COMPANY INTRODUCTION: PROFILE & PRODUCTS
CONFIDENTIALITY AGREEMENT The information and images contained in this presentation are confidential and may constitute inside information, it is intended only for the use of the addressee. It is the property of ENDOCOR, unauthorized use, disclosure, or copying of this communication or any part thereof is strictly prohibited and may be unlawful. 2
OUTLINE Our Story Our Approach Our Products Our Markets Our Distributers Our Network 3
BORN TO INNOVATE EXTEND ENHANCE L I F E ENDOCOR s synergy and innovation was born out of an incorporation in Hamburg (Germany), that brought together individuals from across the spectrum - scientists, business moguls, and renowned physicians, who shared the same dream, the same vision and the same drive to innovate, to extend and to enhance life. 4
WHAT WE DO ENDOCOR develops, manufactures and markets a full line of cutting edge coronary and peripheral medical devices along with interventional kits and accessories, for the treatment of complications from cardiovascular and endovascular disease. 5
OUR HOME HAMBURG We are headquartered in the heart of the free and hanseatic city of Hamburg (Germany) with our office in the Finnlandhaus iconic building. Our state-of-the-art manufacturing facilities are strategically located on the outskirts of Hamburg (Germany). 6
OUR MISSION At ENDOCOR, we strive to provide our clients with quality, innovation and superior customer service through product solutions that help manage complications of cardiovascular disease. We take pride in helping patients prevail over their disease while extending and enhancing their life. OUR VISION To be a leader and innovator in cutting edge less-invasive medical devices by developing and marketing products, training and treatment options. 7
OUR APPROACH Science Based Innovation Driven Customer Oriented Quality Focused 8
FUNDEMENTALS Scientific We have physicians that sit at the heart of our organization, creating a direct channel between evidence based science and product development. Innovative We are driven by innovation, therefore we committed our resources to leading the next generation of stent technology: biodegradable products. 9
FUNDEMENTALS Quality Focused We are focused on quality and integrate it in every step of the way, so we can provide our customers with quality made-in-germany medical devices. Customer Oriented We are firm believers that customers come first; whether its patients, doctors, hospitals, or our distributers, we cater to ensure the best customer satisfaction. 10
PRODUCT OVERVIEW Current Products (CE Marked and ISO Certified) Coronary Application Drug Eluting Stents Bare Metal Stents Drug Eluting Balloons PTCA Balloons Thrombus Removing Catheter Customized Interventional Kits Peripheral Application Nitinol Self-expandable Stents Drug Eluting Balloons PTA Balloons Customized Interventional Kits 11
CORONARY PRODUCTS Item Product Name Product Type Indication Area Regulatory Status Coronary Application Area 1.1 PRODIGY Paclitaxel Drug Eluting Stent on a Biostable Polymer Coronary Angioplasty CE Approved 1.2 CONSTELLATION Cobalt Chromium Stent Implementation System 1.3 SPIRIT Stainless Steel Stent Implementation System Coronary Angioplasty Coronary Angioplasty 1.4 AVANT Drug Eluting Balloon Coronary Angioplasty 1.5 CARDIOGLIDE PTCA Balloon Coronary Angioplasty 1.6 PHANTOM Thrombus Removing Aspiration Catheter System Coronary Angioplasty CE Approved CE Approved Coming Soon CE Approved CE Approved 1.4 CARDIO KITS Customized Interventional Kits Cardiology CE Approved 12
PRODIGY TM Paclitaxel Drug-Eluting Coronary Stent Patented cell design for consistent vessel coverage and support Excellent radial strength and conformability Highly flexible & low profile catheter with low profile navigation of tortuous anatomy Coated with Paclitaxel the optimum antiproliferative drug with long clinical history of efficacy High-tech balloon technology for smooth & effortless deliverability of the stent with added pushability and traceability 13
CONSTELLATION TM Cobalt Chromium Coronary Stent Highly flexible catheter with low profile navigation Excellent pushability and traceability High tech balloon for effortless deliverability 14
PERIPHERAL PRODUCTS Item Product Name Product Type Indication Area Regulatory Status Peripheral Vascular Application Area 1.1 DISCOVERY Nitinol Self Expandable Stent Peripheral Stenosis 1.2 ENDOGLIDE PTA Balloon Peripheral Stenosis 1.3 ENDO KITS Customized Peripheral Vascular Intervention Kits Peripheral CE Approved CE Approved CE Approved 15
DISCOVERY TM Nitinol Self-Expandable Peripheral Stent Nitinol stent with tantalum markers provides excellent visibility under fluoroscopy Minimal foreshortening ensures accurate positioning and placement Highly flexible & low profile catheter with low profile navigation of tortuous anatomy High resistance against bending, torsion and compression Single handed delivery catheter ensures 1:1 delivery 16
ENDOGLIDE PTA Catheter TM High strength balloon material optimizes wall strength through quint fold process Minimum crossing profile ensures smooth and effortless crossing Improved dual lumen shaft technology Robust catheter profile for improved pushability and traceability Specially engineered hydrophilic coating ensures glidability, minimalizes friction whilst avoiding slippage Rapid inflation and 17 deflation time
PIPELINE - BIODEGRADABLES Item Product Name Product Type Regulatory Status/Time 1.1 TBD Biodegradable Pulmonary Stent 2012 1.2 TBD Biodegradable Biliary Stent 2012 1.3 TBD Visible Balloons Under Fluoroscopy 2012 1.4 TBD Biodegradable Covered ES & Pulmonary Stent with Delivery Device 2012 1.5 TBD Biodegradable Cricoid 2013 1.6 TDB Biodegradable Colonic Stent 2013 1.7 TBD Anastomic Colonic Stent for Low Anterior Resections 2013 18
PIPELINE - CARDIOLOGY Item Product Name Product Type Regulatory Status/Time 1.1 SEQUENCE Sirolimus Drug Eluting Stent on a Fast Absorbing Biodegradable Polymer 1.2 TBD CTO Device for Chronic Occlusions in Coronary Arteries 1.3 TBD PTCA Balloon with Special Illumination Features 2012 2012 2012 1.4 TBD Perforation Management Device 2012 1.5 TBD Grow Stent for Coartations 2012 1.6 TBD Specialty Aortic Aneurysm Device 2013 19
PIPELINE PERIPHERAL Item Product Name Product Type Regulatory Status/Time 1.1 TBD Ultra Thin Profile PTA Balloons 2012 1.2 TBD Balloon Expandable Peripheral Vascular Stent 1.3 TBD PTA and Drug Eluting Balloons with Special Illumination Features 2012 2012 1.4 TBD Cartoid Self Exandable Stent 2012 1.5 TBD Cartoid Filter for Particle Entrapment 2012 1.6 TBD Paclitaxel Drug Eluting Stent 2013 20
OUR MARKETS In Germany and Western Europe, ENDOCOR is engaged in a direct sales channel through a highly professional and trained sales force. In other parts of the world, ENDOCOR relies upon its close relationships with its distributors to achieve its export goals. 21
OUR DISTRIBUTORS At ENDOCOR, we know our global sales success depends on our close relationship with distributors from across the world. Therefore, we engage in an contractual agreement for each country, with a well established medium-to-big sized distributer. And together, we work closely to establish our brand in the region and drive sales to achieve our goals. 22
OUR COMMITMENT We are committed to support our distributers with: Training for client physicians Physician exchange and case consultations Training for sales force Support with launching events Scientific workshops and hands on training Marketing tools and materials Hosting at our booths in worldwide conferences 23
INTERNATIONAL ENDOVASCULAR EXCHANGE NETWORK 24
IEEN International Endovascular Exchange Network ENDOCOR s sister company, IEEN (International Endovascular Exchange Network) is pioneering medical services through education, training and evidencebased research. IEEN is a platform for endovascular scientific knowledge sharing and collaboration which includes the following services: 25
TRAINING & EDUCATION IEEN@Germany Through IEEN@Germany, international senior doctors have the chance to come to Germany to further develop and expand their knowledge in endovascular medicine, and to participate in a number of workshops and handson treatment training sessions with IEEN partner excellence centers throughout Germany. This allows international physicians to keep up-to-date with the latest developments in endovascular medicine and be at the forefront of endovascular research and innovation. 26
INTERNATIONAL ENDOVASCULAR EXCHANGE NETWORK 27
CUTTING EDGE TREATMENTS IEEN@HostCountry Through IEEN@HostCountry, German doctors at the level of Professor or Head of Department would be mobilized to perform endovascular interventions in host countries across the world, sharing the application of advanced new techniques in endovascular medicine and showcasing ENDOCOR's products. This will allow host country physicians to learn from German know-how and apply the knowledge from the forefront of medical science to their patients. 28
Manufacturer: ENDOCOR GmbH Esplanade 41 20354 Hamburg Germany T +49 40 819 89 186 F + 49 40 572 47 570 www.endocor.com 29