The PlantLIBRA Plant Food Supplement Consumer Survey The first European survey of Plant Food Supplement users

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The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 The first European survey of Plant Food Supplement users

SUMMARY Key findings This survey has been conducted in 2359 plant food supplements (PFS) consumers, males and females, aged 18-59 and 60+ years and has evaluated a total of 1288 reported PFS from over 400 manufacturers. A total of 491 different botanical ingredients have been identified in the consumed PFS. In all countries, most consumers take 1 product. Finland is the country that has more consumers of more than 1 product. More than half of all the products reported contain 1 botanical only. Multi-botanical products are more popular in Finland (with 38.2% of products). The most common dose forms were capsules and pills/tablets/lozenges. Overall, the most consumed botanicals (as ingredients of PFS) are ginkgo (Ginkgo biloba), aloe (Aloe vera), artichoke (Cynara scolymus), ginseng (Panax ginseng) and valerian (Valeriana officinalis), all reported, as the most consumed, in at least two countries. The most commonly used botanicals differ across countries. Only 3.7% of the interviewed PFS consumers reported having experienced any adverse effect. The most popular place of purchase-in all countries except for Romania- is the health/herbal shop followed by the pharmacy. The most reported source of recommendation by PFS users -in all countries except for Italy- is the word of mouth (friend/relative). In 4 out 6 countries most consumers take these products periodically. The United Kingdom and Finland are the countries with more all-year-round PFS users. At least 50% of PFS users report that the product always helps them. Achievements and conclusions The PlantLIBRA Consumer Survey is the first to report on the usage of botanicals by PFS consumers in six European countries. The survey highlights how complex it is to measure the intake of such products, particularly at European level. This survey provides us with a much clearer understanding of consumer behavior, we now know more about the products consumers are taking and how they are taking them. Having consumption data for these products will help assess the risks and benefits of PFS and their botanical ingredients, which in turn will facilitate the decision-making by regulators and the industry. Our work can be used by other groups who want to contribute to the pool of knowledge in this field". Further information is needed. Future national dietary surveys within Europe should collect data on the intake of botanicals in order to facilitate the assessment of the risks and benefits associated with these products. The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 1

WHAT IS THE PlantLIBRA PLANT FOOD SUPPLEMENT CONSUMER SURVEY? The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 2 Conducted by six partners of the EU Project PlantLIBRA (www.plantlibra.eu) in their respective six different countries, the PlantLIBRA Plant Food Supplements (PFS) Consumer Survey has collected data on usage from PFS consumers in six European countries. These data were collected through personal interviews during the 15 months from May 2011 to August 2012. Survey results have provided data to evaluate: the products consumed and their botanical ingredients the usage patterns of PFS products the socio-demographic profile of PFS users These results will contribute to achieving the objectives of the PlantLIBRA Project on riskbenefit and safety assessment of PFS and inform the future regulation of the sector by the European Commission. WHAT ARE PLANT FOOD SUPPLEMENTS (PFS)? PFS are defined as "foodstuffs the purpose of which is to supplement the normal diet and which are concentrated sources of botanical preparations that have nutritional or physiological effect, alone or in combination with vitamins, minerals and other substances which are not plant-based. PFS are marketed in dose form, such as capsules, pastilles, tablets, pills and other similar forms, sachets of powder, ampoules of liquids, drop dispensing bottles, and other similar forms of liquids and powders designed to be taken in measured small unit quantities. WHO WAS ELIGIBLE TO PARTICIPATE IN THE SURVEY? DEFINITION OF THE PFS CONSUMER Eligible participants were individuals aged between 18-59 years or 60+, who in the preceding 12 months had been regular PFS consumers and who met strict selection criteria for usage of PFS.

SURVEY SAMPLE PROFILE AND SIZE The PlantLIBRA PFS Consumer Survey was conducted in 24 cities in six European countries, namely Finland, Germany, Italy, Romania, Spain and the United Kingdom, with an approximate sample size of 400 adult and elderly consumers per country (approximately 2400 in total). Cádiz Las Palmas de Gran Canaria Glasgow Berlin Swansea London Frankfurt Soria LeicesterHamburg Milano Barcelona München Roma Catania Kuopio Countries and cities participating in the PlantLIBRA Consumer Survey SURVEY CONTENT UNITED KINGDOM SPAIN FINLAND A 5-minute questionnaire was used initially to identify consumers of PFS in the previous 12 months. Those considered eligible consumers who were also willing to participate completed a 30-minute questionnaire during an interview about their PFS usage. This questionnaire consisted of 58 questions, 20 of which asked about aspects of PFS usage, and 38 asked about socio-demographic, health and lifestyle aspects. Oulu Turku Helsinki GERMANY Iasi Cluj Napoca Timisoara Bucharest Venezia ITALY ROMANIA The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 3

The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 4 Key finding 1 This survey has been conducted in 2359 PFS consumers, males and females aged 18-59 and 60+ years. Across all countries, more than half of the participants (57.5%) were employed. The majority of participating consumers were educated to medium level Socio-demographic characteristics of the consumer sample, overall and by country. Consumer characteristics All countries Finland Germany Italy Romania Spain United Kingdom a. Other groups: Unemployed; Housework; Student; Retired; Disabled; and Other. % % % % % % % Gender Male 48.4 48.1 49.5 49.5 49.8 43.3 50.3 Female 51.6 51.9 50.5 50.5 50.3 56.7 49.7 Age 18-29 years 17.7 15.7 19.4 22.2 30.5 9.5 9.0 30-39 years 18.9 16.2 14.3 23.3 16.3 25.1 18.2 40-49 years 19.5 16.0 20.6 16.7 11.5 21.9 30.8 50-59 years 18.7 26.2 20.1 13.0 16.8 18.9 16.8 60 years 25.2 25.9 25.6 24.9 25.0 24.6 25.3 Education Low 10.6 11.7 0.8 19.1 8.8 22.9 - Medium 65.7 59.1 82.7 58.7 47.5 63.7 82.9 High 23.8 29.2 16.6 22.2 43.8 13.4 17.1 Current employment status Employed 57.5 50.9 60.3 58.5 62.3 60.7 52.4 Other groups a 42.5 49.1 39.7 41.5 37.8 39.3 47.6

1400 1200 1000 800 600 400 200 0 1288* Key finding 2 A total of 1288 reported PFS from over 400 manufacturers have been evaluated, containing a total of 491 different reported botanicals Reported characteristics of consumed PFS, by country 491** 289 284 213 190 196 196 222 191 219 218 116 47 Number of products Number of botanicals Number of manufacturers Total Finland Germany Italy Romania Spain United Kingdom *Products and manufacturers have not been compared between countries due to language differences, so their totals refers to the sum of products or manufacturers from the six countries, prior to comparison and therefore elimination of the duplicates that may exist. **The total number of botanicals is indeed the final figure, as botanical scientific names were used (in Latin) and duplicates were eliminated. 449* 69 99 106 61 97 17 The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 5

The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 6 Distributions of the consumers (%) according to the number of products they consume, per country Finland (n=401) Germany (n=398) Italy (n=378) Romania (n=400) Spain (n=402) United Kingdom (n=380) Key finding 3 In all countries, most consumers take one product. Finland has more consumers reporting more than one product as compared to the other countries 1 product 2 products >2 products 59.9 88.2 90.2 87.5 85.8 91.6 23.2 17.0 11.3 9.0 10.0 11.9 0% 20% 40% 60% 80% 100% 7.6 0.5 0.8 2.5 2.2 0.8

Characteristics of consumed products (%) according to the number of botanicals they contain 8.0 7.9 16.3 Key finding 4 More than half of all the products reported contain 1 botanical only 10.6 57.3 1 Botanical 2 Botanicals 3 Botanicals 4-5 Botanicals >5 Botanicals The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 7

The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 8 90 80 70 60 50 40 30 20 10 0 52 21 63 Type of products taken (%), by country 85 53 47 43 45 44 39 32 1 single-botanical 1 multi -botanical 2 or more singlebotanical 25 33 7 4 Product type 2 3 3 5 7 7 12 38 9 6 2 or more single- and multi-botanical Total (n=2359) Finland (n=401) Germany (n=398) Italy (n=378) Romania (n=400) Spain (n=402) United Kingdom (n=380) Key finding 5 Multi-botanical products are popular in Finland (with 38.2% of products) 8 8 2

PFS dose forms (%), per product used by a respondent, by country Finland (n=665) Germany (n=446) Italy (n=417) Romania (n=464) Spain (n=465) United Kingdom (n=417) Key finding 6 The most consumed dose forms are capsules and pills/tablets/lozenges Capsules Pills/tablets/lozenges Liquid Ampoules Other 17.7 31.0 34.5 50.5 53.8 46.5 50.4 39.3 30.2 34.5 21.1 44.1 26.4 17.7 26.2 14.8 9.9 3.1 10.1 9.5 8.2 0 10 20 30 40 50 60 70 80 90 100 3.6 5.2 5.8 4.1 0.9 1.2 The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 9

United Kingdom (n=380) Spain (n=402) Romania (n=400) Italy (n=378) Germany (n=398) Finland (n=401) The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 10 Consumer distribution of the three most used PFS-contained botanicals (%), per country Glycine max Echinacea angustifolia Echinacea purpurea Ginkgo biloba Cynara scolymus Olea europaea Aloe vera Foeniculum vulgare ssp. Valeriana officinalis Ginkgo biloba Aloe vera Panax ginseng Cynara scolymus Valeriana officinalis Equisetum arvense Oenothera biennis Panax ginseng Hypericum perforatum Key finding 7 Overall, the most consumed botanicals (as ingredients of PFS) are ginkgo (Ginkgo biloba), aloe (Aloe vera), artichoke (Cynara scolymus), ginseng (Panax ginseng) and valerian (Valeriana officinalis), all reported in at least two countries. The most commonly used botanicals differ across countries 7.7 7.7 10.1 10.3 10.0 9.2 11.8 11.6 11.8 10.8 13.7 13.7 12.6 12.7 18.2 16.7 26.3 43.2 0 5 10 15 20 25 30 35 40 45 50

Reported adverse effects (% of the total) 3.7 Key finding 8 Only 3.7% of the interviewed PFS consumers reported having experienced any adverse effect 96.3 No adverse effects reported Adverse effects reported The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 11

The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 12 Key finding 9 The most popular place of purchase -in all countries except for Romania- is the health/herbal shop, followed by the pharmacy Places of purchase, by country Total Finland Germany Italy Romania Spain United Kingdom % % % % % % % Health/herbal shop 54.8 54.8 50.4 64.4 43.1 70.9 44.3 Pharmacy 27.9 15.4 31.2 23.3 49.8 16.2 38.1 Supermarket/grocery store 14.0 24.5 6.2 8.3 1.3 21.5 17.3 Internet 7.1 6.6 25.0 3.1 1.5 4.0 1.9 Not sure 7.0 0.8 13.5 1.2 18.8 4.6 5.3 Network marketing 5.6 9.7 3.3 2.4 7.1 1.9 7.5 Gym 1.3 0.8 0.2 1.2 0.0 0.4 6.0 Mail order (manufacturer/distributor) 1.1 4.7 0.0 0.0 0.0 0.0 0.0 Friends/relatives 1.0 2.1 1.1 1.4 0.0 0.8 0.2 Telemarketing 0.2 0.9 0.0 0.0 0.0 0.0 0.0

Key finding 10 The most reported source of recommendation by PFS users -in all countries except Italy- is the word of mouth (friend/relative) Ten most reported sources of recommendation of PFS consumption, by country Total Finland Germany Italy Romania Spain United Kingdom % % % % % % % Friend/relative 38.2 41.1 44.9 30.7 39.7 33.1 38.1 Nobody/myself 23.2 42.7 22.3 15.6 16.4 14.3 18.3 Herbal shop assistant 15.6 17.2 6.2 34.2 10.3 15.2 10.4 Doctor/General Physician 10.7 4.7 12.2 12.3 22.6 9.7 4.6 Pharmacist 10.0 2.9 20.1 12.7 18.5 6.9 1.4 Nutritionist/dietitian 8.2 2.7 2.0 1.4 4.1 20.4 21.0 Magazine/newspaper 8.1 18.0 10.4 1.7 6.0 0.4 7.5 Internet/social group 6.5 7.9 12.2 3.1 6.5 4.0 4.8 Homeopath 5.1 2.3 10.2 3.3 2.6 9.3 4.1 TV/radio 2.2 3.8 3.1 0.9 3.0 1.1 0.2 The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 13

The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 14 PFS usage patterns (%), per product used by a respondent, by country 60 50 40 30 20 10 0 20 13 23 18 13 23 35 I took it whenever/sporadically 37 46 51 4142 I take it periodically, during those times only 31 25 25 25 22 19 20 16 15 I took it when I had a flare up/worsening of condition 21 18 6 8 11 46 Other reason Total (n=2874) Finland (n=665) Germany (n=446) Italy (n=417) Romania (n=464) Spain (n=465) United Kingdom (n=417) Key finding 11 In 4 out 6 countries most consumers take these products periodically 12 3 1 1 3 9 Not sure 1 4

Distribution of consumers that have taken PFS all year round (%), by country 60 50 40 30 20 10 0 48.5 19.8 Key finding 12 The United Kingdom and Finland are the countries with the most all-year-round PFS users 12.4 16.8 27.1 56.3 Finland Germany Italy Romania Spain United Kingdom The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 15

The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 16 Key finding 13 At least 50% of PFS users report that the product always helps them Level of confidence: Do you think the product helps you?, by country 90 80 79 70 68 64 60 56 56 53 50 44 40 38 30 31 31 27 30 20 20 16 9 9 8 9 10 3 5 6 4 6 7 1 4 1 4 2 3 0.4 0.5 1 1 0 5 Not at all Rarely Sometimes Always Not sure Total Finland Germany Italy Romania Spain United Kingdom

CONFIDENTIALITY All data collected in this survey are used for statistical purposes only and interviews were conducted by a market research organization (European Fieldwork Group) in strict accordance with the ICC/ESOMAR Code on Market and Social Research, and therefore, are guaranteed by law to be held in the strictest of confidence. FUTURE USES OF PlantLIBRA PFS CONSUMER SURVEY DATA Can be used by Policymakers PFS industry Consumers Academics Other researchers Health professionals Can be used to Provide PFS usage data at EU level (six countries) in order to: Provide data on the nature and frequency of PFS usage Obtain a socio-demographic and lifestyle-related profile of the PFS consumer Identify the most frequently used botanical ingredients in these PFS products Highlight the issues associated with measuring usage of PFS in European populations and make recommendations for future research Provide PFS usage data for risk-benefit and safety assessment of PFS consumption, in order to: Provide consumers with more information to help them make more conscious decisions about their PFS use Provide health professionals with knowledge to advise patients/consumers Provide policymakers with more information for regulation of the sector The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 17

PlantLIBRA PFS CONSUMER SURVEY DATA DISSEMINATION AND ACCESS The PlantLIBRA Plant Food Supplement Consumer Survey 2011-2012 Page 18 PlantLIBRA PFS Consumer Survey team Fundación para la Investigación Nutricional (FIN) - Spain (leader and coordinator) Elintarviketurvallisuusvirasto (EVIRA) - Finland Phytolab GmbH - Finzelberg (PLFIN) - Germany Università degli Studi di Milano (UMIL) - Italy Universitatea Transilvania din Brasov (UTBV) - Romania University of Surrey (UNIS) - United Kingdom Brochure s production team Content Fundación para la Investigación Nutricional (FIN-coordinator), CIBER Fisiopatología de la Obesidad y Nutrición, Instituto Carlos III (CIBER OBN), and University of Las Palmas de Gran Canaria (ULPGC) - Spain Elintarviketurvallisuusvirasto (EVIRA) - Finland Phytolab GmbH - Finzelberg (PLFIN) - Germany Università degli Studi di Milano (UMIL) - Italy Universitatea Transilvania din Brasov (UTBV) - Romania University of Surrey (UNIS) - United Kingdom Design & dissemination Società italiana di scienze applicate alle piante officinali ed ai prodotti per la salute (SISTE) - Italy Further information Visit the PlantLIBRA Project website www.plantlibra.eu PFS use in 6 EU countries This project has received funds from the European Union s Seventh Framework Programme for research, technological development and demonstration under grant agreement n [245199] This report does not necessarily reflect the Commission's views or its future policy on these areas.