Food Integrity Reference standards for testing food quality, safety and authenticity

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reference standards matrix materials certified reference materials proficiency testing reference standards matrix materials Food Integrity Reference standards for testing food quality, safety and authenticity LGC Quality ISO Guide 34 GMP/GLP ISO 9001 ISO/IEC 17025 ISO/IEC 17043

Consumer confidence in food relies on the effectiveness of checks to ensure the safety, consistency and authenticity of food products. The focus on the integrity of food has increased globally in recent years and as a consequence, new regulations and higher standards on quality control and testing are either planned or being implemented. Global trade in food and food products also means that exporters must meet international requirements and demonstrate security of the supply chain. The reliability and accuracy of analytical results is essential to ensuring consistent product quality and safety. Accurate monitoring of food is supported by the use of reference materials. Participation in suitable proficiency testing schemes provides independent assurance of the competency of staff and the suitability of equipment, methods and procedures. LGC has over 25 years experience in manufacturing and supplying reference materials for the food and beverage sectors.

Food quality LGC produces world leading ISO Guide 34 accredited certified reference materials (CRMs), matrix reference materials and quality control materials (QCs). Together with our network of leading international partners, we supply reference materials for the analysis of proximates, nutritional elements and vitamins in matrices including: meat, fish and vegetable matter cereals and grains milk and dairy products food and drink products Food nutritional and compositional testing can be undertaken to demonstrate compliance with food labelling requirements and to satisfy food chain requirements such as retailer specifications and as a part of due diligence and surveillance programs. LGC offers an extensive range of reference standards including: food constituents and natural products - sugars, carotenoids, amino acids and vitamins food additives - preservatives, antioxidants, sweeteners and colourings. LGC has played a vital role in assisting authorities in fighting food crime by developing a range of materials used for the detection of adulteration of lamb and beef. Speciation, authenticity and GMO Meat speciation In 2013, the horsemeat scandal exposed the presence of various species in both raw and processed meats sold across Europe. Consequently, meat speciation analysis has become increasingly important in tackling food fraud. Food authenticity Isotopic methods are now in routine use for food authenticity testing, based on the measurement of the stable isotope content (deuterium, 13 C, 18 O, etc.) of food or ingredients. These methods can provide information on the botanical and geographical origin of the food product. Genetically modified organisms (GMOs) The marketing of GMOs and food or feed derived from GMO is controlled in many geographic areas. In the EU, there is a stringent approval procedure used in the authorisation of such products. LGC offers a range of reference materials for use in method validation, calibration and quality control in meat speciation, food authenticity and GMO testing.

Food safety Allergens Detecting and identifying allergens effectively is an important part of surveillance, regulatory and commercial control of cross contamination, and food labelling. Quantification of allergens can be challenging as inconsistent results are sometimes observed when using different biochemical test kits from varying sources. Current methods detect either the allergenic protein (ELISA, mass spectroscopy) or allergenic food type DNA (PCR). To meet the demand for a reliable source of reference for a peanut allergen, LGC have developed and manufactured a quality control material kit for the detection of peanut allergen in food, with a blank material and a matrix material with peanut protein added at 10 ppm (mg kg -1 ). Organic Contaminants Contamination in food and food products can originate from diverse sources. The increasing adoption of LC-MSMS has highlighted that matrix effects can have a detrimental impact on measurement. The use of isotopically labelled compounds as internal standards can negate these effects. LGC offers an extensive range of in-house manufactured organic contaminants standards. The Dr. Ehrenstorfer range includes approximately 8,000 different products, available as individual components (neat and in solution) as well as mixtures. We also offer a range of organic contaminant standards from other manufacturers enabling us to provide a complete range of reference standards to meet your requirements. Pesticides Organochlorines Organophosphates Carbamates Pyrethroids Neonicotinoids Quaternary ammonium pesticides Sulfonylurea pesticides

Veterinary drugs and related compounds Antibiotics, anthelmintics and anticoccidials Sedatives, NSAIDs and corticosteroids Nitrofuran metabolites and beta agonists Steroids and hormones Other EU unauthorised compounds including chloramphenicol, nitromidazoles, stilbenes, thyreostatic drugs and zeranol. Dyes Industrial dyes including sudan I, II, III and IV, rhodamine B, toluidine red and orange II Fungicides including malachite and leucomalachite green, crystal violet and leucocrystal violet Food colours including sunset yellow (E110) and tartrazine (E102). Naturally occurring toxins Some foods (fruits, vegetables and flowers) naturally contain potentially harmful toxins. Fungal mycotoxins can contaminate food directly through contamination of crops, or indirectly through the food chain from contaminated animal feed. A comprehensive range of mycotoxin standards and reference materials is available, including native and isotopically labelled standards, solutions and complex food matrices. LGC looks to its network of international experts such as Laboratorio CIFGA in the area of marine biotoxins. Working together, we offer a broad range of reference standards for cyanotoxins, algal neurotoxins and paralytic shellfish poisons, including domoic acid, okadaic acid, saxitoxin and mycrocystins. Inorganic reference materials Elemental analysis is undertaken in food products as part of nutritional / compositional testing to support labelling claims and for the detection of possible inorganic contaminants such as heavy metals. LGC offers an extensive range of inorganic standards for AA, ICP and IC methodology under the VHG brand, manufactured in our ISO Guide 34 accredited facility in the USA. LGC can satisfy all your laboratory quality needs, including proficiency testing, analytical services and training. Proficiency Testing schemes include: QMAS - Meat and Fish Analysis QDCS - Dairy Chemistry QFCS - Food Chemistry QCS - Chocolate QMS - Food Microbiology AFPS - Animal Feed QGS - Gelatine

For further information, or if you require substances or materials not currently listed please contact one of our local sales offices. Brazil Tel: +55 12 3302 5880 Email: bz@lgcstandards.com Bulgaria Tel: +359 (0)2 971 4955 Email: bg@lgcstandards.com China Tel: 800 810 4630 (toll-free) Email: infochina@lgcgroup.com France Tel: +33 (0)3 88 04 82 82 Email: fr@lgcstandards.com Germany Hungary India Tel: +91 (0)80 6701 2000 Email: in@lgcpromochem.com Ireland Tel: +44 7879556983 Email: ire@lgcstandards.com Italy Tel: +39 02 2412 6830 Email: it@lgcstandards.com Middle East Netherlands Tel: +31 (0)643 775 422 Email: nl@lgcstandards.com Nordic countries Poland Tel: +48 22 751 31 40 Email: pl@lgcstandards.com Romania Tel: +40 364 116890 Email: ro@lgcstandards.com Russia Tel: +7 812 777 04 88 Email: ru@lgcgroup.com South Africa Tel: +27 (0)11 466 4321 Email: info@industrialanalytical.co.za Spain Tel: +34 (0)93 308 4181 Email: es@lgcstandards.com Turkey Tel: +90 216 360 0870 Email: tur@lgcstandards.com United Kingdom Tel: +44 (0)20 8943 8480 Email: uksales@lgcstandards.com USA + Canada Tel: 1-855-LGC-USA1 (toll-free) Email: lgcusa@lgcstandards.com www.lgcstandards.com Science for a safer world Brazil Bulgaria China Czech Republic France Germany Hungary India Ireland Italy Netherlands Nordic countries Poland Romania Russia South Africa Spain Turkey United Kingdom USA All trademarks and registered trademarks mentioned herein are the property of their respective owners. All other trademarks and registered trademarks are the property of LGC and its subsidiaries. Specifications, terms and pricing are subject to change. Not all products are available in all countries. Please consult your local sales representative for details. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording or any retrieval system, without the written permission of the copyright holder. LGC Limited, 2014. All rights reserved. 4221/LB/0115