Extremity Trauma 2016 Principles

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SNERC 2016 Extremity Trauma 2016 Principles Roman Hayda, MD, COL (ret) Associate Professor Brown University Director Orthopaedic Trauma Rhode Island Hospital

Disclosure Speaker Bureau Synthes Smith and Nephew AONA Consultant Biointraface (unpaid) Committees METRC executive OTA military OTA classification OTA disaster preparedness

Objectives Injury patterns and demographics Principles of fracture care Rehabilitation implications What can we do better

Perfect surgery + Unmotivated patient or Poor rehabilitation = Bad result

Imperfect surgery + Motivated patient or Excellent rehabilitation = Good result

Statistics Life years lost Trauma Cancer Heart dz other CDC 2014

Cost $671 billion/yr CDC 2015

Falls ER visits: 2.5 X 10 6 Hospitalizations: 700,000 Hip fxs: 250,000 CDC 2015

Disability 1 in 4 20 yr olds disabled before retirement* 12% Americans disabled, half are working age* 8.8 million Americans receive SSDI* MSK disorder: 28.5% of disabled** * Social Security Administration 2013 ** Council on Disability Awareness 2009

Mortality vs Disability Global Burden of Disease, World Bank, 2010

Disability/Age

Disability by Country

Injury Patterns Monotrauma: single injury Multitrauma: multiple injuries to single system Polytrauma: injuries to multiple systems

Injury Mechanism Low energy Falls Sports High energy Motor vehicle Industrial Ballistic Falls from height

Fracture Distribution frequency energy age

Evolution of Orthopaedic Surgery

Evolution of Fracture care Pre-surgical era: casts, slings, and traction Early surgical era: fixation of some problem fractures 1980 s: Fixation of fractures to save lives and reduce morbidity Early Total Care 1990 s-2000 s: Damage control surgery Now: Early Appropriate Care

Early Appropriate Care JOT 2011 750 pts with femur fx mean ISS 23.7 Fix w nail only 9 exfix Early resuscitation (ph, base deficit, lactate, ICP) Complications: Early 18.9% v late 42.9% LOS, ICU, vent days abd inj more complic than severe head injury Chest inj assoc with pulm complic

JOT 2013 Correct ph > 7.25 by 8 hrs; tx of femur, pelvis and acetabulum in 24 hrs complications JT 2014 EAC vs Clinical Grading scale (Pape) no difference in complications

Treatment options Cast/bracing Plate and screws Rod or nail External fixator Simple unilateral circular

Fracture anatomy Not all are the same Bone zones Diaphysis Metaphysis Articular surface

External support Temporary Definitive Casts and Braces Wrist and ankle humerus Nonsurgical candidates Age compliance Many pediatric fractures UE LE

Humeral Fracture Cuff Figure from Rockwood and Green, 4th

Caveats Loss of reduction Pressure sores Compartment syndrome Stiffness/atrophy

Plates and Screws Direct control of fragments Excellent for articular fractures May be a reduction tool May require more exposure Anatomic limitations May be minimally invasive Limited inherent stability Advances Locking screw

Common uses Fractures around joints Diaphyseal fractures Most upper extremity Select lower extremity Deformity precluding IM nail

Elbow Fracture with bone loss 52 yo MVC, Open distal humerus Open segmental femoral shaft with bone loss

Staged reconstruction with iliac crest bone graft Iliac crest graft

healed with ROM of 10-135 Returned to wt lifting and home improvement

Example of bridge plating in a highly comminuted osteoporotic distal radius fracture 33

Not perfect

Rods or Nails Fit inside medullary canal Interlocking screws provide axial and rotational stability Minimal dissection Preserves blood supply Mechanically closer to center of force

Biomechanics Shorter Moment Arm

Rods and Nails Preferred for diaphyseal fractures Tibia and femur Rarely for humerus Tumor Long segment of comminution Newer techniques have extended indications to the metaphysis

Reduction maneuvers Length Rotation Angulation 39

Can also fail

External Fixation Pins or wires into bone External clamps and bars provide support Temporary Unilateral frame Definitive Circular frame

Unilateral Frame

Circular External Fixation

Beltran, et al, Composite Bone and Soft Tissue Loss Treated With Distraction Histiogenesis, J Surgical Advances, 2010

Therapy implications Life is motion; motion is life Articular cartilage nutrition Ligament and tendon healing Orientation of collagen with controlled stress Muscle activity prevents contracture and atrophy Bone healing responds to load

To weight bear or Not to weight bear YES Diaphyseal femur and tibia fx tx with rod Humerus shaft fx plate or rod Geriatric hip fractures Circular frames Articular fx NO Metaphyseal fx Segmental defects Compromised fixation Osteoporosis Neuropathy/noncompliant pt

Motion restrictions Articular fractures Tibial plateau fracture: posterior joint is loaded in flexion Ligament injury Elbow Tendon injury Patellar and quad tendon Rotator cuff

Amputation Traumatic Severe trauma Vascular injury Bone loss Loss of skin/muscle Major nerve disruption Unreconstructible Risk to patient Poor long term function

Amputation vs. Salvage Multidisciplinary decision Based on an overall assessment of all the tissues of the limb: Muscle Bone Vessels Nerves

Advances in reconstruction Wound management Bead pouch Negative pressure dressing Bone stabilization Locking plates Circular frames Minimally invasive techniques Bone regeneration Distraction osteogenesis RIA bone graft BMP Microvascular reconstruction Free flap coverage Composite tissue reconstruction Limb replant Limb allotransplantation

Advances in Amputation Wound management Negative pressure dressing Free Tissue transfer to preserve joint Gel liners for improved socket fit Energy storing terminal devices Myoeletric prosthesis Microprocessor controlled knee (C- Leg) Targeted reinnervation

Societal Factors

LEAP Study Bosse et.al. 2001-2006 Prospective observational study - 569 patients 2 and 7 year follow up Less complications in amputations Less hospitalizations in amputations Functional outcomes equal at two years but early cost $ much more money and time with added loss of social, family and work life with salvage group Outcome dependent on self efficacy, education, race, insurance

Military Extremity Trauma Amputation and Limb Salvage Study Multicenter retrospective study of severely injured limbs treated with salvage or amputation Lower AND Upper extremity The METALS Study group. METALS: Limb Salvage vs amputation of the lower extremity combat injury outcomes. JBJS-A. 2013

Mean SMFA Dysfunction Score (Higher Score = Worse Outcome) POP N NORM Significantly different from unilateral salvage (p < 0.05) after adjusting for covariates

Upper Extremity Results 70 60 50 40 30 20 Salvage amputation 10 0 SMFA depressive symptoms (%) PTSD (%) pain score

14 yo m run over by bus Ankle fx dislocation Skin loss from knee to ankle Loss of entire anterior and lateral muscle compartment

IDEO Intrepid Dynamic Exoskeleton Orthosis

JBJS, 2012

Slower cadence, shorter stance Kinetic and efficiency data equivalent JOT, 2016

41/50 preferred retained limb No difference < or > 2yrs post injury CORR 2014

Post-traumatic arthritis Not just related to reduction of fracture Cellular apoptosis Pilon fx vs plateau Upper vs Lower extremity BJJ, 2007

38 yo tourist Fell jumping on beach rocks Open pilon (ankle) fx

Other Factors Pain PTSD Depression

Pain Multiple factors Genetics Societal Psychologic Management Expectation of control not elimination Early effective tx affects long term outcome

Pharmacologic Opiates Pain Management Long acting Contracts NSAID Short term use does not affect bone healing Ketorolac Acetominophen Gabapentinoids Tricyclics Other

Other management Blocks Single shot Continuous Counseling Patient engagement Return sense of control Consistent message among providers

Preinjury narcotic prescription 15.5% (9.5%) Multiple prescriptions 12.2% (6.4%) Multiple pre injury: 6 X >12 wks Opiates multiple providers: 3.5 X JBJS, 2013

PTSD Prevalence up to 50% trauma victims War veterans 36% w TBI; 16% w/o TBI 18% amputee and limb salvage Predictor: wishful thinking Treatment: Behavioral therapy Pharmacologic: SSRI, α-blocker

Depression Prevalence: up to 45% moderate; 3.7% severe LEAP:19% severe Treatment Recognition Pharmacologic Psychotherapy Electroconvulsive therapy

Imperfect surgery + Motivated patient or Excellent rehabilitation = Good result

83 yo Fell Bilat elbow fx left right left right left

3 months later right left right left

Traumatic hemipelvectomy Knee dislocation Open tibia Arrested 3 times in first day

Thank You