Falls prevention strategies for people with visual impairment

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Falls prevention strategies for people with visual impairment Clare Robertson University of Otago Medical School Dunedin, New Zealand

Vision loss in Australia 480,000 visually impaired in both eyes (visual acuity <6/12); 50,000 are blind (<6/60) Age related macular degeneration (AMD) is leading cause of irreversible blindness Cataract (2.7M in 2021) Diabetic eye disease Glaucoma (1 person in 11) Under corrected refractive error (300,000) Eye Research Australia 2004

Vision loss in Australia Eye Research Australia 2004

Risk factors for falls Mean RR/OR (95%CI) Mean Muscle weakness 4.4 (1.5 10.3) History of falls 3.0 (1.7 7.0) Balance deficit 2.9 (1.6 5.4) Visual deficit 2.5 (1.6 3.5) Psychotropic drugs 1.7 (1.5 2.0) Age >80 years 1.7 (1.1 2.5) Panel on Falls Prevention. J Am Geriatr Soc 2001;49:664-72 Leipzig RM et al. J Am Geriatr Soc 1999;47:30-50

Visual function and falls Visual acuity Contrast sensitivity Visual fields Depth perception Black A & Wood J. Clin Exp Optom 2005;88:212-22

Prevention Vision interventions Modifiable risk factors (eg smoking cessation, antioxidants, avoid UV exposure) Detection Regular eye examinations ( >less decline in vision, function) Treatment Cataracts, glaucoma management, AMD, free glasses/magnifier ( >vision specific QoL ) Black A & Wood J. Clin Exp Optom 2005;88:212-22

Multifocal glasses and falls N=156 men & women aged 63 to 90 years 56% regularly wore multifocal (bifocal, trifocal, progressive) glasses Multifocal versus non-multifocal glasses fallers at 1 year: OR 2.29, 95% CI 1.06 4.92 Distant depth perception & distant edge-contrast sensitivity tests worse for multifocal wearers Lord SR et al. J Am Geriatr Soc 2002;50:1760-6

1. Vision improvement N=1,090 men & women aged 70 years Brochure; referral to eye care provider, GP, optometrist 5% new glasses (N=20) or surgery (N=6) First fall after 18 months: Hazard ratio 0.89, 95% CI 0.75 1.04, p=0.13 Effective when combined with group exercise programme Day L et al. BMJ 2002;325:128

2. First eye cataract surgery N=306 women 70 years Expedited (4 weeks) versus routine (12 months) cataract removal Number of fallers at 1 year: 49% operated vs 45% non-operated fell, NS Rate of falls at 1 year: IRR 0.66, 95% CI 0.45 0.96, p=0.03 Harwood RH et al. Br J Ophthalmol 2005;89:53-9

3. Second eye cataract surgery N=239 women 70 years Expedited (4 weeks) versus routine (12 months) cataract removal Number of fallers at 1 year: 40% operated vs 34% non-operated fell, NS Rate of falls at 1 year: IRR 0.68, 95% CI 0.39 1.19, p=0.18 Foss AJE et al. Age Ageing 2006;35:66-71

4. Vision assessment & treatment N=616 men & women 70 years Comprehensive vision & eye examination new glasses (30%) referred to OT (8%) glaucoma management (6%) cataract surgery (5%) Cumming RG et al. J Am Geriatr Soc (in press)

4. Vision assessment & treatment Number of fallers at 1 year: 65% intervention vs 50% control fell, p=0.002 Rate of falls at 1 year: IRR 1.57, 95% CI 1.20 2.05, p=0.001 More fractures in intervention group 31 vs 18, p=0.06 Hot off the press! Cumming RG et al. J Am Geriatr Soc (in press)

4. Vision assessment & treatment Differential quality of reporting of falls in the 2 groups? Controls more frail at baseline (less time walking about/more cautious) Controls visited eye professional? Major changes in prescriptions for new glasses Only 1 person new bi- or multifocals Improving vision/reassurance > behaviour change? Cumming RG et al. J Am Geriatr Soc (in press)

5. Visually Impaired Persons (VIP) fall prevention trial Funding: NZ Health Research Council Campbell AJ et al. BMJ 2005;331:817-20

VIP falls prevention trial Physiotherapists delivered the Otago Exercise Programme for 1 year Occupational therapists delivered a home safety programme and facilitated modifications. Assessment adapted from Westmead (glare, lighting, contrast)

Strength and balance retraining http://www.acc.co.nz/otagoexerciseprogramme

Previous evidence Otago Exercise Programme 4 controlled trials 2 research setting, 2 routine healthcare services N = 1,016 women and men, 65 to 97 years Meta-analysis showed falls 35%, injurious falls 35% Effective when delivered by a physiotherapist, and trained nurses Most cost effective: 80 years + previous fall Robertson MC et al. J Am Geriatr Soc 2002;50:905-11

Otago Exercise Programme adapted for low vision

Previous evidence Home safety intervention Recruited on hospital discharge OT assessment, advice, facilitation Falls 25%, 31% in previous fallers Cost saving in previous fallers Cumming RG et al. J Am Geriatr Soc 1999;47:1397-402 Nikolaus T et al. J Am Geriatr Soc 2003;51:300-5

Home safety programme

VIP falls prevention trial Randomised controlled trial 2 by 2 factorial design Recruited from Royal NZ Foundation of the Blind and low vision clinics in Dunedin and Auckland, New Zealand Visual acuity 6/24 or worse, 75 years 88% with AMD (self reported)

VIP falls prevention trial Women and men 75 years; vision 6/24 n = 708 Randomisation n = 391 Home safety + Exercise programme Home safety Exercise programme n = 98 n = 100 n = 97 n = 96 Social visits

Fall calendars 001 Participants filled in F for a fall or N for no fall each day Prospective, daily recall for 1 year Monthly follow up Independent monitor Circumstances & consequences by telephone Independent assessor

Eye tests in the home

VIP results Otago Exercise Programme Exercise No exercise (n=195) (n=196) No. of falls 228 215 Falls per person year 1.23 1.13 No. of injurious falls 114 104 IRR 1.15, 95% CI 0.82 1.61, p=0.418 Campbell AJ et al. BMJ 2005;331:817-20

VIP results Otago Exercise Programme Frequency IRR (95% CI) < 1 session per week 1.00 1 < 2 0.79 (0.42 1.50) 2 < 3 0.37 (0.23 0.60) 3 0.23 (0.12 0.45) Campbell AJ et al. BMJ 2005;331:817-20

VIP results Home safety programme compliance Telephone interview by OT at 6 months 152 of 169 (90%) complied at least partially with 1 home safety recommendation(s) Campbell AJ et al. BMJ 2005;331:817-20

VIP results Home safety programme Home safety (n=198) No home safety (n=193) No. of falls 172 271 Falls per person year 0.91 1.47 No. of injurious falls 100 118 IRR 0.59, 95% CI 0.42 0.83, p=0.002 Campbell AJ et al. BMJ 2005;331:817-20

Campbell AJ et al. BMJ 2005;331:817-20

Hazard related falls Home safety programme > falls 41% At home Away from home Hazard related falls at home IRR 0.40, 95% CI 0.21 0.74 Non-hazard related falls at home IRR 0.43, 95% CI 0.21 0.90 La Grow SJ et al. Injury Prevention 2006;12:296-301

How did it work? In addition to removal or modification of hazards / new equipment: Individual advice given by OT? Overall reduction in activity? Combination of reasons that vary with each individual? La Grow SJ et al. Injury Prevention 2006;12:296-301

Visual impairment & falls - a challenge!

Key messages - vision loss People with vision loss are at double the risk of falls (hip # ) Vision specific interventions Wear monofocal glasses while walking New glasses could cause falls First cataract removal reduces falls Home safety assessment & modification (experienced OT) reduces falls

Key messages - general Effective strategies in those with normal sight do not necessarily work in people with severe vision loss Two components not necessarily better than one single intervention Value for money requires careful targeting (general population versus specific risk factor)