West Virginia University School of Medicine, Morgantown, West Virginia

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MARY CARROLL SHEMO, M.D., D.F.A.P.A. CURRICULUM VITAE Psychiatric Alliance of the Blue Ridge Office: (434) 984-6777 First Floor, Old Ivy Commons, 2496 Old Ivy Road, Suite 400 Fax: (434) 296-1412 22903-4895 PERSONAL DATA: Born: February 3, 1950, College Park, Maryland Citizenship: USA Husband: John Palmer David Shemo, M.D., FAPA Children: Bryna Carroll Shemo - 12/9/81 Cordelia Palmer Shemo - 8/11/86 EDUCATION: Degree: B.S., 1972 Wheeling Jesuit College, Wheeling, West Virginia Major: Biology Minors: Philosophy Degree: M.D., 1976 West Virginia University School of Medicine, Morgantown, West Virginia LICENSE TO PRACTICE: Virginia #0101031408 BOARD CERTIFICATION: Diplomate National Board of Medical Examiners 1977 Diplomate American Board of Psychiatry and Neurology 1980 PROFESSIONAL CAREER: June 1976 - July 1979 Residency in Behavioral Medicine and Psychiatry West Virginia University Medical Center, Morgantown, West Virginia June 1978 July 1979 July 1979 January 1980 January 1980 August 1987 June 1981 August 1987 December 1979 - present August 1987 - present Chief Resident Behavioral Medicine and Psychiatry West Virginia University Medical Center, Morgantown, West Virginia Fellowship in Child and Adolescent Psychiatry Student Health Psychiatrist Mental Health Section Head *Clinical Assistant Professor Department of Behavioral Medicine & Psychiatry *Psychiatrist private practice of adult and adolescent psychiatry Psychiatric Alliance of the Blue Ridge March 2000 present *Principal Investigator Psychiatric Alliance of the Blue Ridge Clinical Research Center ACADEMIC, CONSULTANT and COMMITTEE APPOINTMENTS:

2 1973-1979 Admissions Committee, Voting Member West Virginia University School of Medicine 1979 Behavioral Medicine and Psychiatric Resident Consultant Pain Clinic, West Virginia University Medical Center 1980-1987 Student Health Patient Education Committee Student Health, 1982-1987 Supervision of Psychiatric Residents Student Health, 1983-1987 Student Health Research Committee Student Health, 1984-1987 Student Health Quality Assurance Committee Student Health, 1985-1986 Panel Member, Medical Center Hour 1989-2000 Chairman, Clinical Committee Charter Hospital of Charlottesville 1996-1999 Practice Guidelines Steering Committee American Psychiatric Association 1987-present 1992-present *Supervision of Psychiatric Residents in Outpatient Therapy *Practice Research Network American Psychiatric Association 2001 Panel Member, Sumatriptan Succinate (Imitrex) GlaxoWellcome 2001 Consultant, Topiramate (Topamax) OrthoMcNeil Pharmaceutical 2001 Advisory Committee Member, Citalopram (Celexa) Forest Laboratories 2002- present Speakers Bureau, Lexapro Forest Laboratories HONORS: Presidential Scholarship, 1968-1972 Member, Gamma Pi Epsilon Jesuit Women s Honor Society, 1971 Graduated Magna Cum Laude, 1972 Class Valedictorian, 1972 Robert Wood Johnson Scholarships, 1972-1976 Member, Alpha Omega Alpha National Medical Honor Society, 1975 Vice President, Alpha Omega Alpha National Medical Honor Society, 1976 Diplomate of National Board of Medical Examiners, 1977

3 PROFESSIONAL SOCIETIES: Albemarle County Medical Society, 1980-present American Psychiatric Association, 1981-present Psychiatric Society of Virginia, 1981-present American College Health Association, Mid-Atlantic Chapter, 1982-1987 American Society of Clinical Psychopharmacology, 1994-present TEACHING, LECTURES and PAPERS PRESENTED: 1974 Human Sexuality, Birth Control and Venereal Disease, Lecture Series for College Coeds West Virginia University TEACHING, LECTURES and PAPERS PRESENTED cont: 1977 The Medical Complications of Drug Abuse, Six Hour Series Annual School of Alcohol and Drug Abuse West Virginia University Medical Center Department Behavioral Medicine & Psychiatry and the West Virginia Department of Mental Health 1977 An Overview of Psychotropic Medicine, Lecture Series for Graduate Students in Guidance and Counseling, West Virginia University, Morgantown, West Virginia 1978 The Diagnosis of organic Brain Syndrome Lecture Series for Medical Students West Virginia University School of Medicine, Morgantown West Virginia 1979-1987 Psychopathology Course, Small Groups For Medical Students Medical Aspects of Drug and Alcohol Abuse; Mental Health Concerns Resident Assistant Orientation 1980-1987 Presentations to Student Health Nurses (various topics) Psychotropic Medications, Drug Abuse, Stress Management and Clinical Uses of Hypnosis. 1981 The Clinical Uses of Hypnosis, Clinical Case Conference for Medical Students on the Inpatient Psychiatric Rotation 1981 Research Contributions to College Psychiatry American Psychiatric Association Annual Meeting 1982 The Treatment of Bulimia, Continuing Nursing Education University of Virginia, 1984 Student Mental Health and Eating Disorders Inter Sorority Council 1984 Eating Disorders, Presentation to Resident Assistants

4 Sweet Briar College, 1985 Articles on Eating Disorders for the Cavalier Daily and Iris student papers University of Virginia, 1985 The crisis of Young Adult Suicide, Medical Center Hour 1986 Lecture to Psychiatric Residents on Bulimia 1986 Eating Disorders, Family Practice Refresher Course 1986 Eating Disorders, Medical Center Hour 1986 Lecture to Student Health Faculty on Eating Disorders 1999 Seasonal Affective Disorder Albemarle County Medical Society Lecture RESEARCH EXPERIENCE: 1983 The Evaluation and Treatment of Stress in a University Population Using a Didactic Model 1987 A Comparative Study of Imipramine Versus Clomipramine in College Women With Eating Disorders 2001 Principal Investigator Training Society of Clinical Research Associates, Washington, D.C. 2001-2003 XXX Versus Placebo as Add-On Treatment in Subjects with Bipolar Disorder in the Outpatient Setting, phase IIIB, sponsored by Ortho-McNeil Pharmaceutical. 2002 A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Safety and Efficacy Study of XXX in Adults with Attention Deficit Hyperactivity Disorder (ADHD), phase II, sponsored by Shire Pharmaceutical. 2002 A Prospective, Multicenter, Open-Label Study of XXX in the Management of patients with Schizophrenia and Schizoaffective Disorder in General Psychiatric Practices, phase III, sponsored by Bristol Meyers Squibb. 2002 Beneficial Effects of Quitiapine Treatment in patients With Fibromyalgia, Case study, sponsored by AstraZeneca. Poster presented at the New Clinical Drug Evaluation Unit meeting (NCDEU) in Boca Raton, FLA, June 11, 2002. 2002 Examining Clinical Experience with XXX in Depression Trial, phase IV, sponsored by Forest Pharmaceuticals, Inc RESEARCH EXPERIENCE CONT:

5 2002-2003 A Double-Blind, Placebo-Controlled, Multicenter Study of the Long-Term Efficacy of XXX in the Maintenance of Antidepressant Effect in Geriatric Outpatients with Major Depressive Disorder; Protocol 068-01, phase III, sponsored by Merck Research Laboratories. 2002-2003 A Double-Blind, Multicenter, placebo- and Active-Controlled Acute and Extension Study of 2 Doses of XXX in the treatment of Patients with major Depressive Disorder. PN062-061, phase III, sponsored by Merck Research Laboratories. 2003 A Phase II, Randomized, Double-Blind, Parallel-Group, Placebo Controlled Safety and Efficacy Study of XXX in Children and Adolescents Aged 6-17 with oppositional Defiant Disorder (ODD), sponsored by Shire Pharmaceutical Development, Inc. 2003 present A Phase II, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Safety and Efficacy Study of XXX in Adults Aged 18-55 with Attention Deficit Hyperactivity Disorder (ADHD). 2003-present A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Flexible-Dose Study to Assess the Safety and Efficacy of XXX in the Treatment of Moderate to Severe Binge eating Disorder Associated with Obesity. Phase IIB, sponsored by Ortho-McNeil Pharmaceutical. 2003 present A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess the Efficacy and Safety XXX Versus Placebo for the Treatment of Social Anxiety Disorder (Generalized Type). Phase II, sponsored by UCB Pharma. 2003 present An Open Label Study of the Tolerability, Clinical Response, and Satisfaction in Adult Bipolar 1 Subjects Optimizing Initiation of Therapy Using Administration of Dermatological Precautions and XXX Titration Packs. Phase IV, sponsored by GlaxoSmithKline. 2004 Protocol for the Psychometric Validation of a Functional Status Questionaire Designed for Use in Bipolar Disorder. Sponsored by AstraZeneca. 2004 present Efficacy and Safety of XXX in Patients with Borderline Personality Disorder: A Randomized Flexible Dose Double-Blind Comparison with Placebo. Sponsored by Eli Lilly. 2004 present A Multicenter, Parallel-Group, Double-Blind, Phase III Comparison of the Efficacy and Safety of XXX to Placebo When Used as Adjunct to Mood Stabilizers (Lithium or Divalproex) in the Maintenance Treatment of Bipolar I Disorder in Adult Patients. Sponsored by AstraZeneca.