DSI S.r.l. DSI S.r.l. is one of the European leaders in the field of immunodiagnostic tests manufacturing. We are a research-focused company with the long-term microbiological scientific traditions. Our fundamental task is to continuously apply cutting-edge biotechnologies to benefit patients. Today the company has a multinational workforce of over 400 employees, including more than 50 highly educated researchers: PhD biologists, chemists and medical doctors. DSI is one of the major players in the development of tests for the diagnosis of infectious diseases and hormone pathologies. The manufacturing facilities are specially designed for ELISA kits production and generating of recombinant proteins for use as diagnostic kits components. Main lines of activity are: ELISA kits for infections (HIV; Hepatitis A, B, C, D, E; Syphilis, ToRCH and others), hormone pathologies and tumor markers. Bacteriology - routine microbial identification, which is applied in food processing, water treatment and public healthcare. Recombinant antigens (HAV, HBV, HCV, HDV, HEV, Syphilis, HIV, HSV, CMV, EBV, VZV, HTLV, Toxo, SARS, HHV 8, TBE, Chlamydia), antibodies, and conjugates (HRP and biotin labeled) Quality Control Materials DSI offers technical support for all the clients regardless of their location. DSI s major advantage is traditionally high performance characteristics of kits, recognized not only by our customers, but also by PEI, CDC researchers and other independent authorities. Another priority of the company is top-level customer service: we provide technical support worldwide and constantly improve our kits, taking into consideration customers' feedback. DSI Srl Via A.Volonterio, 36a, Saronno, Milan, 21047, Italy Phone: +39 02 967 09111 +39 02 967 04235 Fax: +39-029620185 E-mail: info@dsitaly.com
(min)* Sensitivity HIV DS-EIA-ANTI-HIV-UNIF (Ab) I-153 96 115 24 DS-EIA-ANTI-HIV-UNIF (Ab) I-150 192 115 24 DS-EIA-ANTI-HIV-UNIF (Ab) I-155 480 115 24 DS-EIA-HIV-AG-SCREEN I-1452 96 115 12 0.025 IU/ml DS-EIA-HIV-AGAB-SCREEN I-1654 96 80(s) or 105(i) 24 (p24) 0.5 IU/ml DS-EIA-HIV-AGAB-SCREEN I-1652 192 80(s) or 105(i) 24 (p24) 0.5 IU/ml DS-EIA-HIV-AGAB-SCREEN I-1656 480 80(s) or 105(i) 24 (p24) 0.5 IU/ml DS-EIA-HIV-AB/AG-SPECTRUM I-751 16 85(s) or 140(i) 18 (p24) 0.25 IU/ml DS-EIA-HIV-AG+AB I-2654 96 80(s) or 105(i) 24 (p24) 0.25 IU/ml DS-EIA-HIV-AG+AB I-2652 192 80(s) or 105(i) 24 (p24) 0.25 IU/ml DS-EIA-HIV-AG+AB I-2655 480 80(s) or 105(i) 24 (p24) 0.25 IU/ml HAV DS-EIA-ANTI-HAV-G-RECOMB A-151 96 80 18 DS-EIA-ANTI-HAV-M-RECOMB A-251 96 80 15 HBV HBsAg DS-EIA-HBsAg B-1154 96 105(s) or 145(i) 24 0.05 IU/ml (s) DS-EIA-HBsAg B-1152 192 105(s) or 145(i) 24 0.05 IU/ml (s) DS-EIA-HBsAg B-1155 480 105(s) or 145(i) 24 0.05 IU/ml (s) DS-EIA-HBsAg (confirmatory) B-1156 48 105(s) or 145(i) 24 0.05 IU/ml (s) DS-EIA-HBsAg-0.01 B-1254 96 80(s) or 140(i) 24 0.01 IU/ml DS-EIA-HBsAg-0.01 B-1252 192 80(s) or 140(i) 24 0.01 IU/ml DS-EIA-HBsAg-0.01 B-1255 480 80(s) or 140(i) 24 0.01 IU/ml DS-EIA-HBsAg-0.01 (confirmatory) B-1256 48 80(s) or 140(i) 24 0.01 IU/ml EIA-HBsAg-confirmatory test B-231 200 24 DS-ERYTHRO-HBsAg B-431 200 60 24 Hepatitis B markers DS-EIA-HBeAg B-951 96 90 18 DS-EIA-ANTI-HBc B-653 96 90 15 DS-EIA-ANTI-HBc B-650 192 90 15 DS-EIA-ANTI-HBe B-851 96 90 24 DS-EIA-ANTI-HBsAg B-551 96 85(s) or 115(i) 15 EIA-ANTI-HBc-M-SCREEN B-753 96 60 15 2 * (s) - shaker (i) - incubator Common reagents: WS, SR, SB
(min) HCV EIA-ANTI-HCV C-153 96 100(s) or 110(i) 24 EIA-ANTI-HCV C-150 192 100(s) or 110(i) 24 EIA-ANTI-HCV C-155 480 100(s) or 110(i) 24 DS-EIA-ANTI-HCV-SPECTRUM GM (4-wells) C-451 24 120 15 DS-EIA-ANTI-HCV-SPECTRUM GM (4-wells) C-455 120 120 15 DS-EIA-ANTI-HCV-SPECTRUM GM (2-wells) C-452 48 120 15 EIA-ANTI-HCV-SPECTRUM-G C-351 24 120 15 EIA-ANTI-HCV-SPECTRUM-M C-352 24 90 15 EIA-ANTI-HCVc-M C-253 96 90 24 DS-EIA-ANTI-HCV-AVIDITY C-651 48 128 15 DS-EIA-HCV-AGAB C-1952 96 75 13 DS-EIA-HCV-AGAB C-1953 192 75 13 DS-EIA-HCV-AGAB C-1954 480 75 13 DS-EIA-HCV-AG C-1962 96 75 13 DS-EIA-HCV-AG C-1963 192 75 13 DS-EIA-HCV-AG C-1964 480 75 13 HDV EIA-ANTI-HDV D-152 96 80 15 EIA-ANTI-HDV-M D-252 96 110 15 HEV DS-EIA-ANTI-HEV-G E-151 96 80 15 DS-EIA-ANTI-HEV-M E-152 96 80 15 Syphilis EIA-ANTI-LUES-GM L-155 96 90 15 EIA-ANTI-LUES-GM L-154 192 90 15 EIA-ANTI-LUES-GM L-156 480 90 15 EIA-ANTI-LUES-G L-153 96 90 15 EIA-ANTI-LUES-M L-253 96 90 15 DS-TPHA-ANTI-LUES L-431 100 45 18 DS-TPHA-ANTI-LUES L-432 200 45 18 LUES-TEST (analogue of RPR-test) L-332 500 10 18 Malaria DS-EIA-MALARIA ML-2062 96 50 15 - C mark coming soon Common reagents: WS, SR, SB (HCV and Syphilis kits have common TMB) 3
(min) Format * ToRCH Herpes DS-EIA-ANTI-HSV-1,2-G H-151 96 80 15 Qlt/Sqnt DS-EIA-ANTI-HSV-1,2-G-AVIDITY H-152 48 90 15 DS-EIA-ANTI-HSV-2-G H-251 96 80 15 Qlt/Sqnt DS-EIA-ANTI-HSV-2-G-AVIDITY H-252 48 90 15 Epstein-Barr Virus DS-EIA-ANTI-EBV-VCA-G H-351 96 80 24 Qlt DS-EIA-ANTI-EBV-VCA-G-AVIDITY H-352 48 90 24 DS-EIA-ANTI-EBV-VCA-M H-353 96 80 24 Qlt DS-EIA-ANTI-EBV-EA-G H-354 96 80 24 Qlt DS-EIA-ANTI-EBV-EBNA-G H-355 96 80 24 Qlt Toxoplasmosis DS-EIA-ANTI-TOXO-G T-151 96 80 15 Qlt/Qnt DS-EIA-ANTI-TOXO-G-AVIDITY T-152 48 90 15 DS-EIA-ANTI-TOXO-A T-154 96 80 24 Qlt DS-EIA-ANTI-TOXO-M T-153 96 80 24 Qlt DS-EIA-ANTI-TOXO-M (capture) T-1153 96 110 15 Qlt Cytomegalovirus DS-EIA-ANTI-CMV-G CM-151 96 75 15 Qlt/Qnt DS-EIA-ANTI-CMV-G-AVIDITY CM-152 48 85 24 DS-EIA-ANTI-CMV-M CM-153 96 75 24 Qlt DS-EIA-ANTI-CMV-M (capture) CM-1592 96 85 15 Qlt Rubella DS-EIA-ANTI-RUBELLA-G Ru-151 96 120 15 Qlt/Qnt DS-EIA-ANTI-RUBELLA-G-AVIDITY Ru-152 48 130 15 DS-EIA-ANTI-RUBELLA-M Ru-153 96 120 15 Qlt Chlamydia DS-EIA-ANTI-CHLAMYDIA-TR-G X-1151 96 70 15 Qlt/Sqnt DS-EIA-ANTI-CHLAMYDIA-TR-A X-1251 96 70 15 Qlt/Sqnt DS-EIA-ANTI-CHLAMYDIA-TR-M X-1351 96 70 24 Qlt * Qlt - Qualitative (detects if the sample is positive or negative) Qnt - Quantitative (determinates the concentration of marker in the sample) Sqnt - Semiquantitative (determinates positive titre by using the table mentioned in IFU) 4 Common reagents: WS, SR, SB
(min) Common SD * FAST-ToRCH Herpes DS-EIA-ANTI-HSV-1/2-G-FAST H-1492 96 35 15 DS-EIA-ANTI-HSV-1/2-M-FAST H-1502 96 40 15 DS-EIA-ANTI-HSV-1-G-FAST H-1452 96 35 15 DS-EIA-ANTI-HSV-1-M-FAST H-1472 96 40 15 DS-EIA-ANTI-HSV-2-G-FAST H-1462 96 35 15 DS-EIA-ANTI-HSV-2-M-FAST H-1482 96 40 15 Toxoplasmosis DS-EIA-ANTI-TOXO-G-FAST T-1532 96 35 15 DS-EIA-ANTI-TOXO-M-FAST T-1552 96 70 15 Cytomegalovirus DS-EIA-ANTI-CMV-G-FAST CM-1522 96 35 15 DS-EIA-ANTI-CMV-M-FAST CM-1512 96 40 15 Rubella DS-EIA-ANTI-RUBELLA-G-FAST Ru-1582 96 35 15 DS-EIA-ANTI-RUBELLA-M-FAST Ru-1542 96 70 15 THE ADVANTAGES OF FAST-TORCH KITS FAST : IgG 35 min IgM 40 min (HSV, CMV) 70 min (To, Ru) EASY performed at room temperature without additional equipment CONVENIENT reagents are common and ready-to-use Common reagents: WS, SR, TMB * Kits marked with the same color have common SD 5
incubation time (min) Detection limit Range Hormones and Tumor markers Thyroid gland markers DS-EIA-Thyroid-TSH TH-351 96 135 18 0.05 μiu/ml 0 32 μiu/ml DS-EIA-Thyroid-T3 total TH-152 96 105 15 0.2 ng/ml 0 9,0 ng/ml DS-EIA-Thyroid-T3 free TH-151 96 80 (shaker) 18 0.25 pg/ml 0 20 pg/ml DS-EIA-Thyroid-T4 total TH-252 96 105 18 5 nmol/l 0-400 nmol/l DS-EIA-Thyroid-T4 free TH-251 96 85 15 1 pmol/l 0 90 pmol/l DS-EIA-Thyroid-Thyroglobulin TH-651 96 85 (shaker + 37 0 C) 18 1.5 ng/ml 0 300 ng/ml DS-EIA-Thyroid-anti-TG TH-451 96 130 15 10 IU/ml 0 2000 IU/ml DS-EIA-Thyroid-anti-TPO TH-551 96 130 15 2 IU/ml 0 500 IU/ml Fertility hormones DS-EIA-Steroid-Cortisol EH-151 96 85 18 5 nmol/l 0 1800 nmol/l DS-EIA-Steroid-Progesterone RH-351 96 115 15 0.5 nmol/l 0 100 nmol/l DS-EIA-Steroid-Testosterone RH-353 96 55 (shaker + 37 0 C) 18 0.2 nmol/l 0 40 nmol/l DS-EIA-Gonadotropin-LH RH-152 96 105 18 0.3 miu/ml 0 100 мiu/ml DS-EIA-Gonadotropin-FSH RH-151 96 105 18 0.3 miu/ml 0 100 мiu/ml DS-EIA-Gonadotropin-hCG RH-153 96 115 18 1 miu/ml 0 500 мiu/ml DS-EIA-Prolactin RH-251 96 105 18 10 miu/ml 0 4500 мiu/m Tumor markers DS-EIA-AFP CH-251 96 150 18 1 IU/ml 0 300 IU/ml DS-EIA-PSA total CH-151 96 100 15 0.3 ng/ml 0 45 ng/ml DS-EIA-PSA free CH-152 96 145 15 0.1 ng/ml 0 10 ng/ml DS-EIA-CA 125 CH-1832 96 115 15 1 U/ml 0 500 U/ml Controls are included into the kit. All the kits are performed at RT without shaker if other is not mentioned Name Cat. ID Test Common reagents: WS, SR, TMB (min) Notes Other ELISA-kits DS-EIA-ANTI-TBEV-M K-251 96 120 15 Tick-borne encephalitis DS-EIA-ANTI-TBEV-G K-151 96 120 15 Tick-borne encephalitis DS-EIA-ANTI-SARS-CoV S-151 96 80 15 SARS DS-EIA-RF RF-151 96 80 15 Rheumatoid factor DS-EIA-RF-M RF-153 96 80 15 Rheumatoid factor DS-EIA-IgE total ET-151 96 60 15 IgE total DS-ERYTHRO-MYOGLOBIN M-131 60 20 24 Myoglobin 6
QCPQQQQQQQQCP Performance panels (Standard panels, Control panels) are intended for evaluation of assays performance and estimation of quality of laboratory research. Panels contain several vials (see table for details) with inactivated lyophilized positive and negative samples. The characteristics of each sample are presented in certificates of analysis for each lot. Marker Cat. ID Pos, vials Neg, vials anti-hav-igm A-331 9 6 24 HBsAg (0.01-1.0 IU/ml) B-1031 6 2 24 anti-hbc B-1631 8 8 24 anti-hcv C-531 5 3 24 anti-hev-g E-331 6 6 24 anti-ebna-igg H-1031 4 6 24 anti-ebv-vca-igg H-1131 5 2 24 anti-ebv-ea-igg H-1231 4 6 24 anti-hhv-8-igg H-431 4 6 24 anti-cmv-igg CM-331 10 4 24 anti-tbe-igg K-331 6 6 24 anti-hcv C-0380 20 8 24 HIV-1 Ab (+) I-1620 16 0 24 HIV-1,2 Ab (-), HIV-1 Ag p24 (-) I-1610 0 20 24 HIV-2 Ab (+) I-1970 8 8 24 Standard Ab IgG(+/-) Ch. Trachomatis X-1600 8 8 24 Standard samples are intended for control of quality and detection of sensitivity limit of assay. Panels contain lyophilized samples and reagent for dilution. Name Cat. ID Marker Concentration DS-HBsAg-SS B-0350 HBsAg 20 IU/ml 5 years DS-SS-HIV-1 Ag p24 (+) I-1030 HIV-1 Ag p24 200 pg/ml 3 years DS-SS-HBeAg B-2030 HBeAg 100 U 5 years DS-SS-anti-HBc B-2040 anti-hbc 100 U 5 years DS-SS-anti-HBcM B-2050 anti-hbcm 100 U 2 years Quality assessment panels are intended for internal laboratory quality assessment of EIA-procedure for presence of required infection marker (assessment of convergence, reproducibility, for detection of systematic and accidental errors). Panels contain inactivated lyophilized serum (plasma) sample positive for required infection marker. Name Cat. ID Vials DS-QA-HBsAg B-1431 24 24 DS-QA-ANTI-HCV C-731 24 24 DS-QA-HIV-Ag (p24) I-931 24 24 DS-QA-ANTI-HIV-1 I-831 24 24 DS-QA-ANTI-LUES L-531 24 24 Panel of samples containing mutant variants of HBsAg Panel contains 26 vials (2 for each mutant form) Name Cat. ID Vials Panel of samples containing mutant variants of HBsAg subtypes ayw1 and adw2 B-1531 26 24 7
BACTERIOLOGY Name and description Cat. ID Test Test time Enterobacteria Enterobacteria biochemical differential panel Kit for routine enterobacteria type identification by 20 biochemical characteristics P - 131 20 18-24h 12 Code catalogue (Enterobacteria differential panel) P - 231 1 brochure DS-DIF-ENTERO-12 Kit of reagents for routine enterobacteria type identification by 12 biochemical characteristics. The kit includes 3 breakable microplates that can be used for 24 times over a shelf life. P - 731 24 18-24h 12 DS-DIF-ENTERO-24 Kit of reagents for routine enterobacteria type identification by 24 biochemical characteristics. The kit includes 6 breakable microplates that can be used for 24 times over a shelf life. DS-DIF-SALMONELLA Kit of reagents for routine enterobacteria identification and interspecific differentiation of Salmonella by 8 biochemical characteristics DS-OXIDASE Kit is intended for the detection of bacterial cytochrome oxidase. The package contains 10 test strips enabling 50 determinations P - 1441 24 24h 12 P -1431 24 24h 12 PO - 132 50 up to 30 sec 24 Staphylococci Staphyllococcus biochemical differential panel Kit for routine staphyllococcus type identification by 17 biochemical characteristics P - 431 20 18-24h 12 Code catalogue (Staphyllococcus differential panel) P - 531 1 brochure Corynebacteria DS-DIF-CORYNE Kit for routine Corynebacterium type identification by 9 biochemical characteristics and determination of toxigenicity P - 1031 12 16-24h toxigenicity: 48h 12 Non-fermentative bacteria DS-DIF-NONFERM Biochemical assay for routine identification and interspecific differentiation of gram-negative nonfermentative bacteria. The kit includes 3 breakable microplates that can be used for 24 timer over shelf life EasyBac Software for automatic identification of bacteria PN-732 24 48h 12 P-1131 1 CD Legend: WS - Washing Solution SR - Stop Reagent (can be used as the common reagent if the molarity is the same) SD - Sample Diluent SB - Substrate Buffer 8 Revision 009 from 07.02.2014