Complex Airway problems - Paediatric Perspective

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Complex Airway problems - Paediatric Perspective Dave Albert BACO Liverpool 2009 www.albert.uk.com

Complex Ξ not simple, multiple parts Multiple problems with airway Combined Web/stenosis/multiple levels Multiple problems with child Syndromic children Difficult to treat Poor outcomes Posterior laryngeal stenosis Multiple previous surgery

Complex laryngeal stenosis congenital Severe congenital web/stenosis Complete tracheal rings High take off right upper lobe bronchus

Complex laryngeal stenosis syndromic Larsen s syndrome Epidermolysis bullosa Velo cardio facial syndrome

Complex laryngeal stenosis previous surgery Very scarred larynx from multiple laser Stenosis following laser for papillomatosis Posterior scar bands with cricoarytenoid fixation

What do we treat? Paeds vs adult UPPER AIRWAY Laryngomalacia Subglottic haemangiomas, webs and clefts Difficult decannulation Vocal Cord movement disorders Subglottic stenosis Complex stenosis Tumours LOWER AIRWAY Tracheomalacia- intrinsic Extrinsic compression Tracheal stenosis Tumours

What do we both treat? UPPER AIRWAY Laryngomalacia Subglottic haemangiomas, webs and clefts Difficult decannulation Vocal Cord movement disorders Subglottic stenosis Complex stenosis Tumours LOWER AIRWAY Tracheomalacia- intrinsic Extrinsic compression Tracheal stenosis Tumours

Paediatric Subglottis

More difficult when very small!

Techniques UPPER AIRWAY Cartilage grafting Resection Dilatation/stents Lateralisation LOWER AIRWAY Tracheoplasty Dilatation/stents Laryngeal transplant Pacing Tissue engineering

Current paediatric techniques Endoscopic Open FESS style surgery Sharp rather than Laser Radial Dilatation Lateralisation Microdebrider Endoscopic Stents/keels T-Tubes Cricoid split Cartilage grafts single/2 stage Cricotracheal resection

History 60 s Premature infants survive Acquired Subglottic Stenosis Tracheostomy 70 s Open laryngeal surgery, Rib graft repair 80 s Cricoid split to deal with early cases 90 s Single stage laryngeal reconstruction Partial cricotracheal resection 2000+ Endoscopic techniques

Number of Patients 35 30 LTP LTR CTR 25 20 15 10 5 0 1972 1974 1976 1978 1980 1982 1984 1986 1988 1990 1992 1994 1996 1998 2000 2002 2004 Year

Paediatric Subglottic stenosis Management Medical Endoscopic Open procedures

Paediatric tube management Smallest stable tube Oral or nasal Shouldered or straight Steroids (pre extubation) Anti-reflux treatment Optimal status pre extubation Laryngeal rest Duration not main factor

Endoscopic Treatment Sharp removal subglottic cysts granulations Division of thin webs Gentle radial dilatation Mitomycin C Endoscopic cricoid split (all with stenting and steroids)

Sharp avulsion of cysts

Endoscopic cricoid split

Cut edges of cricoid

Radial dilatation and Mitomycin C Angioplasty balloon up to 16 Atmospheres! Antineoplastic antibiotic - acts as an alkylating agent by inhibiting DNA and protein synthesis

Endoscopic web division

Failed extubation with stridor Paediatric Tube management Medical management Optimise extubation MLB Endoscopic Rx SGS Granulations, cysts, edema Soft SGS Cricoid split Mature SGS Re-intubate Single stage LTR Success

Open procedures Anterior Cricoid split- split and stent procedure for neonates with failed extubation due to early SGS Laryngotracheal Reconstruction (LTR) framework expansion with cartilage grafts for mature stenosis Cricotracheal resection resection with end on end anastomosis for total or near total stenosis

Decompression Cricoid Split

Cricoid Split Indications Soft edema > 1.5 kg Fit Procedure Split-1 ring, cricoid and ½ thyroid Postoperative care Intubated for 5-7 days. Not paralysed or ventilated Antibiotics Exubate under steroid cover Re-intubated-check length Drain

Single stage LTR Augmentation procedure that aims to combine all elements into one operation. Period of intubation instead of stent

Laryngofissure in intubated patient

Rib graft harvest

Graft placement

SSLTR - Postoperative care Intubated for 7 days. Not paralysed or ventilated Antibiotics Exubate under steroid cover Dexamethasone 0.25mg/kg then 0.1mg/kg QDS Reintubate with care if needed **

Conventional LTR with tracheostomy Traditional Staged procedure using a stent

LTR Augmentation Rib cartilage Anterior Posterior

LTR with stent - Indications Severe stenosis grade III-IV Complicating medical conditions Child/parent not keen on ITU Still need to optimise medical conditions especially reflux

Expose strap muscles

Expose larynx

Laryngofissure

Posterior split

Stent

Anterior graft

Endoscopic posterior graft

Endoscopic posterior graft

Results of LTR Cotton 1989 Decannulation rate Patient Procedures (%) Grade 2 97% 95 129 (33%) Grade 3 91% 80 94 (17%) Grade 4 72% 25 28 (12%)

Results of LTR - GOSH 266 procedures (presented ESPO Helsinki Evans 1998) Grade 2 94% Grade 3 90% Grade 4 66%

Partial Cricotracheal resection Grade III-IV Usually as a single stage Upper excision below cords preserve posterior cricoid cricoid plate drilled to reduce stenosis

Cricotracheal resection

Cricotracheal resection Intubate for 7-10 days Scope prior to extubation and downsize No longer use lateral tension sutures or neck sutures

Cricotracheal resection

Partial Cricotracheal Resection Monnier 1993

Cricotracheal resection

My current guidelines Grade I Conservative II Endoscopic if soft LTR once established III LTR CTR if severe and clear of cords IV LTR CTR if clear of cords

Complete Tracheal Cartilage Rings

Slide Tracheoplasty

Balloon dilatation of metal stents

The Future Paediatric and adult laryngology will continue to learn techniques from each other Laryngeal transplantation, laryngeal pacing and tissue engineering are very exciting developments

BAPO Meeting 2009 Lowry Hotel Manchester September 18 th www.bapo.org.uk