Prior Cargoes Restrictions for USP and NF Solvents Document date: 10 April 2015
PRIOR CARGO RESTRICTIONS AND POTENTIAL CONTAMINATION SOURCES. For solvents such as but not limited to: Monoproylene Glycol (MPG) USP/EP and Dipropylene Glycol Low Odour (LO) Acetone NF IPA USP Prohibited Adjacent Cargo and Prior Cargo List NOTE: Substances not on this list having a hazardous potential will be checked by Shell s Chemical Marine Technical Advisor, Product Steward or Quality Manager for further evaluation. This list is based in part on NIOP Unacceptable Prior Cargo List, FOSFA List of Banned Immediate Previous Cargoes and Codex Code of Practice for the Storage and Transport of Edible Fats and Oils in Bulk (Codex Alimentarius). The criteria described in the CEFIC Guidelines for Handling and Distribution of Propylene Glycol USP/EP for all shipments in non-dedicated transportation equipment to protect endusers from product cross-contamination has been applied (see chapter 5.3 of this guideline). Chemical substances highlighted in red are prohibited adjacent cargos. Non-highlighted chemical substances are allowed as an adjacent cargo only after prior notification to Shell. 2
SUBSTANCE REASON TO BE ON THE LIST Acetaldehyde Carcinogen cat 3 Acetic acid Acetone cyanohydrin Acrylamide Acrylic acid Acrylates (see individual products in the list) Strong acid Reactive with water. Decomposes to form Hydrogen Cyanide Carcinogen cat 2, sensitizer Corrosive Sensitizers Acrylonitrile Carcinogen cat 2 Adiponitrile Alkyl and Alkyl compounds Animal products including lard, tallow, etc. Aniline Toxic by ingestion. Very reactive Kosher Carcinogen and mutagen cat 3, sensitizer Anisol Mutagen cat 2. Ammonium Hydroxide Asphalt (paving asphalt, roofer s flux, etc.) Strong base Petroleum product Benzene including benzene mixtures Carcinogen cat 1 1,3-butadiene Butyl acrylate Caprolactam Carcinogen cat Sensitizer Harmful by all routes of exposure. Carbon tetrachloride Toxic by inhalation, carcinogen cat 3 Cardura E (trade name for glycidyl esters of versatic 911 acid) Cashew nutshell liquid Skin irritating and sensitizing properties Harmful by ingestion. Strong skin and respiratory sensitizer, symptoms may be delayed. Contact with eyes may cause permanent injury. 3
Chlorinated compounds (examples in the list) Chloro benzenes Chloroform Harmful by inhalation, aquatic toxicity Carcinogen cat 3, harmful by inhalation Chloroprene Carcinogen cat 2 Coal tar and coal tar pitch Carcinogen cat 2 Creosote (coal tar or wood) Carcinogen cat 2 Cresol (o,m,p and cresylates and cresylic acids) Corrosive, toxic if contact with skin Cyanates (see individual products in the list) Cyclohexane Dibutylamine 1,3-dichloropropene ( TELONE ) Diethanolamine Diethylenetriamine Diethylene glycol Diglycidyl ether of bisphenol A Diisopropylamine 1,2-Dimethoxyethane Solvent limitation Harmful by all routes of exposure harmful by all routes of exposure. Fumigant, NIOP list Formation of nitrosamines, harmful if swallowed (R 48) Corrosive, sensitizer Harmful if swallowed Digylcidylethers are suspected carcinogens; together with bisphenol A - > discussion on hormone disrupting effects Corrosive Solvent to limited Dimethylformamide (DMF) Reprox tox cat 2 Dioctyl phthalate Suspected carcinogen 1,4 Dioxane Solvent to be limited Diphenyl methane diisocyanate (MDI) Divinylbenzene Respiratory and skin sensitizer Intermediate, associated with styrene 4
Epichlorohydrin Epoxy resins (uncured) Ethanolamine Ethyl acrylate Ethylbenzene Ethyl hexyl acrylate Ethylene dibromide Carcinogen cat 3, corrosive, sensitizer Asthmogenic Corrosive, harmful by all routes of exposure Sensitizer IARC 2B See other acrylates Carcinogen cat 2, environmental tox Ethylene dichloride Carcinogen cat 2 Ethylenediamine Ethylene glycol (Monoethylene glycol MEG) Corrosive, sensitizer Harmful if swallowed Ethylene Glycol Ethers such as: Ethylene glycol ethyl ether (ethoxy ethanol), Ethylene glycol ethyl ether acetate (ethoxy ethyl acetate), Ethylene glycol methyl ether acetate (methoxy ethylacetate), Several health hazards including reproductive toxicity Ethylene glycol methyl ether (methoxy ethanol), Ethylene glycol monobutyl ether (butoxyethanol), Ethylene glycol monoalkyl ether) Ethylene oxide Carcinogen and mutagen cat 2 Formaldehyde Furfuryl alcohol Gasoline Gas oil Gluteraldehyde IARC 2A carcinogen Harmful by all routes of exposure; IARC review inadequate data Petroleum product (may contain benzene) Petroleum product (may contain benzene) Toxic by inhalation and if swallowed, sensitizer, very toxic to aquatic organisms 5
Hexamethylediamine Isoprene Isocyanates (TDI, MDI..) Kerosine Leaded petroleum or other leaded products (three previous cargos) Lube oil additives Methyl acrylate Corrosive Carcinogen cat 2, mutagen cat 3, harmful to aquatic organisms Asthmogenic, very reactive Petroleum product (may contain benzene) Petroleum product (may contain benzene) FOSFA list Sensitizer, harmful by all routes of exposure Methylene chloride Carcinogen cat 3 Methyl Isobutyl Ketone Methyl methacrylate monomer Methyl styrene monomer Methyl tertiary butyl ether Methylene diisocyanate (MDI) Methyl isocyanate Mineral oils Morpholine Morpholine ethanol Naphthalene IARC 2B Listing Sensitizer Odour threshold Odour threshold, irritant See isocyanates See isocyanates Petroleum product- skin and inhalation irritant Corrosive, harmful by all routes of exposure, IARC group 3 FOSFA list Carcinogen cat 3, toxic to aquatic organisms Nitrobenzene Carcinogen and reprotox cat 3 Nitropropane Noxious cargoes Perchloroethylene Harmful by all routes of exposure Ref NIOP Carcinogen cat 3, toxic to aquatic 6
organisms Pesticides including biocides, insecticides, fungicides, herbicides and rodenticides Phenol Phthalates Polymethylenene polyphenylisocyanate n-propylamine See CEFIC guidelines Mutagen cat 3, toxic by all routes of exposure, corrosive IARC concluded not a human carcinogen (group 3) (effects in lab animals related to peroxisome proliferation) See isocyanates Low odour theshold Propylene oxide Carcinogen and mutagen cat 2 Pygas Pyridine Sodium Hydroxide Styrene monomer Sulphuric acid Tall oil Tall oil fatty acid Tetrahydrofuran Toluene Toluene diisocyanate (TDI) Toluidine Transformer oil Trichloroethane Triethylene glycol Contains benzene Harmful by all routes of exposure, IARC group 3, low odour threshold Strong base IARC 2B, tainting, low odour threshold Strong acid NIOP list NIOP list Irritating, mutagenic/carcinogenic effects observed in animals Reprotox cat 3, neurotox effects See isocyanates IARC 2B FOSFA list (might contain PCB) Harmful by inhalation, ozone-depleting properties; chlorinated compound Falls into the group of glycols 7
Tricresyl phosphate Vinyl acetate monomer Under NTP review (cancer, reprotox) IARC 2B Vinyl chloride monomer Carcinogen cat 1 Xylene (mixed isomer and o-, m-, p-) Harmful by inhalation/skin contact, contains ethyl benzene Leaded products shall not be carried as the three previous cargoes. Ethylene Dichloride and Styrene Monomer shall not be carried as the three previous cargoes in organic coated tanks, or as the last cargo in stainless steel and inorganic coated tanks. Shell Chemical LP PO Box 4407 Houston Texas 77210 USA Tel +1 866 897 4355 Internet http://www.shell.com/chemicals Disclaimer The information contained in this publication is, to the best of our knowledge, true and accurate, but any recommendations or suggestions that may be made are without guarantee, since the conditions of use are beyond our control. Furthermore, nothing contained herein shall be construed as a recommendation to use any product in conflict with existing patents covering any material or its use. Shell Chemicals The expression Shell Chemicals refers to the companies of the Shell Group of companies that are engaged in the chemical businesses. Each of the companies that make up the Shell Group of companies is an independent entity and has its own separate identity. 8