The Aging Digestive System

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The Aging Digestive System shows significant senescence in old age: less saliva food less flavorful, harder swallowing ~half of those over 65 yrs wear dentures gastric mucosa secretes less acid reduces absorption of Calcium iron, zinc and folic acid gastric mucosa secretes less intrinsic factor reduces absorption of vitamin B12 leads to pernicious anemia Heartburn becomes more common most common digestive complaint of older people is constipation due to: less muscle tone weaker colon peristalsis reduced sensitivity to neurotransmitters less fiber & water in diet less exercise activity of liver, gall bladder and pancreas are reduced only slightly in old age 1

Digestive Problems 1. Choking food in air passages usually meats, hot dogs, grapes, carrots, hard candy, popcorn, peanut butter may not be able to make a sound DON T hit on back 2. Vomiting symptom of many diseases waves of reverse peristalsis if severe may empty duodenum as well rest and drink small amounts of fluids guard against massive fluid loss 3. Bulemia self induced vomiting may cause damage and infection of esophagus, pharynx, or salivary glands erosion of teeth, more dental caries esophagus may rupture or tear 4. Diarrhea frequent loose watery stool intestinal contents moving too fast for fluid absorption to occur main danger is fluid loss also upsets acid/base balance 5. Constipation caused by: lifestyle inadequate water input lack of physical activity side effect of medication controlled by increase in fiber, prunes, laxatives attracts water softens stool 2

Colonic Irrigation alternative medical practice potentially harmful unneccessary can rupture the intestine frequent use of laxatives and enemas: can lead to dependency upset body s fluid balance mineral oil can interfere with absorption of fat soluble vitamins 6. Belching results from swallowed air carbonated drinks and chewing gums can contribute occasionally can be a sign of a more serious disorder: gall bladder pain, colonic distress eat slowly, chew thoroughly relax while eating 7. Hiccups repeated spasms of diaphragm may be triggered by eating or drinking too fast 8. Gas large intestine generates 7-10 L of gas/day and normally we expel ~500ml of gas/day the rest is reabsorbed most is odorless 1% are volatile gasses high carb foods known to produce excess gas 9. Heartburn (& gastroesophageal reflux disease) cardiac sphincter doesn t close properly affects 50% of US, esp white males 3

eat or drink too much clothing too tight cure: eat small meals drink liquids 1 hr before or 1 hr after meal don t lie down or bend over lose weight if overweight don t smoke use antacids but sparingly 10. Peptic Ulcers a lesion of stomach or duodenum caused by acids or pepsin duodenal ulcers are the most common perforated ulcer extend through entire wall of GI tract caused by: bacterial infection, Helicobacter pylori, is important cause of most ulcers in all patients with duodenal ulcers in 80% of patients with gastric ulcers probably disrupt mucosal barrier use of some antiinflammatory drugs disorders that cause excessive gastric secretions reduced mucosal defense diet therapy used to be main cure, now antibiotics also advised to stop smoking and avoid alcohol and caffeine 11. Celiac Disease chronic disorder in which the mucosa of small intestine is damaged by ingestio fo certain cereal grains, eg. wheat, barley, rye, & oats disease 1 st reported in second century by Aretaeus of Cappadochia these grains have large amounts of a protein, =gluten, causes loss of villi & brush border, and increased numbers of WBC s leads to inadequate intestinal absorption symptoms: diarrhea, weight loss, abdominal distension and bloating and weakness due to genetic and environmental factors patients with such sensitivity must adhere to gluten-free diet substitute: corn, millet, buckwheat, sorghum & rice 4

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