V-Go : Simple to start, easy to use

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V-Go : Simple to start, easy to use Patient Start Guide Make multiple daily insulin shots a thing of the past. Take control with V-Go. V-Go Customer Care personalized 1-on-1 support for you Call 1-866-881-1209 today! Visit www.startvgo.com

V-Go changed my life immensely. It makes it so much easier to control my A1c. V-Go user Day 1: Start right q Do not take any other insulin shots in combination with V-Go unless directed by your healthcare professional q Wear V-Go any place where insulin can be injected and that remains flat when you sit, stand, or lie down q Once V-Go is applied, make sure to press the Start Button until it locks to begin the flow of insulin Start on V-Go, stay on track Learning something new can be challenging. We have the support you need to start and stay on V-Go successfully. q Use the 2 Bolus Delivery Buttons to deliver the prescribed amount of insulin (1 click = 2 Units) at mealtime q After a full 24 hours, replace V-Go with a new filled V-Go. If V-Go falls off, replace it with a new filled V-Go immediately q If you have any questions, contact V-Go Customer Care (VCC) Visit www.startvgo.com to view stories from patients like you, educational videos, FAQs, and personalized support Get started on V-Go today and experience simplified insulin delivery you apply like a patch. Visit www.startvgo.com for more information and support to get started on V-Go. 2 3

V-Go is simple, all-in-one insulin delivery that fits your lifestyle V-Go helps you because it delivers insulin much like your body is supposed to.* It helps you manage type 2 diabetes by delivering a steady rate of insulin 24 hours a day (basal).* V-Go also enables you to give yourself a dose of insulin at mealtimes (bolus). INSULIN DELIVERY WITH V-Go 1 fast-acting insulin, 1 application daily Insulin delivery you apply like a patch Choosing a V-Go application site Apply V-Go vertically to the back of your arm or thigh, or horizontally to your abdomen or back (avoiding folds of skin, muscle, or bone) Avoid areas with lots of hair or shave them Be sure you can easily operate V-Go before applying Fill, Wear, Go Fill V-Go with fast-acting insulin Apply it to the the back of your arm, abdomen, back, or thigh Push the top button to begin 24-hour insulin delivery Steady rate of insulin 24/7 (basal) On-demand dosing at mealtimes (bolus) On-demand dosing for snacks (bolus) Push the side buttons to administer mealtime insulin Back of the arm Where to place your V-Go With V-Go, you can help control your blood sugar with just 1 fast-acting insulin and 1 application daily. This means eliminating the need for multiple daily injections to help improve blood sugar control throughout the day and night and at mealtimes. 1-4 Abdomen or back, avoiding folds of skin, muscle, or bone * If you follow the V-Go Instructions for Patient Use. A U-100 fast-acting insulin should be used with V-Go. Humalog (insulin lispro [rdna origin] injection) and NovoLog (insulin aspart [rdna origin] injection) have been tested by Valeritas, Inc. and found to be safe for use in the V-Go Wearable Insulin Delivery Device. Humalog is a registered trademark of Eli Lilly and Company. NovoLog is a registered trademark of Novo Nordisk A/S. Thigh 5

V-Go Customer Care with you from Day 1 and beyond From the moment you begin V-Go, V-Go Customer Care (VCC) is with you every step of the way. Enroll at 1-866-881-1209. VCC offers you a wide range of benefits. Online V-Go resources when you need them visit www.startvgo.com There you ll find: 1-on-1 partner You will have a dedicated V-Go Partner to provide personalized support How-to Fill, Wear & Go videos V-Go Life Self-Management Program Starting V-Go Offers step-by-step instruction by phone or video chat on how to Fill, Wear & Go with V-Go V-Go Live weekly demo Webinar Reimbursement support including V-Go instant savings program Reimbursement help Provides expert personalized insurance guidance and benefits investigation Real patient success stories Downloadable materials Quick reference guide Blood sugar log Pharmacy support Makes obtaining V-Go and using the instant savings card easy Frequently asked questions (FAQs) Instructions for Patient Use Follow-up calls Support you with regular calls over the first 90 days V-Go Life Self-Management Program Provides online access to practical information about diabetes and V-Go Getting Started With V-Go Fill this worksheet out with your doctor. Time to apply a new V-Go each day: At mealtimes, use the amount of insulin prescribed by your doctor (1 click = 2 Units). How many times will I click the How many insulin V-Go Bolus Delivery Button? units will there be? Breakfast clicks = Units Lunch clicks = Units Dinner clicks = Units Snack clicks = Units No matter the question,* V-Go Customer Care is here to provide you with the support you need. Make sure to keep track of the number of clicks you give yourself at each meal. If you lose count, STOP clicking, monitor your blood glucose, and follow the plan agreed upon with your doctor or healthcare professional. Follow-up appointments: Follow-up appointment with your doctor (1st) Follow-up appointment with your doctor (2nd) *Valeritas does not give medical advice about insulin therapy. Discuss all medical therapies with your healthcare professional. 7

With V-Go, the quality of my day is greatly increased. I m not worried about taking my insulin. Jim, V-Go user 9/10 9 out of 10 users were satisfied with how V-Go fit into their lifestyle 5 If you ever have questions, be sure to call V-Go Customer Care at 1-866-881-1209 Important Risk Information: If regular adjustments or modifications to the basal rate of insulin are required in a 24-hour period, or if the amount of insulin used at meals requires adjustments of less than 2-Unit increments, use of the V-Go Wearable Insulin Delivery Device may result in hypoglycemia. The following conditions may occur during insulin therapy with V-Go: hypoglycemia (low blood glucose) or hyperglycemia (high blood glucose). Other adverse reactions associated with V-Go use include skin irritation from the adhesive pad or infections at the infusion site. V-Go should be removed before any magnetic resonance imaging (MRI) testing. References: 1. Kapitza C, et al. J Diabetes Sci Technol. 2008;2(1):40-46. 2. Omer A, et al. Poster presented at: American Diabetes Association 73rd Scientific Sessions; June 21-25, 2013; Chicago, IL. Abstract 980-P. 3. Rosenfeld CR, et al. Endocr Pract. 2012;18(5):660-667. 4. Grunberger G, et al. Poster presented at: American Diabetes Association 73rd Scientific Sessions; June 21-25, 2013; Chicago, IL. Abstract 985-P. 5. Data on File. Valeritas, Inc. August 16, 2016. V-Go is a registered trademark of Valeritas, Inc. ART-750 Rev: B 08/2017 2017 Valeritas, Inc. www.startvgo.com