Kristopher D. Marjon PO BOX 117 Palo Alto 94302 (505) 331-7115 kdmarjon@stanford.edu Education 2012 Ph.D. with Distinction in Biomedical Sciences, School of Medicine Graduate Program, University of New Mexico Health Sciences Center Dissertation: Immune Regulation and Fc(alpha)RI Recognition and Activation by C-Reactive Protein 2006 B.S. in Biochemistry, University of New Mexico Research and Professional Experience 2015 Postdoctoral Research Fellow, Institute for Stem Cell Biology and Regenerative Medicine, Stanford. Mentor: Irving Weissman M.D. 2012 Postdoctoral Research Fellow, Department of Pathology, University of New Mexico. Mentor: Jennifer M. Gillette Ph.D. 2007 Graduate Student, Department of Molecular Genetics and Microbiology, University of New Mexico. Mentor: Terry Du Clos M.D., Ph.D. 2006 Post-Baccalaureate Intern. Department of Molecular Genetics and Microbiology, University of New Mexico. Mentor: Carolyn Mold Ph.D. 2005 Undergraduate Student Researcher. Department of Molecular Genetics and Microbiology, University of New Mexico. Mentor: Carolyn Mold Ph.D. 2003 Undergraduate Student Lab Assistant. Department of Neuroscience, University of New Mexico. Mentor: John Guzowski Ph.D. Honors and Awards 2014 ASCB poster awardee (Third place), Minorities affairs committee poster awards 2014 Minorities Affairs Committee Travel Awardee to attend the 2014 Annual American Society For Cell Biology conference 2014 MBL: Frontiers in Stem Cells and Regeneration Course. Financial assistance awardee and attendee. Woods Hole, Ma.
2014 Cardiovascular and Metabolism Research Day oral presentation award 2013 Minorities Affairs Committee Travel Awardee to attend the 2013 Annual American Society For Cell Biology conference 2013 The American Society For Cell Biology Minorities Affairs Committee 8 th annual Junior Faculty and Postdoctoral Fellows Career Development Workshop travel award and attendee 2013 The New York Academy of Sciences Early-career Minority Investigator Travel Fellowship to attend The Bone Marrow Niche, Stem Cells and Leukemia: Impact of Drugs, Chemicals, and the Environment 2013 T32 Cardiovascular and Metabolic Disease Fellow, University of New Mexico 2012 Minorities Affairs Committee Travel Awardee to attend the 2012 annual American Society For Cell Biology conference 2012 Passed Doctoral Thesis Examination with Distinction 2011 Integrating Nanotechnology with Cell Biology and Neuroscience Integrative Graduate Education and Research Traineeship Fellow (INCBN IGERT) 2011 American Association of Immunologist Abstract Awardee 2011 Passed Comprehensive Examination with Honors 2009 Ruth L. Kirschstein Predoctoral National Research Service Award National Institute of Allergy and Infectious Diseases, NIH 2008 T32 Infectious Diseases and Inflammation Training Program (IDIP) Fellow 2007 NSF: Integrating Nanotechnology with Cell Biology and Neuroscience Integrative Graduate Education and Research Traineeship Fellow (INCBN IGERT) 2006 Post-Baccalaureate Research Education Program Fellow 2006 Initiative to Maximize Research Education Program Fellow 2005 Profound Research Stipend Educational Activities 2015 Summer undergraduate student research mentor (Tal Rosen)
2013 Rotating 1 st year graduate student mentor (Chelsea Saito-Reis) 2012-2013 Co-mentor undergraduate honors research scholar (César Soria) 2012 Summer student research mentor (Kathryn Sanders) 2011 Summer student research mentor (Michael Schwartz) 2010 Summer student research mentor (Julian Weisburd-Malloy) 2009 Rotating 1 st year graduate student mentor (Mitch Tyler) 2008 Rotating 1 st year graduate student mentor (Carl Bown) Oral Presentations 2015 Weissman Laboratory Scientific Retreat, Rocky Mountain Laboratories. Hamilton, MT. August. 2014 4 th Annual Cardiovascular and Metabolism Research Day. Albuquerque, NM. April. 2013 7 th International Tetraspanin Summer Research Conference. Nashville, TN. June. 2011 American Association of Immunologist. San Francisco, CA. May. 2010 FASEB Immunoreceptors. Snowmass Village, CO. July. 2007 IMSD Research Symposium. Albuquerque, NM. August. 2005 Initiative to Maximize Student Diversity (IMSD) Research Symposium. Albuquerque, NM. August. Poster Presentations Marjon KD, Termini CM, Karlen KL, Soria CE, Saito-Reis C, Sanders KE, Gillette JM. Tetraspanin CD82 regulates acute myelogenous leukemia cell homing and beta catenin signaling through the stabilization and clustering of membrane-bound proteins. Annual American Society for Cell Biology. Philadephlia, PA. December 2014. Marjon KD, Soria CE, Sanders KE, Karlen KL, Termini CM, Gillette JM. CD82 Regulates Acute Myelogenous Leukemia Cell Homing and Drug Sensitivity. Stem Cells and Myeloproliferative Disorders. Providence, RI. March 2014.
Marjon KD, Soria CE, Sanders KE, Karlen KL, Termini CM, Gillette JM. CD82 Regulates Acute Myelogenous Leukemia Cell Homing and Drug Sensitivity. 2013 Annual American Society of Cell Biology. New Orleans, LA. December 2013. Marjon KD, Soria C, Sanders KE, Termini CM, Gillette JM. Expression of CD82 Regulates the Beta Catenin Signaling Cascade. 7 th International Tetraspanin Summer Research Conference. Nashville, TN. June 2013. Marjon KD, Soria C, Sanders KE, Termini CM, Gillette JM. Expression of CD82 Promotes Hematopoietic Stem Cell Survival and Adhesion to the Microenvironment. The New York Academy of Sciences The Bone Marrow Niche, Stem Cells, and Leukemia: Impact of Drugs, Chemicals, and the Environment. New York City, NY. May 2013. Marjon KD, Sanders KE, Soria C, Termini CM, Gillette JM. The regulation of β-catenin and N-cadherin by CD82. Spatio Temporal Modeling Center: Understanding Cell Behavior through Single Cell and Single Molecule Biology. Albuquerque, NM. January 2013. Marjon KD, Sanders KE, Soria C, Termini CM, Gillette JM. The regulation of β-catenin and N-cadherin by CD82. 2012 Annual Meeting for The American Society for Cell Biology. San Francisco, CA. December 2012. Marjon KD, Lu J, Marnell L, Wang R, Mold C, Sun P, Du Clos T. Recognition and Functional activation of human FcαRI by C-reactive protein. 98 th Annual Meeting for the American Association of Immunologist. San Francisco, CA. May 2011. Marjon KD, Lu J, Marnell L, Mold C, Sun P, Du Clos T. C-Reactive Protein Binds and Induces Phagocytosis through FcαRI. FASEB Immunoreceptors. Snowmass Village, CO. July 2010. Marjon KD, Lu J, Park K, Mold C, Du Clos T, Sun P. C-reactive protein binds and binds and induces phagocytosis through FcalphaRI. American College of Rheumatology Annual meeting. Philadelphia, PA. October 2009. Marjon KD, Du Clos TW, Marnell LL, Verbeek JS, Mold C. C-reactive protein stimulated spleen cells transfer suppression of experimental immune thrombocytopenia. Abstract for poster presentation, 94 th Annual Meeting for The American Association of Immunologist. Miami, FL. May 2007. Marjon KD, Morris C, Mold C. CRP regulates cytokine response on monocytes. Abstract for poster presentation, UNM 3 rd annual PROFOUND Research Symposium Albuquerque, NM. March 2006.
Marjon KD, Mold C, Morris C, Du Clos TW. Cytokine response from CRP binding to apoptotic and necrotic cells. Abstract for poster presentation, SACNAS Annual Meeting. Denver, CO. September 2005. Professional Affiliations American Society for Cell Biology, 2012- present American Association of Immunologist, 2007- present Publications 1. Marjon KD, Termini CM, Karlen KL, Soria CE, Sanders KE, Gillette JM. CD82 Regulates Acute Myelogenous Leukemia Cell Homing. (in press) Oncogene. 2015 2. Termini CM, Cotter M, Marjon KD, Buranda, Lidke KA, Gillette JM. The membrane scaffold CD82 regulates cell adhesion by altering α4 integrin stability and molecular density. Mol Biol Cell. 15:1560-1573. 2014. 3. Lu J, Marjon KD, Mold C, Marnell L, Du Clos TW, Sun PD. Pentraxins and IgA share a binding hot-spot on FcαRI. Protein Sci. 23:378-386. 2014. 4. Marjon, K.D. and Gillette, J.M. Measurement of intercellular transfer to signaling endosomes. Methods Enzymol. 534:207-22. 2014. 5. Lu J, Marjon KD, Mold C, Du Clos TW, Sun PD. Pentraxins and Fc Receptors. Immunological Reviews. 250:230-238. 2012. 6. Lu J *, Marjon KD *, Marnell LL, Mold C, Du Clos TW, Sun PD. Recognition and functional activation of human FcαRI by C-reactive Protein. Proc Natl Acad Sci USA. 108:4974-9. 2011. * Co-first authors 7. Lu J, Marnell L, Marjon KD, Mold C, Du Clos TW, Sun PD. Structural recognition and functional activation of FcγR by innate pentraxins. Nature. 456:989-92. 2008. 8. Marjon KD, Marnell L, Mold C, Du Clos TW. Macrophage activated by C-Reactive Protein through FcγRI Transfer Suppression of Immune Thrombocytopenia. Journal of Immunology. 182:1397-13403. 2009. 9. McIntyre CK, Miyashita T, Setlow B, Marjon KD, Steward O, Guzowski JF, McGaugh JL. Memory-influencing intra-basolateral amygdala drug infusions modulate expression of Arc protein in the hippocampus. Proc Natl Acad Sci USA 102:10718-23. 2005.
Manuscripts in Preparation 1. Marjon KD, Karlen KL, Saito-Reis C, Termini C, Gillette JM. Maintenance of murine hematopoietic stem cells requires CD82 expression. In preparation 2. Marjon KD*, Karlen KL*, Saito-Reis C, Termini C, Gillette JM. CD82 deficiency in female mice results in glucose resistance and obesity. In preparation. * Co-first authors. 3. Rojas-Hernandez CM, Nemunaitis J, Marjon KD, Bustamante D, Zhang Q, Gillette JM. Chronic Lymphocytic Leukemia with Neurological Involvement: A Rare Phenomenon and the Need for Better Prognostic Markers.