NEUROPATHOLOGY NEWSLETTER

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2001 ANNUAL MEETING Chicago, IL June 21-24, 2001 The 77th annual meeting of the American Association of Neuropathologists will be held June 21-24, 2001, at the Mart Plaza Hotel in Chicago, IL. On-line registration available Pre-register and save $25 For the first time, on-line registration for the meeting is available on the website, www.aanp-jnen.com. Members registering on-line may use a credit card for payment in a secure environment. The AANP now accepts payment by all major credit cards, including VISA, MasterCard, American Express and Discover. Electronic registration will streamline office procedures by eliminating the need for time consuming re-entry of information into our database. Visit the website, www.aanp-jnen.com, to register electronically. Alternately, you may register by returning the registration form enclosed with this newsletter (also downloadable from the website) to the Secretary-Treasurer. Pre-registration fees through June 14th are $100 for members, $150 for Nonmembers and $30 for Trainees. Late and on-site registrants will be charged an $25 additional processing fee. If you would like to attend the Special Course, please include $125 additional. Also please indicate on the Registration Form if you wish to attend the Reception, and include additional payment ($10 for members/ faculty and $5 for students/ residents/ fellows). Meeting Fees NEUROPATHOLOGY NEWSLETTER American Association of Neuropathologists Volume 12, Number 1 March, 2001 Non-Trainee Nonmember Trainee Member General Registration $100 $150 $30 Special Course $125 $125 $125 Reception $10 $10 $5 1 HOTEL RESERVATIONS The Holiday Inn-Mart Plaza Hotel is located in Downtown Chicago at 350 North Orleans St, just north of the Chicago Loop. The Chicago EL train (Merchandise Mart stop on the Brown Line) allows easy access to the hotel and many visitor attractions. The hotel occupies the upper floors of the Apparel Center. All hotel rooms have voice mail and direct dial phones with computer jacks. A fully equipped fitness center and indoor lap pool are available. Reservations may be made by calling the hotel (312-836-5000), or by faxing the reservation form (enclosed with this newsletter or available for download from the website) to the Mart Plaza Hotel (312-222-9508). If calling, please indicate that you are attending the AANP meeting to qualify for discounted room rates. Reservations must be made no later than May 21, 2001, to guarantee rooms at the special meeting rate. Rates after this date are not confirmed and rooms will be confirmed on a space-available basis only. Special per-night room rates for meeting attendees (excluding state and local taxes): Single or Double occupancy $155 Transportation from airport to hotel may be made by taxi, shuttle or Chicago Rapid Transit EL train (see page 2). IN THIS ISSUE 2001 Annual Meeting Information pages 1-4 Hotel Reservation Information page 1 Airport-Hotel Transportation page 2 Association Notices pages 2, 5, 6 AANP Organization page 2 Highlights of the 2001 Meeting pages 3-4 Future Meetings page 4 Guidelines for Presenters page 6 Enclosures page 6

AIRPORT TRANSPORTATION Transportation between Chicago airports and the Mart Plaza Hotel may be made by taxi, shuttle or train. Rates for travel: To/ From Taxi Shuttle* EL Train One-Way One-Way/Rd Trip One-Way O Hare $35 $19/ $34 $1.50 Midway $25 $14/ $25 $1.50 *Price before special $2 off coupon provided by Airport Express included in this mailing. Additional coupons may be requested from the Secretary-Treasurer. CHICAGO--the Windy, Second City An International City Chicago is one of the world's greatest tourist destinations, with millions visiting each year to enjoy its architecture, museums, theaters, concerts, restaurants, shopping, sporting events and unique neighborhoods. Many of Chicago s major attractions, including the Sears Tower, the Magnificent Mile, the Navy Pier, the House of Blues, the Art Institute and Symphony Center, are only a short ride or walk from the hotel. There are several websites devoted to exploring Chicago that you may want to visit as you plan your trip to the area: www.chicago.il.org/ www.ci.chi.il.us/ www.uchicago.edu/docs/chicagoguide/ home.digitalcity.com/chicago/ UPDATE YOUR MEMBERSHIP INFORMATION ON-LINE You can easily update your membership data online. Please click on Members, click here to update your information link after entering the on-line directory. Alternately, please send or fax your new address, phone, fax, and e-mail address directly to the Office of the Secretary-Treasurer. SPECIAL THANKS Many thanks to Tim Wilson at Allen Press for all his efforts in making the electronic abstract submission, on-line directory and secure online meeting registration possible. NEUROPATHOLOGY NEWSLETTER VOL. 12, NUMBER 1 MARCH 2001 American Association of Neuropathologists, Inc. Office of the Secretary-Treasurer Department of Laboratory Medicine and Pathology Mayo Clinic, 200 First St SW Rochester, MN 55905 Phone 507-284-3394, FAX 507-284-1599 E-mail aanp@mayo.edu Home page www.aanp-jnen.com OFFICERS Stephen J. DeArmond, President Peter C. Burger, Vice-President Dennis W. Dickson, President-Elect Raymond A. Sobel, Vice-President-Elect Clayton A. Wiley, Vice-President for Professional Affairs Joseph E. Parisi, Secretary-Treasurer Mark L. Cohen, Assistant Secretary-Treasurer OTHER EXECUTIVE COUNCIL MEMBERS Mauro C. Dal Canto Bernardino Ghetti Michael N. Hart Suzanne S. Mirra Jeannette J. Townsend John Q. Trojanowski COMMITTEE CHAIRS Awards - George Perry Constitution - Thomas J. Montine Membership - Jonathan D. Fratkin Professional Affairs - Clayton A. Wiley Program - Jeffrey A. Golden ARCHIVIST Richard Laverne Davis COUNCILORS TO THE INTERNATIONAL SOCIETY OF NEUROPATHOLGY Mauro C. Dal Canto Hannah Chase Kinney David N. Louis Daniel P. Perl William O. Whetsell, Jr. OFFICIAL JOURNAL Journal of Neuropathology and Experimental Neurology Michael N. Hart, Editor Eileen S. Healy, Managing Editor Email jnen@pathology.wisc.edu NEWSLETTER EDITOR Joseph E. Parisi 2

ANNUAL MEETING INFORMATION Special Course (Thursday, June 21) The special course for the 2001 meeting, entitled Developmental Neurobiology, has been organized by President Stephen J. DeArmond. The Course will provide an update on the molecular biology and cell biology of nervous system development and differentiation and to discuss relevant clinical disorders as related to abnormalities of development. An outstanding roster of speakers has been assembled and ample time for questions and discussion will be available. The program will include the following topics and lecturers: Patterning of CNS & Axon Guidance Dennis D. O Leary (San Diego, CA) Molecular Control of Neuronal Migration Thomas Curran (Memphis, TN) CDC kinase and Neurodegeneration Li-Huei Tsai (Boston, MA) Molecular Mechanism of Forebrain Development Jeffrey A. Golden (Philadelphia, PA) Neurotrophins Window to Neuronal Functions Louis F. Reichardt (San Francisco, CA) Transcriptional Control of Neuronal Survival and Differentiation Eric Huang (San Francisco, CA) Developmental Abnormalities of the Nervous System in Human & Animal Models Harvey B. Sarnat (Seattle, WA) Scientific Sessions (June 22-23) Concurrent platform and poster sessions will be held all day Friday and Saturday, June 22-23. The program will provide up-to-date developments in all areas of experimental, research and practical neuropathology. Poster sessions will run from 8:00 am to 5:30 pm. Although no poster discussion sessions will be held this year, poster presenters will be asked to be present at designated times to facilitate discussion with other interested attendees. Members are responsible for disseminating this information to their residents, fellows and guests. Business Meeting (12 noon, Friday & Saturday, June 22 & 23) The annual business meeting will be held at 12 noon on both Friday, June 22 and Saturday, June 23. The 2001 Meritorious Service Awards to Neuropathology will be presented on Friday June 22. Sears Tower Reception (Friday evening, June 22) We are pleased to announce that the annual reception for meeting attendees and their guests will be held at the Top of the Tower on the 99th floor of the Sears Tower on Friday evening. Soaring 1,454 feet into the air with 110 stories, the Sears Tower competes with the Petronas Towers in Malaysia for the title of Tallest Building in the World. On a clear night, you can see out 40 or 50 miles and into four states: IL, IN, MI, and WI. Hors d oeuvres and a cash bar will be available. Admission is $10 for faculty/staff and $5 for students/ residents/ fellows. Those wishing to attend may submit payment with the pre-registration form, or may purchase tickets at the meeting. Continuous round-trip shuttle bus transportation between the Mart Plaza hotel and the Sears Tower will be provided. The reception is sponsored in part by generous contributions from Elan Corporation and Oxford University Press. Please note that the reception does not include admission to the Sears Tower Sky Deck Observatory that is open 9 am - 11 pm daily. The cost is $8.50 for adults. Saul R. Korey Lecture (11 AM, Saturday, June 23) Professor Paul Kleihues, Lyon, France, has been selected as the next Saul R. Korey lecturer. Dr. Kleihues lecture, entitled Molecular Biology of Brain Tumors, promises to provide an up-to-date review of this important topic. 3

ANNUAL MEETING INFORMATION Diagnostic Slide Session (8 PM, Saturday, June 23) Slides and protocols for the Annual Diagnostic Slide Session may be purchased for $40 in U.S. currency. Foreign checks, including Canadian, must be issued through an American Bank with a proper routing number. Please make checks payable to Diagnostic Slide Session and mail to: Leroy R. Sharer, M.D. Department of Pathology New Jersey Medical School 185 South Orange Avenue Newark, NJ 07103 Phone 973-972-4770 Fax: 973-972-5933 Slide sets are limited to one per person. The protocols will be sent from New Jersey, and the slides from Boston, on or about May 7. Slide delivery before the meeting for any order received after May 14, 2001 cannot be guaranteed. If payment is made by an institutional check, please make certain that the recipient s name is listed on the check or the accompanying paperwork. The Association certifies the Diagnostic Slide Session as a continuing medical education activity and meets the criteria for 3 credit hours in Category 1 of the Physician s Recognition Award of the American Medical Association. Presidential Symposium (8 AM, Sunday, June 24) Dr. Stephen DeArmond s Presidential Address, entitled Mechanisms of Degeneration in Prion Diseases, will be featured at the Presidential Symposium. In addition, Dr. Cheryl Wellington (Vancouver, BC) will speak on Huntingtin: A Fulcrum between Life and Death, and Dr. Ralph A. Nixon (New York, NY) on Lysosomal Mechanisms of Neurodegeneration. As part of the Symposium, the Matthew T. Moore Distinguished Lecture, entitled Receptormediated Neurodegeneration, will be presented by Dr. Dennis W. Choi (St. Louis, MO). During the Symposium, annual AANP awards, including the Rubinstein Award for the best paper in neuro-oncology, the Weil Award for the best paper in experimental neuropathology and the Moore Award for the best clinicopathological correlation will be presented. CME Credit The American Association of Neuropathologists is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to sponsor continuing medical education for physicians. The Association certifies the Special Course as a continuing medical education activity and meets the criteria for 7 credit hours in Category 1 of the Physician s Recognition Award of the American Medical Association. Further, the Association certifies the Scientific Sessions, the Korey Lecture, the Diagnostic Slide Session and the Presidential Symposium as continuing medical education activities that meet the criteria for 19 credit hours in Category 1 of the Physician s Recognition Award of the American Medical Association. Activity CME Credit Hours Special Course 7 Scientific Sessions 12 Korey Lecture 1 Dx Slide Session 3 Presidential Symposium 3 Total 24 Attendees should claim credit only for those activities attended. FUTURE MEETINGS 2002: Marriott Denver City Center Denver, CO June 20-23, 2002 2003: Wyndham Orlando Resort Orlando, FL June 19-22, 2003 AANP Payments by Charge Card All Major Cards NOW Accepted! The AANP now is able to accept payment for dues and meeting registrations by ALL MAJOR Charge Cards, including VISA, MasterCard, American Express and Discover. This should be especially good news to our overseas members who previously were required to make payment by costly international money orders and bank checks. 4

ASSOCIATION NOTICES ELECTRONIC SUBMISSIONS An Unqualified Success! Electronic submission for abstracts this year met with enthusiastic approval of members many thanks to Dr. Golden for all his efforts. A total of 225 abstracts have been received; of these, 160 were submitted electronically and the remaining 65 by mail. The Program Committee currently is busy reviewing the submitted abstracts and assembling what promises to be an exciting scientific program. Two platform sessions will be conducted concurrently and there will be one poster session each day. Abstracts will be published in the May, 2001 issue of the Journal of Neuropathology and Experimental Neurology and the program will be posted on the AANP web site (www.aanp-jnen.com) by midlate March. MEMBERSHIP DIRECTORY On-Line Directory Up and Running! The Online Directory has become a reality! Please note that only members who ticked the YES box on their 2001 Dues statement are included in the online directory. Members who ticked the NO box or left it blank are not included. If you are not currently listed and would like to be included, please click on the Members, click here to update your information link after entering the on-line directory and indicate that change when prompted. Members may also communicate any changes of addresses, phone, fax and e-mail by clicking on this button. Maintaining up to date mailing information assures you of receiving AANP mailings and copies of the JNEN. A printed 2001 directory of members will be sent with the June issue of the Journal of Neuropathology and Experimental Neurology. According to the Association s policy, members who have not paid their 2001 dues will not be listed. DUES UPDATE Included with this mailing is your receipt for payment of your 2001 annual dues. If you did not receive a dues notice or reminder, please contact the Secretary-Treasurer as soon as possible. Please... REGISTER and RESERVE EARLY! SAVE $25 by Pre-registering before June 14th. Late and On-site registrants will be charged $25 additional. (1) REGISTER on-line at www.aanp-jnen.com or by mailing or faxing the enclosed Meeting Registration Form to the Secretary-Treasurer at: American Association of Neuropathologists Office of Secretary-Treasurer Joseph E. Parisi, MD Department of Lab Medicine & Pathology Mayo Clinic 200 First Street SW Rochester, MN 55905 FAX: 507-284-1599 (2) RESERVE your hotel room by contacting the Mart Plaza Hotel by phone (800-833-8624) or by faxing the enclosed Hotel Reservation Form. Please Visit the AANP and JNEN web site, www.aanp-jnen.com, for up-to-the-minute AANP news and information. DEATHS It is with great sadness that we report the deaths of two members of our Association: Mary Jane Aguilar, MD Tucson, AZ Died April 27, 1998 Nathan Malamud, MD San Francisco, CA Died November 20, 2000 5

New Awards Committee Chair Welcome Dr. Perry, Thank you Dr. Crain Welcome to Dr. George Perry, who assumes the role of Chair of the Awards Committee and follows the footsteps of Dr. Barbara Crain who so ably headed the Committee since 1998. The Awards Committee has the daunting task of selecting presentations of exceptional merit for annual AANP awards. PRESENTATION SUGGESTIONS Platform Presentations: No more than 10 minutes of speaking time will be allowed for each platform presentation. This will be followed by a 5 minute time period available for questions and discussion from the audience, with a total of 15 minutes allotted to each presentation at a platform session. Please be aware that Platform chairpersons are instructed to interrupt the speaker, if necessary, to adhere to the time constraints. This will be done (1) to make sure that there is adequate time for questions, and (2) to insure that later speakers in that same platform session have the full time allowance for their presentations. Strict adherence to the time limits and platform schedule also allows members of the audience to move between sessions and catch all presentations in which they are interested. Each platform presentation should include a brief introduction (preferably with the hypothesis clearly stated), a statement of methods, a summary of the data, and a conclusion that states how the current study advances the field. The Program Committee hopes that stimulating dialogue will be generated by each platform presentation. To facilitate audience involvement, presenters should repeat questions from the audience that may not be heard by everyone. The chairperson(s) also may elect to assist by repeating questions from the audience that they feel need clarification. Poster Presentations: The display panels for the poster sessions will consist of 4' x 8' (1.23 x 2.46 m) poster boards mounted horizontally on a pedestal at a convenient viewing level. At the top of your poster, there should be a heading indicating the title, author(s) and institution(s). The lettering for this section should not be less than 2.5 cm (1") high. A copy of the abstract, in large typescript, should be posted in the upper left-hand corner. Studies alluded to in the text must be referenced. Remember that your text and illustrations will be viewed from distances of 3 feet or more. All lettering should be at least 3/8" (~1 cm) high, preferably in bold font. Keep everything as simple as possible. Block lettering may be used to add emphasis and clarity. Captions should be brief and labels few and clear. It is helpful if the sequence to be followed in studying your material is indicated by numbers, letters or arrows. Additional suggestions for effective poster presentations may be found in the following reference: Woolsey JD: Combating poster fatigue: how to use visual grammar and analysis to effect better visual communications. Trends in Neurosciences 12(9): 325-32, 1989. Posters may be mounted by Velcro or push-pins. Please take your own mounting tapes/ push-pins (preferably 5/8" long) to the meeting. Thumb tacks are not adequate to fasten your display to the poster boards. PUSH-PINS WILL NOT BE PROVIDED. NOTICE FOR AUTHORS OF ABSTRACTS: Authors of abstracts that have been published as full length papers are reminded that they are responsible for informing the Secretary-Treasurer s office of this prior to the meeting. Abstracts of previously published papers are not eligible for the Association Awards. ENCLOSURES Annual Meeting Registration Form Hotel Reservation Form Chicago Airport Express $2 off coupon 2001 Annual Dues Receipt 6