The influence of societal individualism on a century of tobacco use: modelling the prevalence of smoking Appendices A and B

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The influence of societal individualism on a century of tobacco use: modelling the prevalence of smoking Appendices A and B J.C. Lang, D.M. Abrams, and H. De Sterck A Additional Tables and Figures Table A.1: Summary of data on smoking prevalence x and cigarette consumption c. Cigarette consumption per person Smoking prevalence (x) per day (c) No. Country Abbrev. Obs. Period No. of Obs. Obs. Period No. of Obs. Source 1 Australia AUS 1964 21 16 192 21 91 [4] 2 Austria AUT 1972 26 5 1923 24 82 [4] 3 Belgium BEL 1997 28 4 1921 211 91 [4] 4 Canada CAN 1964 211 29 192 21 91 [4] 5 Denmark DNK 197 21 41 192 21 91 [4] 6 Finland FIN 1978 211 34 192 29 9 [4] 7 France FRA 196 21 22 19 21 93 [4] 8 Greece GRE 1998 29 6 192 1995 76 [41] 9 Hungary HUN 1994 29 4 192 212 87 [4] 1 Iceland ICE 1987 212 26 1932 1995 64 [41] 11 Ireland IRE 1973 27 14 192 1995 76 [41] 12 Israel ISR 1996 21 8 1967 1995 29 [41] 13 Italy ITA 198 212 23 195 21 73 [4] 14 Japan JPN 1965 211 47 192 27 88 [4] 15 Netherlands NLD 1966 211 39 1923 1995 67 [41] 16 New Zealand NZL 1976 212 28 192 29 9 [4] 17 Norway NOR 1973 212 4 1927 211 85 [4] 18 Poland POL 1996 29 4 1925 1995 43 [41] 19 Portugal PRT 1987 26 4 194 1995 56 [41] 2 Romania ROM 192 1995 52 [41] 21 Spain SPA 1985 211 11 192 21 87 [4] 22 Sweden SWE 198 211 32 192 26 87 [4] 23 Switzerland CHE 1992 27 4 1934 29 76 [4] 24 United Kingdom GBR 196 21 38 195 29 15 [4] 25 United States USA 1965 211 36 192 21 91 [4] A.1

Table A.2: Result from Eq. (3) regression of smoking prevalence x on cigarette consumption c. Country Ĉ 1 2 B 1 2 R 2 p n obs Australia 4.5 ± 1.3.3 ± 8.8.8 3.2 1 6 16 Austria. ± 4.9 24.2 ± 32.4..99 4 Belgium 2.6 ± 2.3 13. ± 81.5.13.64 4 Canada 3.5 ±.5 6.3 ± 3.8.87 3. 1 13 28 Denmark. ± 9.2 4.5 ± 44.4..99 41 Finland 2. ±.7 15.8 ± 2.8.55 1. 1 6 32 France 1.8 ±.5 19.1 ± 2.5.72 6.3 1 7 22 Greece Hungary 1.9 ± 1.6 17.4 ± 11.2.93 3.5 1 2 4 Iceland 4.9 ± 1.2.9 ± 7..93 2.6 1 5 9 Ireland 5.4 ± 1.1 4. ± 7.4.93 1.7 1 6 11 Israel Italy 4.8 ± 2.5.3 ± 13.2.47 6.1 1 4 21 Japan 1.3 ± 3.2 25.7 ± 27.2.2.43 43 Netherlands 4.8 ± 3.2 2.5 ± 15..32 4.7 1 3 23 New Zealand 2. ±.3 18.8 ± 1.4.86 2.6 1 12 27 Norway 7.2 ± 4.3 5.1 ± 1.6.24 1.6 1 3 39 Poland Portugal 1 Romania Spain 6. ± 6.2 7.4 ± 41.7.38 5.7 1 2 1 Sweden 5.4 ±.6 4.3 ± 2.3.92 1.7 1 15 27 Switzerland 2.8 ± 5.6 7.2 ± 38.6.69.17 4 United Kingdom 5.6 ±.7 1.6 ± 4.5.88 5.3 1 18 37 United States 3.6 ±.3.1 ± 2.3.95 1.1 1 22 35 ± indicates 95% confidence intervals. We report R 2 values for the linear regression of x on c, the p-value of the correlation between x and c, and the number of s for which both x and c measurements are available, n obs. A.2

Table A.3: Hofstede s Individualism Index IDV and peak in cigarette consumption (t max ) Country IDV Peak (t max ) Australia 9 1974 Austria 55 1979 Belgium 75 1973 Canada 8 1976 Denmark 74 1976 Finland 63 1963 France 71 1985 Greece 35 1986 Hungary 8 198 Iceland 6 1984 Ireland 7 1974 Israel 54 1974 Italy 76 1984 Japan 46 1977 Netherlands 8 1977 New Zealand 79 1975 Norway 69 24 Poland 6 1991 Portugal 27 1994 Romania 3 1995 Spain 51 1985 Sweden 71 1976 Switzerland 68 1972 United Kingdom 89 1973 United States 91 1963 A.3

(a) Australia.54.27 192 1945 197 1995 22 12 6 (b) Canada.54.27-2 192 1945 197 1995 22 14 6 (c) France.54.27 19 1925 195 1975 22 2 4.5-11 (d) New Zealand.54 18.27 4-1 192 1945 197 1995 22.54 (e) Sweden 9.27 4-1 192 1945 197 1995 22.54 (f) United Kingdom.27 19 1925 195 1975 22 1 5.54.27 (g) United States 192 1945 197 1995 22 Figure A.1: Raw smoking prevalence and cigarette consumption data. Raw smoking prevalence x (blue asterisks, left axis) and raw cigarette consumption c (black dots, right axis) versus time. Raw cigarette consumption data is given in grams per person per day. A single outlier for smoking prevalence (x) for the country of France (panel c) is denoted with a red asterisk. 15 7.5 A.4

(a) Australia.54.27 192 1945 197 1995 22 (c) France.54.27 192 1945 197 1995 22.54 (e) Sweden.27 192 1945 197 1995 22 (b) Canada.54.27 192 1945 197 1995 22 (d) New Zealand.54.27 192 1945 197 1995 22.54 (f) United Kingdom.27 192 1945 197 1995 22.54.27 (g) United States 192 1945 197 1995 22 Figure A.2: The result of fitting Eq. (1) to the estimated smoking prevalence ˆx. Estimated smoking prevalence values ˆx are given by blue dots. A.5

Trillions of cig. smoked per B Additional Remarks on Model Implications and Study Design B.1 A Counterfactual Scenario In this section we illustrate the effect size of individualism/collectivism on the dynamics of the smoking epidemic by considering a simple counterfactual scenario. Specifically, holding all other fitted parameters constant, we consider how the smoking epidemic in the United States might have evolved if the United States (IDV=91 and a =.963) were about 2% less individualistic (IDV=89 and, using the slope from Fig. 4(a), a =.974). Fig. A.3 plots an estimate for the number of cigarettes smoked per (in trillions) versus time. Integrating the difference between the number of cigarettes smoked per versus time for the United States with fitted (a =.963, solid line) and counterfactual (a =.974, dashed line) relative conformity implies that, according to our model, if the United States had 2% lower individualism during the 9 period from 192 21 then there would have been approximately 7 1 12 fewer cigarettes smoked. This is equivalent to a 16% decrease in the number of cigarettes smoked. 8 6 4 2 192 1935 195 1965 198 1995 21 Year Figure A.3: Solution to Eq. (1) for the United States with a =.963 (solid) and a =.974 (dashed). Parameters x, b, u, u, and δ are as reported for the United States in Table 1. The number of cigarettes smoked per is estimated as follows. First, we observe that for t the number of cigarettes smoked per smoker per day is 1 C d (t) = c(t)/x(t). Therefore, using Eq. (4) we find that the number of cigarettes smoked per smoker per C a (t) = 365 C d (t) can be bounded. For example, in the case of the United states, where ˆB <, we find that C a (t) is bounded by 1.2 1 4 = 365 Ĉ 1 C a (t) = 1 ˆB/ˆx(t) Ĉ 1 ˆB/ min ˆx(t) Ĉ = 1.4 1 4. Since the lower and upper bounds are relatively tight, we estimate the number of cigarettes smoked per smoker per to be the average of the lower and upper bounds C a 2 ˆB/ min ˆx(t) 2Ĉ 1 Assuming 1.2 cigarettes per gram, as in [39,4]. 1. 1 4. B.1

We cross-check this estimate with the direct estimate of C a taken by averaging c(t)/x(t) for all times where both measurements are available in the raw data (data shown in Fig. A.1). These two estimates agree to two significant figures. Finally, we estimate the number of cigarettes smoked per to be ˆx(t) N pop (t) C a, where N pop (t) is the total population at time t. The total population for the United States is taken from US census estimates [47,48] and is given CSV format in the additional file, Additional File 4.csv, which contains two columns: (t) and population N pop (t). We emphasize that in the counterfactual scenario described above we have only changed a for the United States while keeping all other fitted parameters constant, merely to illustrate that the effect of small changes in a in the model can be large. Therefore, the broad variation in the fitted a across countries, as illustrated in Fig. 4(a), can indeed be expected to lead to a large effect size on cigarette consumption. Note, however, that the results from this counterfactual scenario do not imply that less individualism automatically means lower cigarette consumption, since countries with lower IDV (higher a) than the United States also tend to differ for other fitted parameters and quantities in the model, resulting in substantially different solutions to Eq. (1). B.2 Order of Model Development and Additional Analyses The mathematical model was proposed and developed before the data sets were compiled. Following the specification of the model no modifications were made or required to produce the reported results. The correlation between a and IDV was investigated after fitting the model to the data, and strong negative correlation was obtained as a confirmation of the mechanism proposed in the model. In a subsequent step, to further corroborate the hypothesis that societal individualism influences the temporal dynamics of smoking prevalence at the population level, the correlation between IDV and t max was also confirmed for the raw smoking data, independent of the mathematical model. No analysis was performed with additional variables. However, the sensitivity of the model to several assumptions was tested. For example, and as already mentioned, one alternative to the discounting function presented in Eq. (2) was tested: we assumed a step-function individual utility function that took value u for t t and u for t > t. We also tested the model for various combinations of local and global parameters with both utility functions. For example, whereas in our model δ and b were taken to be global parameters and x i,, u i,, u i,, and a i were taken to be local parameters, we also tested the cases where (a) b was the only global parameter and x i,, u i,, u i,, a i, and δ i were taken to be local parameters, (b) a and b were taken to be global parameters and x i,, u i,, u i,, and δ i were taken to be local parameters, and (c) a, b, and δ were taken to be global parameters and x i,, u i,, and u i, were taken to be local parameters. These variations confirmed that our modelling procedure was robust, i.e. these variations all produced qualitatively similar results. B.2