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An immunization that does not fall under one of the exclusions in the Certificate of Coverage is considered covered after the following conditions are satisfied: (1) FDA approval; (2) explicit ACIP recommendation published in the Morbidity & Mortality Weekly Report (MMWR) of the Centers for Disease Control and Prevention (CDC). Implementation will typically occur within 60 days after publication in the MMWR. In the case of a public health emergency (as defined by the Centers for Disease Control or state or local public health departments) UnitedHealthcare may choose to apply preventive benefits to a new vaccine if the vaccine has FDA approval, even if an ACIP recommendation has not been announced. NOTE: Trade Name(s) column: brand names/trade names are included, when available, as examples for convenience only. Coverage pursuant to this Coverage Determination Guideline is based solely on the procedure codes. Age Group column: This column is provided for informational only. For purposes of this document: means age 18 years and up; means age 0-18 years. Benefit Limits column: Benefit Limits in bold text are from FDA labeling and ACIP recommendations. Codes that indicate For applicable description are limited to the age(s) listed in the code PREVENTIVE IMMUNIZATIONS Immunization Administration Preventive when included as part of a preventive immunization. 90460 Immunization administration through 18 years of age via any route of administration, with counseling by physician or other qualified health care professional; first or only component of each vaccine or toxoid administered 90461 Immunization administration through 18 years of age via any route of administration, with counseling by physician or other qualified health care professional; each additional vaccine or toxoid component administered (List separately in addition to code for primary procedure) 90471 Immunization administration (includes percutaneous, intradermal, subcutaneous, or intramuscular injections); one vaccine (single or combination vaccine/toxoid) 90472 Immunization administration (includes percutaneous, intradermal, subcutaneous, or intramuscular injections); each additional vaccine (single or combination vaccine/toxoid) (List separately in addition to code for primary procedure) 90473 Immunization administration by intranasal or oral route; one vaccine (single or combination vaccine/toxoid) 90474 Immunization administration by intranasal or oral route; each additional vaccine (single or combination vaccine/toxoid) (List separately in addition to code for primary procedure) (0-18yr), n/a n/a n/a - n/a - n/a - n/a - G0008 Administration of influenza virus vaccine n/a - G0009 Administration of pneumococcal vaccine n/a - G0010 Administration of hepatitis B vaccine n/a - 0771 Vaccine administration n/a - 1

(revenue code) Meningococcal 90620 Meningococcal recombinant protein and outer membrane vesicle vaccine, Serogroup B, 2 dose schedule, for 90621 Meningococcal recombinant lipoprotein vaccine, serogroup B, 3 dose schedule, for 90644 Meningococcal conjugate vaccine, serogroups C & Y and Haemophilus influenzae b vaccine (Hib-MenCY), 4 dose schedule, when administered to children 2-15 months of age, for 90733 Meningococcal polysaccharide vaccine, serogroups A, C, Y, W-135, quadrivalent (MPSV4) for subcutaneous 90734 Meningococcal conjugate vaccine, serogroups A, C, Y and W-135, quadrivalent (MenACWY), for Hepatitis A 90632 Hepatitis A vaccine (HepA), adult dosage, for Haemophilus influenza b (Hib): Human Papilloma Virus (HPV) Seasonal Influenza ( flu ) 90633 Hepatitis A vaccine (HepA), pediatric/ adolescent dosage-2 dose schedule, for 90634 Hepatitis A vaccine (HepA), pediatric/adolescent dosage-3 dose schedule, for 90636 Hepatitis A and hepatitis B vaccine (HepA- HepB), adult dosage, for 90647 Haemophilus influenzae b vaccine (Hib), PRP- OMP conjugate, 3 dose schedule, for 90648 Haemophilus influenzae b vaccine (Hib), PRP-T conjugate, 4 dose schedule, for intramuscular 90649 Human Papilloma virus vaccine, types 6, 11, 16, 18, quadrivalent (HPV4), 3 dose schedule, for 90650 Human Papilloma virus vaccine, types 16, 18, bivalent (HPV2), 3 dose schedule, for 90651 Human Papillomavirus vaccine types 6, 11, 16, 18, 31, 33, 45, 52, 58, nonavalent (9vHPV), 3 dose schedule, for (0-18yr), Bexsero Benefit Limit: Age 10 and up. Trumenba Benefit Limit: Age 10 and up. MenHibrix Menomune - Menactra Menveo Havrix VAQTA Havrix VAQTA - Havrix Twinrix PedvaxHIB - ActHIB Hiberix - Gardasil4 Benefit Limit: Ages 9-26yrs. Ends on 27 th Cervarix Benefit Limit: Ages 9-26yrs. Ends on 27 th Gardasil9 Benefit Limit: Ages 9-26yrs. Ends on 27 th - 90630 Influenza virus vaccine, quadrivalent (IIV4), split virus, preservative free, for intradermal Fluzone Intradermal Quadrivalent 90653 Influenza vaccine, inactivated (IIV), subunit, - - 2

Note: Additional new seasonal flu immunization codes that are recently FDAapproved, but are not listed here, may be eligible for preventive benefits as of the FDA approval date. adjuvanted, for 90654 Influenza virus vaccine, trivalent (IIV3), split virus, preservative-free, for intradermal 90655 Influenza virus vaccine, trivalent (IIV3), split virus, preservative free, when administered to children 6-35 months of age, for 90656 Influenza virus vaccine, trivalent (IIV3), split virus, preservative free, when administered to individuals 3 years and older, for 90657 Influenza virus vaccine, trivalent(iiv3), split virus, when administered to children 6-35 months of age, for 90658 Influenza virus vaccine, trivalent (IIV3), split virus, when administered to individuals 3 years of age and older, for 90660 Influenza virus vaccine, trivalent, live (LAIV3), for intranasal 90661 Influenza virus vaccine (cciiv3), derived from cell cultures, subunit, preservative and antibiotic free, for 90662 Influenza virus vaccine (IIV), split virus, preservative free, enhanced immunogenicity via increased antigen content, for Fluzone Intradermal Trivalent Fluzone No Preservative Afluria Fluzone No preservative Fluvirin Fluarix Flulaval (0-18yr), Benefit Limit: 18 years 64 years. Ends on 65 th Fluzone Afluria Flulaval Fluvirin Fluzone Flumist Benefit Limit: Ages 2 49 Years. Ends on 50 th birthday Flucelvax Benefit Limit: Ages 18 years and up High Dose Fluzone Benefit Limit: Ages 65 years and up 90664 Influenza virus vaccine, live (LAIV), pandemic formulation, for intranasal 90666 Influenza virus vaccine (IIV), pandemic formulation, split virus, preservative free, for 90667 Influenza virus vaccine (IIV), pandemic formulation, split virus, adjuvanted, for 90668 Influenza virus vaccine (IIV), pandemic formulation, split virus, for Flumist Benefit Limit: Ages 2 49 Years. Ends on 50 th - - - - - - 90672 Influenza virus vaccine, quadrivalent, live (LAIV4), for intranasal Flumist (LAIV4) Benefit Limit: Ages 2 49 Years. Ends on 50 th 3

(0-18yr), Pneumococcal polysaccharide (PPSV23) Pneumococcal conjugate 90673 Influenza virus vaccine, trivalent (RIV3), derived from recombinant DNA (RIV3), hemagglutinin (HA) protein only, preservative and antibiotic free, for 90685 Influenza virus vaccine, quadrivalent (IIV4), split virus, preservative free, when administered to children 6-35 months of age, for 90686 Influenza virus vaccine, quadrivalent (IIV4), split virus, preservative free, when older, for 90687 Influenza virus vaccine, quadrivalent (IIV4), split virus, when administered to children 6-35 months of age, for 90688 Influenza virus vaccine, quadrivalent (IIV4), split virus, when administered to individuals 3 years of age and older, for Q2034 Influenza virus vaccine, split virus, for (Agriflu) Q2035 Influenza virus vaccine, split virus, when older, for (AFLURIA) Q2036 Influenza virus vaccine, split virus, when older, for (FLULAVAL) Q2037 Influenza virus vaccine, split virus, when older, for (FLUVIRIN) Q2038 Influenza virus vaccine, split virus, when older, for (Fluzone) Q2039 Influenza virus vaccine, split virus, when older, for (not otherwise specified) 90732 Pneumococcal polysaccharide vaccine, 23- valent (PPSV23), adult or immunosuppressed patient dosage, when administered to individuals 2 years or older, for subcutaneous or 90670 Pneumococcal conjugate vaccine, 13 valent (PCV13), for Rotavirus 90680 Rotavirus vaccine, pentavalent (RV5), 3 dose schedule, live, for oral 90681 Rotavirus vaccine, human, attenuated (RV1), 2 dose schedule, live, for oral Diphtheria, tetanus toxoids, 90696 Diphtheria, tetanus toxoids, pertussis vaccine and inactivated poliovirus vaccine (DTaP-IPV), when administered to children 4 through 6 years of age, for Flublok Benefit Limit: Age 18 years and up. Fluzone Fluarix Flulaval Fluzone Quadrivalent Fluzone Quadrivalent Flulaval Fluzone Quadrivalent Agriflu Benefit Limit: Ages 18 years and up Afluria Flulaval Fluvirin Fluzone - Pneumovax 23 Prevnar 13 - (PCV13) ROTATEQ - Rotarix - Kinrix Quadracel 4

pertussis and polio inactive (DTap-IPV) Diphtheria, tetanus toxoids, pertussis, haemophilus influenza B, and polio inactive (DTap-IPV/Hib) Diphtheria, tetanus, pertussis (DTap) Diphtheria and tetanus (DT) Measles, Mumps, Rubella (MMR) 90698 Diphtheria, tetanus toxoids, pertussis vaccine, haemophilus influenzae Type b, and inactivated poliovirus vaccine (DTaP IPV/Hib), for 90700 Diphtheria, tetanus toxoids, and pertussis vaccine (DTaP), when administered to individuals younger than 7 years, for 90702 Diphtheria and tetanus toxoids adsorbed (DT) when administered to individuals younger than 7 years, for 90707 Measles, mumps and rubella virus vaccine (MMR), live, for subcutaneous 90710 Measles, mumps, rubella, and varicella vaccine (MMRV), live, for subcutaneous Polio (IPV) 90713 Poliovirus vaccine, inactivated (IPV), for subcutaneous or Tetanus and 90714 Tetanus and diphtheria toxoids adsorbed (Td), diphtheria (Td) preservative free, when administered to individuals 7 years or older, for intramuscular Tetanus, diphtheria toxoids and pertussis (Tdap) Varicella (VAR) ( chicken pox ) Diptheria, tetanus and pertussis, hep B, and polio inactive (DTaP- HepB-IPV) Zoster / Shingles (HZV) 90715 Tetanus, diphtheria toxoids and pertussis vaccine (Tdap), when administered to individuals 7 years or older, for 90716 Varicella virus vaccine (VAR), live, for subcutaneous 90723 Diphtheria, tetanus toxoids, pertussis vaccine, hepatitis B, and inactivated poliovirus vaccine (DTaP-HepB-IPV), for intramuscular 90736 Zoster (shingles) vaccine (HZV), live, for subcutaneous injection Hepatitis B 90740 Hepatitis B vaccine (HepB), dialysis or immunosuppressed patient dosage, 3 dose schedule, for 90743 Hepatitis B vaccine (HepB), adolescent, 2 dose schedule, for (0-18yr), Pentacel - Daptacel Infanrix - MMR II - ProQuad - Ipol - Tenivac Decavac Adacel Boostrix Varivax - PEDIARIX Benefit Limit: Ages 0-6yrs. Ends on 7 th Zostavax Benefit Limit: Age 60 years and up. Recombivax - Recombivax (adolescent only) 5

90744 Hepatitis B vaccine (HepB), pediatric/adolescent dosage, 3 dose schedule, for 90746 Hepatitis B vaccine (HepB), adult dosage, 3 dose schedule, for 90747 Hepatitis B vaccine (HepB), dialysis or immunosuppressed patient dosage, 4 dose schedule, for 90748 Hepatitis B and Haemophilus influenza b vaccine (Hib-HepB), for Recombivax Energix-B Recombivax Energix-B (0-18yr), Energix-B - Comvax - Back to Main Menu 6