Unintentional Poisonings: From Data to Action Joint Legislative Health Care Oversight Committee

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Unintentional Poisonings: From Data to Action Joint Legislative Health Care Oversight Committee Dr. Ruth Petersen and Scott Proescholdbell, MPH Chronic Disease and Injury Section Division of Public Health Sept 7, 2010

Leading Causes of N.C. Resident Deaths and Years of Life Lost (2008) Cause of Death Total Deaths Average Years of Life Lost * Total Years of Life Lost * Diseases of Heart 17,417 2.75 47,904 Cancer 17,403 3.41 59,405 Injury 6,275 20.26 127,184 Chronic Lower Respiratory Diseases (Asthma, COPD) 4,527 1.41 6,396 Stroke 4,477 1.97 8,830 Alzheimer's disease 2,620 0.08 204 Diabetes Mellitus 2,164 3.44 7,435 Hypertension 757 2.24 1,692 Atherosclerosis 177 0.59 104 Total Deaths (all causes) 77,057 5.14 396,368 Chronic Disease Deaths 52,219 2.75 143,545 * Based on deaths that occurred prior to age 65 See slide 39 for detailed breakdown of injury deaths and years of life lost Source: Prepared by NC DHHS DPH State Center for Health Statistics March 2010

Deaths from Injury and Violence are Only the Tip of the Iceberg The vast majority of injuries in North Carolina go unreported. 6,275* Deaths 159,645* Hospitalizations 869,435* ED Visits???,??? EMS???,??? Outpatient Visits Despite N.C. s excellent reporting systems, the total burden of injury to the state is unknown.?,???,??? Medically Unattended Injury (home, work, school) INJURY ICEBERG * 2008 death file, hospitalization discharge and NC DETECT (Emergency Department visits)

Leading Causes of Injury Deaths (by Number of Deaths, All Ages, North Carolina Residents: 2008) Motor Vehicle Crashes 1,500 All Suicides 1,160 Unintentional Poisoning 1,016 Unintentional Falls 743 Homicides 664 403 Unint. Other & Unspecified * 216 Unint. Suffocation 113 Unint. Fire/Burn Total Deaths = 6,275 * Unintentional Other and Unintentional Unspecified are two separate categories. Other comprises several smaller defined causes of death, while Unspecified refers to unintentional deaths that were not categorized due to coding challenges. Source: NC State Center for Health Statistics, Death file 2008; Analysis by Injury Epidemiology and Surveillance Unit

Unintentional Poisoning

Poisoning Deaths: N.C., 1999-2009* In 1999, the number of unintentional poisoning deaths was 279; in 2009, the number of deaths had increased to 1,036. Number of Deaths 1,500 1,200 900 600 Unintentional Suicide Homicide Undetermined *Provisional data. 300 All Poisonings Source: N.C. State Center for Health Statistics, Vital Statistics-Deaths, 1999-2009 Analysis by the Injury Epidemiology and Surveillance Unit 0 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 Year

Percent Change in Rates Between 1999 and 2009 Leading Causes of Injury Deaths: N.C. 1999 to 2009* Injury Mech/Intent Firearm - Assault, -25.3% Firearm - Self-Inflicted, +1.7% Unintentional Falls, +68.1% Unintentional Poisoning, +212.7% Motor Vehicle, -28.8% -50 0 50 100 150 200 250 Percent Difference *Provisional data. Source: N.C. State Center for Health Statistics, Vital Statistics-Deaths, 1999-2009 Analysis by Injury Epidemiology and Surveillance Unit

From Data to Action Living lives to their full potential

From Data to Action Basic Demographics, 2008 Male- 66% White- 88% Age group 35 to 54-58%

Rates of Deaths Due to Unintentional Poisonings: N.C. and the United States, 1999-2007 Rates of deaths due to unintentional poisonings are increasing in both the United States and N.C. In 2007, N.C. had a unintentional poisoning rate that was approximately 3% higher than the U.S. Rate per 100,000 population (age-adjusted) 12 10 8 6 4 2 0 199920002001200220032004200520062007 Year U.S. N.C. Source: CDCWISQARS-2006 Analysis by the Injury Epidemiology and Surveillance Unit

Unintentional Poisoning Deaths by County: N.C., 1999-2008 Source: N.C. State Center for Health Statistics, Vital Statistics-Deaths, 1999-2008 Analysis by Injury Epidemiology and Surveillance Unit

Primary Cause of Death Due to Unintentional Poisonings: N.C., 2008 Substance X-Code Number Non-opioid analgesics X40 7 Anti-epileptic and sedativehypnotics X41 33 Narcotics and hallucinogens X42 726 Drugs acting on the autonomic nervous system X43 0 Other /unspecified drugs X44 175 X44 17% X45 6% X40, X46, X47, X48, X49 2% X41 3% Alcohol X45 57 Organic solvents X46 2 Other gases X47 9 Pesticides X48 1 Other/unspecified chemicals X49 6 Narcotics Source: N.C. State Center for Health Statistics, Vital Statistics-Deaths, 2008 Analysis by Injury Epidemiology and Surveillance Unit X42 72%

Number of Times in which a Drug was Mentioned as a Cause of Death: N.C., 2008 1400 1200 All Drugs, 100% Number of Times a Drug is Mentioned as a Cause of Death 1000 800 600 400 200 0 Source: N.C. State Center for Health Statistics, Vital Statistics- Deaths, 2008 Analysis by Injury Epidemiology and Surveillance Unit Cocaine, 14% Heroin, 5% Methadone, 22% Other Drugs, 23% Other Opioids 37% Total Illicit Licit *Categories are not mutually exclusive Includes licit drugs that are misused/abused

Hospital Discharge a, Emergency Department Visits b, and Carolinas Poison Center Calls c Due to Unintentional Poisonings: N.C., 2007 Hospital discharges, emergency department (ED) visits, and calls to the Carolinas Poison Center (CPC) are far more common than deaths due to unintentional poisonings. asource: N.C. State Center for Health Statistics, Vital Statistics-Deaths 2007 bnc DETECT-ED-2007 Analysis by the Injury Epidemiology and Surveillance Unit ccpc 2007 Analysis by CPC Gender: Hospital Discharges Emergency Dept. Visits Carolinas Poison Center Calls Number Rate Number Rate Number Rate Male: 1,618 36.5 4,105 92.7 31,442 710.1 Female: 1,827 39.4 4,591 99.1 31,970 690.0 Total: 3,445 38.0 8,696 96.0 63,412 699.8 Age Group (Years) 00-04 149 23.4 1,823 285.9 37,059 5,811.7 05-09 22 3.5 294 48.1 5,075 795.9 10-14 19 * 203 34.2 2,131 359.0 15-19 118 19.0 594 95.8 1,627 262.4 20-24 163 26.7 598 98.0 1,900 311.4 25-34 356 29.2 1,091 89.5 3,520 288.7 35-44 584 43.5 1,232 91.9 3,441 256.5 45-54 725 55.7 1,181 90.8 2,929 225.2 55-64 527 51.5 733 71.6 2,375 232.1 65-74 399 67.4 466 78.7 1,598 270.0 75-84 278 75.4 331 89.7 1,117 302.8 85+ 105 73.6 150 105.2 525 368.1 Total: 3,445 37.9 8,696 96.0 63,297 696.5

Causes of Unintentional Poisoning, NC DETECT: January June, 2010* (ED Visits = 6, 828) Other & Unspecified Substances 5% Gases/Vapors 11% Poisonous Foodstuffs/Plants 16% Drugs (over-the-counter, prescription, and illicit drugs) were mentioned in 61% of ED visits due to unintentional poisonings. Corrosives Cleansing 3% Agents 2% Alcohol 2% *Provisional data: final diagnoses may take up to three months. Drugs 61% Source: NC DETECT, 2009 Analysis by Injury Epidemiology and Surveillance Unit

The Ten Most Frequently Cited Drugs in ED Visits Due to Unintentional Poisonings, NC DETECT : 2010* 600 570 553 500 400 300 200 284 258 251 201 167 163 161 136 Number of ED Visits 100 0 Benzodiazepines Other Opioids Aromatic Analgesics Cardiovascular Agents Hormone Substitutes Antidepressants Other Sedatives/Hypnotics CNS Stimulants Systemic Agents Smooth/Skeletal Muscle Agents Drug Type *Provisional data Jan-June: final diagnoses may take up to three months. Source: NC DETECT, 2009 Analysis by Injury Epidemiology and Surveillance Unit

From Data to Action- YRBS YRBS= Youth Risk Factor Surveillance System

Unintentional Poisonings 1,016* Deaths 3,445* Hospitalizations 8,696* ED Visits???,??? EMS???,??? Outpatient Visits?,???,??? Medically Unattended Injury (home, work, school) INJURY ICEBERG * 2008 death file, 2007 hospitalization discharge and NC DETECT (Emergency Department visits)