GLOBAL NEUROSTIMULATION MARKET

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GLOBAL NEUROSTIMULATION MARKET R e p o r t D e s c r i p t i o n T a b l e o f C o n t e n t s L i s t o f T a b l e s S a m p l e T a b l e s R e l a t e d R e p o r t s A b o u t M a r k e t s a n d M a r k e t s MarketsandMarkets Research 108 West 13th Street, Wilmington, DE 19801, County of New Castle Tel. No.: 1-888-989-8004 Email:

Report Description The global market for neurostimulation products is expected to be worth $3.6 billion in 2009, growing at a CAGR of 22.7%, driven by the multiple treatment applications of neurostimulation products, and the emergence of venture capital in the industry. Neurostimulation is used for the treatment of several debilitating conditions, including major treatment-resistant depression, epilepsy, gastroparesis, hearing loss, incontinence, chronic pain, Parkinson s disease, and essential tremors. Neurostimulation systems provide an improved lifestyle alternative to many patients who do not obtain relief from standard drug and invasive surgical therapy. The neurostimulation market is driven mainly by technology advancements, rising consumer awareness, rising age-related neurological disorders, improved clinical outcomes, long-term cost-effectiveness, increased FDA approvals for clinical trials, and the development of sophisticated implantable neurostimulation devices. Currently, there is a huge influx of new players entering into the market, thus leading to increased investments and R&D activities. Implantable neurostimulation devices are increasingly being used for the treatment of a number of chronic disorders such as pain management and epilepsy. Manufacturers are employing developments in low-power semiconductor design, improved manufacturing procedures, and longer battery life for such devices to offer effective, efficient, and long-lasting neurostimulation products. Innovative products such as closed-loop system neurostimulator are designed to continuously stimulate the nervous system. Scope of the Report The report analyzes The Global Biomarker Market into the following segments: Product Market: (Spinal cord stimulator, deep brain stimulator, vagus nerve stimulator, sacral nerve stimulator, and gastric electrical stimulator) Application Market: (Alzheimer s, Parkinson s, chronic heart failure, essential tremors, eye disorders, paralysis, obesity, and other medical conditions ) The market data consists of aggregate sales figures of all neurostimulation submarkets. It analyzes the market aspects of new neurostimulation technologies and product launches; sourcing key market developments from the top companies that it profiles. The report also analyzes the documented claims and the neurostimulation technology patents approved over the last five years to provide an in-depth understanding of neurostimulation product and applications. Technology Market (Minimally-invasive and non-invasive stimulation technology ) 2

Table of Contents 1. Introduction 1.1 Key take aways 1.2. Report description 1.3. Market covered 1.4. Stakeholders 2. The Nervous System 2.1. Types of nervous system disorders 2.3. Sacral nerve disorders 2.2. Brain disorders 2.4. Neurostimulation treatments for neuro-disorders 2.2.1. Seizures/epilepsy 2.2.2. Alzheimer s disease 3. Market Overview of Global Neurostimulation Market 3.1. Defining the neurostimulation product market 3.2.4.2. Gaps in the demand and supply cycle 3.2. Value chain analysis for neurostimulation market 3.2.5. Key competitive points 3.2.1. Demand-side drivers 3.2.5.1. Improved outcomes at competitive prices 3.2.1.1. Longer lasting effect and shorter hospital stays 3.2.5.2. Better brand advertising for treatments and 3.2.1.2. Minimally-invasive technology products 3.2.1.3. Caters to the needs of the aging population 3.3. Product lifecycle & market dynamics 3.2.2. Supply-side drivers 3.3.1. Promotional strategies 3.2.2.1. New market entrants and technology 3.3.2. Channel distribution strategies developments 3.4. Defining the neurostimulation applications market 3.2.2.2. Extensive marketing dynamics 3.5. Neurostimulation technology market 3.2.3. Restraints 3.5.1. Spinalcord stimulator driving the neurostimulation 3.2.3.1. High cost of treatment and lack of surgical skill product market 3.2.3.2. Post-treatment side-effects and prolonged 3.5.2. Alzheimer s and parkinson s driving the egulatory approvals neurostimulation applications market 3.2.4. Opportunities 3.2.4.1. Increasing awareness of neurostimulation in developing countries 4. Global Neurostimulation Product Market 4.1. Drivers 4.2. Spinal cord stimulator 4.1.1. Portability, user-friendliness, & wide-ranging 4.2.1. Drivers applications 4.2.1.1. High efficiency in the treatment of chronic pain 4.1.2. Increasing interest of venture capital firms 4.2.1.2. Cost benefits of spinal cord stimulation 4.1.3. Extensive promotional strategies of major market 4.2.2. Bone growth stimulator players 4.2.3. Spinal cord fusion stimulator 3

Table of Contents 4.3. Deep brain stimulator 4.5.1.2. Shortening of surgical time increases 4.3.1. Drivers revenues for stakeholders 4.3.1.1. Risk-less & flexible alternative to surgery 4.6. Gastric electrical stimulator 4.4. Vagus nerve stimulator 4.6.1. Drivers & restraints 4.5. Sacral nervous stimulator 4.6.1.1. Advantages over conventional treatment 4.5.1. Drivers 4.6.1.2. Gastric stimulation requires special surgical 4.5.1.1. Increase in incidence of urinal and incontinence disorders expertise 5. Neurostimulation Application Market 5.1. Drivers & restraints 5.6. Stroke 5.1.1. Advantages over conventional surgery 5.6.1. Epilepsy 5.1.2. Increase in aging population 5.6.2. Depression 5.1.3. Cost factor & insufficient expertise 5.6.2.1. Drivers & restraints 5.2. Alzheimer s disease 5.6.3. Others strokes 5.2.1. Drivers 5.7. Paralysis 5.2.1.1. Memory improvement & fewer side-effects 5.8. Obesity 5.2.1.2. Absence of an alternate cure for Alzheimer s 5.8.1. Drivers 5.3. Parkinson s disease 5.8.1.1. Increased accuracy in treating morbid obesity 5.4. Pain 5.8.1.2. Reduced cost of hospital stays 5.4.1. Acute pain 5.9. Essential tremors 5.4.2. Chronic pain 5.10. Eye disorders 5.4.2.1. Drivers 5.10.1. Second sight disorders 5.4.2.2. Migraine 5.10.2. Other eye disorders 5.4.2.3. Other chronic pain 5.11. Other neurostimulation applications 5.5. Chronic heart failure (CHF) 5.12. Gastroparesis 5.5.1. Drivers 5.13. Incontinence 6. Global Neurostimulation Technology Market 6.1. Drivers 6.2.2. Transcutaneous electrical neurostimulation 6.2. Minimally-invasive stimulation 6.2.3. Others minimally-invasive neurostimulation 6.2.1. Magnetic nerve stimulation technology 6.2.1.1. Drivers 6.2.1.1.1. Better treatment than anti-depression drugs 6.2.1.1.2. Technology developments supporting market growth 4

Table of Contents 7. Geographic Analysis 7.1. North America 7.2. Europe 7.3. Asia 7.4. Row 8. Competitive Landscape 9. Neurostimulation Patent Analysis 10. Neurostimulation Company Profiles 10.1. Cyberonics, Inc. 10.11. Ndi Medical 10.2. Dynatronics 10.12. Neuronetics, Inc. 10.3. Elekta Ab 10.13. Neuropace 10.4. Enteromedics, Inc. 10.14. Neurotech 10.5. GI Dynamics 10.15. Nexstim 10.6. H. Lundbeck 10.16. RS Medical 10.7. Impulse Dynamics 10.17. St. Jude Medical, Inc. 10.8. Innovative Neurotronics, Inc. 10.18. Synapse Biomedical 10.9. Integra Life Sciences Holdings Corporation 10.19. The Magstim Company Limited 10.10. Medtronic, Inc 10.20. Vertis Neuroscience Appendix 5

List of Tables 1 Global Neurostimulation Market, By Product 2007 2014 27 Global Neurostimulation Market For Other Strokes, ($Millions) By Geography 2007-2014($ Millions 2 Global Neurostimulation Product Market, By Geography 28 Global Neurostimulation Market For Paralysis, 2007 2014 ($ Millions) By Geography 2007-2014 ($ Millions) 3 Global Spinal Cord Stimulator Market, By Product 29 Global Neurostimulation Market For Obesity, By Geography 2009 2014 ($ Millions) 2007-2014 ($ Millions) 4 Global Spinal Cord Stimulator Market, By Geography 30 Global Neurostimulation Market For Essential Tremors, 2007 2014 ($ Millions) By Geography 2007-2014 ($ Millions) 5 Global Bone Growth Stimulator Market, By Geography 31 Global Neurostimulation Applications Market For Eye 2007 2014 ($ Millions) Diseases 2007-2014 ($ Millions) 6 Global Spinal Cord Fusion Stimulator Market, By Geography 32 Global Neurostimulation Market For Eye Diseases, 2007 2014 ($ Millions) By Geography 2007-2014 ($ Millions) 7 Global Deep Brain Stimulator Market, By Geography 33 Global Neurostimulation Market For Second Sight, 2007 2014 ($ Millions) By Geography 2007-2014 ($ Millions) 8 Global Vagus Nerve Stimulator Market, By Geography 34 Global Neurostimulation Market For Other Eye Disorders, 2007 2014 ($ Millions) By Geography 2007-2014 ($ Millions) 9 Global Sacral Nerve Stimulator Market, By Geography 35 Global Other Neurostimulation Applications Market 2007 2014 ($ Millions) 2007-2014($ Millions) 10 Global Gastric Electrical Stimulator Market, By Geography 36 Global Other Neurostimulation Applications Market, 2007 2014 ($ Millions) By Geography 2007-2014($ Millions) 11 Global Neurostimulation Applications Market 2007 2014 37 Global Neurostimulation Market For Gastroparesis, ($ Millions) By Geography 2007-2014($ Millions) 12 Global Neurostimulation Applications Market, By Geography 38 Global Neurostimulation Market For Incontinence, 2007 2014 ($ Millions) By Geography 2007-2014 ($ Millions) 13 Global Alzheimer s Neurostimulation Market, By Geography 39 Global Neurostimulation Technology Market, By Product 2007 2014 ($ Millions) 2007 2014 ($ Millions) 14 Global Parkinson s Neurostimulation Market, By Geography 40 Global Neurostimulation Technology Market, By Geography 2007-2014 ($ Millions) 2007 2014 ($ Millions) 15 Global Neurostimulation Pain Applications Market 41 Global Minimally-invasive Neurostimulation Technology 2007-2014 ($ Millions) Market, By Product 2007 2014 ($ Millions) 16 Global Pain Neurostimulation Market, By Geography 42 Global Minimally-invasive Neurostimulation Technology 2007-2014 ($ Millions) Market, By Geography 2007-2014($ Millions) 17 Global Acute Pain Neurostimulation Market, By Geography 43 Global Minimally-invasive Magnetic Nerve Neurostimulation 2007-2014 ($ Millions) Technology Market, By Geography 2007 2014 ($ Millions) 18 Global Chronic Pain Neurostimulation Market, 44 Global Minimally-invasive Transcutaneous Electrical By Geography 2007-2014 ($ Millions) Neurostimulation Technology Market, By Geography 2007-2014 ($ Millions) 19 Global Chronic Pain Neurostimulation Market, By Geography 2007-2014 ($ Millions) 45 Global Other Minimally-invasive Neurostimulation Market, By Geography 2007 2014 ($ Millions) 20 Global Migraine Neurostimulation Market, By Geography 2007-2014 ($ Millions) 46 Regulatory Approvals In The Neurostimulation Market (2008-2009) 21 Global Other Chronic Pain Neurostimulation Market, By Geography 2007-2014 ($ Millions) 47 New Product Developments In The Neurostimulation Market (2008-2009) 22 Global Chronic Heart Failure Neurostimulation Market, By Geography 2007-2014 ($ Millions) 48 Neurostimulation Patents Filed From 2004 to June 2009 23 Global Neurostimulation Applications Market For Stroke, By Geography 2007-2014 ($ Millions) 24 Global Neurostimulation Applications Market For Stroke, By Geography 2007-2014 ($ Millions) 25 Global Neurostimulation Market For Epilepsy, By Geography 2007 2014 ($ Millions) 26 Global Neurostimulation Market For Depression, By Geography 2007 2014 ($ Millions) 6

List of Figures 1 Neurostimulation Product Market by Total Market Size (2007-2014) 2 Value Chain Analysis for Neurostimulation Market 3 Product Life Cycle Graph of Neurostimulation Market 4 Neurostimulation Applications Market 5 Neurostimulation Product Market Share and Market Growth Matrix Analysis 6 Neurostimulation Application Market Share and Market Growth Rate Matrix Analysis 2009 7 Geogarphical Market Analysis of The Product Market (2009) 8 Regulatory Approvals in The Neurostimulation Market (2008-2009) 9 New Product Launches in The Neurostimulation Market (2008-2009) 10 Neurostimulation Patents Filed Worldwide (2004 To June 2009) 11 Neurostimulation Patents Filed Worldwide for Different Categories (2004 To June 2009) 12 Neurostimulation Patents Filed in North America (2004 To June 2009) 13 Neurostimulation Patents Filed in Europe (2004 To June 2009) 14 Neurostimulation Patents Filed in Asia (2004 To June 2009) 7

Sample Tables Global Neurostimulation Market by Product 2007 2014 ($Millions) Spinal cord stimulator Deep brain stimulator Vagus nerve stimulator Sacral nerve stimulator Gastric electrical stimulator Total 2007 2008 2009 2014 CAGR 2009-2014 Sample Tables Global Neurostimulation Product Market By Geography 2007 2014 ($Millions) North America Europe Asia Row Total 2007 2008 2009 2014 CAGR 2009-2014 Sample Tables Global Neurostimulation Technology Market by Product 2007 2014 ($Millions) Minimum invasive Non invasive Total 2007 2008 2009 2014 CAGR 2009-2014 Sample Tables 8

Sample Tables Global Neurostimulation Applications Market 2007 2014 ($Millions) 2007 2008 2009 2014 CAGR 2009-2014 Alzheimer Parkinson Pain Chronic heart failure Strokes Paralysis Obesity Essential tremors Sample Tables Eye diseases Others Total 9

Key Questions What Makes Our Report Unique? The existing studies and third-party market reports do not provide a comprehensive understanding of the neurostimulation market. The critical markets within this broader field are also not analyzed. This report gives a detailed analysis of the overall market as well as its most critical micro-markets, which have so far remained unexplored. In addition to the comprehensive information on the macro-markets, the report provides market data for up to five levels of the micro-markets under these identified macro markets. Other reports cover only the major technologies or products; and miss out subsequent micro levels. Key Questions Answered Which are the high growth markets segments in terms of products, applications, and technology? What are the market forecasts and estimates from the period 2009-14? What are the major drivers and opportunities in the market? What is the competitive outlook, what are the major products and applications, who are the major players in the market segments? 10

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About MarketsandMarkets We publish about 120 reports a Our clients value our reports year across 10 main industries. especially for the market insight The reports are exhaustive, we provide along with the market detailing about 50 micro markets n u m b e r s. O u r t e a m s o f and product segments, and specialized market analysts and featuring about 80 to 100 market domain experts work within a data summary tables, 50 short structured research process to company profiles, a five-level deliver well-analyzed market market breakdown, overviews of r e p o r t s t o F o r t u n e 1 0 0 0 more than 300 patents, as well as companies globally. analyses of the strategic and competitive landscape. Click here to learn more about us Related Reports Dental Equipment Market (2009-2014) The report provides market data on the latest and future equipment and technologies in the market. It also analyzes the key market trends, strategies of the key players and provides market data for the next five years. The focus is on the patented equipment and technologies being developed across the globe.. Report code: MD 1063 Price: $4650 High Growth Markets in Medical Equipments This report will track market for spinal implant, biological implants, minimal invasive surgey market. The report will identify the investment opportunities within these high growth sectors. The market will be broken down by applications, technologies, products, services and stakeholders providing a comprehensive birds view on each of the high growth market. Report code: MD 1065 Price: $4650 Global Healthcare Information Technology (2009-2014) Each section of the report offers market data with respect to segments and geography. It also provides market trends with respect to drivers, restraints and opportunities. The report contains strategic section with respect to competitive landscape and market overview. The report will encompass more than 40 company profiles. Report code: MD 1069 Price: $4650 12