Inhaled bronchodilators relax constricted airways and treat the noisy part of asthma: coughing, wheezing, choking and shortness of breath. AccuNeb inhalation 0.021% solution: 0.63mg/3mL 3-4 times solution 0.042% solution: 1.25 mg/3ml Advair Diskus 100/50 250/50 500/50 Advair HFA 45/21 115/21 230/21 Alent inhalation 100mcg /50mcg 250mcg /50mcg 500mcg /50mcg 45mcg /21mcg 115mcg /21mcg 230mcg /21mcg 0.021% solution: 0.63mg/3mL 0.042% solution: 1.25 mg/3ml 0.083% solution: 2.5mg/3mL. 5% solution: 2.5mg/0.5mL metaproterenol sulfate 3-4 times 65 mcg per inhalation 3-4 times 2 yrs & Dey L.P. 4 yrs & 2 yrs & 2 yrs & 2 yrs & GlaxoSmithKline Note: Advair does not replace fast-acting s for sudden symptoms and should not be taken more than twice a day. Advair HFA now has an integrated dose counter various manufacturers DISCONTINUED Charts Updated August 18, 2010 Copyright 2010 All Rights Reserved Page 1
Inhaled bronchodilators (continued) Atrovent HFA inhalation Brovana Combivent Dulera DuoNeb inhalation solution Foradil! Aerolizer ipratropium bromide HFA ar tartrate ipratroprium bromide and mometasone furoate and ipratroprium bromide and 21 mcg per inhalation 4 times 2 ml/2.1ml 18 mcg ipratropium bromide/ 103 mcg per inhalation 100 mcg mometasone/5 mcg 200 mcg mometasone/5 mcg 0.5mg ipratropium/3mg albuterol in 3mL unit dose vials 4 times 4-6 times 12 mcg per inhalation Note: Atrovent is not indicated for the initial treatment of acute episodes of bronchospasm where rapid response is required. Sepracor Note: Brovana is not indicated to relieve acute respiratory symptoms Merck Inc. Dey 5 yrs & Schering Corp. Note: Foradil is not indicated to relieve acute asthma symptoms. Charts Updated August 18, 2010 Copyright 2010 All Rights Reserved Page 2
Inhaled Bronchodilators (continued) ipratroprium bromide ipratropium bromide and Maxair" Autohaler metaproterenol sulfate Perforomist ipratroprium bromide ipratropium bromide and pirbuterol acetate metaproterenol sulfate breath-actuated ProAir HFA HFA Proventil! HFA Serevent! Diskus! xinafoate 0.02% solution: 0.5mg/2.5mL 0.5mg ipratropium/3mg albuterol in 3mL unit-dose vials 3-4 times 4-6 times 200 mcg per inhalation 3-4 times 0.4% solution: 10mg/2.5mL 0.6% solution: 15mg/2.5mL 3-4 times 20mcg/2mL 90 mcg per inhalation 3-4 times 108 mcg per inhalation 3-4 times 50 mcg per inhalation various various manufacturers 3M Pharmaceuticals various manufacturers Dey Note: Perforomist is not indicated to treat asthma or acute deteriorations of COPD 4 yrs & TEVA Respiratory 4 yrs & Schering Corp. 4 yrs & GlaxoSmithKline Note: Serevent should not be used to relieve acute asthma symptoms Charts Updated August 18, 2010 Copyright 2010 All Rights Reserved Page 3
Inhaled bronchodilators (continued) Spiriva HandiHaler Symbicort inhalation 80/4.5 160/4.5 tiotropium bromide budesonide and Ventolin HFA Xopenex inhalation solution Xopenex inhalation solution concentrate Xopenex HFA levalbuterol HCI levalbuterol tartrate 18 mcg per inhalation 1 time per day 80mcg budesonide/4.5mcg per inhalation 160mcg budesonide/4.5mcg per inhalation 108 mcg per inhalation 3-4 times 0.31mg/3mL unit-dose vial 0.63mg/3mL unit-dose vial 1.25mg/3mL 1.25mg/0.5mL 3 times 45 mcg per inhalation 3-4 times 12 yrs and Note: Spiriva is not indicated for the initial treatment of acute episodes of bronchospasm. AstraZeneca Note: Symbicort is not indicated for the relief of acute bronchospasm. manufacturers Symbicort (HFA) now has an integrated dose counter 4 yrs & GlaxoSmithKline Note: Ventolin HFA now has an integrated dose counter 6 yrs & 4 yrs & Sepracor Inc. Charts Updated August 18, 2010 Copyright 2010 All Rights Reserved Page 4
Inhaled corticosteroids and other anti-inflammatory medications reduce and prevent airway inflammation (swelling). Used daily, anti-inflammatories treat the underlying part of asthma patients may not feel. Advair Diskus 100/50 250/50 500/50 Advair HFA 45/21 115/21 230/21 AeroBid AeroBid -M (menthol) flunisolide Aerospan HFA flunisolide Alvesco HFA 80 mcg 160 mcg Asmanex Twisthaler 110 mcg 220 mcg Azmacort inhalation ciclesonide mometasone furoate triamcinolone acetonide 100mcg /50mcg 250mcg /50mcg 500mcg /50mcg 45mcg /21mcg 115mcg /21mcg 230mcg /21mcg 250 mcg per inhalation 80 mcg per inhalation 80 mcg per inhalation 160 mcg per inhalation 1-110 mcg per inhalation 220 mcg per inhalation 100 mcg per inhalation 2-4 times 4 yrs & Charts Updated August 18, 2010 Copyright 2010 All Rights Reserved Page 5 GlaxoSmithKline Note: Advair does not replace fast-acting s for sudden symptoms and should not be taken more than twice a day. Advair HFA now has an integrated dose counter 6 yrs & Forest Pharmaceuticals Inc. 6 yrs & Acton Pharmaceuticals NOT YET AVAILABLE Sepracor Inc. 4 yrs & Schering Corp. 6 yrs & Kos Pharmaceuticals DISCONTINUED
Inhaled corticosteroids and other anti-inflammatories (continued) cromolyn sodium Dulera Flovent Diskus 50 mcg 100 mcg 250 mcg Flovent HFA 44 mcg 110 mcg 220 mcg Intal Inhaler cromolyn sodium mometasone furoate and formoerol propionate cromolyn sodium 10mg/mL 4 times 100 mcg mometasone/5 mcg 200 mcg mometasone/5 mcg 50 mcg per inhalation 100 mcg per inhalation 250 mcg per inhalation 44 mcg per inhalation 110 mcg per inhalation 220 mcg per inhalation 800 mcg per inhalation 4 times Pulmicort Respules budesonide 0.25mg/2mL unit-dose ampule 0.5mg/2mL unit-dose ampule 1mg/2mL unit-dose ampule Pulmicort Flexhaler 90 mcg per inhalation 90 mcg 180 mcg per inhalation 180 mcg QVAR 40 mcg 80 mcg Symbicort inhalation 80/4.5 160/4.5 beclomethasone dipropionate HFA budesonide and 40 mcg per inhalation 80 mcg per inhalation 80mcg budesonide/4.5mcg per inhalation 160mcg budesonide/4.5mcg per inhalation 1- a day 2 yrs & various manufacturers Merck Inc. Note: Dulera has an integrated dose counter 4 yrs & GlaxoSmithKline Note: Flovent HFA now has an integrated dose counter 5 & King Pharmaceuticals DISCONTINUED 12 months 8 yrs 6 yrs & AstraZeneca LP 5 yrs & Teva Specialty Pharmaceuticals LLC AstraZeneca Note: Symbicort is not indicated for the relief of acute bronchospasm. Charts Updated August 18, 2010 Copyright 2010 All Rights Reserved Page 6
Leukotriene Modifiers Accolate zafirlukast tablets 10 mg tablets 20 mg tablets Singulair montelukast tablets 4 mg chewable tablets 1 time per sodium 5 mg chewable tablets day 10 mg coated tablets granules 4 mg packets Zyflo zileuton tablets 600 mg tablets 4 times Zyflo CR extended release tablets 5 yrs & AstraZeneca 12 mos & Merck & Co. Inc. Cornerstone Therapeutics Charts Updated August 18, 2010 Copyright 2010 All Rights Reserved Page 7