ROUND TABLE 1: Health risk management Health examinations in different workplaces

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ROUND TABLE 1: Health risk management Health examinations in different workplaces Dr María del Rosario Pérez Department of Public Health, Environmental and Social Determinants of Health International Conference on Occupational Radiation Protection, Vienna, Austria, 1-5 December 2014

Health is a human right 2

WHO's definition of "health" Health is a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity. (WHO Constitution,1948) 3

The global workforce The global workforce represent half of the world s population. Workers are the major contributors to economic and social development. Workers' health is determined not only by workplace hazards but also by social and individual factors including access to health services 4

Health promotion Health promotion is the process of enabling people to increase control over, and to improve, their health. It includes improvement of individual behavior, as well as a wide range of environmental and social interventions to promote and sustain health (education, housing, energy, food, employment, air quality, water quality, sanitation, chemical safety, radiation safety, ) 5

Health Care Quality Dimensions Safety Effectiveness Patient-centeredness Timeliness Efficiency Equality 6

Health expenditure: large inequalities (between and within countries) Availability Accessibility Affordability (map: health expenditure) 7

Universal Health Coverage (UHC) UHC means that all people have access to health services without suffering financial hardship paying for them (sufficient quality and effectiveness...) Population coverage, service coverage and cost coverage Occupational health services within UHC 8

Environmental burden of disease (BoD) Nearly one quarter of the global disease burden is attributable to the modifiable environment: 24% of the number of years of healthy life lost due to disease; 23% of the mortality associated with the diseases. WHO report 2006 Although this is a significant contribution to the overall BoD, it is a conservative estimate because there is as yet no evidence for many diseases. 9

Occupational Health Hazards and Global Burden of Disease (GBoD) Approximately 2 million annual deaths worldwide are due to work-related diseases. This represents an average of 5,500 deaths per day. Workers suffer 270 million occupational accidents and 160 million occupational diseases each year. Overall BoD is measured by the Disability-Adjusted Life Year (DALY), expressed as number of years lost due to illness, disability or early death. Further research is still needed to precise the magnitude of this GBoD attributable to occupational radiation exposure. 10

WHO's global plan of action on 11 workers' health The 60 World Health Assembly endorsed the WHO global plan of action on workers' health 2008-2017 (resolution WHA60.26/ 2007) and urged WHO to: Promote the implementation of the global plan of action on workers' health at national and international level. Strengthen collaboration with ILO and other related international organizations and to stimulate joint regional and country efforts on workers' health. Maintain and strengthen the network of WHO collaborating centres for occupational health.

GOHNET The Global Occupational Health Network (GOHNET) includes ~70 WHO Collaborating Centres that support the implementation of the Global Plan of Action on Workers' Health. 12

WHO Global Plan of Action on Workers Health 2008-2017 This Global Plan of Action includes: Primary prevention of occupational hazards; Protection and promotion of health at work; Employment conditions; and Better response from health systems to workers health. 13

Global Plan of Action on Workers Health: common principles 1. All workers should be able to enjoy the highest attainable standard of physical and mental health and favorable working conditions. 2. The workplace should not be detrimental to health and wellbeing. 3. Primary prevention of occupational health hazards is a priority. 4. All components of health systems should be involved in an integrated response to the specific health needs of working populations. 5. The workplace can also serve as a setting for delivery of other essential public-health interventions, and for health promotion. 6. Activities should be planned, implemented and evaluated with a view to reducing inequalities in workers health within and between countries. 7. Workers, employers and their representatives should participate. 14

WHO's global plan of action on workers' health: objectives 1. to devise and implement policy instruments on workers' health; 2. to protect and promote health at the workplace; 3. to improve the performance of and access to occupational health services; 4. to provide and communicate evidence for actions and practice; 5. to incorporate workers' health into other policies. 15

Objective 1: to devise and implement policy 16 instruments on workers health National health policies and national action plans on workers' health National approaches to prevention of occupational diseases and injuries Measures to minimize the gaps in terms of levels of risks and health status between different groups of workers (e.g. young workers, gender issues, migrant workers, ) Support to Ministries of Health to provide leadership for activities related to workers' health

17 Objective 2: to protect and promote health at the workplace Assessment and management of health risks at the workplace. Endorsement, adoption and enforcement basic occupational health standards, building collaboration between the competent regulatory agencies. Capacity building for primary prevention of occupational health hazards (healthy practices, health promotion culture). Prevention of non-communicable diseases (e.g. cancer, cardiovascular are relevant for radiation exposure). Provision of guidance and tools

Objective 3: to improve the performance of and access to occupational health services Coverage and quality of occupational health services. Building institutional capacities for planning, delivering and monitoring OH services, dissemination of information and provision de specialized expertise. Development of human resources for workers' health (postgraduate and basic training, target primary health care physicians). Provision of tools, information products, training packages, good OH practices. 18

Objective 4: to provide and communicate evidence for action and practice Design systems for surveillance of workers' health to identify and control occupational hazards. Establish national information systems and building capability to estimate occupational burden of disease Create registries of occupational exposure, occupational accidents and occupational diseases. Improving early detection, reporting and learning. Framing a research agenda and fostering research. Increase awareness and knowledge about work & health links 19

Objective 5: to incorporate workers health 20 into other policies Promoting inclusion of workers' health in other sectors' policies. Workers' health considered in the context of trade policies. Assessment of the impact of employment policies. Considering environmental protection aspects and plans for emergency preparedness and response. Workers' health incorporated in primary, secondary and higher level education and vocational training.

Implementation of the Global Plan of Action on Workers' Health WHO to engage in partnerships and joint action with ILO and other organizations of the UN systems, employers' organizations, trade unions and other stakeholders from the civil society (NGOs) and private sector. From the radiation protection perspective this Plan of Action provides a robust framework to integrate occupational radiation protection into the broader concept of workers' health. Health surveillance in different workplaces is part of it. 21

Workers health surveillance vs, occupational health surveillance Workers health surveillance : assessment of workers health by means of detection and identification of diseases/ abnormalities. It may include clinical examination, biological monitoring, surveys, imaging procedures, reviews of workers radiation dose records and workers' health records. Occupational health surveillance : collection of information about conditions in the workers' health as well as in the working environment (hazards, risks). 22

Integrating radiation protection in the global occupational health agenda 2012 2015 23

Occupational radiation protection Purpose To provide an appropriate level of protection to workers by preventing tissue reaction (deterministic effects) and reducing the probability of stochastic effects to an acceptable level (ALARA) external exposure internal exposure radiation dose radiation risk radiation source exposure pathways exposed individual

Tissue reactions ICRP Statement on Tissue Reactions / Early and Late Effects of Radiation in Normal Tissues and Organs Threshold Doses for Tissue Reactions in a Radiation Protection Context (ICRP Publication 118, Ann. ICRP 41:1/2, 2012). Particular relevant for ORP concerning risk of circulatory disease and cataracts: New evidence of higher incidences of injury than expected after lower doses; hence, threshold doses appear to be lower than previously considered. A threshold dose of 500 mgy is proposed for practical purposes, irrespective of the dose rate.

Radiation-induced cataract & occupational health Early diagnosis possible (opacity at the posterior subcapsular region) but there is no established medical treatment to mitigate the radiation injury. Lens replacement is a well-established and effective surgical procedure for treating cataract. However, it requires access to specialized surgical services and has associated costs with implications on the healthcare system. Radiation-induced cataract is preventable.

Cataract: workers at risk Relatively uniform whole-body radiation exposures; Highly non-uniform radiation exposures in which the head may be particularly exposed; Weakly penetrating radiation exposures (beta particles, photons of low energies)

Cancer risk at low-dose: the LNT approach For the purposes of radiation protection it is assumed that the risk at low doses is proportional to the dose (i.e. radiation exposure always poses some risk, albeit very small at low doses) Categories at risks: all occupationally exposed workers 28

Common scenarios of workers' exposure to IR Medical applications of radiation (about 75% of exposed workers) Mines, mineral processing plants, oil, gas and other extractive industries (NORM ) Radiation sources used for industrial purposes (e.g. construction, manufacturing and food industries) Nuclear industry (NPPs, nuclear fuel cycle) Radiation or radioactive materials used for academic, research and/or development purposes Radiation emergencies 29

ORP of health workers 1895 Early 20 th century The golden rules: Time Distance Shielding The 3 principles of RP: Justification of practices Optimization of protection Limitation of dose 30

ORP of health workers 1895 Early 20 th century TODAY Same RP principles and "golden rules". The conditions for their implementation have changed. ORP in medical settings has to address the new challenges of modern technology and adapt to evolving conditions 31 Today

Health workers occupationally exposed to radiation Annually worldwide, about 7 million health workers incur radiation doses attributable to their occupation. Differences in the exposure conditions as well as in the level of radiation protection knowledge and skills are substantial. Physicians specialized in the use of IR: diagnostic radiologists, interventional radiologists, nuclear medicine physicians, radiation oncologists; Medical physicists, radiographers, radiation technologists, radiopharmacists, nurses; Physicians who use IR modalities in their practice (e.g. cardiologists, vascular surgeons, orthopedists, urologists, gastroenterologists). 32

33 Health workers' risks In general the doses and associated risks are higher in staff involved in interventional procedures. In particular regarding cataract, the lens doses and risks are higher for staff involved in: fluoroscopy guided interventional procedures; CT-guided interventional procedures; nuclear medicine procedures (e.g. preparation of radiopharmaceuticals, PET/CT, cyclotrons); manual brachytherapy.

Occupational exposure to radon Radon concentration may be very high in enclosed workplaces such as underground mines, caves, tunnels, thermal baths, spas, etc. Concentrations in the range between 5000 and 28000 Bq/m 3 have been reported in underground mines. Health surveillance programmes should consider co-morbidities (e.g. dust inhalation resulting in pneumoconiosis) 34

Radon exposure and workers' health risks Radon is a radioactive inert gas produced from the radioactive decay of uranium in rocks and soil, that escapes into the air and tends to concentrate in enclosed spaces (e.g. underground mines, houses, other buildings). It is the second cause of lung cancer after smoking (3-14% of cases would be attributable to radon). Most of the radon-induced lung cancer cases occur among smokers. The risk increases proportionally with the exposure (significant association observed at radon concentrations >100 Bq/m3) 35

Occupational exposure in NORM industries Natural Occurring Radioactive Materials (NORM) that are present in earth crust can be brought to the surface due to human activities (e.g. extractive industries). Exposure scenarios: mineral mining, processing and milling (e.g gold, copper, nickel, iron, coal, phosphate, others), mineral sands, oil and gas production, electricity generation with coal & peat, ceramics and building materials, ground water purification, sewage treat, phosphogypsum landfill,, others. NORM industries produce 80% of the worldwide annual collective dose from occupational exposures, excluding U mining (UNSCEAR 2000). Individual doses can be substantially high.. 36

NORM exposure and workers' health risks Most NORM contains radionuclides from the chains resulting from the decay of uranium-238 (238U), uranium-235 (235U) and thorium-232 (232Th). Workers may be exposed either: 37 internally through inhalation of radon gas or inhalation of radioactive aerosols in dusty working conditions, Internally through ingestion, and/or externally from gamma emitters.. Radon is an inert gas alpha emitter- risk: lung cancer. Radium (alpha, beta and gamma), affinity for chloride ions, "bone seeker"- risk:, bone cancer, lymphoma, leukemia and aplastic anemia, other cancers.

Nuclear emergency workers' health risks Occurrence of acute radiation effects will depend on the dose e.g.: while observed n Chernobyl liquidators, (ARS), no deterministic effects were observed in Fukushima emergency workers. Increased risk of cataract and circulatory disease may be considered if the doses exceed the threshold level (around 500 mgy ). Thyroid cancer risk is the most common stochastic risk after intake of radioactive iodine (higher for young workers, function of dose). Other radiation-related cancer risks will depend on the dose level, as well as on the exposure pathways, and radionuclides involved. Mental health disorders & psychosocial impact are health consequences most affecting radiation emergency workers. 38

Particular considerations applicable to all occupational exposure scenarios Particular considerations for female workers Pregnant female workers Female workers of reproductive capacity Female workers while they are breastfeeding in case there is a risk of internal exposure to radionuclide in the workplace (e.g. health workers in a nuclear medicine service) 39