The Medical Letter publications are protected by US and international copyright laws. Forwarding, copying or any other distribution of this material is strictly prohibited. For further information call: 800-211-2769 Last updated: April 27, 2017 Comparison Table: Some Topical Corticosteroids The Medical Letter on Drugs and Therapeutics Comparison Table: Some Topical Corticosteroids 1,2 Super-High Potency Betamethasone dipropionate augmented generic Apply once/d or bid Should only be used short-term $105.70 (15 g x 2) Diprolene (Merck) Clobetasol propionate generic Clobex (Galderma) gel foam spray shampoo Apply once/d Should not be used under occlusion Ointments are generally the most effective formulations Foams and sprays can be applied to large areas, but the alcohol base used in many of them may cause burning Foam: dispense small amount onto a saucer or other cool surface; will melt immediately if dispensed onto hands 170.70 (15 g x 2) 124.50 (30 g) 158.40 (30 g) 222.35 (30 g) 136.50 (50 ml) 149.00 (60 ml) 292.30 (50 g) 329.10 (59 ml) 303.60 (118 ml) 500.10 (60 ml) spray 442.50 (59 ml) shampoo Apply once/d 837.80 (118mL) Olux (Prestium/Mylan) foam 493.00 (50 g) Olux-E (Mylan) foam 493.00 (50 g) Temovate (Fougera) 264.10 (30 g) 267.50 (30 g) Cormax (Hi Tech) 36.00 (50 ml) Fluocinonide generic 0.1% Apply once/d 323.80 (30 g) Vanos (Valeant) 952.30 (30 g) Halobetasol propionate generic Apply once/d or bid 153.10 (50 g) 178.10 (50 g) Ultravate (Ranbaxy) 916.00 (50 g) 916.00 (50 g) 916.00 (60 ml) e91
High Potency Amcinonide generic 0.1% or tid Should only be used short-term Betamethasone dipropionate augmented Apply once/d or bid generic $324.00 (60 g) 42.50 (15 g x 2) Diprolene AF (Merck) Betamethasone dipropionate generic Desoximetasone generic Topicort (Taro) 0.25% Apply once/d or bid 170.70 (15 g x 2) 87.00 (45 g) 199.20 (60 g) 214.50 (60 g) 343.80 (60 g) 343.60 (60 g) Desoximetasone generic gel 147.00 (15 g x 2) Diflorasone diacetate generic Apply 1-3 times/d 335.50 (30 g) Fluocinonide generic Apply 2-4 times/d 111.20 (30 g) gel 95.30 (30 g) 72.90 (30 g) 81.00 (60 ml) Halcinonide Halog (Ranbaxy) 0.1% -tid 452.80 (30 g) 452.80 (30 g) Mometasone furoate generic 0.1% Apply once/d 32.00 (15 g x 2) Elocon (MSD) 109.50 (15 g x 2) Medium-High Potency Amcinonide generic 0.1% or tid 189.00 (30 g) Betamethasone dipropionate generic Betamethasone valerate generic Desoximetasone generic 0.1% Apply once/d or bid Apply 1-3 times/d 271.40 (60 ml) 84.50 (15 g x 2) 32.50 (15 g x 2) 35.40 (15 g x 2) 87.40 (15 g x 2) Diflorasone diacetate generic Apply 1-3 times/d 335.50 (30 g) Fluocinonide emollient generic Apply 2-4 times/d 77.10 (30 g) Fluticasone propionate generic 0.005% 57.20 (30 g) Triamcinolone acetonide generic 0.5% Apply 2-4 times/d 16.40 (15 g x 2) or tid 17.39 (15 g x 2) e92
Medium Potency Betamethasone dipropionate spray Sernivo: shake well before use Sernivo (Promius) Luxiq: dispense small amount onto a saucer or other cool surface; foam $780.00 (120 ml) Betamethasone valerate generic 0.12% foam will melt immediately if dispensed onto hands 261.50 (50 g) Luxiq (Prestium/Mylan) 411.60 (50 g) Fluocinolone acetonide generic 0.025% Apply 3-4 times/d 57.10 (15 g x 2) Synalar (Medimetriks) Apply 2-4 times/d 409.25 (120 g) Flurandrenolide generic or tid 523.00 (60 g) Cordran (Aqua) 581.00 (60 g) Hydrocortisone valerate generic 0.2% or tid 157.40 (15 g x 2 ) Mometasone furoate generic 0.1% Apply once/d 35.00 (15 g x 2) Elocon (MSD) 109.50 (15 g x 2) Triamcinolone acetonide generic 0.1% or tid 6.00 (30 g) 6.20 (30 g) Triderm (Crown) 355.00 (30 g) Triamcinolone acetonide Trianex (Promius) Apply 2-4 times/d 860.00 (430 g) Medium-Low Potency Betamethasone dipropionate generic 38.50 (60 ml) Betamethasone valerate generic 0.1% Apply 1-3 times/d 35.50 (15 g x 2) Desonide generic Apply 2-4 times/d 96.20 (15 g x 2) Fluocinolone acetonide generic 0.025% Apply 2-4 times/d 58.50 (15 g x 2) Synalar (Medimetriks) 409.30 (120 g) Flurandrenolide generic or tid 825.30 (120 g) 825.30 (120 ml) Cordran (Aqua) 962.00 (120 g) 962.00 (120 ml) Fluticasone propionate generic Apply once/d or bid 25.80 (30 g) Apply once/d 665.70 (120 ml) Cutivate (PharmaDerm) Apply once/d or bid 113.10 (30 g) Apply once/d 1068.80 (120 ml) e93
Medium-Low Potency (continued) Hydrocortisone butyrate generic 0.1% or tid $100.20 (15 g x 2) 95.50 (15 g x 2) 191.20 (60 ml) Locoid (Onset) 218.50 (15 g x 2) 206.30 (15 g x 2) 416.50 (60 ml) Locoid Lipo 150.10 (15 g x 2) Hydrocortisone probutate Pandel (Sandoz) 0.1% Apply once/d or bid 984.10 (80 g) Hydrocortisone valerate generic 0.2% or tid 143.30 (15 g x 2) Prednicarbate generic 0.1% 114.30 (60 g) 61.50 (60 g) Dermatop (Valeant) 133.40 (60 g) 110.50 (60 g) Triamcinolone acetonide generic 0.025% Apply 2-4 times/d 10.00 (15 g x 2) Triamcinolone acetonide generic 0.1% Apply 3-4 times/d 29.00 (60 ml) Low Potency Alclometasone dipropionate generic -tid 90.50 (60 g) 73.90 (60 g) Betamethasone valerate generic 0.1% Verdeso should be dispensed by inverting can; upright actuation may cause incorrect dosage delivery 60.00 (60 ml) Clocortolone pivalate generic 0.1% Apply tid 268.70 (45 g) Cloderm (Promius) 325.50 (45 g) Desonide generic 128.50 (30 g) 236.90 (60 ml) Desowen (Galderma) 516.70 (60 g) 334.40 (60 ml) Desonate (Bayer) gel 513.40 (60 g) Verdeso (Stiefel) foam 780.00 (100 g) Fluocinolone acetonide generic 0.01% Apply 2-4 times/d 111.40 (60 g) 125.30 (60 ml) Triamcinolone acetonide generic 0.025% Apply 2-4 times/d 7.20 (30 g) 29.00 (60 ml) e94
Lowest Potency Hydrocortisone generic Hydrocortisone generic 2.5% 1.0% -qid Apply up to tid-qid Hydrocortisone 2.5% is available by prescription only Hydrocortisone 1% and 0.5% are available without a prescription Individual retailers may have their own OTC generic products May be ineffective for some indications $2.70 (20 g) 3.00 (30 g) 16.40 (60 ml) 6.80 (30 g) 4 Safe for use on the face and intertriginous areas 6.80 (30 g) 4 Aquanil-HC (Person & Covey) 8.00 (120 ml) 4 Hydrocortisone generic 0.5% Apply up to tid-qid 3.30 (30 g) 5.00 (30 g) 4 Nu-Derm Tolereen (Obagi) 0.5% 27.00 (57 g) 1. Drugs for psoriasis. Med Lett Drugs Ther 2015; 57:81. 2. Drugs for allergic disorders. Med Lett Drugs Ther 2017; 59:71. 3. Approximate WAC for smallest available package size. WAC = wholesaler acquisition cost or manufacturer s published price to wholesalers; WAC represents a published catalogue or list price and may not represent an actual transactional price. Source: AnalySource Monthly. April 5, 2017. Reprinted with permission by First Databank, Inc. All rights reserved. 2017 www.fdbhealth.com/policies/drug-pricing-policy. 4. Price according to walgreens.com. Accessed April 27, 2017.