Sierra Sacramento Valley EMS Agency

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Sierra Sacramento Valley EMS Agency BLS AUTO-INJECTOR EPINEPHRINE ADMINISTRATION OPTIONAL SKILL (UPDATED 08/2017)

In order for PSFA, EMR or EMT personnel to administer auto-injector epinephrine, they must: Be part of the organized EMS system, functioning under the oversight of an S-SV EMS approved BLS optional skills provider Be authorized by the approved BLS optional skills provider to administer auto-injector epinephrine Have received adequate training on auto-injector epinephrine administration Auto-injector epinephrine administration for severe asthma is only approved for EMT personnel

Education/Training Purpose and Objectives Purpose o To enable authorized PSFA, EMR and EMT personnel to administer epinephrine via auto-injector to patients in the prehospital setting Objectives o Identify causes, signs & symptoms of allergic reaction, anaphylaxis and severe asthma o Describe EMS care of a patient with allergic reaction, anaphylaxis, or severe asthma, including indications for the administration of epinephrine

Education/Training Purpose and Objectives Objectives (cont.) o Demonstrate knowledge of dosages, administration methods, actions, indications and contraindications of epinephrine administration to a patient with anaphylaxis or severe asthma o Demonstrate knowledge of storage, inspection, handling and disposal of auto-injector epinephrine devices o Demonstrate ability to properly administer epinephrine via auto-injector device

Allergic Reaction/Anaphylaxis Causes, Signs & Symptoms

Allergic Reaction/Anaphylaxis Immune System Overview o The immune system is part of the circulatory system o It helps protect the body from foreign substances that might be damaging (viruses, bacteria, toxins, etc.) o Substances that the body recognizes as foreign are called antigens

Allergic Reaction/Anaphylaxis Antigens and Antibodies o Antigens enter the body through contact with the skin (absorption), a bite or sting (injection), gastrointestinal tract (ingestion), or respiratory system (inhalation) o When an antigen enters the body, the immune system produces an antibody to that substance o Antibodies protect the person if they are exposed to the same substance again o The next time an antigen is found in the body, antibodies will quickly identify it and attack

Allergic Reaction/Anaphylaxis Allergic Reaction o An exaggerated response of the body to a foreign substance (allergen) by neutralizing or getting rid of the substance o One of the most common health problems in the United States o Allergic reactions range from mild (slow onset with minor symptoms) to severe/life threatening (sudden onset with major symptoms affecting the airway, breathing and circulation)

Allergic Reaction/Anaphylaxis Allergic Reaction Signs & Symptoms (slow onset) o Hives o Pruritus o Flushing o Rash o Nasal congestion o Watery eyes o Angioedema (swelling) not involving the airway

Allergic Reaction/Anaphylaxis Anaphylaxis o Sudden and rapid onset of severe symptoms o A reaction of an antigen and an antibody resulting in the release of histamine, causing the blood vessels to dilate and capillaries to leak fluids into surrounding cells o Profound dilation of blood vessels causes the blood pressure to fall resulting in shock o Fluid leaking from the capillaries results in profuse swelling of the skin, mucosa, face, tongue and airway

Allergic Reaction/Anaphylaxis Anaphylaxis Signs & Symptoms (rapid onset) o Respiratory distress o Bronchospasm/wheezes/ diminished breath sounds o Hoarseness &/or stridor o Edema involving the airway o Hives &/or swelling (face, tongue, lips, extremities) o Hypotension (SBP < 90)

Allergic Reaction/Anaphylaxis Common Causes of Allergic Reactions/Anaphylaxis

Asthma Causes, Signs & Symptoms

Asthma Asthma Triggers o Exposure to various allergens can trigger asthma signs/symptoms, these triggers are different from person to person and can include: Airborne substances (pollen, dust mites, mold spores, etc.) Respiratory infections, such as the common cold Physical activity (exerciseinduced asthma) Air pollutants and irritants, such as smoke Cold air Certain medications, including beta blockers, aspirin, ibuprofen, naproxen Strong emotions and stress Sulfites and preservatives added to some types of foods and beverages Gastroesophageal reflux disease (GERD)

Asthma Asthma Pathophysiology o Increased tracheal and bronchial reactivity Causes widespread reversible airway narrowing (bronchospasm) with increased mucus production

Asthma Asthma Signs & Symptoms o Wheezing o Coughing o Shortness of breath o Chest tightness/pain o Patient looks tired o Cyanosis

Assessment & Treatment Of: Allergic Reaction Anaphylaxis Severe Asthma

Assessment & Treatment Assessment o Assess respiratory status, manage airway and assist ventilations as appropriate During anaphylaxis the tongue may become so swollen that it blocks the airway positioning can help make breathing easier During anaphylaxis airway adjuncts may be of limited value because the airway may be obstructed at the larynx you may need to use a BVM to force air past the swollen tissues BVM ventilations may be difficult due to narrowing of the airways from bronchoconstriction

Assessment & Treatment Assessment o Assess history/physical, determine degree of illness o Assess vital signs (including pulse oximetry if available) o Do not delay care of critical patients to ask detailed questions

Assessment & Treatment Treatment o Administer supplemental O 2 at appropriate rate If patient has signs of respiratory distress or is in anaphylactic shock, administer high flow O 2 via NRM or BVM o Place the patient in a position of comfort If hypotensive due to anaphylaxis, use the Trendelenburg position (supine with the feet about a foot above the head) If in respiratory distress, a sitting position may be preferred o Determine if epinephrine administration is appropriate

Assessment & Treatment Epinephrine Indications o Anaphylaxis (PSFA, EMR, or EMT) Patients with suspected anaphylaxis in severe distress o Severe Asthma (EMTs only) Patients with suspected asthma in severe distress

Assessment & Treatment Epinephrine o Generic name Epinephrine o Trade names EpiPen EpiPen Jr. Adrenaclick

Assessment & Treatment Epinephrine o Actions Dilates bronchioles (airways) Constricts blood vessels Increases heart rate and cardiac output o Onset and duration The patient notices improvement in seconds to minutes Epinephrine is short lived, lasting about 10 20 minutes

Assessment & Treatment Epinephrine o Contraindications/precautions Pulmonary edema Hypothermia Use with caution in patients > 35 years old, or with a history of coronary artery disease (CAD) or hypertension (HTN) There are no contraindications when used in a life-threatening situation

Assessment & Treatment Epinephrine o Drug interactions Potentiates other sympathomimetics Patients taking monoamine oxidase (MAO) inhibitors, antihistamines and tricyclic antidepressants may experience heightened effects

Assessment & Treatment Epinephrine o Side effects Ventricular arrhythmias Increased heart rate Chest pain/angina Hypertension Pallor Nausea Anxiety/excitement Dizziness Headache Vomiting

Assessment & Treatment Epinephrine o Dosage Adult (> 30 kg) One (1) adult auto-injector (0.3 mg) Pediatric (15 30 kg) One (1) pediatric auto-injector (0.15 mg)

Assessment & Treatment Epinephrine o Administration route Deep intramuscular (IM) injection Lateral thigh, midway between waist and knee

Assessment & Treatment Epinephrine Auto-Injector o Directions for use Grasp the auto-injector with the hand (forming a fist around the unit) with the black tip facing downward Immediately before use, remove the grey activation cap with the other hand, being careful not to touch the tip where the needle is located

Assessment & Treatment Epinephrine Auto-Injector o Directions for use (cont.) Place the black tip near the fleshy outer portion of the thigh The preferred method is to expose and cleanse the area to be used for medication administration, but the autoinjector is designed to work effectively through clothing if needed

Assessment & Treatment Epinephrine Auto-Injector o Directions for use (cont.) With a quick motion, swing out and jab firmly into the outer thigh, so that the injector is at a 90 0 angle to the thigh Hold firmly in the thigh for several seconds while the spring activated mechanism is released, and the dose of epinephrine is administered

Assessment & Treatment Epinephrine Auto-Injector o Directions for use (cont.) Remove the auto-injector and massage the injection site for approximately 10 seconds Check the tip of the auto-injector if the needle is exposed, the epinephrine dose was injected, if not, the previous steps should be repeated

Assessment & Treatment Epinephrine Auto-Injector o Directions for use (cont.) Most of the liquid stays in the auto-injector after the dose is administered and cannot be reused To avoid accidental needle stick, carefully return the autoinjector to its carrying tube (needle first) without replacing the grey safety cap (DO NOT RECAP THE NEEDLE) Properly dispose of the used auto-injector in an approved sharps container as soon as possible (ALS ambulance or receiving hospital)

Assessment & Treatment Reassessment o Reassessment after epinephrine administration Continually reassess the patient s airway, breathing and circulatory status until patient care is transferred to ALS personnel or the receiving hospital (as applicable) Recheck vital signs every five (5) minutes Monitor for signs of deterioration including: Decreasing mental status Increased breathing difficulty Decreasing blood pressure

Assessment & Treatment Reassessment o Reassessment after epinephrine administration (cont.) If patient worsens, contact medical control (if able) and request permission to administer an additional dose of epinephrine (if available) Initiate CPR and AED if the patient becomes pulseless If patient condition improves, provide supportive care High flow O 2 Treat for shock (hypoperfusion)

Epinephrine Auto-Injector Storage/Use Epinephrine Auto-Injector Administration Reporting and Documentation

Epinephrine Auto-Injector Storage/Use Storage/Use Requirements: o Store in original container, easily accessible for emergency use o Store at room temperature, out of direct sunlight o Regularly inspect for color and clarity Replace/do not use if the liquid is discolored or cloudy o Regularly check expiration date Do not use past labeled expiration date

Epinephrine Auto-Injector Administration Reporting and Documentation Administration Reporting and Documentation o Inform other appropriate EMS providers and/or the receiving hospital of any pertinent details related to the epinephrine administration o Adequately document the epinephrine administration for reporting and QI review requirements