For additional information visit: or contact Liliane Clermont-Wocker:

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International Symposium on Usher Syndrome Usher syndrome is the most common form of hereditary deaf-blindness. A broad alliance of institutions presents the 4th International Scientific Symposium on Usher Syndrome and the International Patient Symposium (10th Annual USH Connections Conference) at the Johannes Gutenberg University of Mainz, Germany. The International Symposium on Usher Syndrome will convene at the Atrium Hotel Conference Centre, Mainz on July 19-21, 2018, bringing together the world s leading experts from different fields of research (diagnostics, genetics, therapy, structural, molecular and cell biology) to present the latest developments in Usher syndrome. The 2-day Research Symposium on July 19-20, 2018 will enable the exchange of ideas and knowledge among scientists, clinicians and geneticists in order to facilitate novel research and insights in therapeutic strategies for Usher syndrome. The International Patient Symposium (USH Connections Conference) will convene on July 21, 2018, bringing together professionals with those affected by Usher syndrome around the world. About Usher Syndrome Usher syndrome is the leading cause of hereditary deaf-blindness in the world. Approximately 400,000 people worldwide are affected by this genetic disorder. Children with Usher syndrome are born with or develop hearing loss and the vestibular system can be affected too, which adversely affects their balance. Early in life, they will experience symptoms of a progressive vision disorder known as retinitis pigmentosa (RP). Initially, they will develop night blindness, followed by a narrowing of the visual field, commonly known as tunnel vision. Symptoms and disease progression vary from person to person. Most individuals with Usher syndrome are legally blind by the time they are young adults. There is currently no treatment for Usher syndrome. However, there are a number of treatments in or close to clinical trials, which will potentially help people with Usher syndrome. 2-day Research Symposium on Usher Syndrome July 19-20, 2018 Patient Symposium (USH Connections Conference) July 21, 2018 The Atrium Hotel Flugplatzstr. 44 D-55126 Mainz, Germany For additional information visit: www.ush2018.org or contact Liliane Clermont-Wocker: ush2018@uni-mainz.de SPONSORSHIP AND EXHIBITOR OPPORTUNITIES This event is anticipated to be the largest gathering of the Usher syndrome community in Europe, connecting the world s leading experts with individuals and families affected by Usher syndrome. 300 family members and professionals are expected to participate. The Symposium Committee invites you to take advantage of this wonderful opportunity to sponsor or exhibit at the International Symposium on Usher Syndrome.

International Symposium on Usher Syndrome Sponsorship Benefits Sponsor 2-day Scientific Symposium on Usher Syndrome (July 19-20, 2018) Gold Sponsor 2-day Scientific Symposium on Usher Syndrome 5.000 Complimentary exhibitor table (137 x 40 cm), an additional table can be booked for 500 Sponsor of Poster Award at scientific Symposium Up to three pieces pre-approved marketing materials distributed to attendees at the International Symposium on Usher Syndrome (at sponsor s expense) Free registration for up to two representatives to the International Scientific meeting Silver Sponsor 2-day Scientific Symposium on Usher Syndrome 2.500 Complimentary exhibitor table (137 x 40 cm) Up to two pieces pre-approved marketing materials distributed to attendees at 2-day Research Symposium on Usher Syndrome Sponsor of Poster Award at the 2-day Research Symposium on Usher Syndrome Free registration for up to one representative to the 2-day Research Symposium Bronze Sponsor for 2-day Scientific Symposium on Usher Syndrome 750

Sponsor Patient Symposium (July 21, 2018) Gold Sponsor Patient Symposium: 3.000 Company logo displayed on website in the abstract book Up to three pieces pre-approved marketing materials distributed to attendees at the Patient day (at sponsor s expense) Presenting company poster Complimentary exhibitor table (137 x 40 cm), an additional table can be booked for 500 Free registration for up to two representatives to the Patient Symposium Silver Sponsor 1-day Patient Symposium on Usher Syndrome 1.500 Complimentary exhibitor table (137 x 40 cm) Up to two pieces pre-approved marketing materials distributed to Patient Symposium (at sponsor s expense) Free registration for up to one representative to the Patient Symposium Bronze Sponsor for Patient Symposium on Usher Syndrome 750 [package 1] Free registration for up to one representative to Patient Symposium Bronze Sponsor for Patient Symposium on Usher Syndrome 750 [package 2] Exhibitor table (137 x 40 cm) Free registration for up to one representative to the Patient Symposium Bronze Sponsor for Patient Symposium on Usher Syndrome 750 [package 3] Up to one piece pre-approved marketing materials distributed to Patient Symposium (at sponsor s expense) 1 subject to approval

Cancellation Written cancellations received by March 15, 2018 will be honored with a full refund. No refunds will be issued after March 16, 2018. To register as a sponsor or exhibitor, please complete and return this form with payment by March 15, 2018 to: Liliane Clermont-Wocker Johannes Gutenberg University of Mainz Institute of Molecular Physiology Molecular Cell Biology Johann-Joachim-Becher-Weg 7 55099 Mainz, Germany Phone +49 6131 3923934 Fax +49 6131 3923815 or email to: ush2018@uni-mainz.de COMPANY INFORMATION Company Address City State Postal Code Country Phone (+) Website Company Description: Please enclose a description of the products or services provided by your organization in 50 words or less. This description will be included in the program and on the Symposium website. Submit your high resolution Company Logo to ush2018@uni-mainz.de (latest at March 15, 2018). CONTACT INFORMATION Phone Number Email Address FEES AND PAYMENT Sponsorship Levels 2-day scientific Symposium on Usher Syndrome Gold Sponsor - 5.000 Silver Sponsor - 2.500 Bronze Sponsor - 750 Patient Symposium Gold Sponsor - 3.000 Silver Sponsor - 1.500 Bronze Sponsor - 750 package No:

PAYMENT INFORMATION Bank Transfer Please transfer to BANK: Deutsche Bundesbank Filiale Mainz Account : Landeshochschulkasse Mainz IBAN: DE25 5500 0000 0055 0015 11 BIC: MARKDEF 1550 Reason for Payment: 6101 28286 9652402 Your Please note: As part of some sponsorship packages, you will receive a complimentary exhibit space including one or two representatives. If you would like to take advantage of this opportunity, please fill in the information below for your exhibit representatives. Exhibit Representative 1 Exhibit Representative 2 (Gold Sponsor only) For additional information, visit: www.ush2018.org or send an e-mail to ush2018@uni-mainz.de