Challenges of Incorporating Functional Ingredients into Foods - An NPD and Analytical Perspective

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Challenges of Incorporating Functional Ingredients into Foods - An NPD and Analytical Perspective Jane Staniforth & Robert Griffiths Customer Focused, Science Driven, Results Led

Overview Introduction to RSSL What is meant by Functional Ingredients? The development brief Analytical considerations Case studies

What Do We Do at RSSL? We provide science and technology outsourcing to the global food, healthcare and pharmaceutical industries Key areas of expertise for food sector include: Functional Foods & Ingredients Allergens Analysis & Consultancy Contaminant Investigative Analysis Product Development

Definition of Functional Ingredient Ingredients that provide some health benefit above and beyond fulfilling basic nutrition (healthpromotion) Vitamins Antioxidants Minerals Omega-3 Proteins Plant sterols

Challenge Your Development Brief What Where What is the product? What functional ingredients are to be added? What claims do you want to make? What is the target shelf life? Where will it be manufactured? Where will the product be stored? When When is product due to be launched? When is product to be consumed? How often? Who Who is target retailer? Who is the target consumer?

Key Challenge Know what product you want. but more importantly know what product you do not want

Challenges For The Developer Scrutinise original concept Sensory attributes Choice of ingredient(s) Quality of ingredient / supplier Active levels Incorporation of active/raw material Stability of ingredient & product Storage conditions Packaging

Why Analyse? Raw material assessment Development process Label claims Shelf life Troubleshooting Due diligence

Challenges For Analysts Sampling Stability Active form Method selection Extraction Sensitivity Speed, robustness

Case Study: Omega 3 & 6 Fatty Acids

Development Challenges Select the optimum source of active Flavour selection Taste optimisation Consider how being consumed

Analytical Challenges Source of ingredient Component of interest Is the product fortified? Form of ingredient Nature of finished product Ingredient stability

Outline of Method Sampling Extraction Derivatisation Instrumentation GC Results

Case Study: Botanicals

Challenges Are you claiming an amount of active or plant extract? Botanical Green Tea Guarana Echinacea Pomegranate Soy Ginseng Active Catechins Caffeine Chlorogenic acid Ellagic acid Isoflavones Ginsenosides Are you are looking at a mixture of botanicals? Carotenoids methodology vs forms Stability of active

Example of Chromatography Of Markers Used For Stability mau 800 DAD1 B, Sig=220,4 Ref=590,20 (I:\ANP_VNP\NATPROD1\DATA\NB28126\008-0901.D) 700 600 500 400 300 24 months 200 100 0 0 10 20 30 40 50 min mau DAD1 B, Sig=220,4 Ref=590,20 (I:\ANP_VNP\NATPROD1\DATA\SAL21125\122517.D) 700 600 500 400 300 12 months 200 100 0 0 10 20 30 40 50 min mau DAD1 B, Sig=220,4 Ref=580,40 (I:\ANP_VNP\NATPROD2\1\DATA\VAL2515\12815'1.D) 1000 800 600 400 0 months 200 0 0 5 10 15 20 25 30 35 40 45 min

Lots to consider to ensure a successful product

Get The Most Out Of Your NPD Team Development Support: Ensure development brief is very specific and achievable Incorporate the correct amount of ingredient to make any claims Start analytical validation and checking at the earliest point possible

Get The Most Out Of Your Analyst Analytical Support: Consult at early stage Check method available Ingredient details Product information Homogenous sample Transport of sample Manufacturing process

Ensure your expectations.. and the abilities of your partner organisation.. are matched

Future Challenges New forms of ingredients Legislation changes New products Increased dosage Combinations of ingredients Method developments Media attention

Any Questions? Thank You For Your Attention Jane Staniforth & Robert Griffiths Jane.Staniforth@rssl.com Robert.G.Griffiths@rssl.com