INTERNATIONAL
Martindale Pharma is a UK pharmaceutical manufacturing company supplying niche products to over 50 countries worldwide. Our vision Making Lives Better drives every action and decision of the company. This applies to everyone involved with our company, from our employees to our distributors, our customers in local hospitals and government agencies, and most importantly, the patients using our medicines. With a history tracing back to the 18th century, we continue to be a leading UK supplier of injectables, oral solutions, suppositories and ophthalmic drops and ointments. Our History 1787: James Macarthy founded a retail pharmacy in Romford, later to become Macarthy Ltd 1873: William Martindale bought a pharmacy in central London 1933: W. Martindale was acquired by Savory & Moore Ltd 1967: Savory & Moore Ltd was acquired by Macarthy Ltd 1990: Martindale Pharmaceuticals launched as a trading style for Macarthys Laboratories Ltd 1991: Martindale Pharmaceuticals move to purpose built facility in Harold Hill, within a few kilometres of where James Macarthy founded his original pharmacy 1992: Macarthy plc acquired by Lloyds Chemists plc 1994: Martindale acquires Daniels Pharmaceuticals and enters the ophthalmics market 1995: Further acquisitions lead to the launch of the Martindale Specials business 1999: Aurum acquired and Martindale enters the Pre Filled Syringe sector 2000: Brentwood facility commissioned 2003: Acquired by Cardinal Health 2009: Methadone launched into multiple markets 2010: AAC Capital acquires Martindale from Cardinal Health 2014: Martindale relocates headquarters to High Wycombe in Buckinghamshire. Martindale Pharma has a comprehensive network of local and international specialist distributors, with particular strength in the Middle East, Australia, Africa, selected markets in Europe, Asia and the Caribbean. Customer service is crucial to our success and hearing a familiar voice on the phone or a swift reply to an email from your Martindale Pharma contact are integral to our approach to serving our customers. Our international team has the experience and depth of knowledge to manage the shipment of our goods, including Controlled Drugs (Narcotics), to our export customers across the globe.
Martindale Pharma supplies critical care injections to hospital in over 30 countries across five continents
Pain Relief/CNS Drugs To many international customers, the name Martindale Pharma is synonymous with Controlled Drugs (CDs) or Narcotics. In several countries, the supply of opioid analgesics has been central to the growth of the business partnership. Whilst the mix of products from an ever increasing portfolio may have broadened, the detailed adherence and understanding of the import and export processes for Controlled Drugs (CDs) across international borders remains a cornerstone to the Martindale Pharma export business. In the WHO three-step analgesic ladder, opioids are divided into those used for mild to moderate pain, including Codeine and Dihydrocodeine and those for moderate to severe pain, including Morphine, Pethidine and Fentanyl. The ones from the first group are distinguished by the existence of a ceiling effect and are often used with non opioid analgesics. Repeated administration of these drugs may cause dependence and tolerance and treatment should always be supervised by a specialist and the patient assessed at regular intervals. The Martindale Pharma range includes CDs in a number of dosage forms, which dependent on sufficient volume can be manufactured to country specific strengths and supplied in local packaging. INTERNATIONAL JOB NUMBER: MART/02/ 2017/022 DATE OF PREPARATION: FEB 2017 01 / 06
Pain Relief/CNS Drugs Fentanyl 01 Morphine 02 50mcg/ml in 2ml 50mcg/ml in 10mg/ml in 1ml 15mg/ml in 1ml 20mg/ml in 1ml 30mg/ml in 1ml Pethidine 03 Phenobarbital 04 50mg/ml in 1ml 50mg/ml in 2ml 30mg/ml in 1ml 60mg/ml in 1ml 200mg/ml in 1ml Building A2, Glory Park Glory Park Avenue, Wooburn Green High Wycombe. HP10 0DF United Kingdom t +44 (0) 1628 551900 f +44 (0) 1628 529848 e connect@martindalepharma.co.uk w martindalepharma.co.uk
Addiction Martindale Pharma is one of the leading UK suppliers of Methadone for the treatment of Opioid Drug addiction. Our Methadone is currently registered in Ireland, Malta, Kenya and South Africa, with further registration applications submitted in Europe and the Middle East. With over 15 years experience in manufacturing Methadone to a precise and consistent formulation, all our products are manufactured under GMP conditions. Formulations include Alcohol free, Sugar free, Lycosine free and orange flavoured variants. In 2013 Martindale Pharma increased its portfolio for the treatment of Opioid Drug Addiction and launched the first presentation of Naloxone to be licensed for emergency use in the home or other nonmedical setting. In 2017, Martindale Pharma added Espranor to the group of Addiction products. Espranor oral lyophilisate is a freeze-dried wafer, which dissolves rapidly on the tongue. This represents another first-in-class development, and demonstrates the commitment of Martindale Pharma to this therapy area. INTERNATIONAL JOB NUMBER: MART/02/ 2017/022 DATE OF PREPARATION: FEB 2017 02 / 06
Addiction Methadone 01 The presentations available are: Oral solutions Injections Tablets Latest formulation: Martindale Pharma has developed a 2mg/ml methadone formulation with the following benefits. Sugar free Alcohol free Lycosine free Orange flavor 3 year shelf-life Prenoxad (Naloxone Hydrochloride) 02 Prenoxad Injection (naloxone hydrochloride 1mg/1ml solution for injection) contains 2 ml naloxone hydrochloride 1 mg/ml. Espranor 03 Espranor 2 mg oral lyophilise. Each oral lyophilisate contains 2 mg of buprenorphine (as hydrochloride). Each oral lyophilisate contains 0.50 mg aspartame. Espranor 8 mg oral lyophilise. Each oral lyophilisate contains 8 mg of buprenorphine (as hydrochloride). Each oral lyophilisate contains 2.00 mg aspartame. Building A2, Glory Park Glory Park Avenue, Wooburn Green High Wycombe. HP10 0DF United Kingdom t +44 (0) 1628 551900 f +44 (0) 1628 529848 e connect@martindalepharma.co.uk w martindalepharma.co.uk
Hospital Specialty Specialist Parenteral Injections supplied in oules or vials remain core to Martindale Pharma s business. In addition to the Narcotics detailed in the previous section, the range of niche injectables available support the treatment of many medical conditions and surgical procedures. As well as products from its in house manufacturing capability, Martindale Pharma has entered into partnerships with a number of other specialist cgmp manufacturers, offering an enhanced spectrum of products and presentations, for exle, 50 ml vials and aseptically filled oules. INTERNATIONAL JOB NUMBER: MART/02/ 2017/022 DATE OF PREPARATION: FEB 2017 03 / 06
Hospital Specialty Acetylcysteine 01 Ephedrine 02 200mg/ml in 30mg/ml in 1ml 30m/ml in 30mg/ml in PFS Adrenaline 03 Glycopyrronium Bromide 04 1 in 1,000 in 1ml 1 in 1,000 in 0.5ml 1 in 1,000 in 5ml 1 in 10,000 in 1 in 10,000 in 1ml 1 in 10,000 in 5ml 1 in 1,000 in 1ml Anaphylaxis PFS 1 in 1,000 in 1 ml Paediatric PFS 1 in 10,000 in PFS 0.2mg/ml in 1ml 0.2mg/ml in 3ml Glycopyrronium Bromide 0.5mg/ml and Neostigmine Metilsulfate 2.5mg/ml Cardioplegia 05 Magnesium Sulphate 06 Infusion Concentrate 20ml 1g in 2ml (50%) 5g in 10m (50%) 2.5g in 5ml (50%) 10% in Building A2, Glory Park Glory Park Avenue, Wooburn Green High Wycombe. HP10 0DF United Kingdom t +44 (0) 1628 551900 f +44 (0) 1628 529848 e connect@martindalepharma.co.uk w martindalepharma.co.uk
Oral Suspensions Martindale Pharma has a strong background in the Unlicensed or Specials business. Specials are medicinal products prescribed, administered and supervised by doctors for a specific indication, either when a licensed product does not exist or is not currently available on the market. Martindale Pharma has licensed some of its oral suspensions, making these molecules the first licensed oral liquid suspensions in the UK. INTERNATIONAL JOB NUMBER: MART/02/ 2017/022 DATE OF PREPARATION: FEB 2017 04 / 06
Oral Suspensions Tapclob (Clobazam) 01 Noyada (Captopril) 02 5mg/5ml in 150ml bottle 10mg/5ml in 150ml bottle 5mg/5ml in 100ml bottle 25mg/5ml in 100ml bottle Martapan (Dexamethasone) 03 Dexamfetamine 04 2mg/5ml in 150ml bottle 1mg/ml in 500ml bottle Building A2, Glory Park Glory Park Avenue, Wooburn Green High Wycombe. HP10 0DF United Kingdom t +44 (0) 1628 551900 f +44 (0) 1628 529848 e connect@martindalepharma.co.uk w martindalepharma.co.uk
Retail Specialty and Critical Care Martindale Pharma continues to invest in additional products to compliment and strengthen the range for both the UK and our international markets. Obstetrics Caffeine Citrate Caffeine Citrate 10mg/ml. Each 1ml of solution contains, 10mg Caffeine citrate, equivalent to 5mg of Caffeine. Sodium Citrate 01 02 Sodium Citrate 0.3M Oral Solution. 2.647g of Sodium Citrate in 30ml of Oral Solution INTERNATIONAL JOB NUMBER: MART/02/ 2017/022 DATE OF PREPARATION: FEB 2017 05 / 06
Retail Specialty and Critical Care Pre-filled s PRTC (Plastic Rigid Tip Cap) Emergency Range 03 Ophthalmology Our range of products cover the leading ophthalmic diseases: Glaucoma, Conjunctivitis and Dry eye. 04 Our PFS are latex-free, Luer Lock compatible and designed to reduce tip breakage. Adrenaline Atropine Ephedrine Amiodarone Naloxone Calcium Chloride (intravenous infusion) Chlorhenicol Timolol Vista Methasone Hypromellose Pilocarpine Atropine Latanoprost Dorzolamide / Timolol Carmellose Ear, Nose and Throat 05 Suppositories 06 Lidocaine Hydrochloride 5% & Phenylephrine Hydrochloride 0.5% BIPP (Bismuth subnitrate and iodoform paste) Morphine Paracetamol Aspirin Building A2, Glory Park Glory Park Avenue, Wooburn Green High Wycombe. HP10 0DF United Kingdom t +44 (0) 1628 551900 f +44 (0) 1628 529848 e connect@martindalepharma.co.uk w martindalepharma.co.uk
Therapeutic groups & alphabetical list of products Therapeutic class Code Product Strength Presentation Pack Size ACE inhibitor 14300 Noyada (Captopril) 5mg/5ml Oral Solution 100ml ACE inhibitor 14301 Noyada (Captopril) 25mg/5ml Oral Solution 100ml Alkalinizer 17039 Sodium Bicarbonate BP 8.4%w/v Anaesthetic 17010 Cardioplegia Infusion Concentrate Anaesthetic 77108 Cocaine Hydrochloride Anaesthetic 77113 Lidocaine Hydrochloride 5% & Phenylephrine 0.5% 20ml 10% nasal spray 2.5ml nasal spray Analgesic 78100 Aspirin 150mg suppository Analgesic 78101 Aspirin 300mg suppository Analgesic 78105 Paracetamol 120mg suppository Analgesic 78106 Paracetamol 240mg suppository Analgesic 78107 Paracetamol 500mg suppository Analgesic 78119 Paracetamol 1000mg suppository Analgesic/Antidote for methanol poisoning Analgesic/Antidote for methanol poisoning 170820 Ethanol BP (Dehydrated Alcohol) 17804 Ethanol BP (Dehydrated Alcohol) Antiarrhythmic agent 66332 Amiodarone 300mg in 2.5ml 100% 2ml 100% 5ml Antibiotic 74452 Chlorhenicol BP 1%w/w eye ointment Antibiotic 34400 Chlorhenicol BP 10%w/v ear drop Antibiotic 34401 Chlorhenicol BP 5%w/v ear drop Antibiotic 74447 Chlorhenicol BP 0.5%w/v eye drop Anticholinergic 17092 Glycopyrronium Bromide Anticholinergic 17091 Glycopyrronium Bromide Anticholinergic 17052 Hyoscine Hydrobromide BP Anticholinergic 17055 Hyoscine Hydrobromide BP Anticholinesterases 17093 Glycopyrronium Bromide and Neostigmine Metilsulfate Antidote for Paracetamol overdose Antidote in methaemoglobinemia 4g 0.2mg/ml 1ml 0.2mg/ml 3ml 400mcg/ ml 600mcg/ ml 0.5mg/ml 2.5mg/ml 1ml 1ml 1ml 77142 Acetylcysteine 200mg/ml 77066 Methylthioninium Chloride PROVEBLUE 5mg/ml Antimuscarinic agent 66304 Atropine Sulfate 1mg in 5ml Antimuscarinic agent 66305 Atropine Sulfate 3mg in Antimuscarinic agent 66330 Atropine Sulfate 600mcg/ ml 5ml Antimuscarinic agent 74461 Atropine Sulfate BP 1%w/v eye drop Antimuscarinic agent 17004 Atropine Sulfate BP 400mcg/ ml Antimuscarinic agent 17005 Atropine Sulfate BP 600mcg/ ml Antimuscarinic agent 17008 Atropine Sulfate BP 1mg/ml 1ml Antiseptic 73100 BIPP pouch 30g Antiseptic 73101 BIPP 1.25 x 100cm gauze Antiseptic 73102 BIPP 1.25 x 200cm gauze 1ml 1ml 1ml Therapeutic class Code Product Strength Presentation Pack Size Antiseptic 73103 BIPP 1.25 x 300cm gauze Antiseptic 73104 BIPP 2.5 x 100cm gauze Antiseptic 73105 BIPP 2.5 x 200cm gauze Antiseptic 73106 BIPP 2.5 x 300cm gauze Barbiturate 17026 Phenobarbitone Sodium BP Barbiturate 17027 Phenobarbitone Sodium BP Barbiturate 17028 Phenobarbitone Sodium BP Benzodiazepine 77118 Midazolam 50mg in 50ml Benzodiazepine 77134 Midazolam 100mg in 50ml Benzodiazepine 14891/ 75405 Benzodiazepine 14892/ 75416 Tapclob Oral Suspension (Clobazam) Tapclob Oral Suspension (Clobazam) CNS Stimulant 14890 Dexamfetamine Sulfate 200mg/ml 1ml 30mg/ml 1ml 60mg/ml 1ml 5mg/5ml 10mg/5ml vial vial Oral Suspension Oral Suspension 50ml 50ml 150ml 150ml 1mg/ml Oral Solution 500ml Corticosteroid 74400 Vista Methasone TM eye drop Corticosteroid 74401 Vista Methasone TM eye drop 5ml replacement replacement replacement replacement replacement/ anticonvulsant replacement/ anticonvulsant replacement/ anticonvulsant replacement/ anticonvulsant replacement/ anticonvulsant 17009 Calcium Chloride 10mmol 17018 Calcium Chloride 5mmol 5ml 66307 Calcium Chloride Intravenous Infusion 17031 Potassium Acid Phosphate 100mg in 1ml (10%) 77114 Magnesium Sulfate 1g in 2ml (50%) 77115 Magnesium Sulfate 5g in (50%) 17056 Magnesium Sulfate 4g in 20ml (20%) 77128 Magnesium Sulfate 2.5g in 5ml (50%) 10mmol 2ml 20ml 5ml 17021 Magnesium Sulfate 10%w/v Glucocorticoid 14097 Dexamethasone Sodium Phosphate (Martapan) 2mg/5ml solution 150ml K+ supplement 170035 Potassium Chloride 20%w/v Laxative / Lubricant 78108 Glycerol BP Adult suppository 4g Laxative / Lubricant 78109 Glycerol BP Children's suppository 2g Laxative / Lubricant 78110 Glycerol BP Infant suppository 1g Lubricant 74454 Carmellose (Melophthal) Lubricant 74453 Carmellose (Melophthal) 0.5% UDV eye drop 0.4ml 1% UDV eye drop 0.4ml Lubricant 74446 Hypromellose BPC 0.3%w/v eye drop Lubricant 74454 Melophthal (Carmellose) Lubricant 74453 Melophthal (Carmellose) 0.5% UDV eye drop 0.4ml 1% UDV eye drop 0.4ml Please note: Not all products are licensed or available in all countries. INTERNATIONAL JOB NUMBER: MART/02/ 2017/022 DATE OF PREPARATION: FEB 2017 06 / 06
Therapeutic class Code Product Strength Presentation Pack Size Lubricant 74409 Simple BP eye ointment Miotic 74426 Pilocarpine BP 1%w/v eye drop Miotic 74427 Pilocarpine BP 2%w/v eye drop Miotic 74429 Pilocarpine BP 4%w/v eye drop Non-selective betablocker Non-selective betablocker Neuromuscular blocking agent 74437/ 74468 74438/ 74469 Timolol 0.25%w/v eye drop 5ml Timolol 0.5%w/v eye drop 5ml 17087 Suxamethonium Chloride 4g 50mg/ml 2ml Opioid analgesic 17805 Codeine Phosphate BP 60mg/ml 1ml Opioid analgesic 19804 DF118 TM forte 40mg tablet Opioid analgesic 79100 Diamorphine 10mg tablet Opioid analgesic 14814 Dihydrocodeine Elixir 10mg/5ml liquid 150ml Opioid analgesic 17836 Dihydrocodeine Injection BP Opioid analgesic 17067 Fentanyl Citrate 100mcg/ 2ml Opioid analgesic 17068 Fentanyl Citrate 500mcg/ Opioid analgesic 14823 Morphine Oral Solution Opioid analgesic 14824 Morphine Oral Solution Opioid analgesic 14825 Morphine Oral Solution 50mg/ml 1ml 10mg in 5ml 10mg in 5ml 10mg in 5ml Opioid analgesic 77119 Morphine Sulfate 50mg in 50ml Opioid analgesic 77120 Morphine Sulfate 100mg in 50ml liquid liquid liquid Opioid analgesic 78102 Morphine Sulfate 10mg suppository Opioid analgesic 17807 Morphine Sulfate BP 10mg/ml 1ml Opioid analgesic 17808 Morphine Sulfate BP 15mg/ml 1ml Opioid analgesic 17809 Morphine Sulfate BP 30mg/ml 1ml Opioid analgesic 17815 Morphine Sulfate BP 20mg/ml 1ml Opioid analgesic 19803 Pethidine BP 50mg tablet Opioid analgesic 77812/ 17812 Opioid analgesic 77813/ 17813 vial vial 2ml 100ml 300ml 500ml 50ml 50ml Pethidine BP 50mg/ml 2ml Pethidine BP 50mg/ml 1ml Opioid analgesic 17814 Pethidine BP 10mg/ml 5ml Opioid analgesic / Addiction Opioid analgesic / Addiction Opioid analgesic / Addiction Opioid analgesic / Addiction 14010 Methadone Oral Solution DTF 14012 Methadone Oral Solution DTF 14005 Methadone Oral Solution Sugar Free 14007 Methadone Oral Solution Sugar Free Opioid antagonist 66323 Naloxone Hydrochloride Opioid antagonist 66336 Prenoxad 1mg/ml injection (Naloxone Hydrochloride) 1mg/ml liquid 500ml 1mg/ml liquid 2.5ltr 1mg/ml liquid 500ml 1mg/ml liquid 2.5ltr 2mg in 2ml 1mg/ml 2ml 2ml Therapeutic class Code Product Strength Presentation Pack Size Opioid partial agonist-antagonist Opioid partial agonist-antagonist 19812 Espranor 2mg wafer 19813 Espranor 8mg wafer Oral care 54019 Dentural - Denture Cleanser Parenteral Parenteral Prostaglandin analogue Respiratory Analeptic Respiratory Analeptic liquid 250ml 77129 Sodium Chloride 30% w/v vial 50ml 17043 Sodium Chloride BP 30%w/v 74450 Latanoprost 0.005% eye drop 2.5ml 17185 Caffeine Citrate Solution for Injection 17285 Caffeine Citrate Oral Solution 10mg/ml 1ml 10mg/ml bottle 5ml Stimulant laxative 78115 Bisacodyl BP 10mg suppository amine amine amine Treatment of glaucoma Treatment of glaucoma 66311 Ephedrine Hydrochloride 17015 Ephedrine Hydrochloride 17014 Ephedrine Hydrochloride 66300 Adrenaline (Epinephrine) 77127 Adrenaline (Epinephrine) 66321 Adrenaline (Epinephrine) Anaphylaxis 66302 Adrenaline (Epinephrine) Paediatric 30mg in 30mg in 30mg/ml 1ml 1mg in (1:10,000) 1mg in (1:10,000) 1mg in 1ml (1:1,000) 1mg in 1ml (1:1,000) 1ml 1ml 17080 Adrenaline BP 1:10,000 1ml 17081 Adrenaline BP 1:10,000 5ml 17082/ 17301 27984/ 17305 Adrenaline BP 1:10,000 Adrenaline BP 1:1000 5ml 17001 Adrenaline BP 1:1000 0.5ml 17002/ 17300 Adrenaline BP 1:1000 1ml 74466 Dorzolamide/Timolol 20mg/ml + 5mg/ml 74465 Latanoprost/Timolol 50mcg/ml + 5mg/ml eye drop eye drop 5ml 2.5ml Urinary Alkaliniser 75421 Sodium Citrate 0.3M liquid 30ml Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Martindale Pharma. Tel: +44 1277 266600. Fax: +44 1708 382739. Email: drugsafety@martindalepharma.co.uk Please note: Not all products are licensed or available in all countries. Building A2, Glory Park Glory Park Avenue, Wooburn Green High Wycombe. HP10 0DF United Kingdom t +44 (0) 1628 551900 f +44 (0) 1628 529848 e connect@martindalepharma.co.uk w martindalepharma.co.uk
Building A2, Glory Park Glory Park Avenue Wooburn Green High Wycombe HP10 0DF United Kingdom t +44 (0) 1628 551900 f +44 (0) 1628 529848 e connect@martindalepharma.co.uk w martindalepharma.co.uk Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Martindale Pharma Tel: +44 1277 266600. Fax: +44 1708 382739. Email: drugsafety@martindalepharma.co.uk MART/02/ 2017/022 DATE OF PREPARATION: FEB 2017