Factor Analysis. MERMAID Series 12/11. Galen E. Switzer, PhD Rachel Hess, MD, MS

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Factor Analysis MERMAID Series 2/ Galen E Switzer, PhD Rachel Hess, MD, MS

Ways to Examine Groups of Things Groups of People Groups of Indicators Cluster Analysis Exploratory Factor Analysis Latent Class Analysis Confirmatory Factor Analysis (Structural Equation Modeling)

Groups of People vs Groups of Indicators/Items Groups of People Groups of Indicators Group Individual Learning Mentoring Learners Learners Style Quality Mixed Learners Life Stressors Which set of learners is most successful in a traditional medical training environment? Which is the strongest predictor of medical school success?

Latent Structure and Factor Analysis I I I I I I I I I I I I Expertise I Expertise is an unobserved, I I latent construct/concept I I I I I I I I II I I I I I I I Expertise is measured with multiple indicators Expertise could be a single construct or a construct with subdomains I I2 I3 I I4 I5 These subdomains are also referred to as factors Knowledge Experience

SF-2 Example Physical Dimension General health Physical limits on daily activities Physical limits on strenuous activities Physical limits on ability to accomplish things Physical limits on work activities Pain Emotional Health Dimension Emotional limits on ability to accomplish things Emotional limits on work and other activities Calm and peaceful Energy Feeling down Interference with social activities

Factor Analysis in Medical Education Factor Analysis Methods and Validity Evidence: A Systematic Review of Instrument Development Across the Continuum of Medical Education Angela Wetzel; May, 20 Systematic reviews indicate a lack of reporting of reliability and validity evidence in subsets of the medical education literature A comprehensive review of exploratory factor analysis in instrument development across the continuum of medical education had not been previously identified This study is a critical review of instrument development articles employing exploratory factor or principal component analysis published in medical education Data extraction of 64 articles published in the peer-reviewed medical education literature indicates significant errors in the translation of exploratory factor analysis best practices to current practice Instruments reviewed for this study lacked supporting evidence based on relationships with other variables and response process, and evidence based on consequences of testing was not evident Findings suggest a need for further professional development within the medical education researcher community related to ) appropriate factor analysis methodology and reporting and 2) the importance of pursuing multiple sources of reliability and validity evidence to construct a well-supported argument for the inferences made from the instrument Medical education researchers and educators should be cautious in adopting instruments from the literature and carefully review available evidence Finally, editors and reviewers are encouraged to recognize this gap in best practices and subsequently to promote instrument t development research that t is more consistent t through the peer-review process

Two Types of Factor Analysis Exploratory (EFA) link between observed & latent variables unknown Principal Components Factor Analysis max likelihood factoring alpha factoring unweighted least squares generalized least squares Hybrids of FA/PCA principal factors image factoring Confirmatory (CFA) link between observed & latent variables known/hypothesized Factor Analysis Models structural equation methods

Exploratory Factor Analysis Specific Goals reduce the number of indicators/items required to describe a construct assess and improve a measure s s properties provide an operational definition for an underlying construct generate hypotheses

Exploratory Factor Analysis Published Examples Differential behavioral patterns related to alcohol use in rodents: A factor analysis (Salimov, 999) Factor analysis of laboratory and clinical measurements of dyspnea in patients with chronic obstructive pulmonary disease (Nguyen et al, 2003) Morphological abstraction of thyroid tumor cell nuclei using morphometry with factor analysis (Murata et al, 2003) Factor analysis of the interrelationships between clinical variables in horses with colic (Thoefner, et al, 200) Factor analysis shows that female rat behavior is characterized primarily by activity, male rats are driven by sex and anxiety (Fernandes et al, 999)

EFA Terminology Observed variable a variable measured directly Latent variable an unobserved variable that causes observed variables Correlation matrix a table showing all pairs of correlations between observed variables/indicators/items Factor analysis a set of statistical procedures and judgments used to uncover and examine latent variables Factor measurement term for a latent variable Factor loading correlation between an indicator and an underlying factor higher loading means the indicator better represents the factor Eigenvalue a numeric value statistically assigned to each factor that corresponds to how much explanatory power that factor has Scree plot a visual depiction of eigenvalues plotted by factor Rotation a statistical procedure designed to find the cleanest possible factor solution orthogonal or oblique

Observed vs Latent Variables Observed Variables measured directly almost always contain error examples: body mass, lung volume, blood pressure, cell morphology Latent Variables cannot be measured directly (unobserved) cause or produce observed variables examples: student satisfaction, academic success, family stress, burnout latent observed item burnout item 2 item 3

EFA: Steps & Issues Examine descriptive statistics -- indicators on -5 scale Mean Std Dev Analysis N Ind 25 25 040 040 309 Ind 2 5 038 38 Ind 3 42 390 37 Data accurate? Indicators normally distributed? Missing data? Adequate sample size? (good=300, very good=500, excellent=,000)

EFA: Steps & Issues 2 Examine correlation matrix of variables Ind 00 Var Var 2 Var 3 Var 4 Ind 2 040 040 00 00 Ind 3 005 05 00 Ind 4 027 030 068 Variability in sizes of correlations? Matrix factorable? (several > 30) Outliers? (indicators that don t correlate with any others)

EFA: Steps & Issues 3 Examine eigenvalues to decide how many factors to include Factor Initial Eigenvalues Total % of Variance Cumulative % 62 4348 4348 2 784 249 5597 3 0856 599 697 N = 7 items 0000 eigenvalue indicates the % of variance accounted for by the factor provides first evidence of whether Factor Analysis is useful generally identify factors with eigenvalues > 0 as important

Scree Plot Examples 4 Examine scree plot to decide how many factors to extract 6 6 6 5 5 5 4 3 4 3 4 3 2 2 2 2 3 4 5 6 7 8 9 0 No of factors 2 3 4 5 6 7 8 9 0 No of factors 2 3 4 5 6 7 8 9 0 No of factors Plot Plot Plot a b c factors are plotted by eigenvalue important factors are to the left of the scree important factors are to the left of the scree tendency to over-extract using eigenvalues and under-extract using scree plot

5 Rotate the factor solution EFA: Steps & Issues Goal: clarify interpretation by maximizing high and minimizing low factor loadings Factor/Component 2 3 Ind 45 30 2 Ind 2 60 4 02 Ind 3 0 20 20 Ind 4 7 20 30 loading = correlation between indicator and a given factor the matrix above is difficult to interpret

Pain Example Victor, et al, (2008) Clinical Journal of Pain, Jul-Aug;24(6):550-5

EFA: Steps & Issues 7 Determine if the factor solution is adequate patterns should be evident in correlation matrix two or more indicators per factor indicator s loading on its factor should exceed 030 simple structure has been achieved (ie, fewer factors than indicators) examine factors internal consistency reliability in separate alpha analysis

Summary: EFA Steps and Issues Exploratory Factor Analysis examine descriptive statistics examine correlation matrix conduct EFA and examine eigenvalues examine scree plot select rotation type and rotate solution evaluate the adequacy of the final solution

Summary: Exploratory Factor Analysis Exploratory Factor Analysis can be useful for empirically summarizing & reducing data does not involve statistical i significance ifi testing relies on guidelines rather than rigid rules

Confirmatory Factor Analysis General Goals to test a hypothesized set of relationships among observed and unobserved variables to compare factor structure across samples to test construct/factor validity

CFA: Steps & Issues Generate a visual model depict relationships among observed and unobserved variables depict relationships among unobserved variables

stabbing e sharp e2 frozen e3 throbbing e4 hot e5 2 tender e7 sore e6 dull e8 3 achy e9 stiff e0

CFA: Steps & Issues 2 Evaluate Goodness of Fit Indices select appropriate indices GFI, AGFI, CFI etc > 90 RMSEA < 08

CFA: Steps & Issues 3 Evaluate alternate models alternate models from EFA alternate models suggested by CFA compare goodness of fit indices

CFA Fit Indices for Five Models Model GFI AGFI CFI RMSEA Single Factor 937 90 859 076 2 Factor Uncorrelated 97 870 753 0 2 Factor Correlated 944 909 873 073 3 Factor Uncorrelated 862 795 540 34 3 Factor Correlated 966 947 960 04

Three Correlated-Factor Solution for Subgroups Group GFI AGFI CFI RMSEA Total 966 947 960 04 White 934 896 93 06 African American 953 926 999 000

Next Steps evaluate internal consistency of items belonging to a single factor (alpha) create subscales by averaging or summing scores on indicators belonging to a single factor name the factors/subscales use the subscales as predictors or outcomes in other analyses

Factor Subscales as Outcomes Demographics - race/ethnicity - age - SES Psycholosocial - mental health - social support - perceived access Acute Pain Clinical -symptoms - diagnosis

Factor Analysis References Comrey AL, Lee HB A first course in factor analysis, 2 nd ed Hillsdale, NJ: Erlbaum, 992 Gorsuch, RL Factor analysis, 2 nd ed Hillsdale, NJ: Erlbaum, 983 Tabachnick BG, Fidell LS Using multivariate statistics, 5 th ed NY: HarperCollins, 2007 Kline P An easy guide to factor analysis London: Routledge, 994