ORYZA SQUALANE CATALOG ver. 2.0TS

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ORYZA SQUALANE Cosmetic Agents for Moisturizing Rice has been widely grown in the Southeast Asia, not only as a chief crop but also as acts an integral part of traditional culture and lifestyle of some Asian countries. Especially, this oil has an important role, the only oil used domestic materials, has been used as foods and cosmetics. In the course of our investigation on rice bran and germ for a long time, some products were developed by containing in it, and have been used as medicines, cosmetics, health foods, and food additives. Recently, rice squalene were extracted from rice bran and rice germ, and produced by Oryza Oil & Fat Chemical Co., Ltd named as ORYZA SQUALANE. 1. Squalane Squalane, a saturated hydrocabon(c 30 H 62 ), is obtained by hydrogenation of squalene, which have been used as cosmetics for moisturizer. At present, squalane is used as cosmetics, medicines and sometimes used with fibers. Squalene, a material for squalane, is contained shark liver oil, rice, olive, soybean, and so on. Until now it was only obtained from shark liver oil, which can contain a lot of squalene than vegetable oil. However, it is well known that extensive fishing has reduced quantity of sharks in some areas and led to occasional shortages. Moreover, there is a growing concern about the environment and a higher ecological sensitivity among consumers. In addition, there are some problems, in the following, pollution in marine animals by dioxin and agricultural chemical, shark liver oil include pristane. 2

2. Structure of Squalane C30H62422.82 3. Characteristics of ORYZA SQUALANE 100 rice origin No pristane Spread well Tasteless and odorless Low volatilization Penetration well into the skin Stability well Light feel than liquid paraffin 4. Acute Toxicity and Safety Five week old mice were orally given ORYZA SQUALANE (5000 mg/kg) and then fed a laboratory chow for two weeks. No toxic effects were observed, thus the LD 50 (mouse) is more than 5000 mg/kg. 5. Practical Applications of ORYZA SQUALANE Applications Examples Cosmetics Base cosmetics(lotion, Milk, Cream, and so on) Body cosmetics(body lotion, Body cream, and so on) Cleansing cosmetics(soap, and so on) Makeup cosmetics(lipstick, Foundation, and so on) Fibers Lingerie, Stocking, and so on 3

6. Packaging Filling nitrogen 15kgCan 7. Storing Method Store in dark place, avoid heat and humidity. 4

PRODUCT STANDARD PRODUCT NAME ORYZA SQUALANE This product is squalane that be obtained by distillation and hydrogenation of squalene from rice bran oil. Quantity of squalane is more than 75.0. Appearance Certification Test Content(GC) Min. 75.0 Acid Value Max. 0.5 Saponification Value Max. 2.0 Iodine Value Max. 2.0 Gravity 20 d = 0.8080.829 20 Refractive Index 20 n = 1.4501.460 D Ignition Residue This product is colorless and odorless liquid oil. Dissolve 0.4g of this product with n-hexane in a 100 ml volumetric flask, and add n-hexane to volume(solution A). On the other hands, dissolve 0.4g of squalane with n-hexane in a 100 ml volumetric flask, and add n-hexane to volume(solution B). Analysis is performed by gas chromatography(gc). Use 1.0 l of solution A and B, retention time of A solution shows same retention time of B solution. Max. 0.10(5g) Purity Test (1) Heavy Metals Max. 10ppm (2) Nickel After 5.0g of this product is dissolved in 5 ml of diluted hydrochloric acid for 1 minute, ammonia liquid is added to the water layer to be alkalified. Then, 50 mg of lead dioxide, a drop of sodium hydroxide, and 1 ml of dimethylglyoxime solution are added to the water layer, it dose not occur red coloring. (3) Arsenic Max. 1ppm Composition Ingredients Contents Squalane from rice 100% We reterred to the experiment methods of The Japanese Standards of Cosmetic Ingredients (NOTES) This product is applicable to JCIC 42-520576. 5

ORYZA OIL & FAT CHEMICAL CO., LTD., striving for the development of the new functional food materials to promote your health. From product planning to OEM - For any additional information or assistance, please contact : ORYZA OIL & FAT CHEMICAL CO., LTD. No.1, Numata Kitagata-cho, Ichinomiya-city, Aichi-pref., 493-8001 JAPAN Tel: +81 (0) 586 86 5141 Fax: +81 (0) 586 86 6191 URL/http://www.oryza.co.jp/ E-mail : info@oryza.co.jp *The contents of this catalogue may be changed without prior notice. Established Date : May 27, 1999 Revised Date : August 17, 2002 6