safety margin, To leave a functioning i larynx i.e. respiration, phonation & swallowing.

Similar documents
Organ preservation in laryngeal cancer

Compartmentalization of the larynx Sites and subsites Supraglottis Glottis subglottis Spaces Pre-epiglottic epiglottic space Para-glottic space

Laser Cordectomy. Glottic Carcinoma

AJCC Cancer Staging 8 th edition. Lip and Oral Cavity Oropharynx (p16 -) and Hypopharynx Larynx

Treatment for Supraglottic Ca History: : Total Laryngectomy y was routine until early 50 s, when XRT was developed Ogura and Som developed the one-sta

Surf, Sea and Supracricoid Laryngectomy: A Queensland Experience. Jeeve Kanagalingam Associate Consultant Tan Tock Seng Hospital Singapore

A220: Larynx cancer tissues. (formalin fixed)

Please refer back to the slides as these are extra notes only. Slide 2 -The Larynx is a Box of cartilage.

Surgery in Head and neck cancers.principles. Dr Diptendra K Sarkar MS,DNB,FRCS Consultant surgeon,ipgmer

Evaluation and Treatment of Dysphagia in the Head and Neck Cancer Patient

NAACCR Webinar Series 11/2/2017

Carcinoma of the larynx L 4. Carcinoma of the larynx is the most common head & neck cancer, this has a high cure rate which may reach 90%.

Use of Larynx-Preservation Strategies in the Treatment of Laryngeal Cancer. American Society of Clinical Oncology Clinical Practice Guideline

Anatomy of the Airway

12 Larynx. I - Cartilages. Learning Objectives

Case Scenario 1. Pathology: Specimen type: Incisional biopsy of the glottis Histology: Moderately differentiated squamous cell carcinoma

T1/T2 LARYNX CANCER. Click to edit Master Presentation Date. Thomas J Gernon, MD Otolaryngology-Head and Neck Surgery

Anatomy of Head of Neck Cancer

NAACCR Hospital Registry Webinar Series

MANAGEMENT OF CA HYPOPHARYNX

OPEN ACCESS ATLAS OF OTOLARYNGOLOGY, HEAD & NECK OPERATIVE SURGERY

Alexander C Vlantis. Total Laryngectomy 57

MULTIDISCIPLINARY MGMT. OF INTERMEDIATE STAGE LARYNGEAL CANCER, ROBERT L. FERRIS, MD 1

Anatomo-surgical correlations in larynx cancer

Larynx. Rudimentary. Behind the posterior surface : -stylopharyngeus - salpingopharyngeus -platopharyngeus

The Larynx. Prof. Dr.Mohammed Hisham Al-Muhtaseb

Structure and Nerve Supply of The Larynx

Case Scenario #1 Larynx

Hypopharynx and larynx anatomy

Original Article Analysis of surgical methods and their long-term effect on laryngeal carcinoma

Learning objectives Describe anatomically and clinically the di ifference between laryngeal cancer and hypopharyngeal cancer Be able to describe clini

JOSE FRANCISCO GALLEGOS HERNANDEZ Hospital de Oncología, CMN SXXI. IMSS México City.

RADIO- AND RADIOCHEMOTHERAPY OF HEAD AND NECK TUMORS. Zoltán Takácsi-Nagy PhD Department of Radiotherapy National Institute of Oncology, Budapest 1.

Contents. Part A Clinical Evaluation of Laryngeal Disorders. 3 Videostroboscopy and Dynamic Voice Evaluation with Flexible Laryngoscopy...

Wojciech K. Mydlarz, M.D. Pharyngocutaneous Fistulas after Salvage Laryngectomy: Need for Vascularized Tissue

Assessing The Survival And Functional Outcomes Of Patients With Supraglottic Squamous Cell Carcinoma

FACULTY OF MEDICINE SIRIRAJ HOSPITAL

Survey of Laryngeal Cancer at SBUH comparing 108 cases seen here from to the NCDB of 9,256 cases diagnosed nationwide in 2000

Head & Neck Clinical Sub Group. Network Agreed Imaging Guidelines for UAT and Thyroid Cancer. Measure Nos: 11-1C-105i & 11-1C-106i

LARYNX ANATOMY. Elena Rizzo Riera R1 ORL HUSE

External trauma (MVA, surf board, assault, etc.) Internal trauma (Endotracheal intubation, tracheostomy) Other

1/14/2019 CRITICAL PATHWAYS IN HEAD AND NECK CANCER DISCLOSURES OBJECTIVES

Esophagus Stomach 4/2/15

2. Guidelines for Reporting Head and Neck Tumours

AJCC Staging of Head & Neck Cancer (7 th edition, 2010) -LIP & ORAL CAVITY-

Principles of Management of Head & Neck Cancer. Jinka Sathya Associate professor of Oncology

Respiratory System. Clinical notes. Published on Second Faculty of Medicine, Charles University (

The International Federation of Head and Neck Oncologic Societies. Current Concepts in Head and Neck Surgery and Oncology

Supracricoid partial laryngectomy (SCPL) was first

L ARYNX S TAGING F ORM

C. Douglas Phillips, MD FACR Director of Head and Neck Imaging Weill Cornell Medical Center NewYork Presbyterian Hospital

Dr. Sami Zaqout Faculty of Medicine IUG

Ultrasound Interpretation of Non-Thyroid Neck Pathology

Early management of laryngeal injuries'

Mohammed AlEssa MBBS,FRCSC Consultant Otolaryngology,Head & Neck Surgery King Saud University- medical city National guard health affairs KAMC

Airway Anatomy. Soft palate. Hard palate. Nasopharynx. Tongue. Oropharynx. Hypopharynx. Thyroid cartilage

Larynx - cartilaginous structure holding the vocal folds which protrude into airstream

Prevertebral Region, Pharynx and Soft Palate

Case Scenario. 7/13/12 Anterior floor of mouth biopsy: Infiltrating squamous cell carcinoma, not completely excised.

Laryngeal schwannoma - A rarely occurring benign tumor.

Dr J K Jekel Dept. Surgery University of Pretoria

The following images were all acquired using a CTI Biograph

Case Scenario 1. 7/13/12 Anterior floor of mouth biopsy: Infiltrating squamous cell carcinoma, not completely excised.

Thyroid INTRODUCTION ANATOMY SUMMARY OF CHANGES

NURSE-UP RESPIRATORY SYSTEM

Laryngeal Preservation Using Radiation Therapy. Chemotherapy and Organ Preservation

Hyoid Bone. Lower Airway. Aspiration. Larynx. Cartilages of the Larynx. Larynx Tracheobronchial Tree (TB Tree) Trachea Bronchi Bronchioles

Laryngeal Conservation

Adenoid Cystic Carcinoma Minor Salivary Gland Origin

Self-Assessment Module 2016 Annual Refresher Course

VOCAL CORD PALSY. Department of ENT, Head and Neck Surgery DR OSEGHALE DR AKPALABA

Case Presentation. Faysal Ghazzay Ahmed

Tympanic Bulla Temporal Bone. Digastric Muscle. Masseter Muscle

SmartXide 2 - SmartXide HS

THE RESPIRATORY SYSTEM

Organ-Preservation Strategies in head and neck cancer. Teresa Bonfill Abella Oncologia Mèdica Parc Taulí Sabadell. Hospital Universitari

Information and support

Neck Dissection. Asst Professor Jeeve Kanagalingam MA (Cambridge), BM BCh (Oxford), MRCS (Eng), DLO, DOHNS, FRCS ORL-HNS (Eng), FAMS (ORL)

Head and Neck Pathology. Macroscopy and Dissection Dr Tim Bracey Consultant Pathologist (Derriford Hospital)

Transoral Laser Microsurgery in Carcinomas of the Oral Cavity, Pharynx, and Larynx

Preservation of laryngeal function improves outcomes of patients with hypopharyngeal carcinoma

Department of Otolaryngology, Kurume University School of Medicine, Kurume, Japan

The Oncologic Safety and Functional Preservation of Supraglottic Partial Laryngectomy

CT in Carcinoma of the Larynx and Pyriform Sinus:

Hypopharyngeal Carcinoma: A Review

Modified frontolateral partial laryngectomy operation: combined muscle-pedicle hyoid bone and thyrohyoid membrane flap in laryngeal reconstruction

Pediatric Endoscopic Airway Management With Posterior Cricoid Rib Grafting

AIRWAY MANAGEMENT SUZANNE BROWN, CRNA

Respiratory System Structures and Gas Exchange

The management of advanced supraglottic and

Unilateral Supraglottoplasty for Severe Laryngomalacia in Children. Nasser A Fageeh, MD, FRCSC, FACS*

Case Presentation JC: 65 y/o retired plumber CC: Hoarseness HPI: Admitted to a local hospital on May 30 for severe pneumonia. Intubated in ICU for 10

Head and Neck Tumours

Hoarseness. Common referral Hoarseness reflects any abnormality of normal phonation

Clinical Discussion. Dr Pankaj Chaturvedi. Professor and Surgeon Tata Memorial Hospital

LARYNGEAL CANCER AT THE KORLE BU TEACHING HOSPITAL ACCRA GHANA

After reviewing this module, the student will have the ability to: - Create a broad differential diagnosis for the hoarse patient

Larynx (Nonepithelial tumors such as those of lymphoid tissue, soft tissue, bone, and cartilage are not included)

Upper Respiratory Tract

Case Scenario 1. Pathology report Specimen from mediastinoscopy Final Diagnosis : Metastatic small cell carcinoma with residual lymphatic tissue

Transcription:

The aim of the horizontal supra-glottic laryngectomy is: To remove the tumour with good safety margin, To leave a functioning i larynx i.e. respiration, phonation & swallowing.

Disadvantages of classical surgery Tracheostomy may be permanent Long hospital stay Aspiration due to : Superior laryngeal nerve injury Injury of suprahyoid musculature Aspiration may necessitate total laryngectomy in up to 10% of cases ( Suaraz et al 1996 ). Dissected Tissues in classical surgery Epiglottis. Pre-epiglotticepiglottic space. Ary-epiglottic folds. False vocal cords. Superior half of the thyroid cartilage.

The same achievement could be done by LASER Epiglottis. Pre-epiglotticepiglottic space. Ary-epiglottic folds. False vocal cords.?? Superior half of the thyroid cartilage. When we do supraglottic laser surgery T staging of supraglottic carcinoma T1 - Tumor limited to one subsite T2 - Tumor extended from one site to other site or region with mobile cords T3 - Tumor extended d to - vocal cord with fixed mobility of the cords - mucosa of the post cricoid region - pre-epiglottic space T4 - Tumor extended out side the thyroid cartilage

Limitation of laser surgery Extension of the tumor: Out side the thyroid cartilage. To the hyoid bone or to the thyrohyoid y ligament. Incompatible larynx after surgery i.e. If both arytenoids are involved. If both vocal cords are involved. Exposure difficulties e.g. high larynx, short neck or large tongue. Technique of laser surgery

Technique of laser surgery Technique of laser surgery

75 years female, epiglottic ca. extended to Rt. ventricular band and Rt. aryepiglottic fold Operative technique Second postoperative p day One week later 6 years later

Pre-operative One year post op khattab fekery one year post op.wmv khattab fekery pre op.wmv

48year male, supraglottic malignancy destroying the epiglottis and extended to tongue base and both aryepiglottic folds Pre-operative 9 month Post op ramadan mohamed 5 years after op.mpg 5 years Post-op Advantages of laser surgery No bleeding and Minimal edema. No external wound Border between healthy and tumor tissue can be easily identified Tumor imbolization through lymphatic vessels is blocked by laser coagulation of the lymph vessels. Mostly no tracheotomy. Constant view of the two dimensional extension of the tumor mass. Sphincteric function is preserved Minimal post operative hospital stay, most of the patients can leave the hospital in the same day of the operation.

Thank you Radiotherapy after laser, why? There is no guarantee about the tumor margin due to: The wide field of tumor bed. Micro vascular emboli. To cover undetected neck lymph nodes. The local control rate T stage radiotherapy Laser Radiotherapy + Laser T1 71-80% 82-90% 90-95% T2 56-64 % 59-74 % 64-84% T3 56-64 % 74-80%

Lymph node problem The situation here is different from the open neck surgery. Strategy for lymph node management LN stage Tstage N0 N1/2 N3 + + + T1/4 T1/4 T1/4 Management No interference Functional neck surgery Radical neck surgery

48 patients, 44 males and 4 females (age range 40-80) had been managed by : Supraglottic laryngectomy followed by curative dose of radiotherapy, Neck dissection was done for N+ve cases only. Conclusion The oncological results of combined LASER and Rdith Radiotherapy in the control of the supra-glottic carcinoma are satisfying and definitely improve the out come of the disease

Thank you Prof. Wageeze backgrounds series T stage No. patients t N0 N1 N2 T1 10 9 1 - T2 18 14 3 1 T3 15 12 1 2 T4 5 1 2 2

Number of cases Surgical procedure 36 Laser supraglottic laryngectomy Laser supraglottic laryngectomy 7 + unilateral F N D 5 Laser supraglottic laryngectomy + Bilateral F N D Local and regional control rate Locall control: For T1 lesions 100% while for laser alone 82-95% and for radiotherapy alone 71-80% For T2 lesions 94% while for laser only 64-84% and for radiotherapy 59-74% For T3 lesions 86% while for laser only 56-64% Lymph node control: N0 100% N1 85% N2 60%

T stage No of Local N No of cases recurrence stage cases L N recurrence T1 10 0 N0 36 0 T2 18 1 N1 7 1 T3 15 2 N2 5 2 T4 5 2 Anatomically Supraglottic larynx is different from the glottic & the subglottic region: Embryology Pressman(1956) dye injection Pathologically Supraglottic carcinoma tend to respect the genetic of their territory It often show exophytic feature and may fill the whole hl vestibule bt but stop at the level of the vocal cords

Understanding the anatomy & the tumor extension, form the bases of the horizontal supra-glottic laryngectomy.