Tingting Zhang Cell Phone: EDUCATION Ph.D. in Pharmacoepidemiology July 2013

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Tingting Zhang Tingting_zhang@brown.edu Cell Phone: 1-339-206-3938 EDUCATION Ph.D. in Pharmacoepidemiology July 2013 University of British Columbia Vancouver, Canada Dissertation: Asthma drug regimen optimality and health services utilization: a populationbased analysis in British Columbia, Canada M. Sc. in Population and Public Health December 2006 Simon Fraser University Burnaby, Canada Dissertation: Use and anticonvulsants in paediatrics 1996-2003 M.D. July 2005 Capital University of Medical Sciences Beijing, China RESEARCH FUNDINGS Assessing safety monitoring in patients taking oral multiple sclerosis treatments (ASYMPTOTE) Co-principal investigator C$286,694.37 Multiple Sclerosis Society of Canada September 2015 August 2018 Prescription drug use in patients with multiple sclerosis, Multiple Sclerosis Society of Canada Co-investigator May August 2015 Impact of adherence to immunomodulatory therapies on MS progression Postdoctoral Fellowship Award, Multiple Sclerosis Society of Canada Co-principal investigator July 2014 July 2016 Asthma drug regimen optimality and health services utilizations: a population-based analysis Drug Safety and Effectiveness Cross-Disciplinary Training Award Canadian Institutes of Health Research Co-principal investigator April 2010 March 2011 HONORS AND AWARDS Postdoctoral Fellowship Award, Multiple Sclerosis Society of Canada July 2014 July 2016 Travel award for the Alberta endms Retreat 2013: All About Teamwork September 2013 Travel award, Canadian Society of Pharmacology and Therapeutics July 2010 Child & Family Research Institute Research Methodology Training Grant July August 2009 Canadian Association for Population Therapeutics Studentship Award August 2008 University of British Columbia Entrance Scholarship September 2007 British Columbia Child and Youth Health Research Network Internship May September 2007 British Columbia Medical Association Summer Research Scholarship May September 2006 Simon Fraser University Graduate fellowship September 2005 April 2006 1

PUBLICATIONS Peer-Reviewed Journal Papers Zhang T, Tremlett H, Tennakoon A, Leung S, Zhu F, Kingwell et al. Examining the effects of comorbidities on disease-modifying therapy use in multiple sclerosis. Neurology.2016;86:1287-95. Zhang T, Kingwell E, Hilda DJ, Zhu F, Zhao Y, Carruthers R et al. Association between selective serotonin reuptake inhibitors use and multiple sclerosis disability progression. Published online. Pharmacoepidemiology & Drug Safety. May 23, 2016. Bardal S, Smith A, Luo H, Zhang T, Groeneweg G, Jimenez Mendez R et al. Asthma in British Columbia: are we finally breathing easier? A population-based study of the burden of disease over 14 years. Published online. Journal of Asthma. July 14, 2016. Zhang T, Shirani A, Zhao Y, Ehsanul Karim M, Gustafson P and Petkau J et al. Exposure to beta-interferon and onset of secondary progressive multiple sclerosis. European Journal of Neurology. 2015; 22(6):990-1000. Zhang T, Smith A, Camp P and Carleton B. High use of health services in patients with suboptimal asthma drug regimens: a population-based assessment in British Columbia, Canada. Pharmacoepidemiology & Drug Safety. 2013 Jul;22(7):744-51. Zhang T, Smith A, Camp P, MacLeod S and Carleton B. Prescription drug dispensing profiles for one million children: a population-based analysis. Eur J Clin Pharmacol. 2013 Mar;69(3):581-8. Camp P, Zhang T, Smith A and Carleton B. The use of long-acting beta2-agonists as monotherapy in children and adults. Journal of Population Therapeutics and Clinical Pharmacology. 2013;20(1):e1-e12. Chawla J, Seear M, Zhang T, Smith A and Carleton B. Fifty years of pediatric asthma in developed countries: how reliable are the basic data sources? Pediatric Pulmonology. 2012;47(3):211-9. Zhang T, Carleton B, Smith A and Prosser R. The Added Burden of Comorbidity in Patients with Asthma. Journal of Asthma. 2009;46(10):1021-6. Conference Proceedings Jimenez-Mendez R, Zhang T, Smith A and Carleton B. Changing asthma regimens from suboptimal to optimal: what are the impacts on health service use in patients with asthma? Pharmacoepidemiology and Drug Safety. 2011;20(S1):s253. 2

Zhang T, Smith A, Prosser R, and Carleton B. Asthma drug regimens and health service utilization: what impact do changes in the optimal use of medication have on children with asthma. Basic & Clinical Pharmacology & Toxicology. 2010;107(s1):s685. Zhang T, Li Z, Smith A, Cao D, Carleton B. Pharmacoepidemiological studies in Chinese and Canadian children lack of comprehensive data a major limitation. Basic & Clinical Pharmacology & Toxicology. 2010,107(S1):s686. Zhang T, Smith A, Camp P, Carleton B. Asthma Drug Regimens and Health Service Utilization: How Can We Improve Care? Am. J. Respir. Crit. Care Med. 2010; 181: A3125. Zhang T, Carleton B, Smith A and Prosser R. Changing patterns of asthma patients medication regimens and health service utilization: a population-based study. Journal of Population Therapeutics and Clinical Pharmacology. 2008;15(3):e744. Prosser B, Carleton B, Smith A and Zhang T. Prescription medication utilization in British Columbia s pediatric population. Journal of Population Therapeutics and Clinical Pharmacology. 2008;15(3):e668. OTHER PRESENTATIONS Zhang T, Tremlett H, Tennakoon A, Leung S, Zhu F, Kingwell et al. Examining the effects of comorbidities on disease-modifying therapy use in multiple sclerosis. The British Columbia MS/NMO Connect Presentation. June 2015. Zhang T, Shirani A, Zhao Y, Ehsanul Karim M, Gustafson P and Petkau J et al. Beta-interferon exposure and onset of secondary progressive multiple sclerosis. The British Columbia MS/NMO Connect Presentation. April 2015. Zhang T, Carleton B, Smith A and Prosser R. Drug Utilization in the Pediatric Population of British Columbia: A Comparison with a National Study. Third Annual Conference & AGM Leaders, Innovators & Healers in Child and Youth Health Research, Vernon, British Columbia, Canada, November 2008 (Invited presentation). WORK EXPERIENCES Assistant Professor Brown University Department of Health Services, Policy & Practice School of Public Health August 2016 - present Post-Doctoral Fellow University of British Columbia Pharmacoepidemiology in Multiple Sclerosis Faculty of Medicine, Department of Medicine (Neurology) August 2013 July 2016 3

Co-lead nine research projects on multiple sclerosis risk factors, disease progression, treatment outcomes, using population-based health administrative data and clinical data; responsible for study design, statistical analysis, presentation of findings to internal team members and cross-country collaborators. Co-lead multiple grant applications and received funding from Multiple Sclerosis Society of Canada. Research Assistant University of British Columbia September 2007 Jul 2013 Pharmaceutical Outcomes Programme (POPi) Co-investigators of three research projects on health services utilization research in asthma. Responsible for study design, analytical plan preparation, data analysis, presentation of findings to team members, data organizations for epidemiological projects in the group and providing training of using population-based data for analysis. Accomplished five publications (first author of 3), and presented research findings in 5 national and international conferences Research Assistant Simon Fraser University January March 2006 Cardiac Program, St. Paul s Hospital Participated in literature review and data collection for the cardiovascular disease prevention project-prospective urban and rural epidemiology (PURE) study Research Assistant Beijing Anzhen Hospital, China July August 2003 Department of Epidemiology, Cardiovascular and Lung Blood Research Institute affiliated to Capital University of Medical Sciences. Responsible for survey data entry and descriptive analysis for the project - antibiotics used in patients with severe acute respiratory syndrome (SARS) or suspected SARS. TEACHING AND MENTORING EXPERIENCES Summer Student Supervisor Faculty of Medicine/Neurology, University of British Columbia May-August 2015 Supervised the 1 undergraduate student s research project prescription drug use prior to MS diagnosis. Research Assistant Mentor Faculty of Medicine/Neurology, University of British Columbia May - August 2015 Main activities: guide manuscript formatting, online submission, and grant application preparation and online submission procedures. Junior Statistician Mentor Child & Family Research Institute, Children s Hospital January - December 2012 Main activities: provide instructions of health administrative data to junior statisticians recruited 4

in the research group, and guide data cleaning and analysis procedures. NON-ACADEMIC VOLUNTEER Translator Life Sciences British Columbia July 2013 Assisted the China Pharmaceutical Industry Research and Development Association (SINO-PhIRDA) delegation to understand presentations by BC biomedical companies and communications with company representatives. Coordinator of Pharmacoepidemiology Journal Club October 2009 September 2010 Faculty of Pharmaceutical Sciences, University of British Columbia Organized and coordinated the Pharmacoepidemiology Journal Club. Program Assistant - Child & Family Research Institute June - July 2006 Assisted the organization of the 15 th World Congress of Pharmacology-International Challenges in Pediatric Pharmacology. Translated all presentation slides and assisted the communications between researchers in the conference. CERTIFICATE Certificate of Training in Intermediate and Advanced Pharmacoepidemiology McGill University, Canada July 2009 5