Cosmetic/Medical Needling & Cosmetic Facial Acupuncture. Franck Joly L.Ac. MTOM Dipl.OM 4/19/2017

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Best perioperative pharmaceutical grade skin care ingredients for cosmetic & medical needling as well as cosmetic facial acupuncture treatments Presented by Franck Joly, Physician of Oriental Medicine & Medical Master Trainer for DermaConcepts Franck Joly L.Ac. MTOM Dipl.OM Discolsure: Physician of Oriental Medicine & Medical Master Trainer for DermaConcepts Exclusive US Distributor for Environ Skin Care Cosmetic/Medical Needling & Cosmetic Facial Acupuncture 1

Home Cosmetic Micro needling The Principle Micro channels are created through the surface of the skin via a process that we refer to as cosmetic needling, which dramatically increases the effectiveness of topically applied products This treatment is not painful and does not damage the skin the epidermis Epidermis: 0.1 0.2 mm thick Stratum Corneum: 0.01 0.02 mm thick SC: Stratum Corneum G: Stratum Granulosum S: Stratum Spinosum B: Basal Layer 2

The Principle Always roll vertically, obliquely and horizontally to ensure the best coverage of the selected area, using mild but firm pressure The Principle High concentration of micro channels through the correct rolling procedure epidermis Topical Roller 3

Medical Needling Recovery after needling / Epidermis remains intact between punctures Epidermis remains intact between punctures 4

Medical Needling pre & post Directly after needling Apply vitamins After cleaning Epidermal thickness in needled and unneedled skin in different sets (mm) Set No. of cases unneedled (group (B)) needled (group (A)) Mean SEM % change over time Mean SEM % change over time I (24 hrs) 12 (6, 6) ±13.1 1.7-13 1.9 - II (2 weeks) 12 (6, 6) ±13.2 1.8 0.8% 19.6 1.4 50.8% III (4 weeks) 12 (6, 6) ±14.8 1.4 13.0% 28.2 4.3 116.9% IV (8 weeks) 12 (6, 6) ±16 0.9 22.1% 31.2 1.2 140.0% p-value 0.00001; needled vs. unneedled 22% increase in thickness of epidermis over 8 weeks due to topical vitamins alone vs. 140% increase in thickness of epidermis over 8 weeks due to topical vitamins + PCI (needling) Associate Professor Dr. med. Matthias Aust, Germany 5

Cosmetic Facial Acupuncture 6

Vitamin A Dr. Des Fernandes Says: Ageing skin is a direct result of sun induced vitamin A deficiency. Correct the deficiency and you ll have more radiant skin. Dr. Des Fernandes Vitamin A vitamin A Retinoids (animal form) Carotenoids (plant form) acid alcohol ester (fat) Beta- Carotene Retinoic Acid Retinol Retinyl Palmitate Retinyl Acetate Retinyl Proprionate 7

Ester converted to acid in cell nucleus ACID (RETINOIC ACID) Needed in cell nucleus Harsh topically Causes sun sensitivity ALCOHOL (RETINOL) Irritating topically Causes sun sensitivity ESTER /FAT (RETINYL PALMITATE, ACETATE & PROPRIONATE) Storage form of Vitamin A NO sun sensitivity Converts to alcohol and acid accelerates healing acne treatment normalizes pigmentation healthy dermis and epidermis healthy collagen and elastin formation normalizes skin abnormalities Benefits of using vitamin A normalize cell differentiation 8

Before After (3-6 months) 5 months of daily use of Retinyl Palmitate 40% thickening of stratum spinosum 4 months of daily use of Retinyl Acetate 50% thickening of stratum spinosum Misconceptions Vitamin A thins the skin o vitamin A is essential in maintaining normal skin health, long term vitamin A use leads to histologically proven thicker skin Vitamin A makes the skin photo sensitive o motivation to mainly use the ester forms of vitamin A which has a photo protective action 9

Daily Use of Ester Forms of Vitamin A 2001 2005 2006 Daily Use of Ester Forms of Vitamin A Daily use of Ester forms of Vitamin A and Iontophoresis (every 2 weeks) for 6 months 10

Vitamin C Ester converted to acid ACID (ASCORBIC ACID) Easily degraded by light and air Irritating topically Causes sun sensitivity Ascorbyl Tetra isopalmitate ESTER (VC IP) Surrounded by fat molecules Increases penetration Highly stable NO sun sensitivity Converts to alcohol and acid Scientific Research has shown Vitamin C stimulates healthy collagen production treats pigmentation and sun damage antioxidant, recycles vitamin E offers natural UV protection 11

Vitamin E TOCOPHEROL AND TOCOPHERYL ACETATE Scientific research has shown This is a lipid soluble antioxidant which assists in protecting cell membranes Tocopherol protects the lipid phase in the products Benefits of Using These Friendly Forms of Vitamin A & C Better daily compliance from patients o Insures that patients use these non irritating forms of vitamins every morning and night, all year around especially during summer time without worrying about sun sensitivity Perfect tool for peri operative skin care treatments o Insures that patients prep their skin by priming fibroblasts before and right after any invasive procedures without worrying about skin irritation o Ideal forms to use with the home cosmetic micro needling 12

Daily use of Ester Forms of Vitamin A & VCIP for 3 months Daily use of Ester forms of Vitamin A & VCIP for 3 months Daily use of Ester forms of Vitamin A & VCIP for 8 years 13

Daily use of Ester forms of Vitamin A & VCIP for 5 years Daily use of Ester forms of Vitamin A & VCIP for 3 months Daily use of Ester forms of Vitamin A & VCIP for 5 years 14

Daily use of Ester forms of Vitamin A & VCIP for 5 years Hyaluronic acid SODIUM HYALURONATE (HYALURONIC ACID) Scientific research has shown A natural humectant that intensely hydrates and adds volume Helps maintain the skin structure, elasticity and flexibility Holds up to 1000 times its own weight in water and is known to play a vital role in the anti aging process 15

Daily use of Ester forms of Vitamin A, VCIP & Hyaluronic acid for 5 months Peptides PALMITOYL TETRAPEPTIDE 7 + PALMITOYL OLIGOPEPTIDE (MATRIXYL 3000) Scientific research has shown Stimulates the formation of healthy collagen and elastin 16

PALMITOYL OLIGOPEPTIDE + CERAMIDE 2 (DERMAXYL ) Scientific research has shown Assists with rehydration of the skin Hydroxypropyl Cyclodextrin + Palmitoyl Tri peptide 38 (MATRIXYL SYNTHÉ 6 ) Scientific research has shown Helps to create the appearance of smoother and plumper skin Ensures optimal architecture of skin tissue Pseudoalteromonas Ferment Extract + Hydrolyzed Wheat Protein + Hydrolyzed Soy Protein + Tri peptide 10 Citrulline + Tri peptide 1 (TRYLAGEN ) Scientific research has shown Acts on all stages of the collagen life cycle Stimulating the synthesis of collagen (stimulation) Controlling dimensions of the fibers (organization) Inhibiting enzymatic degradation (protection) Assists in maintaining youthful collagen 17

Daily use of Ester forms of Vitamin A & VCIP together with Amino peptides for 6 months Undecylenoyl Phenylalanine (SepiWhite MSH ) Scientific research has shown assists in controlling the formation of pigmentation may inhibit melanosome transfer Melanogenesis Ascorbyl Tetraisopalmitate (VC-IP) Niacinamide (Vit. B3) Retinyl Palmitate (Vit. A) Undecylenoyl Phenylalanine (Sepi-White MSH ) 18

Pigmentation case study Pigmentation case study 19

Daily use of Ester forms of Vitamin A, VCIP and Lactic acid for 8 months Daily use of Ester forms Vitamin A & VCIP + Home Microneedling for 12 months Daily use of Ester forms of Vitamin A & VCIP + Home Microneeding for 12 months 20

Daily use of Ester forms of vitamin A & VCIP + Home Micro needling for 5 years + 1 Medical Needling procedure THANK YOU! 21