Objectives. Challenges of Geriatric Fractures. Faith Trial. Overview. Evidence 3/13/2017

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Challenges of Geriatric Fractures Brian Buck, DO March 3, 2017 31st Annual Geriatric Conference Pearls of Geriatric Care Objectives Identify challenges of osteoporotic bone Describe some of the techniques to improve fracture fixation in geriatric patients Understand the choice of implant in particular geriatric injuries Overview What is the evidence Osteoporosis/Age related changes Goals of surgery Technique considerations Implant considerations Perioperative goals Faith Trial Over 1,000 pts Worldwide Screw fixation vs CHS No difference in re-operation rate Greater risk of AVN/ON in CHS Displaced fx, smokers, basicervical associated c fewer reoperations c CHS Evidence Poor level of evidence Despite large number of patients, little indication in literature driving treatment 1

Osteoporotic fractures Fracture patterns Osteoporosis Osteoporosis Bone mineralization Bone strength Bone geometry Bone healing Age related geometry changes Effect on bone healing Prolonged Decreased healing capacity Mineralization/cellular differences Nonunion/malunion 2

Considerations Define the injury Discuss risks/benefits of fixation v nonop Goals of surgery Perioperative optimization Minimize morbidity Maximize outcome Risks/benefits Realistic discussion c patient/family Functional results Ability to use limb/ambulate Return to ADL Return to home Goals of surgery Promote bone healing Restoration of function Consideration for arthroplasty Length, rotation, alignment Intra-articular involvement Open fracture Techniques to improve healing Minimally invasive Bone impaction Buttress fixation Bone augmentation Lever-arm modification Biologically friendly Preserve blood supply Preserve fracture hematoma Improved union rates Length/rotation/alignment Articular joint reconstruction 3

Impaction Buttress fixation Bone augmentation Allograft TCP BMPs PDGFs PTH Lever-arm Implants Medullary nails Fixed angle devices Nonlocking and locking plates 4

Implants Medullary nail Bridge constructs Implant coating Arthroplasty Periprosthetic fractures Load sharing Immediate WBAT Biologically friendly Relative stability c secondary bone healing Nonlocking plates Locking technology Bridge plating 5

Arthroplasty Periprosthetic fracture Early motion Immediate weight bearing Realistic expectations Communication Often require fixation/revision TJA Difficult problems/difficult solutions Poor bone stock/require extensive procedures Perioperative optimization Team approach Assess risk Physiologic parameters Timing of surgery Team Approach Co-management between ortho/geriatrician/hospitalist LOS Post-op complications 1 yr mortality Delerium Team Approach Improves communication National/hospital standardization/guidelines improve care Mitigate complications 6

Risk Assessment Comorbidities Dementia COPD CHF Cancer Previous MI Risk Assessment Gender Nutritional status Admitting cognitive status Risk Assessment ACC/AHA guidelines ASA Score Not designed to assess surgical risk However, studies have correlated ASA with outcome Risk of perioperative cardiac events Recent MI Decompensated CHF Optimizing patient Oxygenation Fluid/electrolyte balancing Pain management Medication elimination Bowel/bladder focus Early mobilization Delerium treatment/prevention Timing of surgery As early as possible when it is as safe as possible 7

Minimize morbidity VTE prophylaxis VTE prophylaxis Anesthetic considerations Treatment of anemia Pain management Address cognitive deficits Up to 5 wks LMWH for HFS (Chest) Not indicated for fractures below the knee Pelvis-->knee ** Anesthesia General/regional Beta blockade Normothermia Safe/efficient operating experience Transfusion Antibodies (3% gen, 25% in prev transf) Anemia Preoperative anemia LOS 1 year mortality Anemia Estimated EBL 1 L hip fracture Predictors of blood loss Anticoagulants Intraoperative hypotension GI bleed Anemia considerations Perioperative anemia 550 pts Hb < 12 mg/dl Longer LOS Higher readmission rate 8

Optimal Hb levels? Pain management Optimal Hb 10 mg/dl CV complications 2% vs 10% Mortality 0% vs 8% Debate of over vs under medication Importance of physiologic parameters Delerium prevention Delerium Maximize outcome Most important factors predicting mortality following hip fracture Concomitant illnesses Delerium on admission Postoperative mobilization Rehabilitation Fall risk Postoperative mobilization WBAT for all UE fxs WBAT for all hip fractures Ideally, WBAT for all LE fx Realistically, 6-8 wks of protected WB for LE fx/intra-articular fxs 6wk/3mo/1 yr mortality improvement Rehabilitation Improves nutritional status Strength/stamina improvements Fall/fracture prevention strategies Depression Osteoporosis treatment 9

Fall risk Exercise decreases fall risk Ca+2/Vit D Medication review and changes Clutter elimination/household changes Summary Establish goals of treatment and discuss with patient/family Familiar with techniques to improve union Utilize biologically friendly procedures/load sharing implants Optimize patients Early motion and weight bearing 10