A Data Use Guide ESTIMATING THE UNIT COSTS OF HIV PREVENTION OF MOTHER-TO-CHILD TRANSMISSION SERVICES IN GHANA. May 2013

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May 2013 ESTIMATING THE UNIT COSTS OF HIV PREVENTION OF MOTHER-TO-CHILD TRANSMISSION SERVICES IN GHANA A Data Use Guide This publication was prepared by Andrew Koleros of the Health Policy Project. HEALTH POLICY P R O J E C T

Suggested citation: Koleros, Andrew. 2013. Estimating the Unit Costs of HIV Prevention of Mother-to-Child Transmission Services in Ghana. Washington, DC: Futures Group, Health Policy Project. The Health Policy Project is a five-year cooperative agreement funded by the U.S. Agency for International Development under Agreement No. AID-OAA-A-10-00067, beginning September 30, 2010. The project s HIV-related activities are supported by the U.S. President s Emergency Plan for AIDS Relief (PEPFAR). It is implemented by Futures Group, in collaboration with CEDPA (CEDPA is now a part of Plan International USA), Futures Institute, Partners in Population and Development, Africa Regional Office (PPD ARO), Population Reference Bureau (PRB), RTI International, and the White Ribbon Alliance for Safe Motherhood (WRA).

Estimating the Unit Costs of HIV Prevention of Mother-to-Child Transmission Services in Ghana MAY 2013 This publication was prepared by Andrew Koleros 1 of the Health Policy Project. 1 Futures Group. The information provided in this document is not official U.S. Government information and does not necessarily represent the views or positions of the U.S. Agency for International Development.

CONTENTS Abbreviations... v Introduction... 1 A data use guide... 1 Purpose of this guide... 1 Costs for Six Types of Clients... 1 Using Study Results for National Planning and Budgeting: Estimating the total annual cost of the PMTCT program... 4 Estimating PMTCT costs for the National HIV & AIDS Strategic Plan 2011 15... 7 PMTCT Scale-Up Plan... 9 Using Study Results for Resource Mobilization and Allocation: Global Fund applications and PEPFAR Country Operational Plans... 10 References... 13 iii

iv

ABBREVIATIONS AIDS acquired immune deficiency syndrome ANC antenatal care ART antiretroviral therapy ARV antiretroviral CHPS Community-based Health Planning Services COP Country Operational Plan DBS dried blood spot (method) EID Early Infant Diagnosis EPP Epidemic Projection Package GAC Ghana AIDS Commission GFATM Global Fund to Fight AIDS, Tuberculosis and Malaria GHS Ghana Health Services HAART highly active antiretroviral therapy HIV human immunodeficiency virus HPP Health Policy Project HTC HIV testing and counselling M&E monitoring and evaluation NACP National AIDS/STI Control Programme, Ghana NSP National Strategic Plan on HIV and AIDS 2011 2015 OI opportunistic infection PEPFAR U.S. President s Emergency Plan for AIDS Relief PMTCT prevention of mother-to-child transmission STI sexually transmitted infection UNAIDS Joint United Nations Programme on HIV and AIDS UNICEF United Nations Children s Fund USAID United States Agency for International Development WHO World Health Organization WTO World Trade Organization v

vi

INTRODUCTION A Data Use Guide In response to the HIV epidemic, the Government of Ghana has gradually scaled up effective HIV interventions based on locally generated data. Good estimates, projections, and planning are dependent on having accurate knowledge about costs. To support the evidence base for the national HIV Prevention of Mother-to-Child Transmission (PMTCT) program, Ghanaian government agencies, the U.S. Agency for International Development (USAID), and the USAID Health Policy Project conducted a joint study in 2011 to estimate the unit costs of providing PMTCT services in Ghana. The costing study focused on services that are included in the current National PMTCT Guidelines and are delivered by health facilities, such as HIV testing and counseling, antiretroviral (ARV) prophylaxis and/or therapy for HIVpositive pregnant women, and postpartum care for HIV-positive mothers and their HIV-exposed infants. The study analyzed unit cost, defined as the cost of delivering PMTCT services to a woman and her infant from pregnancy through the recommended period of postpartum care, as well as the average costs and drivers of costs within the national PMTCT program. Purpose of This Guide The final report of this study provides useful information for national program planners, donors, and other stakeholders. However, it does not include specific operational details on how these different stakeholders can use the study results for their individual planning, budgeting, and resource mobilization and/or allocation purposes. During the February 2012 national meeting on validating the study results, stakeholders requested further guidance on how they can practically use study results for these individual processes. This guide summarizes the key findings from the study and provides specific details on how study results can best be used to inform the evidence base for the Ghana PMTCT program. COSTS FOR SIX TYPES OF CLIENTS The most representative indicator of national costs is an average cost for each type of client served within the PMTCT program. The study identified six types of clients: 1. HIV-negative women 2. HIV-positive women on ARV Prophylaxis (Option B) 3. HIV-positive women on ARV treatment 4. HIV-exposed infants who are HIV positive at six weeks 5. HIV-exposed infants who are HIV positive at six months 6. HIV-exposed infants who are HIV negative or HIV positive at 12 months Based on the study findings, Table 1 provides a summary of overall costs for each type of PMTCT client, disaggregated by type of cost. 1

Estimating the Unit Costs of HIV Prevention of Mother- To-Child Transmission Services in Ghana Table 1. Average Unit Costs of PMTCT Services, by type of client and by type of cost (US$) HIV-negative women HIV-positive women on ARV Prophylaxis (Option B) HIV-positive women on ARV treatment HIV-exposed infants who are HIV+ at six weeks HIV-exposed infants who are HIV+ at six months HIV-exposed infants who are HIV- or HIV+ at 12 months Cost % of Cost Component % of Total Cost Cost % of Cost Component % of Total Cost Cost % of Cost Component % of Total Cost Cost % of Cost Component % of Total Cost Cost % of Cost Component % of Total Cost Cost % of Cost Component % of Total Cost DIRECT COSTS 84.04 100% 100% 816.94 100% 75% 1,281.94 100% 83% 43.46 100% 100% 74.12 100% 100% 101.40 100% 100% Staff 39.50 47% 47% 155.22 19% 14% 153.83 12% 10% 11.30 21% 21% 19.27 26% 26% 27.38 27% 27% Drugs 9.24 11% 11% 482.00 59% 44% 589.69 46% 38% 6.52 27% 27% 11.12 15% 15% 11.15 11% 11% Laboratory testing 34.46 41% 41% 171.56 21% 16% 461.50 36% 30% 25.21 51% 51% 42.99 58% 58% 61.86 61% 61% Medical consumables and supplies 0.84 1% 1% 8.17 1% 1% 76.92 6% 5% 0.43 1% 1% 0.74 1% 1% 1.01 1% 1% INDIRECT COSTS 0% 0% 271.52 25% 271.52 17% - 0% 0% - 0% 0% - 0% 0% Facility Level - 0% 0% 154.02 100% 14% 154.02 100% 10% - 0% 0% - 0% 0% - 0% 0% Non-client staff time - 0% 0% 6.97 5% 1% 6.97 5% 0% - 0% 0% - 0% 0% - 0% 0% Office equipment - 0% 0% 5.92 4% 1% 5.92 4% 0% - 0% 0% - 0% 0% - 0% 0% Physical infrastructure - 0% 0% 4.13 3% 0% 4.13 3% 0% - 0% 0% - 0% 0% - 0% 0% Transportation costs - 0% 0% 10.93 7% 1% 10.93 7% 1% - 0% 0% - 0% 0% - 0% 0% Public utilities and running - 0% 0% 10.93 7% 1% 10.93 7% 1% - 0% 0% - 0% 0% - 0% 0% costs Maintenance and repair - 0% 0% 53.27 35% 5% 53.27 35% 3% - 0% 0% - 0% 0% - 0% 0% Staff training and volunteers - 0% 0% 0.70 0% 0% 0.70 0% 0% - 0% 0% - 0% 0% - 0% 0% Local medical and other - 0% 0% 58.74 38% 5% 58.74 38% 4% - 0% 0% - 0% 0% - 0% 0% 2

supply costs Vehicle costs - 0% 0% 2.44 2% 0% 2.44 2% 0% - 0% 0% - 0% 0% - 0% 0% General Program - 0% 0% 117.49 100% 11% 117.49 100% 8% - 0% 0% - 0% 0% - 0% 0% Support Planning and program - 0% 0% 2.35 2% 0% 2.35 2% 0% - 0% 0% - 0% 0% - 0% 0% management Centrally managed trainings and - 0% 0% 89.30 76% 8% 89.30 76% 6% - 0% 0% - 0% 0% - 0% 0% supervision Monitoring and evaluation - 0% 0% 19.97 17% 2% 19.97 17% 1% - 0% 0% - 0% 0% - 0% 0% Communication materials - 0% 0% 5.87 5% 1% 5.87 5% 0% - 0% 0% - 0% 0% - 0% 0% TOTAL 84.04 100% 100% 1,088.46 100% 100% 1,553.45 100% 100% 43.46 100% 100% 74.12 100% 100% 101.40 100% 100% 3

Estimating the Unit Costs of HIV Prevention of Mother- To-Child Transmission Services in Ghana USING STUDY RESULTS FOR NATIONAL PLANNING AND BUDGETING: ESTIMATING THE TOTAL ANNUAL COST OF THE PMTCT PROGRAM When using study results to estimate the total cost per year of the PMTCT program, national program planners should choose one of two approaches based on either (1) the six types of PMTCT client; or (2) the costs of an average PMTCT client, taking into account the proportion of HIV-positive clients. This choice will depend on the availability of accurate and reliable program monitoring data. Projecting total annual costs per client type The most accurate measures for projecting annual costs are obtained by projecting the expected number of each type of client per year, based on reliable historical data and assisted by modeling techniques using software packages such as Epidemic Projection Package (EPP)/Spectrum (UNAIDS, 2011). Program planners should project the estimated number of each type of client and apply the unit cost to obtain an annual total. Then they should add the total costs to estimate the total annual cost for the national PMTCT program. Table 2 provides a simplified example of how to estimate these costs. PMTCT client type Table 2. Illustrative example of projecting annual costs per client type* Example of projections from EPP/Spectrum 4 Unit cost from study (US$) Projected annual cost (US$) 2012 2013 2014 2012 2013 2014 HIV-negative women 500,000 550,000 600,000 57.02 28,510,000 31,361,000 34,212,000 HIV-positive women on ARV 5,000 5,500 6,000 738.54 3,692,700 4,061,970 4,431,240 prophylaxis HIV-positive women on ARV 2,500 2,750 3,000 1,054.05 2,635,125 2,898,638 3,162,150 treatment HIV-exposed infants who are 500 550 600 29.49 14,745 16,220 17,694 HIV+ at six weeks HIV-exposed infants who are HIV+ at six 1,000 1,100 1,200 50.29 50,290 55,319 60,348 months HIV-exposed infants who are HIV- or HIV+ at 12 8,000 8,500 9,000 68.80 550,400 584,800 619,200 months TOTAL 35,453,260 38,977,946 42,502,632 *Numbers are not actual program data but are shown here for illustrative purposes only. Projecting cost-specific annual costs per client type To obtain specific costs according to different cost categories, the total projected annual costs can be multiplied by the percentage of each cost category as a function of total cost. For example, Table 1 shows that drug costs account for 44 percent of the total cost of providing PMTCT services to an HIV-positive

Using Study Results for National Planning and Budgeting: Estimating the total annual cost of the PMTCT program woman on ARV prophylaxis. Thus, if the total projected cost of providing PMTCT services to HIVpositive women on ARV prophylaxis is estimated at US$3,692,700 in 2012 as shown in Table 2, the total projected cost of ARV drugs in 2012 is estimated to be: Total Estimated Cost of ARV Drugs in 2012 = US$3,692,700 * 44% = US$1,624,788 Projecting total annual costs per average client Another way to project costs is to calculate an average weighted cost per client, which represents the cost for a typical PMTCT client, based on the client load for each type of client in relation to the total number of clients served. Based on 2010 historical data, the joint study estimated that approximately 98 percent of all pregnant women attending PMTCT services were HIV-negative women; HIV-positive women on ARV prophylaxis accounted for 1 percent of all pregnant women and those on ARV treatment represented an additional 1 percent of all pregnant women. So for every 100 pregnant women attending PMTCT services, based on 2010 data, it is expected that 98 of these women will be HIV negative, one woman will be HIV positive and eligible for ARV prophylaxis, and one woman will be HIV positive and eligible for ARV. Table 3 provides the average weighted cost for a typical or average pregnant woman attending PMTCT services. Table 3. Average cost per pregnant woman attending PMTCT services (US$) Study cost category Average cost % of total cost DIRECT COSTS 70.37 95% Staff 28.45 38% Drugs 13.70 18% Laboratory testing 27.12 37% Medical consumables and supplies 1.10 1% INDIRECT COSTS 3.88 5% Facility Level 2.20 3% Non-client staff time 0.10 0% Office equipment 0.08 0% Physical infrastructure 0.06 0% Transportation costs 0.16 0% Public utilities and running costs 0.16 0% Maintenance and repair 0.76 1% Staff training and volunteers 0.01 0% Local medical and other supply costs 0.84 1% Vehicle costs 0.03 0% General Program Support 1.68 2% Planning and program management 0.03 0% Centrally managed trainings and supervision 1.28 2% Monitoring and evaluation 0.29 0% Communication materials 0.08 0% TOTAL 74.25 100% 5

Estimating the Unit Costs of HIV Prevention of Mother- To-Child Transmission Services in Ghana The same weighting could be applied to the three types of HIV-exposed infants, based on when (or if) the infant sero-converts at six weeks, six months, or 12 months. However, national monitoring systems are not currently able to capture this level of precision. In this case, it is preferable to take a more conservative approach to ensure that adequate resources are available. In this approach, the cost of providing PMTCT services to HIV-exposed infants who are HIV- or HIV+ at 12 months would be estimated. Table 4 provides a simplified example of how to estimate these costs using this approach. PMTCT client type Average pregnant women HIV-exposed infants who are HIV- or HIV+ at 12 months Table 4. Illustrative example of projecting annual costs per client type* Number of clients--example of projections from EPP/Spectrum Unit cost from study (US$) Projected annual cost (US$) 2012 2013 2014 2012 2013 2014 500,000 550,000 600,000 74.25 37,125,000 40,837,500 44,550,000 8,000 8,500 9,000 68.80 550,400 584,800 619,200 TOTAL 37,675,400 41,422,300 45,169,200 *Numbers are not actual program data but are shown here for illustrative purposes only. Projecting annual costs by cost category per average client To obtain specific costs according to different cost categories, the total projected annual costs can be multiplied by the percentage of each cost category as a function of total cost. For example, Table 3 shows that drug costs account for 18 percent of the US$74.25 total cost of providing PMTCT services to an average pregnant woman attending PMTCT services. Thus, if the total projected cost of providing PMTCT services to all average pregnant women attending PMTCT services is estimated at US$37,125,000 for 2012 (as shown in Table 4) and the cost of drugs is 18 percent (as shown in Table 3), the total projected cost for drugs in 2012 is estimated to be: Total Estimated Cost of Drugs in 2012 = US$37,125,000 * 18% = US$6,682,500 For the remainder of this document we will apply the second approach, using the average weighted costs for an average pregnant woman attending PMTCT services and an HIV-exposed infant who is HIV negative or HIV positive at 12 months. 6

Estimating PMTCT costs for the National HIV & AIDS Strategic Plan 2011 15 ESTIMATING PMTCT COSTS FOR THE NATIONAL HIV & AIDS STRATEGIC PLAN 2011 15 Projecting total annual costs per average client When using study results for costing PMTCT for the National HIV & AIDS Strategic Plan (NSP), it is necessary to avoid double costing specific interventions by separating the costs that are specific to the PMTCT program from those that are generally subsumed in the overall cost of running the health sector and are centrally budgeted by the Ghana Health Services (GHS). For example, as shown in Table 1, the cost of direct staff time that medical professionals provide to the PMTCT program is estimated to be 14 percent of the total cost of providing PMTCT services to an HIV-positive pregnant woman on ARV prophylaxis. However, these medical professionals are not all full-time PMTCT staff members; they spread their time across many different clinical services and are budgeted centrally by GHS. To project the cost of the PMTCT program specifically for this component of the NSP, it is necessary to isolate the costs directly attributed to the PMTCT program to avoid double costing. Table 5 presents the distribution of these costs, by cost category used in the study. Table 5. Estimate of PMTCT-specific costs for NSP 2011 15 for average clients attending PMTCT services Study cost category NSP allocation Example of NSP PMTCT-specific cost for an average pregnant woman attending PMTCT services (US$) 7 Example of NSP PMTCT-specific cost for an HIV-exposed infant at 12 months (US$) Cost % Cost % DIRECT COSTS 41.92 94% 50.23 100% Staff General Costs - - - - Drugs PMTCT 13.70 31% 7.57 15% Laboratory testing PMTCT 27.12 61% 41.97 84% Medical consumables and supplies PMTCT 1.10 2% 0.69 1% INDIRECT COSTS 2.59 6% - - Facility Level 0.91 2% - - Non-client staff time General Costs - - - - Office equipment General Costs - - - - Physical infrastructure PMTCT 0.06 0% - - Transportation costs General Costs - - - - Public utilities and running costs General Costs - - - - Maintenance and repair General Costs - - - - Staff training and volunteers PMTCT 0.01 0% - - Local medical and other supply costs PMTCT 0.84 2% - - Vehicle costs General Costs - - - - General Program Support 1.68 4% - -

Estimating the Unit Costs of HIV Prevention of Mother- To-Child Transmission Services in Ghana Planning and program management Centrally managed trainings and supervision PMTCT 0.03 0% - - PMTCT 1.28 3% - - Monitoring and evaluation PMTCT 0.29 1% - - Communication materials PMTCT 0.08 0% - - TOTAL ESTIMATED COST 44.51 100% 50.23 100% Based on the total estimated costs shown in Table 5, program planners can use the estimate of US$44.51 per average pregnant woman attending PMTCT services and US$50.23 for each HIV-exposed infant who is HIV negative or HIV positive at 12 months to represent the average cost of providing PMTCT services. Table 6 provides an illustrative example of how these costs can be applied to the projected number of clients to obtain national cost projections for the NSP to avoid double-costing some services. PMTCT client type Table 6. Illustrative example of projecting annual costs per client type Example of projections from EPP/Spectrum Unit cost from study (US$) Projected annual cost (US$) 2012 2013 2014 2012 2013 2014 Average pregnant women 500,000 550,000 600,000 44.51 22,255,000 24,480,500 26,706,000 HIV-exposed infants who are HIV- or HIV+ 8,000 8,500 9,000 50.23 401,840 426,955 452,070 at 12 months TOTAL 22,656,840 24,907,455 27,158,070 Projecting annual costs by cost category per average client To obtain specific costs per cost category for NSP costing, the total projected annual costs can be multiplied by the percentage of each cost category as a function of total cost. For example, in Table 5 we see that drug costs account for 31 percent of the total cost of providing PMTCT services to an average pregnant woman. Thus, if the total projected cost of providing PMTCT services to all average pregnant women attending PMTCT services is estimated at US$22,255,000 for 2012, as shown in Table 6, the total projected cost for drugs in 2012 is estimated to be: Total Estimated Cost of Drugs in 2012 = US$22,255,000 * 31% = US$6,899,050 8

PMTCT Scale-Up Plan PMTCT SCALE-UP PLAN Projecting total annual costs per average client Because the costing done for the Ghana PMTCT Scale-Up Plan 2011 15 used a slightly different methodology from the joint study, the approach is slightly different. The Scale-Up Plan estimated indirect costs separately at the central level, not as estimates per client as the joint study did. Thus, when using study results for updating the PMTCT Scale-Up Plan 2011 15, it is necessary to use only the direct costs associated with Strategy 6 of the PMTCT Scale-Up Plan: Improve the procurement and supply-chain management system for PMTCT services. The human resource costs that are generally subsumed in the overall cost of running the health sector, which are centrally budgeted by the GHS, are not included in the PMTCT Scale-Up Plan 2011 15. To avoid double costing, it is necessary to consider only the direct commodity costs: drugs, laboratory testing, and medical consumables and supplies. Table 7 presents the distribution of these costs by cost category used in the study. Table 7. Estimate of PMTCT-specific costs for PMTCT Scale-Up Plan 2011 15 for average clients attending PMTCT services Study cost category PMTCT Scale- Up Plan allocation Example of PMTCT Scale-Up Plan cost for an average pregnant woman attending PMTCT services (US$) Example of PMTCT Scale-Up Plan cost for an HIV-exposed infant at 12 months (US$) Cost % Cost % DIRECT COSTS 41.92 100% 50.23 100% Staff General costs - - - - Drugs Strategy 6 13.70 31% 7.57 15% Laboratory testing Strategy 6 27.12 61% 41.97 84% Medical consumables and supplies Strategy 6 1.10 2% 0.69 1% For direct costs, program planners can use the estimate of US$41.92 per average pregnant woman attending PMTCT and US$50.23 for each HIV-exposed infant who is HIV negative or HIV positive at 12 months. Table 8 provides an illustrative example of how these costs and projections can be applied to update the costing in the PMTCT Scale-Up Plan 2011 15 to avoid double-costing some services. Table 8. Illustrative example of projecting annual costs per client type PMTCT client type Average pregnant women HIV-exposed infants who are HIV- or HIV+ at 12 months Example of projections from EPP/Spectrum Unit cost from study (US$) Projected annual cost (US$) 2012 2013 2014 2012 2013 2014 500,000 550,000 600,000 41.92 20,960,000 23,056,000 25,152,000 8,000 8,500 9,000 50.23 401,840 426,955 452,070 9

Estimating the Unit Costs of HIV Prevention of Mother- To-Child Transmission Services in Ghana TOTAL 21,361,840 23,482,955 25,604,070 Projecting annual costs by cost category per average client To obtain specific costs per cost category for updating the PMTCT Scale-Up Plan, the total projected annual costs can be multiplied by the percentage of each cost category as a function of total cost. For example, Table 7 shows that drug costs account for 31 percent of the total cost of providing PMTCT services to an average pregnant woman attending PMTCT services. Thus, if the total projected cost of providing PMTCT services to an average pregnant woman attending PMTCT services is estimated at US$20,960,000 for 2012, as shown in Table 8, the total projected cost for drugs in 2012 is estimated to be: Total Estimated Cost of Drugs in 2012 = US$20,960,000 * 31% = US$6,497,600 USING STUDY RESULTS FOR RESOURCE MOBILIZATION AND ALLOCATION: GLOBAL FUND APPLICATIONS AND PEPFAR COUNTRY OPERATIONAL PLANS Projecting total annual costs per average client When using study results for costing PMTCT contributions to Global Fund applications or for PEPFAR Country Operational Plans (COPs), it is necessary to avoid double costing by separating the costs that are specific to the PMTCT program from the costs that are subsumed in the overall cost of running the health sector, which are centrally budgeted by the GHS. Table 9 presents the distribution of these costs by cost category used in the study. Table 9. Estimate of PMTCT-specific costs for GF and PEPFAR planning for average clients attending PMTCT services Study cost category Global Fund cost categories Donor allocation to PMTCT Example of PMTCTspecific cost for an average pregnant woman attending PMTCT services (US$) Example of PMTCT-specific cost for an HIVexposed infant at 12 months (US$) Cost % Cost % DIRECT COSTS - - 41.92 94% 50.23 100% Staff Human resources General costs - 0% - - Drugs Medicine and pharmaceutical products PMTCT 13.70 31% 7.57 15% Procurement and Laboratory testing supply management PMTCT 27.12 61% 41.97 84% Medical consumables and supplies Health products and equipment PMTCT 1.10 2% 0.69 1% INDIRECT COSTS - - 2.50 6% - - Facility Level - - 0.85 2% - - Non-client staff time Human resources General costs - 0% - - 10

Using Study Results for Resource Mobilization and Allocation: Global Fund applications and PEPFAR Country Operational Plans Office equipment Physical infrastructure Transportation costs Public utilities and running costs Maintenance and repair Infrastructure and other equipment Infrastructure and other equipment Procurement and supply management Planning and administration Planning and administration General costs General costs General costs General costs General costs Staff training and volunteers Training PMTCT Local medical and other supply costs Vehicle costs Health products and equipment Infrastructure and other equipment PMTCT General Costs 11-0% - - - 0% - - - 0% - - - 0% - - - 0% - - 0.01 0% - - 0.84 2% - - - 0% - - General Program Support - - 1.65 4% - - Planning and program management Planning and administration General Costs Centrally managed trainings and supervision Training PMTCT Monitoring and evaluation M&E PMTCT Communication materials Communication PMTCT - 0% - - 1.28 3% - - 0.29 1% - - 0.08 0% - - TOTAL ESTIMATED COST - - 44.42 100% 50.23 100% Program planners can use the estimate of US$44.42 per average pregnant woman attending PMTCT and US$50.23 for each HIV-exposed infant who is HIV negative or HIV positive at 12 months. Table 10 provides an illustrative example of how these costs and projections can be applied to obtain national cost projections to be used for costing the NSP to avoid double-costing some services. PMTCT Client Type Table 10. Illustrative example of projecting annual costs per client type Example of projections from EPP/Spectrum Unit cost from study (US$) Projected annual cost (US$) 2012 2013 2014 2012 2013 2014 Average pregnant 500,000 550,000 600,000 44.42 women 22,210,000 24,431,000 26,652,000 HIV-exposed infants who are HIV- or HIV+ 8,000 8,500 9,000 50.23 401,840 426,955 452,070 at 12 months TOTAL 22,611,840 24,857,955 27,104,070 Projecting annual costs per cost category per average client To obtain specific costs per cost category for costing PMTCT-specific contributions from Global Fund or PEPFAR to the national PMTCT program, the total projected annual costs can be multiplied by the percentage of each cost category as a function of total cost. For example, Table 9 shows that drug costs account for 31 percent of the total cost of providing PMTCT services to an average pregnant woman attending PMTCT services.

Estimating the Unit Costs of HIV Prevention of Mother- To-Child Transmission Services in Ghana Thus, if the total projected cost of providing PMTCT services to all average pregnant women attending PMTCT services is estimated at US$22,210,000 for 2012, as shown in Table 10, the total projected cost for drugs in 2012 is estimated to be: Total Estimated Cost of Drugs in 2012 = US$22,210,000 * 31% = US$6,885,100 In summary, the estimates from the joint study are based on the costs per client type. These estimates can be applied to projections of the number of women and infants in future years to estimate an annual cost per client and per cost category. Because the GHS includes some costs for providing PMTCT services as part of its central budget, program planners need to estimate the remaining PMTCT costs and include them in the NSP, the PMTCT Scale-Up Plan, Global Fund applications, and PEPFAR COPs. This guide provides examples of the various calculations needed for these applications. 12

REFERENCES UNAIDS. 2011. Spectrum/Epidemic Projection Package, v. 4.50. Retrieved on April 12, 2013, from http://www.unaids.org/en/dataanalysis/datatools/spectrumepp2011/. 13

For more information, contact: Health Policy Project Futures Group One Thomas Circle, NW, Suite 200 Washington, DC 20005 Tel: (202) 775-9680 Fax: (202) 775-9694 Email: policyinfo@futuresgroup.com http://www.healthpolicyproject.com