Breast Cancer 100: Overview of Breast Cancer in Native Americans

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Breast Cancer 100: Overview of Breast Cancer in Native Americans Native American Cancer Research A Native operated non-profit corporation 3022 South Nova Road Pine, CO 80470-7830 Phone: 303-838-9359 Fax: 303-838-7629 www.natamcancer.org

Circle Topic Breast Cancer 100: Overview of Breast Cancer in Native Americans Table of Contents Breast Cancer 100:... 3 Overview of Breast Cancer in Native Americans... 3 Introduction... 3 Why is breast cancer early diagnosis so important?... 4 What are examples of different types of breast cancer?... 5 What are hereditary forms of breast cancer?... 6 What is Triple Negative Breast Cancer?... 7 Page 1 of 7

Page 2 of 7

Native American Cancer Research 1-800-537-8295; http://www.natamcancer.org Breast Cancer 100: Overview of Breast Cancer in Native Americans Introduction Good health practices are important for Natives whether or not they have cancer A breast cancer patient still needs to take part in screening for cervix, colon, and/or prostate (for males) cancers Providers sometimes are so focused on the primary / first type of cancer that they may forget to remind the patient to continue screening for other types of cancer. Breast cancer is higher among Natives from the Northern Plains in comparison to those from the Southwest But even among Natives living in the Southwest, breast cancer is increasing. Gay, Lesbian, Two-spirited women also develop breast cancer. Native men can also have breast cancer Scientists do not know how to prevent breast cancer yet This is why early diagnosis is so important Page 3 of 7

Why is breast cancer early diagnosis so important? Greater likelihood of survival Such as, 90% of white breast cancer patients diagnosed in early stage are alive and healthy 5 years later National data for American Indian breast patients has less than half are alive 5 years after breast cancer diagnosis But, this is not true for American Indians and Alaska Natives in NACR s Survivors Network 85% of these Native women are alive and well five years after breast cancer diagnosis. Not certain why the Network works. It may be due to the patients: Helping one another Finding ways to get into better care in a timely fashion Having hope because of the other people in the support program Combining Traditional Indian medicine with Western medicine Although all medical cancer treatments are hard, the earlier the diagnosis, the less invasive and intensive is the treatment Page 4 of 7

What are examples of different types of breast cancer? There are at least fifteen different types of breast cancer % Examples of types of pre-cancer or breast cancer Non-invasive (not cancer yet) 6.0 Ductal carcinoma, in situ 0.2 Lobular carcinoma, in situ 68.0 Ductal carcinoma 10.0 Lobular 3.0 Tubular 3.0 Cribriform 3.0 Medullary 2.0 Mucinous 2.0 Microinvasive 1.0 Papillary Invasive (cancer) 1.8 Other rare types (apocrine, metaplastic, adenodcystic cancers) The most common is in the milk ducts About half of all breast cancer is found in the upper outer area near the under arm Page 5 of 7

What are hereditary forms of breast cancer? No known cases of hereditary breast cancer among full bloods Risks of have hereditary breast cancer increases if you have a first degree relative or close blood family member who has / had breast cancer First degree relatives means your Parents (i.e., you came from their egg and sperm) Brother(s) or Sister(s) who came from the same womb as you Children who came from your womb Does not include family members we adopt in the Indian way If a first degree relative is diagnosed with breast cancer you have more risk than if it is an auntie or a cousin diagnosed with breast cancer If a first degree relative is diagnosed with a type of cancer other than breast you may be at greater risk (hereditary form) if they have: Colorectal Ovarian Prostate Because these each may have the same hereditary damages in BRCA1 or BRCA2 If first degree relative has different types of cancer, such as If one first degree relative has skin cancer and another has lymphoma, and another has kidney, The genetic mutation is NOT likely to be related to BRCA1 or BRCA2 Page 6 of 7

What is Triple Negative Breast Cancer? Breast tumor is negative for: Estrogen Progesterone HER2/neu genetic marker 1st noticed among African-American women diagnosed at young age Aggressive cancers No information about how common this is among AIANs But there are Natives who also have African-American blood / ancestry Page 7 of 7