Tables of Normal Values (As of February 2005)

Tables of Normal Values (As of February 2005) Note: Values and units of measurement listed in these Tables are derived from several resources. Substantial variation exists in the ranges quoted as normal in various references and at different laboratories. Therefore, the values in these Tables are meant to be representative only. Table 1: Vital Signs and Body Mass Index Parameter Normal Values Blood Pressure (Systolic / Diastolic) Optimal < 120 / 80 mmhg Normal < 130 / 85 High-Normal 130 / 85 to 139 / 89 Hypertension, stage 1 140 / 90 to 159 / 99 Hypertension, stage 2 160 / 100 to 179 / 109 Hypertension, stage 3 180 / 110 Heart Rate (HR) or Pulse Bradycardia < 60 beats per minute Normal 60 100 Tachycardia > 100 Respiration Rate (RR) Bradypnea < 12 breaths per minute Normal 12 16 Tachypnea > 16 Body Temperature Fever Low-grade 37.2 38.0 C Moderate 38.1 40.0 C High > 40.0 C Normal 37 C (approximately) Hypothermia < 35.0 C Body Mass Index (BMI) Underweight < 18.5 kg/m 2 Normal 18.5 24.9 Overweight 25.0 29.9 Obesity class I 30.0 34.9 Obesity class II 35.0 39.9 Obesity class III (extreme, morbid) > 40.0 Council for Continuing Pharmaceutical Education Normal Values Page 1

Table 2: Common Blood Chemistries Albumin 31 43 g/l 3.1 4.3 g/dl Alanine Aminotransferase (ALT) Female 7 30 U/L 7 30 U/L Male 10 55 10 55 Alkaline phosphatase (ALP) Female 30 100 U/L 30 100 U/L Male 45 115 45-115 Ammonia NH 3 12 48 µmol/l 12 48 µg/dl Amylase 53 123 U/L 53 123 U/L Aspartate Aminotransferase (AST) 9 25 U/L 9-25 U/L Bicarbonate (HCO 3 ) (also CO 2 content) 22 26 mmol/l 22 26 meq/l Bilirubin, total 0 17 µmol/l 0 1.0 mg/dl Bilirubin, conjugated (direct) 0 7 µmol/l 0 0.4 mg/dl Blood Urea Nitrogen (BUN) 3.0 6.5 mmol/l 8 18 mg/dl Calcium 2.1 2.6 mmol/l 8.5 10.5 mg/dl Calcium, ionized 1.14 1.3 mmol/l 1.14 1.3 mmol/l Carbon dioxide content 24 30 mmol/l 24 30 mmol/l Carbon dioxide pressure, arterial (PaCO 2 ) 4.7 6.0 kpa 35 45 mmhg Chloride 100 108 mmol/l 100 108 mmol/l Cholesterol, total Desirable < 5.2 mmol/l < 200 mg/dl Borderline high 5.2 6.2 201 240 High > 6.2 > 241 Cholesterol, LDL Optimal < 2.6 mmol/l < 100 mg/dl Near optimal 2.6 3.35 100 130 Borderline high 3.36 4.13 131 160 High 4.14 4.91 161 190 Very high > 4.91 > 190 Cholesterol, HDL Low < 1.00 < 40 mg/dl Creatine Kinase (CK) (also CPK) Female 40 150 U/L 40 150 U/L Male 60 400 60 400 Normal Values Page 2 Council for Continuing Pharmaceutical Education

Table 2: Common Blood Chemistries cont d Creatine Kinase isoenzymes, MB Fraction (Myocardial Infarction) 0 5 µg/l 0 5 ng/l Copper 11.0 22.0 µmol/l 70 140 µg/dl Creatinine, serum 53 133 µmol/l 0.6 1.5 mg/dl Creatinine Clearance 1.24 2.08 ml/sec 75 125 ml/min Ferritin Female 10 200 µ/l 10 200 ng/ml Male 30 300 30 300 Folic Acid (Folate) 4 22 nmol/l 2 10 ng/ml Gamma Glutamyl Transferase (GGT) Female 1 70 U/L 1 70 U/L Male 1 94 1 94 Glucose, fasting Normal 4.0 6.0 mmol/l 70 110 mg/dl Glucose, postprandial Normal 4.4 7.7 mmol/l 80 125 mg/dl Glycosylated Hemoglobin HbA1C Normal 0.04 0.06 4 6% β-hydroxybutyrate < 100 µmol/l < 1.0 mg/dl Iron Female 11 29 µmol/l 60 160 µg/dl Male 14 32 80 180 Iron-Binding Capacity, total TIBC 45 82 µmol/l 250 460 µg/dl Lactic Acid (Lactate) 0.5 2.2 mmol/l 5 22 mg/dl Lactate Dehydrogenase (LDH) 110 210 U/L 110 210 IU/L Magnesium 0.7 1.0 mmol/l 1.4 2.0 meq/l Nitrogen (as Amino Acids) 2.9 4.3 mmol/l 4.0 6.0 mg/dl Osmolality Serum 280 296 mmol/kg 280 296 mosm/kg Urine 50 1200 mmol/l 50 1200 mosm/kg Oxygen partial pressure, arterial PaO 2 10.0 13.3 kpa 75 100 mm Hg ph Acidity 7.35 7.45 ph units 7.35 7.45 ph units Phosphate (as Phosphorus, inorganic) 0.80 1.60 mmol/l 2.5 5.0 mg/dl Council for Continuing Pharmaceutical Education Normal Values Page 3

Table 2: Common Blood Chemistries cont d Potassium 3.5 5.0 mmol/l 3.5 5.0 meq/l Protein, total Plasma 60 80 g/l 6.0 8.0 g/dl Urine < 0.15 g/day < 150 mg/24 hr PSA Prostate Specific Antigen Male, < 40 years 0 2 0 2 Male, 40 years or older 0 4 0 4 Pyruvate (Pyruvic Acid) 35 100 µmol/l 0.30 0.90 mg/dl Sodium 135 145 mmol/l 135 145 meq/l Transferrin 1.91 3.65 g/l 191 365 mg/dl Transferrin Saturation 0.2 0.5 20 50% Triglycerides (fasting) Normal < 1.70 mmol/l < 150 mg/dl Borderline high 1.70 2.25 150 200 High 2.26 5.64 201 500 Very high > 5.64 > 500 Uric Acid (Urate) Female 137 393 µmol/l 2.3 6.6 mg/dl Male 214 506 3.6 8.5 Urea Nitrogen, Blood (BUN) 2.9 8.9 mmol/l 8 25 mg/dl Vitamin B 12 (Cyanocobalamin) Normal < 184 pmol/l < 250 pg/ml Deficient < 92 < 125 Zinc 11.5 18.5 µmol/l 75 120 µg/dl Normal Values Page 4 Council for Continuing Pharmaceutical Education

Table 3: Hematological Parameters Red Blood Cells Erythrocytes (RBC) Female 3.5 5.0 X 10 12 /L 3.5 5.0 X 10 6 /mm 3 Male 4.3 5.9 X 10 12 /L 4.3 5.9 X 10 6 /mm 3 Reticulocyte Count (% red blood cells) 0.005 0.025 0.5 2.5% Hematocrit Female 0.33 0.43 33-43% Male 0.39 0.49 39-49% Hemoglobin Female 115 155 g/l 11.5 15.5 g/dl Male 140 180 g/l 14.0 18.0 g/dl Erythrocyte Sedimentation Rate (ESR) Female 1 25 mm/h 1 25 mm/h Male 0 17 0 17 White Blood Cells (WBC) White Blood Cell Count 4.5 11.0 X 10 9 /L 4.5 11.0 X 10 3 /mm 3 White Blood Cell Differential Neutrophils 0.54 0.62 45 75% Lymphocytes 0.25 0.33 16 46% Monocytes 0.03 0.07 4 11% Bands 0.03 0.05 0 5% Eosinophils 0.01 0.03 0 8% Basophils 0 0.0075 0 3% Coagulation Anti-Xa assay Low Molecular Weight Heparin activity 0.5 1.0 ku/l 0.5 1.0 U/mL Bleeding Time 2.0 9.5 min 2.0 9.5 min Coagulation Time 6 17 min 6 17 min Fibrinogen 1.75 4.0 µmol/l 175 400 mg/dl International Normalized Ratio (INR) Normal 0.8 1.2 0.8 1.2 Therapeutic (anticoagulated) 2.0 3.0 2.0 3.0 Plasminogen 0.84 1.40 84 140% Platelet Count (Thrombocytes) 150 350 X 10 9 /L 150 350 X 10 3 /mm 3 Prothrombin Time (PT) 11.2 13.2 sec 11.2 13.2 sec Partial Thromboplastin Time (PTT) 22 34 sec 22 34 sec Thrombin Time 16 24 sec 16 24 sec Council for Continuing Pharmaceutical Education Normal Values Page 5

Table 4: Hormones Adrenocorticotropin (ACTH) 1.3 16.7 pmol/l 6.0 76.0 pg/ml Aldosterone (Normal Sodium Diet) 55 250 pmol/l 2 9 ng/dl Calcitonin Female 2 17 ng/l 2 17 pg/ml Male 3 26 3 26 Cortisol Time: 0800 1200 h 138 690 nmol/l 5 25 µg/dl 1200 2000 h 138 414 5 15 2000 0800 h 55 193 0 10 Estrogens (as Estradiol) Female (premenopausal) 185 1625 pmol/l 50 450 pg/ml Male < 184 < 50 Follicle-Stimulating Hormone (FSH) Female (premenopausal) 1 26 U/L 1 26 mu/ml Male 1 12 1 12 Glucagon 20 100 ng/l 20 100 pg/ml Growth Hormone 2 5 µg/l 2 5 ng/ml Insulin 14.35 143.5 pmol/l 2 20 µu/l Luteinizing Hormone (LH) Female (premenopausal) 0.6 105 U/L 0.6 105 U/L Male 2 12 2 12 Parathyroid Hormone (PTH) 10 60 ng/l 10 60 pg/ml Progesterone Female (mid-luteal phase) 9.5 64 nmol/l 3 20 ng/ml Male < 3.18 nmol/l < 1.0 ng/ml Prolactin < 20 µg/l < 20 ng/ml Renin Activity Normal Sodium Diet 0.08 0.83 ng/l/sec 0.3 3.0 ng/ml/hr Thyroxine (T4) 58 140 nmol/l 4.5 10.9 µg/dl Triiodothyronine (T3) 0.9 2.78 nmol/l 60 181 ng/dl Testosterone Female 0.21 2.98 nmol/l 6 86 ng/dl Male 9.36 37.1 270 1070 Thyroid-Stimulating Hormone (TSH) 0.5 5.0 µu/ml 0.5 5.0 µu/ml Vitamin D3 - Cholecalciferol 60 105 nmol/l 24 40 ng/ml 25-Hydroxy-Cholecalciferol 20 105 nmol/l 8 42 ng/ml 1,25-Dihydroxy-Cholecalciferol 43 148 pmol/l 18 62 pg/ml Normal Values Page 6 Council for Continuing Pharmaceutical Education