POSTGRADUATE COURSE MOC 8 MOC MARCH 10-12, 2017 ACG S HEPATOLOGY SCHOOL & WESTERN REGIONAL CME REGISTER EARLY AND SAVE! MEETINGS.GI.

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2017 ACG S HEPATOLOGY SCHOOL & WESTERN REGIONAL POSTGRADUATE COURSE THE COSMOPOLITAN OF LAS VEGAS REGISTER EARLY AND SAVE! MEETINGS.GI.ORG MARCH 10-12, 2017 ACG S HEPATOLOGY SCHOOL EARN CME UP TO 8 CREDITS EARN 8 MOC UP TO POINTS POSTGRADUATE COURSE EARN CME UP TO 12.25 CREDITS EARN UP TO 12.2 5 MOC POINTS

2017 ACG S HEPATOLOGY SCHOOL AND WESTERN REGIONAL POSTGRADUATE COURSE FRIDAY, MARCH 10, 2017 ACG s Hepatology School SATURDAY AND SUNDAY, MARCH 11 12, 2017 Western Regional Postgraduate Course LEARN AND EARN CME AND MOC WHILE YOU STAY AND PLAY IN LAS VEGAS Join colleagues at the 2017 Western Regional Postgraduate Course to hear leading experts and rising stars in the field of gastroenterology discuss common questions on bloating, heartburn, 2 REGISTER EARLY AND SAVE! MEETINGS.GI.ORG

March 10-12, 2017 THE COSMOPOLITAN OF LAS VEGAS, LAS VEGAS, NEVADA constipation, fecal incontinence, traveler s diarrhea, and cannabis. Stateof-the-art updates on IBD, FMT, obesity, pancreatic cancer, endoscopy, and practice management and medicine in general will be joined with the latest and greatest in hands-on sessions in this engaging two day program. On Friday, March 10, prior to the start of the weekend course, the College will offer its NEW one-day program, ACG s Hepatology School. Hear the experts discuss the latest in liver disease and hepatitis management. Stay abreast of the therapeutic advances and ways to manage patients. Relax and unwind when you attend the ACG Western Regional Postgraduate Course. Both programs will take place at The Cosmopolitan of Las Vegas in Las Vegas, Nevada. Centrally located on the Las Vegas Strip next to the Bellagio and across from Paris, you can also enjoy world-class entertainment, dynamic nightlife, a gourmand s paradise, and some casino action while attending the course. ATTENDEES: USE THE ACG MOBILE APP TO ACCESS FACULTY PRESENTATIONS 3

ACG S HEPATOLOGY SCHOOL EDUCATIONAL AGENDA Course Directors David E. Bernstein, MD, FACG, and Mitchell L. Shiffman, MD, FACG Friday 4 FRIDAY, MARCH 10, 2017 7:00 am Registration / Continental Breakfast 8:00 am Welcome and Introductions David E. Bernstein, MD, FACG, and Mitchell L. Shiffman, MD, FACG 8:10 am HBV Natural History and Management Mitchell L. Shiffman, MD, FACG Discuss the natural history of hepatitis B, HBV serologies, the different immune stages of the disease, and screening recommendations for HCC in patients with HBV. 8:35 am HBV Treatment Tram T. Tran, MD, FACG Explain current recommendations for the treatment of HBV and summarize the use of anti-hbv drugs to minimize transmission risk during pregnancy and to prevent reactivation of occult HBV during immunosuppression. 9:00 am Q & A 9:15 am HCV Epidemiology, Screening, Natural History, and Extra-Hepatic Manifestations Mark W. Russo, MD, MPH, FACG Describe the epidemiology of HCV, screening recommendations, and the natural history of HCV, as well as potential impacts on other organs. 9:40 am HCV Treatment of Genotype 1: Now and in the Future David E. Bernstein, MD, FACG Summarize the current and future management options for patients with HCV genotype 1, including patients with cirrhosis. 10:05 am Refreshment Break 10:25 am HCV Treatment of Genotypes 2-6: Now and in the Future Joseph K. Lim, MD, FACG Analyze the current and future management options for patients with HCV genotypes 2-6, including cirrhosis. 10:50 am HCV Retreatment of DAA Failures Tram T. Tran, MD, FACG Identify how to approach patients who have failed HCV treatment with the current DAA therapies and the role viral mutations/resistance may play in this process. 11:15 am Treatment of Patients With Decompensated Cirrhosis and Liver Transplant Recipients Paul Y. Kwo, MD, FACG Differentiate HCV treatment in patients with decompensated cirrhosis, determine which patients should not be treated, and describe strategies for managing HCV after liver transplantation.

REGISTER EARLY AND SAVE! MEETINGS.GI.ORG 11:40 am The Impact of Curing HCV on the Liver and its Extra-Hepatic Manifestations Joseph K. Lim, MD, FACG List how HCV impacts other organs outside the liver and the impact of curing HCV on these extra-hepatic manifestations. 12:05 pm Lunch with Faculty and Case Presentations / Q & A Mitchell L. Shiffman, MD, FACG 1:30 pm Treating and Monitoring Chronic HCV and Other Liver Diseases The Role of the NP in Clinical Practice April G. Morris, FNP Outline the role of NPs in working with patients with liver diseases to prepare them for treatment, obtain medication approval from insurance carriers, and monitor them during treatment. 1:55 pm Update on NAFLD Mark W. Russo, MD, MPH, FACG Describe the epidemiology, natural history, disease progression, mortality risk, and treatment options of NAFLD, and how it differs from NASH. 2:20 pm Disorders of Iron Metabolism in Patients With Liver Disease Joseph K. Lim, MD, FACG Describe disorders of iron metabolism and their diagnosis and treatment. 2:45 pm Primary Biliary Cholangitis Mitchell L. Shiffman, MD, FACG Explain the epidemiology, natural history, treatment, and extra-hepatic manifestations of primary biliary cholangitis. 3:10 pm Refreshment Break 3:25 pm Hepatic Encephalopathy David E. Bernstein, MD, FACG Identify the classification, diagnostic testing, effect on morbidity and mortality, and treatment of hepatic encephalopathy. 3:50 pm Other Complications of Cirrhosis Tram T. Tran, MD, FACG Recognize complications of cirrhosis including ascites, hyponatremia, HRS, and variceal bleeding. 4:15 pm Hepatocellular Carcinoma Paul Y. Kwo, MD, FACG List risk factors, screening and evaluation methods, treatments, and outcome for patients with hepatocellular carcinoma. 4:40 pm Case Presentations / Q & A 5:20 pm Wrap-up David E. Bernstein, MD, FACG, and Mitchell L. Shiffman, MD, FACG 5:30 pm Adjourn 5

WESTERN REGIONAL POSTGRADUATE COURSE EDUCATIONAL AGENDA Course Directors Saturday Simon K. Lo, MD, FACG, and Darrell D. Wadas, MD, FACG SATURDAY, MARCH 11, 2017 6:30 am Registration and Continental Breakfast in the Exhibit Hall 7:30 am Welcome Remarks and Announcements Simon K. Lo, MD, FACG, and Darrell D. Wadas, MD, FACG SESSION 1: COMMON GI QUESTIONS Moderator: John E. Pandolfino, MD, MSCI, FACG 7:35 am Heartburn John E. Pandolfino, MD, MSCI, FACG Analyze new surgical concepts available for the management of GERD. 7:55 am Cannabis What the Gastroenterologist Should Know Mark E. Gerich, MD Identify uses of cannabis for the treatment of gastrointestinal disorders and the medicolegal issues related to prescribing cannabis. 8:15 am Chronic Bloating Lin Chang, MD, FACG Describe the causes and treatment of small bowel fungal overgrowth, irritable bowel syndrome, and microbiome-linked disease. 8:35 am Panel Discussion / Q & A 6

REGISTER EARLY AND SAVE! MEETINGS.GI.ORG SESSION 2: EVERYTHING YOU NEED TO KNOW ABOUT BOWEL MOVEMENTS Moderator: Amy E. Foxx-Orenstein, DO, FACG 8:55 am Evaluation of Constipation William D. Chey, MD, FACG Explain when and how to evaluate constipation. 9:15 am Treatment Regimens for Chronic Constipation: What s Good, What s Acceptable, and What s Bad? Amy E. Foxx-Orenstein, DO, FACG Compare and contrast treatment regimens for chronic constipation. 9:35 am Clinical Assessment and Practical Approach for Treating Fecal Incontinence Lawrence R. Schiller, MD, MACG Discuss the assessment of fecal incontinence and appropriate use of ancillary testing in its evaluation. 9:55 am Traveler s Diarrhea: Prevention, Treatment, and Post-infection Symptoms Mark S. Riddle, MD Apply the appropriate recommendations for the evaluation and treatment of traveler s diarrhea. 10:15 am Panel Discussion / Q & A 10:35 am Break / Visit the Exhibit Hall SESSION 3: THE GASTROENTEROLOGIST S ROLE IN OBESITY Moderator: John K. DiBaise, MD, FACG 10:55 am Holistic Approach to Obesity Robin P. Blackstone, MD, FACS, FASMBS Identify new ways to address obesity, including medical and surgical treatment. 11:15 am Endoscopic Management of Bariatric Surgery Complications John K. DiBaise, MD, FACG Outline the various complications that can result from bariatric surgery and the appropriate endoscopic treatments for the management of each complication. 11:35 am Endoscopic Treatment of Obesity: Should We Do It? Christopher C. Thompson, MD, MSc, FACG Recognize the various options for the endoscopic treatment of obesity, and the benefits and limitations of each. 11:55 am Panel Discussion / Q & A 12:15 pm Break / Lunch 12:40 pm Working Luncheon Presentation: Challenging GI Bleeding Conditions Lisa L. Strate, MD, MPH, FACG Evaluate malignant ulcers and discuss obscure bleeding brought on by anticoagulation or antiplatelet therapy. 1:40 pm Break / Dessert in the Exhibit Hall 7

WESTERN REGIONAL POSTGRADUATE COURSE EDUCATIONAL AGENDA (cont.) SATURDAY AFTERNOON GENERAL SESSIONS/ HANDS-ON WORKSHOP SESSIONS*: 2:00-2:45 pm The Latest Surgical Options for Severe GERD Lauren B. Gerson, MD, MSc, FACG Analyze new surgical concepts available for the management of GERD. OR Hands-on Workshop Session* 2:55-3:40 pm What s New With FMT? Neil H. Stollman, MD, FACG Recognize the appropriate patient for FMT, interpret the evidence supporting FMT, and explain the logistics for performing FMT. OR Hands-on Workshop Session* 3:50-4:35 pm Practice Management in 2017 Costas H. Kefalas, MD, MMM, FACG Compare MIPS and APMs, Medicare s two Quality Payment Programs. OR Hands-on Workshop Session* 8 4:45-5:30 pm Evaluation and Emerging Therapies for Fatty Liver Disease Violeta B. Popov, MD, PhD Explain screening, diagnosis, and staging of fatty liver disease, and describe emerging therapies for non-alcoholic steatohepatitis. OR Hands-on Workshop Session* HANDS-ON STATIONS* x Regional Courses Hands-on Workshop Directors: Qiang Cai, MD, PhD, FACG, and Shivangi T. Kothari, MD x Mucosal Ablation: RFA Mucosal Ablation: Cryotherapy Enteroscopy EMR ERCP Hemorrhoid Therapy Hemostasis Foreign Body Removal *Hands-on Workshop sessions do not offer CME. Sunday SUNDAY, MARCH 12, 2017 7:00 am Registration and Continental Breakfast in the Exhibit Hall 7:55 am Welcome and Announcements Simon K. Lo, MD, FACG, and Darrell D. Wadas, MD, FACG SESSION 4: ENDOSCOPY IN GI PRACTICE Moderator: Simon K. Lo, MD, FACG 8:00 am Endoscopic Evaluation and Treatment of Rectal Bleeding in the Setting of Diverticulosis Shivangi T. Kothari, MD Describe the approaches to evaluating and treating rectal bleeding involving diverticulosis, which can be quite challenging in clinical practice. 8:20 am Non-esophageal Varices: What Should We Do? Simon K. Lo, MD, FACG Recognize the various types of nonesophageal varices and the current clinical recommendations for each.

REGISTER EARLY AND SAVE! MEETINGS.GI.ORG 8:40 am Recognition and Management of Flat Lesions in the Colon List the types of flat lesions commonly and less commonly seen in the colon, and techniques to improve their detection. 9:00 am Cryotherapy: Is it Ready for Prime Time? Michael S. Smith, MD, MBA Discuss the current state of cryotherapy and the applications for cryotherapy in the GI tract. 9:20 am Panel Discussion / Q & A 9:40 am Refreshment Break / Visit the Exhibit Hall SESSION 5: PANCREATIC CANCER Moderator: Simon K. Lo, MD, FACG 10:00 am Risk Factors, Screening, and Diagnostic Approaches for Pancreatic Cancer Simon K. Lo, MD, FACG Identify patient groups and factors that increase the risk of pancreatic cancer, and explain screening and diagnostic approaches for individuals with these increased risk factors. 10:20 am Personalized Medicine in Pancreatic Cancer: What s on the Horizon? Lynn M. Matrisian, PhD, MBA Evaluate current and future personalized medicine approaches for the assessment and treatment of pancreatic cancer. 10:40 am Panel Discussion / Q & A SESSION 6: UPDATES FOR 2017 Moderator: William D. Chey, MD, FACG 11:00 am 5 New Things Every Gastroenterologist Should Know About IBD in 2017 Lisa B. Malter, MD, FACG Translate recent advances in IBD into meaningful changes to managing patients. 11:20 am The Future of Medicine in 2017 William D. Chey, MD, FACG Appraise the current trends in medicine and predict what emerging technologies and techniques will be important for the field of gastroenterology in the future. 11:40 am Panel Discussion / Q & A 12:00 pm Course Wrap-up and Take-away Points Simon K. Lo, MD, FACG, and Darrell D. Wadas, MD, FACG 12:15 pm Course Adjourns 9

GENERAL INFORMATION PROGRAM DESCRIPTIONS ACG S HEPATOLOGY SCHOOL After completing ACG s Hepatology School, attendees will be able to identify appropriate candidates for hepatitis therapy, describe the pre-treatment evaluation, recommend appropriate therapies for naïve and previously treated hepatitis C patients based on genotype and be able to address the side effects of these therapies, and understand the timeline of new drug development for the treatment of hepatitis C infection. Participating in this educational activity will also enable learners to analyze the challenges in treating patients with NAFLD, disorders of iron metabolism, primary biliary cholangitis, hepatic encephalopathy, and hepatocellular carcinoma. The structure of the program includes a mix of didactic presentations and case-based presentations delivered by expert faculty. This program is designed for gastroenterologists, primary care physicians, nurses, physician assistants, and nurse practitioners interested in the latest information on liver diseases and state-of-the-art treatment of these illnesses. 10 WESTERN REGIONAL POSTGRADUATE COURSE The field of gastroenterology continues to experience introductions of new and novel diagnostic techniques and therapeutic options affecting numerous areas of gastrointestinal disease management and patient care. This program is designed to explore those areas and will address management updates in a variety of GI and hepatic areas. The program will explore common questions on bloating, heartburn, constipation, fecal incontinence, traveler s diarrhea, and cannabis, as well as state-of-the-art updates on IBD, FMT, obesity, pancreatic cancer, endoscopy, and practice management and medicine in general. The structure of the program includes a mix of didactic presentations delivered by expert faculty, question and answer periods, smaller afternoon general sessions, and non-cme hands-on workshop sessions. This program is designed for gastroenterologists, primary care physicians, nurses, physician assistants, and nurse practitioners interested in the latest information on diagnostic GI and liver diseases and state-of-the-art treatment of these illnesses. ACCREDITATION / CME / MOC The American College of Gastroenterology is accredited by the American Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. ACG S HEPATOLOGY SCHOOL The American College of Gastroenterology designates this live activity for a maximum of 8 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 8 MOC points in the ABIM s MOC program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. WESTERN REGIONAL POSTGRADUATE COURSE The American College of Gastroenterology designates this live activity for a maximum of 12.25 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 12.25 MOC points in the ABIM s MOC program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

REGISTER EARLY AND SAVE! MEETINGS.GI.ORG REGISTRATION NEW EARLY BIRD RATES! There are separate registration fees for ACG s Hepatology School and the Western Regional Postgraduate Course. The registration fee for each course includes admission to sessions, continental breakfasts, lunch on Friday for ACG s Hepatology School attendees, lunch on Saturday for Western Regional Postgraduate Course attendees, and refreshment breaks. ACG S HEPATOLOGY SCHOOL Early Bird Reg. (by 2/24) (after 2/24) Member Type $125 $200 ACG Physician Member/Fellow $125 $200 ACG Trainee/Candidate/ Resident Member $125 $200 ACG NP/PA/Allied Health Member $175 $250 Non-member Physician/PharmD/PhD/Guest $175 $250 Non-member Trainee/Resident $175 $250 Non-member NP/PA/Allied Health WESTERN REGIONAL POSTGRADUATE COURSE Early Bird Reg. (by 2/24) (after 2/24) Member Type $449 $499 ACG Physician Member/Fellow $179 $254 ACG Trainee/Candidate/ Resident Member $289 $364 ACG NP/PA/Allied Health Member $549 $599 Non-member Physician/PharmD/PhD/Guest $229 $304 Non-member Trainee/Resident $289 $424 Non-member NP/PA/Allied Health Full refund of registration fees will be given, less a $25 administrative fee, if written notice of cancellation is received by ACG by February 24, 2017. No refunds will be given after this date. MOBILE APP INFORMATION Included with your registration is complimentary access to the course presentations via the ACG Mobile App. The App can be used to download faculty presentations onto tablets, mobile devices, and laptops, and provides note-taking/highlighting capabilities. Take notes at the event and review when you get home. Presentations will also be available online in PDF format. You will have access prior to the programs to download or print the slides. (NOTE: A printed syllabus will not be available.) ACCOMMODATIONS The program will be held at The Cosmopolitan of Las Vegas, centrally located on the Las Vegas Strip. Enjoy the Vegas nightlife and entertainment when you attend the course. To make reservations, please call The Cosmopolitan at 855-435-0005 or 702-698-7575, or make your reservation online at https://aws.passkey.com/go/samcg7. Special meeting rates per night are $239 single/double plus resort fee ($20) and tax. Additional fees of service charge and tax will apply. The hotel accepts MasterCard, VISA, American Express, Discover and Diner s Club. Reservations must be made by February 24, 2017. There are a limited number of rooms available at the meeting rate. There is no guarantee that rooms will be available up to the deadline, and there is no guarantee that rooms will be available at the ACG meeting rate. Rates quoted are on a space-available basis only. Cancellations made within 72 hours of arrival will be penalized for one night s room and tax. Cancellations made prior to 72 hours will not be penalized. Check-in is at 3:00 pm. Check-out is at 11:00 am. The Cosmopolitan is located at 3708 Las Vegas Boulevard South, Las Vegas, Nevada 89109. MORE INFORMATION For more information about the meeting, contact ACG at education@gi.org. Americans with Disabilities Act (ADA): Attendees of these programs who need additional reasonable accommodations or who have special needs (including dietary needs) should contact the ACG office by email at registration@gi.org no later than February 24, 2017. REGISTER BY FEBRUARY 24, 2017 AND SAVE! MEETINGS.GI.ORG 11

AMERICAN COLLEGE OF GASTROENTEROLOGY 6400 Goldsboro Road, Suite 200 Bethesda, MD 20817 2017 ACG S HEPATOLOGY SCHOOL & WESTERN REGIONAL POSTGRADUATE COURSE THE COSMOPOLITAN OF LAS VEGAS MARCH 10 12, 2017 REGISTER EARLY AND SAVE! meetings.gi.org ATTENDEES: USE THE ACG MOBILE APP TO ACCESS FACULTY PRESENTATIONS