Joint Injection Workshop ACP Scientific Meeting February 28, Andrea M. Barker, MPAS, PA C Michael J. Battistone, MD

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Joint Injection Workshop ACP Scientific Meeting February 28, 2015 Andrea M. Barker, MPAS, PA C Michael J. Battistone, MD

Workshop Schedule 1:00 1:15 A Practical Approach to the Shoulder Exam 1:15 1:40 Arthrocentesis and Steroid Injections of the Knee and Shoulder 1:40 1:45 Transition 1:45 2:05 Hands on Session I* Shoulder Exams Knee Injections 2:05 2:25 Hands on Session II* Shoulder Exams Knee Injections * Joint Injection simulators are available during this time

Examination Performed Technique Adequate FROM BEHIND 1 Observation Adequate exposure General Scapular winging Observe as they disrobe for degree of discomfort Symmetry, scars, skin lesions, erythema, edema, atrophy Patient raises arms bilaterally Wall press 2 Palpation Bilateral Sternoclavicular joint Acromioclavicular joint Biceps tendon Lateral shoulder Inferior to acromion FACING PATIENT 3 Range of Motion 4 Motor Function of Rotator Cuff Bilateral ROM: Active forward elevation in scapular plane Painful arc (>90 ) Drop arm test Motor: Empty Can Test Supraspinatus Infraspinatus ROM: Active external rotation Motor: Active external rotation against resistance Scapular plane Neutral rotation (thumbs to ceiling) Scapular plane Full pronation (thumbs to floor) Resisted forward elevation Elbows at side Elbows at side Start with hands near midline Subscapularis Teres Minor Unilateral Motor: Belly Press Test Hand on abdomen Elbow anterior to midline Examiner pulls at forearm Watch for elbow to drop ROM: Active internal rotation along spine Observe patient from behind Motor: Lift Off Test ROM: Active external rotation with 90 shoulder abduction and 90 elbow flexion Hand at lumbar spine Actively lifts off back against resistance 90' shoulder abduction 90' elbow flexion Thumb points posterior Motor: Hornblower s Test External rotation as above against resistance Note: check passive range of motion if active is limited. This will identify mechanical block of motion versus shoulder weakness

Anatomy

5 Components of Shoulder Exam 1. Observation 2. Palpation 3. Range of Motion 4. Motor Function of the Rotator Cuff 5. Provocative Testing ADEQUATE EXPOSURE!!!

1. Observation Symmetry Skin lesions/scars Erythema Scapular winging Atrophy

2. Palpation Bilateral palpation from behind patient SC joint AC joint Biceps tendon (long head) Subacromial space (lateral and posterolateral) Note locations of tenderness to help guide examination

Start with active ROM and perform passive ROM if active is limited 4. Motor Function of Rotator Cuff Monitor each maneuver for pain as well as strength Pain but normal strength: tendonitis or partialthickness tear Pain with weakness: concern for full thickness tear Compare strength with unaffected side

Supraspinatus Abduction Forward elevation ROM: Active forward elevation in scapular plane Bilateral Elbows extended Thumbs to ceiling Painful Arc (pain >90 0 ABD) Drop Arm Test

Supraspinatus Abduction Forward elevation Motor: Empty Can Test Bilateral Internal rotation (thumbs toward floor) Elbows extended Downward pressure by examiner 90 or lower

Infraspinatus ROM: External rotation Bilateral Elbows at side, 90 degrees of flexion Examine for symmetry

Infraspinatus External rotation Motor: external rotation test Bilateral Elbows at side, 90 degrees of flexion Hands near midline Examiner resists ER

Subscapularis Internal rotation Motor: Belly Press Test Unilateral Elbow anterior to midline Examiner attempts pull arm off abdomen at the wrist

Subscapularis Internal rotation ROM: Internal rotation along spine Unilateral Repeat on unaffected side for comparison

Subscapularis Internal rotation Motor: Lift off Test Unilateral Dorsum of hand against lumbar spine Patient attempts to lift hand off back against resistance Resistance applied at wrist

Teres Minor External rotation ROM: External rotation in abduction Unilateral 90 degrees shoulder abduction 90 degrees elbow flexion Thumb toward ceiling Patient attempts ER hitchhiking

Teres Minor External rotation Motor: Hornblower s Test Unilateral 90 degrees shoulder abduction 90 degrees elbow flexion End position of ROM test Examiner resists ER

5 Provocative Testing Impingement Testing Hawkin s Test Neer s Test Biceps Testing Speed s Test AC Joint Testing Yergeson s Test Cross-arm Test Shoulder 90' abduction Scapular plane 90' elbow flexion Internal rotation + horizontal adduction Elbow extended Full pronation Maximal passive forward elevation of shoulder with scapular stabilization 60' forward elevation Hand in supination 20-30' elbow flexion Apply downward pressure to forearm Elbow at side, 90' flexion Palm in supination Resisted supination Active horizontal adduction

Subacromial Impingement Area between humeral head and acromion Narrowed space Bony changes Acromion type AC spurs Cuff arthropathy Soft tissue swelling Bursa Rotator cuff

Subacromial Impingement Testing Hawkin s Test Passive 90 abduction, 90 elbow flexion Scapular plane Maximal internal rotation Neer s Test Passive Elbow extended Pronation Sagittal plane Near to the ear

Biceps Tendinopathy Testing Speed s Test 60 forward elevation 20 30 elbow flexion Downward pressure at forearm Yergason s Test Elbow at side, 90 flexion Palm in supination Examiner attempts to pronate

Acromioclavicular Joint Testing Cross arm Test 90 forward elevation Maximal horizontal adduction Pain must be localized to AC joint for test to be positive

Neurologic Testing Spurling s Test Slight neck extension Rotation toward affected shoulder Axial load Neurologic Testing Motor Shoulder abduction, forearm supination (C5) Elbow flexion, wrist extension (C6) Elbow extension/wrist flexion/finger extension (C7) Finger flexion/thumb abduction (C8) Reflexes Biceps (C5, C6) Brachioradialis (C6) Triceps (C7, C8) Sensation Deltoid (C5) Radial aspect of arm/hand, thumb (C6) 3 rd digit (C7) Ulnar aspect of arm/hand and 5 th digit (C8)

Arthrocentesis and Corticosteroid Injections of the Knee and Shoulder

Am I Ready? Do I have a good indication? Do the risks outweigh the benefits? What size needle and syringe will I use? What medications do I want to use? Will I anesthetize the skin? Which approach is most reliable and least painful? What will be considered a successful outcome? What can I tell the patient to expect during & after?

Overview Contraindications/risks to corticosteroid (CS) injections Preparation prior to procedure Intra articular (IA) knee injection Indications Approach Patient positioning + procedure Subacromial (SA) injection of the shoulder Indications Approach Patient positioning + procedure

Contraindications/Cautions Prosthetic joint Recent surgical procedure involving the joint Joint surgery anticipated in the next 3 months Overlying cellulitis Supratherapeutic anticoagulation Medication allergies Suboptimal response to prior injection If concern for septic arthritis, contact orthopedics or rheumatology

Do Risks Outweigh Benefits? Significant Risks and Complications Infection 1 Post injection flare Bleeding Increase in blood glucose Lack of response/no improvement 2 Things to Consider Tendon rupture Skin atrophy/hypopigmentation Suppression of the hypothalamic pituitary axis

Pre Procedure Checklist 1. Informed consent 2. Documentation plan 3. Supplies prepared

Supplies KEY: Be consistent with needle gauge and syringe size This produces consistent resistance during injections; increased resistance suggests injection of medications into soft tissue/tendon

21 Gauge 1.5 Inch Needle + 10cc Syringe Recommended for SA and IA injections Fast delivery, can still feel resistance Can be used for aspiration 18 gauge needle + 20 30cc syringe Aspiration of large effusion or hemarthrosis

Medications Use single dose vials when possible 3,4

Anesthetics: Lidocaine + Bupivacaine Mix in syringe with CS Dilution and dispersion of steroid Decrease risk post injection flare, local atrophy Fast onset with lidocaine (1 2cc total) Facilitates diagnosis Long duration with bupivacaine (1 2cc total) Bridges gap with onset of CS

Should I Anesthetize the Skin? Local anesthetic not necessary or recommended More painful Limits feedback on accuracy of needle placement Ethyl chloride spray not recommended KEY: Get needle through skin quickly and deliberately

Which Corticosteroid Should be Used? No large RCTs comparing various preparations American College of Rheumatology Survey 5 Triamcinolone acetonide (Kenalog) in the West Methylprednisolone (Depo Medrol) in the East Both agents comparable for SA shoulder injection 6 Both may have less chance of post injection flare

Body Area Specific Location Corticosteroid Dosing Recommendation (Methylprednisolone equivalent) Shoulder Subacromial 40mg Glenohumeral joint Acromioclavicular joint 40 80mg 20mg Knee Intra articular 40 80mg Hip Pre patellar bursa Pes anserine bursa Greater trochanteric bursa/area General rule for methylprednisolone equivalent: 120mg in 1day 160mg in 4 weeks 20 40mg 20mg 20 40mg

Process of Drawing up Medication Open 10cc syringe and attach 18 gauge needle Open medication vials and wipe tops with chlorhexidine Draw medication into syringe; start with multi dose Cap 18 gauge needle but don t remove from syringe Open gauze and bandage, set near patient

Ready For Procedure Pre procedure checklist imed Consent Out of OR Time Out Note Supplies prepared and near patient Marking injection site Sterile prep No touch technique

Retractable pen Marking the Site

Sterile Prep Chlorhexidine over iodine 7 Must be mechanical scrub 2 swabs, 30 seconds each Silver dollar area

No Touch Technique Use final prep to confirm location & hand placement Non sterile gloves Indentation remains

Intra articular Knee Injection Indications Approach Patient Positioning Procedure Checklist

Do I Have a Good Indication for a Knee Aspiration and/or Injection? OA ACR conditionally recommends 8 AAOS inconclusive 9 Degenerative meniscus tear Known inflammatory disease with exacerbation Question of inflammatory disease needing confirmation of crystals Avoid in younger patients/those with normal cartilage

Approach to Knee Injection Flexed Knee Anteromedial joint line Anterolateral joint line Extended Knee Lateral midpatellar Superolateral patellar

Accuracy Review 10 12 Flexed Knee Anterolateral joint line 67 71% Anteromedial joint line 72 75% Extended Knee Lateral midpatellar 85 93% Superolateral patellar 87 91% Improved accuracy Effusion present Provider experience Recommend when starting out to pick one technique and use the same approach every time

Sagittal Knee `

Axial Knee

Recommendations 1 st choice Superolateral patellar or lateral midpatellar Improved accuracy Potentially less painful Alternate Anterolateral or anteromedial joint line When body habitus limits landmarks in extension Severe PF OA with large lateral patellar osteophytes

Patient Positioning Supine Bridge from pelvis to ankle Maximal tolerated hyperextension* Point toes and patella to ceiling Keep quadriceps relaxed (may require additional person to stabilize the foot) Elevate patient to place entry site at eye level

Procedure 1. Identify the upper 1/3 of patella 2. Displace and tilt lateral edge of patella 3. Find entry point: soft indentation just posterior to lateral patellar edge 4. Needle entry: 1. Perpendicular to femur 2. Parallel to ground

Procedure 1. Identify the upper 1/3 of patella 2. Displace patella lateral and tilt lateral edge up 3. ID entry point: soft indentation just posterior to lateral patellar edge 4. Needle entry: Perpendicular to femur + parallel to ground 5. Insert needle quickly through skin, then slowly advance through synovium (0.5 to 1 in)

Knee Injection Summary: Superolateral or lateral midpatellar approach Positioning Maximal hyperextension Toes to ceiling Relax quads Eye level Procedure Upper 1/3 of patella Displace and tilt Perpendicular to femur Parallel to ground

Subacromial Shoulder Injection Indications Approach Patient Positioning Procedure Checklist

Do I Have a Good Indication for Subacromial Injection of the Shoulder? Impingement Syndrome/SA bursitis Rotator cuff tendinitis/partial thickness tear Failed conservative management Inoperable full thickness rotator cuff tear Rotator cuff arthropathy Get both SA and GH areas Not indicated for primary GH OA No connection unless full thickness tear

Subacromial Injections

Approach Posterior Lateral

Patient Positioning Patient seated Arm hanging at side, relaxed Provider stands behind patient Injection site at eye level

1. Identify anterior and posterior acromion 2. Note angle of acromion 3. Find entry point: 1 cm inferior and medial to posterior corner 4. Needle entry: Parallel to acromion angle Saggital plane 5. Insert needle 1 1.5 in. Tip under mid to anterior acromion Procedure

Troubleshooting Always aspirate before injecting If resistance encountered: First, rotate needle 180 degrees Next, withdraw few millimeters Finally, withdraw a few more millimeters and redirect slope of needle by 5 10 degrees

Documentation Requirements See handout

Synovial Fluid Analysis Purple top tube Cell count and differential Crystal analysis Original syringe with cap Gram stain and culture Label each tube Patient name SSN Date/time collected Location ( Right knee ) Order number

Summary Recommendations 21 gauge 1.5 inch needle with 10cc syringe Medications (can be used for both procedures): 1cc = 40mg methylprednisolone or equivalent 2cc 0.1% lidocaine 2cc 0.5% bupivicaine Do not anesthetize the skin Prep skin with chlorhexidine Use the no touch technique Position patient with entry site at eye level Use same approach for each procedure

1. Geirsson AJ, Statkevicius S, Víkingsson A. Septic arthritis in Iceland 1990 2002: increasing incidence due to iatrogenic infections. Ann Rheum Dis 2008; 67:638. 2. Gaffney K, Ledingham J, Perry JD. Intra articular triamcinolone hexacetonide in knee osteoarthritis: factors influencing the clinical response. Ann Rheum Dis 1995; 54:379. 3. Kirschke DL, Jones TF, Stratton CW, et al. Outbreak of joint and soft tissue infections associated with injections from a multiple dose medication vial. Clin Infect Dis 2003; 36:1369. 4. Motamedifar M, Askarian M. The prevalence of multidose vial contamination by aerobic bacteria in a major teaching hospital, Shiraz, Iran, 2006. Am J Infect Control 2009; 37:773. 5. Centeno LM, Moore ME. Preferred intraarticular corticosteroids and associated practice: a survey of members of the American College of Rheumatology. Arthritis Care Res 1994; 7:151. 6. Mod Rheumatol. 2009;19(2):147 50. doi: 10.1007/s10165 008 0137 x. Epub 2008 Nov 22. need full citation PMID 19023644 7. Mimoz O, Karim A, Mercat A, et al. Chlorhexidine compared with povidone iodine as skin preparation before blood culture. A randomized, controlled trial. Ann Intern Med 1999; 131:834. 8. Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 update. American College of Rheumatology Subcommittee on Osteoarthritis Guidelines. Arthritis Rheum. 2000 Sep;43(9):1905 15. 9. Brown GA. AAOS clinical practice guideline: treatment of osteoarthritis of the knee: evidence based guideline, 2nd edition. J Am Acad Orthop Surg. 2013 Sep;21(9):577 9. 10. Hermans J, Bierma Zeinstra SM, Bos PK, Verhaar JA, Reijman M. The most accurate approach for intra articular needle placement in the knee joint: a systematic review. Semin Arthritis Rheum 2011;41:106 115. 11. Jackson DW, Evans NA, Thomas BM. Accuracy of needle placement into the intra articular space of the knee. JBJS 2002; 84(9):1522 7. 12. Maricar N, Parks MJ, Callaghan MJ, et al. Where and how to inject the knee a systematic review. Semin Arthritis Rheum 2013 Oct; 43(2):195 203.