V, Semeraro R, Torrice A, et al. Intra-hepatic and extra-hepatic cholangiocarcinoma: new insight into epidemiology and risk factors. World J Gastrointest Oncol 2010 2(11):407-16 (ref. 27) (Articol citat 13. Simona Valean, et al. Cancer mortality in Romania, 1955-2004. Digestive sites: esophagus, stomach, colon and rectum, pancreas, liver, gallblader and biliary tree. J Gastrointestin Liver Dis 2008;17(1): 9-14 8. Mates IN, Csiki I, Mates D, et al. Association of common genetic variants with colorectal cancer risk in a Romanian sample. Chirurgia 2010;105:749-57 (ref. 4) (Articol citat 13. Simona Valean, et al. Cancer mortality in Romania, 1955-2004. Digestive sites: esophagus, stomach, colon and rectum, pancreas, liver, gallblader and biliary tree. J Gastrointestin Liver Dis 2008;17(1): 9-14 9. Chivu Economescu M. Identificarea si validarea unor tinte moleculare la nivelul celulelor stem tumorale gastrice pentru dezvoltarea unor strategii terapeutice antitumorale. Proiect UEFISCSU TE-100/2010, 2010-2013, coordonator Inst. De Virusologie Stefan Nicolau, director proiect Dr. Mihaela Chivu Econoomescu (Motivatie proiect, (ref. 14) (Articol citat 13. Simona Valean, et al. Cancer mortality in Romania, 1955-2004. Digestive sites: esophagus, stomach, colon and rectum, pancreas, liver, gallblader and biliary tree. J Gastrointestin Liver Dis 2008;17(1): 9-14 Page 11 / 14 - Curriculum vitae of