PBS PRICE INCREASES - AUGUST 2014 SCHEDULE

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Price increase review - general PBS benzylpenicillin 600 mg injection, 1 x 600 mg vial 1775K, 3398W, BenPen 3.84 4.38 3486L benzylpenicillin 3 g injection, 1 x 3 g vial 2647H, 3399X, BenPen 6.60 7.55 3487M busulfan 2 mg tablet, 100 1128J Myleran 72.58 81.29 chlorambucil 2 mg tablet, 25 1163F Leukeran 29.90 33.49 diazepam 10 mg/2 ml injection, 5 x 2 ml ampoules 2558P, 5073B, Hospira Pty Limited brand 5.10 6.02 3458B medroxyprogesterone acetate 5 mg tablet, 57 2323G Ralovera 7.19 8.00 Provera (premium brand) 8.89 10.25 medroxyprogesterone acetate 100 mg tablet, 100 2725K Provera 76.33 87.63 medroxyprogesterone acetate 200 mg tablet, 60 2316X Provera 86.70 99.69 medroxyprogesterone acetate 250 mg tablet, 60 2727M Provera 108.39 125.11 medroxyprogesterone acetate 500 mg tablet, 30 2728N Provera 108.60 125.11 medroxyprogesterone acetate 150 mg/ml injection, 1 x 1 ml vial 3118D Depo-Ralovera 12.93 14.13 Depo-Provera (premium brand) 15.71 17.17 melphalan 2 mg tablet, 25 2547C Alkeran 39.97 63.95 mercaptopurine 50 mg tablet, 25 1598D Purinethol 56.88 60.59 nedocromil sodium 2 mg/actuation inhalation: pressurised, 112 actuations 8365G Tilade CFC-Free 27.19 29.08 nicorandil 10 mg tablet, 60 8228C Ikorel 15.41 16.64 nicorandil 20 mg tablet, 60 8229D Ikorel 21.60 23.18 thioguanine 40 mg tablet, 25 1233X Lanvis 174.76 218.45 Price increase review - section 100 highly specialised drugs program apomorphine hydrochloride 20 mg/2 ml injection, 5 x 2 ml ampoules 9607P, 5609F Apomine 77.86 99.95 apomorphine hydrochloride 50 mg/5 ml injection, 5 x 5 ml ampoules 9640J, 5610G Apomine 194.65 250.10 Price increase review - section 100 efficient funding of chemotherapy program cyclophosphamide (as monohydrate) 500 mg injection: powder for, 1 x 500 mg vial 7226H, 4327R Endoxan 13.86 19.23 cyclophosphamide (as monohydrate) 1 g injection: powder for, 1 x 1 g vial 7226H, 4327R Endoxan 21.21 29.42 cyclophosphamide (as monohydrate) 2 g injection: powder for, 1 x 2 g vial 7226H, 4327R Endoxan 42.43 58.85 ifosfamide 1 g injection: powder for, 1 x 1 g vial 7248L, 4448D Holoxan 59.15 60.53 ifosfamide 2 g injection: powder for, 1 x 2 g vial 7248L, 4448D Holoxan 118.40 121.07 raltitrexed 2 mg injection: powder for, 1 x 2 mg vial 7256X, 4610P Tomudex 253.34 320.97

Price increase resulting from alteration of manufacturer's pack ticarcillin 3 g + clavulanic acid 100 mg injection, 1 x 3.1 g vial (manufacturer's pack size altered from 10 to 1) 10113G, 10125X Timentin 142.64 (pack of 10) 14.27 (pack of 1) Price increases affecting premium brands only aciclovir 200 mg tablet, 25 1003T Zovirax 200 mg 13.75 13.90 aciclovir 200 mg tablet, 90 1007B Zovirax 200 mg 47.62 48.06 aciclovir 800 mg tablet, 35 1052J Zovirax 800 mg 56.66 56.87 amlodipine 5 mg tablet, 30 2751T Norvasc 4.05 6.37 amlodipine 10 mg tablet, 30 2752W Norvasc 6.44 9.85 amoxycillin 250 mg capsule, 20 1884E, 3301R Amoxil 3.13 3.70 amoxycillin 500 mg capsule, 20 1889K, 3300Q Amoxil 3.89 4.60 amoxycillin 125 mg/5 ml oral liquid: powder for, 100 ml 1886G, 3302T Amoxil 3.03 3.60 amoxycillin 250 mg/5 ml oral liquid: powder for, 100 ml 1887H, 3393N Amoxil Forte 3.34 3.96 amoxycillin 500 mg + clavulanic acid 125 mg tablet, 10 1891M, 5008N Augmentin Duo 5.31 6.18 amoxycillin 875 mg + clavulanic acid 125 mg tablet, 10 8254K, 5006L Augmentin Duo forte 7.05 8.20 amoxycillin 125 mg/5 ml + clavulanic acid 31.25 mg/5 ml oral liquid: powder for, 75 ml 1892N, 5009P Augmentin 3.59 4.19 amoxycillin 400 mg/5 ml + clavulanic acid 57 mg/5 ml oral liquid: powder for, 60 ml 8319W, 5011R Augmentin Duo 400 5.07 5.92 candesartan cilexetil 4 mg tablet, 30 8295N Atacand (new brand premium) 1.84 3.58 candesartan cilexetil 8 mg tablet, 30 8296P Atacand (new brand premium) 5.49 7.23 candesartan cilexetil 16 mg tablet, 30 8297Q Atacand (new brand premium) 16.43 18.17 candesartan cilexetil 32 mg tablet, 30 8889W Atacand (new brand premium) 19.86 21.60 candesartan cilexetil 16 mg + hydrochlorothiazide 12.5 mg tablet, 30 8504N Atacand Plus 16/12.5 (new brand premium) 18.05 19.79 candesartan cilexetil 32 mg + hydrochlorothiazide 12.5 mg tablet, 30 9314F Atacand Plus 32/12.5 (new brand premium) 21.48 23.22 candesartan cilexetil 32 mg + hydrochlorothiazide 25 mg tablet, 30 9315G Atacand Plus 32/25 (new brand premium) 23.11 24.85 cefaclor 375 mg tablet: modified release, 10 1169M, 5045M Ceclor CD 8.47 9.59 cefaclor 125 mg/5 ml oral liquid: powder for, 100 ml 2460L, 5046N Ceclor 6.56 7.43 cefaclor 250 mg/5 ml oral liquid: powder for, 75 ml 2461M, 5047P Ceclor 6.90 7.82 cephalexin 250 mg capsule, 20 3058Y, 3317N, Keflex 4.15 4.74 2655R cephalexin 500 mg capsule, 20 3119E, 3318P Keflex 6.38 7.24 cephalexin 125 mg/5 ml oral liquid: powder for, 100 ml 3094W, 3319Q Keflex 4.68 5.32 cephalexin 250 mg/5 ml oral liquid: powder for, 100 ml 3095X, 3320R Keflex 6.30 7.16 citalopram 20 mg tablet, 28 8220P Cipramil 4.27 6.48

clindamycin 150 mg capsule, 24 3138E, 5057E Dalacin C 12.78 13.36 doxepin 10 mg capsule, 50 1011F Sinequan 4.74 5.53 doxepin 25 mg capsule, 50 1013H Sinequan 4.85 5.53 doxycycline 50 mg capsule: modified release, 25 capsules 2707L Mayne Pharma Doxycycline (new brand premium) 1.97 3.39 doxycycline 100 mg capsule: modified release, 7 capsules 2708M, 3322W, Mayne Pharma Doxycycline (new brand premium) 1.11 1.97 2703G doxycycline 100 mg capsule: modified release, 21 capsules 2715X Mayne Pharma Doxycycline (new brand premium) 3.32 5.28 escitalopram 10 mg tablet, 28 8700X, 9432K Lexapro 7.66 10.25 escitalopram 20 mg tablet, 28 8701Y, 9433L Lexapro 8.89 11.09 fluvoxamine maleate 50 mg tablet, 30 8512B Luvox 8.74 10.25 fluvoxamine maleate 100 mg tablet, 30 8174F Luvox 12.46 13.97 frusemide 20 mg tablet, 50 1810G Lasix-M 1.47 1.60 frusemide 40 mg tablet, 100 2412Y Lasix 3.15 3.49 glipizide 5 mg tablet, 100 2440K Minidiab 8.42 9.01 indomethacin 25 mg capsule, 50 2454E, 5126T, Indocid 3.69 4.63 5379D, 5377B lactulose mixture 3.34 g per 5 ml, 500 ml, 1 3064G, 5388N, Actilax (new brand premium) 3.43 4.20 5387M lamotrigine 5 mg tablet, 56 8063J Lamictal 5.63 6.57 lamotrigine 25 mg tablet, 56 2848X Lamictal 11.23 13.07 lamotrigine 50 mg tablet, 56 2849Y Lamictal 18.15 19.50 lamotrigine 100 mg tablet, 56 2850B Lamictal 29.28 30.86 lamotrigine 200 mg tablet, 56 2851C Lamictal 48.41 50.01 lercanidipine hydrochloride 10 mg tablet, 28 8534E Zanidip 5.01 6.16 lercanidipine hydrochloride 20 mg tablet, 28 8679T Zanidip 7.09 8.24 medroxyprogesterone acetate 10 mg tablet, 30 2321E Provera 8.57 9.01 medroxyprogesterone acetate 10 mg tablet, 100 2722G Provera 24.60 25.10 meloxicam 7.5 mg tablet, 30 8561N Mobic 6.43 7.50 meloxicam 15 mg tablet, 30 8562P Mobic 8.87 9.93 meloxicam 7.5 mg capsule, 30 8887R Mobic 6.43 7.50 meloxicam 15 mg capsule, 30 8888T Mobic 8.87 9.93 metformin hydrochloride 500 mg tablet, 100 2430X Diabex 4.31 5.01 metformin hydrochloride 850 mg tablet, 60 1801T Diabex 850 4.31 5.01 metformin hydrochloride 1 g tablet, 90 8607B Diabex 1000 6.86 7.53 metformin hydrochloride 500 mg tablet: modified release, 120 tablets 9435N Diabex XR (new brand premium) 5.44 7.05 paroxetine 20 mg tablet, 30 2242B Aropax 7.29 8.21 perindopril arginine 2.5 mg tablet, 30 9006B Coversyl 2.5mg (new brand premium) 2.95 4.64 PREXUM 2.5 (new brand premium) 2.95 4.64 piroxicam 20 mg tablet: dispersible, 25 1896T, 5202T Feldene-D 7.35 8.14

piroxicam 10 mg capsule, 50 1897W. 5203W Feldene 7.23 7.70 piroxicam 20 mg capsule, 25 1898X, 5204X Feldene 6.95 7.27 prochlorperazine maleate 5 mg tablet, 25 2893G, 5205Y Stemetil 3.99 4.58 salbutamol 2.5 mg/2.5 ml inhalation: solution, 30 x 2.5 ml ampoules 2000G, 3496B Ventolin Nebules 4.45 4.52 salbutamol 5 mg/2.5 ml inhalation: solution, 30 x 2.5 ml ampoules 2001H, 3497C Ventolin Nebules 4.67 4.71 spironolactone 25 mg tablet, 100 2339D Aldactone 6.54 7.27 spironolactone 100 mg tablet, 100 2340E Aldactone 21.83 22.49 sulfasalazine tablet 500 mg (enteric coated), 100 2096H, 9209Q Salazopyrin-EN 22.64 22.87 sumatriptan tablet 50 mg (as succinate), 2 8144P Imigran 5.53 6.31 sumatriptan tablet (fast disintegrating) 50 mg (as succinate), 2 8885P Imigran FDT (new brand premium) 5.01 6.31 tinidazole 500 mg tablet, 4 1465D Fasigyn 5.90 6.41 tramadol hydrochloride 50 mg capsule, 20 8455B, 8611F, Tramal 2.97 3.27 5232J tramadol hydrochloride 100 mg tablet: modified release, 20 tablets 8523N Tramal SR 100 6.50 7.09 tramadol hydrochloride 150 mg tablet: modified release, 20 tablets 8524P Tramal SR 150 8.24 8.95 tramadol hydrochloride 200 mg tablet: modified release, 20 tablets 8525Q Tramal SR 200 9.71 10.50 valproate sodium 200 mg tablet: enteric, 100 2289L Epilim EC 8.82 9.00 valproate sodium 500 mg tablet: enteric, 100 2290M Epilim EC 16.88 17.08

PBS PRICE REDUCTIONS - AUGUST 2014 SCHEDULE (S) Price disclosure reductions Riluzole 50 mg tablet, 56 8664B APO-Riluzole; Rilutek; Riluzole Sandoz 529.51 426.74 Price reductions due to addition of new brand (balance of staged F2 reduction) esomeprazole 20 mg tablet: enteric, 30 tablets 8886Q, 8600P Esomeprazole RBX (new brand) - 16.18 Nexium 20.54 16.18 esomeprazole 40 mg tablet: enteric, 30 tablets 8601Q, 3401B Esomeprazole RBX (new brand) - 27.44 Nexium 34.77 27.44 Flow on of above reductions esomeprazole 20 mg tablet: enteric [14 tablets] (&) clarithromycin 500 mg tablet [14 tablets] (&) amoxycillin 500 mg capsule [28 capsules], 1 pack 8738X Nexium Hp7 47.61 42.49 Price reductions due to addition of new brands - general PBS calcium tablet (chewable) 500 mg (as carbonate), 60 3116B; Cal-500 (new brand) - 4.89 4333C, 4094L Cal-Sup 5.83 4.89 capecitabine 150 mg tablet, 60 8361C Capecitabine Actavis; Capecitabine Alphapharm; Capecitabine- - 89.74 DRLA; Capecitabine Sandoz (new brands) Xeloda 106.83 89.74 capecitabine 500 mg tablet, 120 8362D Capecitabine Actavis; Capecitabine Alphapharm; Capectitabine Apotex; Capecitabine-DRLA; Capecitabine GH; Capecitabine Sandoz (new brands) - 556.30 Xeloda 662.26 556.30 metoprolol succinate tablet 23.75 mg (controlled release), 15 8732N Metrol-XL 23.75; Minax XL (new brands) - 10.68 Toprol-XL 23.75 12.71 10.68 metoprolol succinate tablet 47.5 mg (controlled release), 30 8733P Metrol-XL 47.5; Minax XL (new brands) - 50.44 Toprol-XL 47.5 60.04 50.44 metoprolol succinate tablet 95 mg (controlled release), 30 8734Q Metrol-XL 95; Minax XL (new brands) - 63.03 Toprol-XL 95 75.04 63.03 metoprolol succinate tablet 190 mg (controlled release), 30 8735R Metrol-XL 190; Minax XL (new brands) - 78.79 Toprol-XL 190 93.80 78.79 tirofiban 12.5 mg/50 ml injection, 1 x 50 ml vial 8350L Tirofiban AC (new brand) - 284.50 Aggrastat 338.69 284.50

PBS PRICE REDUCTIONS - AUGUST 2014 SCHEDULE (S) Price reductions due to addition of new items or new brands - section 100 highly specialised drugs program epoprostenol 500 microgram injection, 1 x 500 microgram vial 10111E, 10130E Veletri (new item) - 33.28 epoprostenol sodium powder for I.V. infusion 500 micrograms (base) 5036C, 5030R Flolan Kit 39.62 33.28 infusion administration set, 1 epoprostenol 1.5 mg injection, 1 x 1.5 mg vial 10129D, 10117L Veletri (new item) - 66.55 epoprostenol sodium powder for I.V. infusion 1.5 mg (base) infusion 5042J, 5035B Flolan Kit 79.23 66.55 administration set, 1 omalizumab 75 mg/0.5 ml injection, 1 x 0.5 ml syringe 10110D, 10118M Xolair (new item) - 250.00 omalizumab 150 mg/ml injection, 1 x 1 ml syringe 10122R, 10109C Xolair (new item) - 357.00 omalizumab 150 mg injection [1 x 150 mg vial] (&) inert substance diluent 9746Y, 9745X Xolair 425.00 357.00 [1 x 1.2 ml ampoule], 1 pack sildenafil 20 mg tablet, 90 9605M, 9547L APO-Sildenafil PHT; Sildenafil Sandoz PHT 20 (new brands) - 754.68 Revatio 898.43 754.68 Reduction due to lower price offer folic acid 500 microgram tablet, 100 2958Q Foltabs 500; Megafol 0.5 2.37 2.14 Price decreases due to removal of therapeutic group premium telmisartan 40 mg tablet, 28 8355R Micardis 7.84 5.67 telmisartan 80 mg tablet, 28 8356T Micardis 18.60 16.43 Price decreases due to removal of brand premium norethisterone 350 microgram tablet, 112 [4 x 28] 1967M Noriday 28 Day 12.12 8.73 telmisartan 40 mg + hydrochlorothiazide 12.5 mg tablet, 28 8622T Micardis Plus 40/12.5 mg 9.36 7.18 telmisartan 80 mg + hydrochlorothiazide 12.5 mg tablet, 28 8623W Micardis Plus 80/12.5 mg 20.12 17.95 telmisartan 80 mg + hydrochlorothiazide 25 mg tablet, 28 9381R Micardis Plus 80/25 mg 21.64 19.46