Please note the following changes to the Immunization Program:

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1 August 22, 2003 ATTN: Medical Health Officers and Branch Offices Public Health Nursing Administrators and Assistant Administrators Holders of Communicable Disease Control Manuals Re: Revisions to the Immunization Program Please note the following changes to the Immunization Program: (1) Section II Immunization Schedules Page 7, Vaccines recommended for high risk clients: meningococcal conjugate and meningococcal polysaccharide vaccines are recommended for recipients of solid organ transplants. Pages 8,10,11, and 12, Immunization Schedules: for clarity, names of the biological products containing diphtheria/pertussis/tetanus have been written in full, rather than only abbreviated. Page 11, Schedule C: timing for third dose of TdaP is twelve months after the second visit. Page 13, Schedule E: clarification regarding eligibility of adults for polio booster. Administrative Circular: 2003:11

2 (2) Section VII Biological Products Page 5, Haemophilus B Conjugate Vaccine (Act-HIB ): the second indication for this vaccine now specifies "unimmunized" persons older than 5 years of age with the listed conditions. the third indication for the vaccine separates out recipients of hematopoietic stem cell transplants (HSCT) as this group requires 3 doses of Hib Page 7, Hepatitis A Vaccine (Havrix ): Page 8, Hepatitis A Vaccine (Vaqta ): In the footnotes: addition of Avaxim Pediatric as another interchangeable hepatitis A Page 9, Hepatitis A Vaccine (Avaxim ): Page 9a, Hepatitis A Vaccine (Avaxim Pediatric): new page, product licensed for age 12 months to 15 of years inclusive. Page 10, Hepatitis A Vaccine (Epaxal Berna ):

3 Page 12, Hepatitis B Immune Globulin (Bayhep B ): the ventrogluteal site can be used for those > 7 months of age. However, Page 18, Hepatitis B Vaccine (RecombivaxHB ): Page 24, Hepatitis A and B Vaccine Combined (Twinrix ): Page 25, Hepatitis A and B Vaccine Combined (Twinrix Junior ): Page 27, Immune Globulin (Baygam ): the ventrogluteal site can be used for those >7 months of age. However, Page 34, Measles/Mumps/Rubella Vaccine (Priorix ): addition of anaphylactic reaction to latex as a contraindication to Priorix vaccine (pre-filled syringe of diluent).

4 Page 37, Meningococcal C Conjugate Vaccine (Neis Vac-C): addition of grade 6 students as a group eligible for this Pages 39 and 40, Meningococcal Polysaccharide Vaccine (Menomune ): Page 41, Pneumococcal Conjugate Vaccine (Prevnar ): revised footnote regarding completion of immunization when the primary series has been interrupted. Page 41a, Completion of primary series when conjugate pneumococcal vaccination has been interrupted (healthy or high risk children): this is a new page that specifies the scheduling of conjugate pneumococcal vaccination when the primary series has been interrupted. Page 42, Recommendations for Pneumococcal Immunization With 7-Valent Pneumococcal Conjugate Vaccine (PCV 7) and 23-Valent Pneumococcal Polysaccharide Vaccine (PPV 23) for Children at High Risk of Pneumococcal Disease: revisions made to be consistent with page 41a. addition of anaphylactic reaction to latex as a contraindication for Prevnar and Pneumo 23. Page 43, Pneumococcal Polysaccharide Vaccine (Pneumo 23 ): Page 44, Polio Vaccine: clarification regarding booster dose for travelers to endemic areas.

5 Page 45, Human Rabies Immune Globulin (HRIG) (Imogam ): information pertaining to site of administration has been made consistent with recommendations in the Rabies Control Guidelines. The ventrogluteal site can be used for those > 7 months of age. However, the vastus lateralis is most often used for infants and children up to 5 Page 46, Human Rabies Immune Globulin (HRIG) (Imogam ): Pages 47 and 50, Rabies Vaccine (Imovax Rabies): addition of anaphylactic reaction to latex as a contraindication/precaution to this Page 52, Tetanus-Diphtheria (Td) Adsorbed: vaccine (multidose vial presentation). Page 53, Tetanus-Diphtheria-acellular Pertussis Vaccine(TdaP): the word individuals replaces children for clarification re: vaccine eligibility. Page 55, Tetanus Immune Globulin (TIG) Baytet : the ventrogluteal site can be used for those >7 months of age. However, Page 59, Typhoid Vaccine (Typhim Vi ):

6 Page 61, Typhoid Vaccine (Typherix ): Page 62, Varicella Zoster Immune Globulin (VZIG): the ventrogluteal site can be used for those >7 months of age. However, Please remove and destroy the following pages from the Immunization Chapter of the Communicable Disease Control Manual: Section II Pages 7, 8, 10, 11, 12 & 13 Dated June 2003 Section VII Table of Contents Dated June 2003 Pages 5, 12, 25, 43, 45, 46, 52, 55, 59, 61, & 62 Dated March 2003 Pages 24, 37, 39, 40, 41, 42 & 53 Dated June 2003 Pages 7, 8, 9, 10, 18, 27, 34, 44, 47, & 50 Dated November 2002 Insert the following pages in the Immunization Chapter: Section II Pages 7, 8, 10, 11,12 & 13 Dated August 2003 Section VII Table of Contents Dated August 2003 Pages 5, 7, 8, 9, 9a, 10, 12, 18, 24, 25, 27, 34, 37, 39, 40, 41, 41a, 42, 43, 44, 45, 46, 47, 50, 52, 53, 55, 59, 61, &62 Dated August 2003

7 These revisions to the Immunization Chapter of the Communicable Disease Control Manual are posted on the BCCDC website at: If you have any questions or concerns, please contact Karen Pielak, Nurse Epidemiologist, or Cheryl McIntyre, Associate Nurse Epidemiologist, at telephone (604) 660-6061, fax (604) 660-0197 or e-mail karen.pielak@bccdc.ca or cheryl.mcintyre@bccdc.ca. Sincerely, David Patrick Director Epidemiology Services BC Centre for Disease Control DMP/kka pc: Dr Perry Kendall Dr. Shaun Peck Provincial Health Officer Deputy Provincial Health Officer Ministry of Health Services Ministry of Health Services Dr. Bob Fisk Medical Consultant Non-Communicable Disease Services Ministry of Health Planning Lorna Storbakken Director Disease and Injury Prevention Branch Ministry of Health Planning Jane Crickmore Public Health Nursing Consultant Disease and Injury Prevention Branch Ministry of Health Planning