Nicholas W. Simon Ph.D. Curriculum Vitae

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Curriculum Vitae Nicholas W. Simon Ph.D. Office Address Department of Psychology University of Memphis 400 Innovation Drive Memphis TN 38152 Office: 416 Psychology Building Phone: (901) 678-4986 Email: nwsimon@memphis.edu Education 2004-10 Ph.D., Department of Psychology/Behavioral and Cellular Neuroscience, Texas A&M University 2002-04 M.S., Department of Experimental Psychology, Western Illinois University 1996-00 B.A., Major: Biology, Minor: Psychology, Carthage College (Kenosha, WI) Professional Research Experience 2016-current Assistant Professor, University of Memphis, Department of Psychology 2015-2016 Research Assistant Professor, University of Pittsburgh, Department of Neuroscience 2010-15 Post-Doctoral Fellow, University of Pittsburgh, Department of Neuroscience Laboratory of Dr. Bita Moghaddam 2004-10 Graduate Research Assistant, Texas A&M Psychology Department Laboratory of Dr. Barry Setlow 2002-04 Graduate Research Assistant, Western Illinois University Laboratory of Dr. Matthew Blankenship 2000 Undergraduate Research Fellow, Carthage College Laboratory of Dr. Daniel Miller Grants / Funding Current Funding: 2017-18 College of Arts and Sciences Faculty Research Grant; Modeling addiction vulnerability with a rat decision-making task ; Nicholas Simon, PI ($10,000) 2016-18 Brain and Behavior Research Foundation Young Investigator Grant (NARSAD); Dissecting the neural circuitry of motivation symptoms related to mood disorders ; Nicholas Simon, PI ($70,000)

Previous Funding: 2014-16 Center for the Evaluation of Nicotine in Cigarettes (CENIC) Pilot Project Fund; Neuronal correlates of nicotine reduction in a rodent model of extended nicotine exposure ; Nicholas Simon, PI ($50,000) 2013-15 F32 Ruth L. Kirschstein Postdoctoral NRSA, NIDA; Neural Processing in Behaving Adolescent Rodents. 2011-13 T32 Training grant, University of Pittsburgh Department of Psychiatry, NIDA 2008-10 F31 Ruth L. Kirschstein Predoctoral NRSA, NIDA; Long-term cocaine effects on impulsive choice and orbitofrontal cortex activity. Honors and Awards 2014 Schizophrenia International Schizophrenia Research Society (SIRS) Post Doctorate Travel Award 2013 American College of Neuropsychopharmacology (ACNP) Early Career Travel Award 2011 College for Problems in Drug Dependence (CPDD) Early Career Investigator Award 2010 Association of Former Students at Texas A&M University Distinguished Graduate Student Award for Excellence in Research 2009 Texas A&M Chapter Society for Neuroscience (SFN) Poster Competition, Second place 2009 International Society of Research on Impulsivity and Impulse Control Disorders (ISRI) Travel Award 2008 SFN Chapters Graduate Student Travel Award 2008 Selected to participate in National Institute of Drug Abuse (NIDA) Early Career Investigators Poster Session by American Psychology Association (APA) 2008 Travel Award, Division of Basic Neuroscience and Behavioral Research at NIDA 2007 Travel Fellowship, New York Academy of Sciences 2006 Poster Award for Excellence in Presentation and Scientific Content, Eighth Conference on the Neurobiology of Learning and Memory, University of California, Irvine 2005 Office of Graduate Studies Travel Award, Texas A&M University 2004 Department of Psychology Travel Award, Western Illinois University 2000 Summer Undergraduate Research Experience (SURE) Fellow, Carthage College Formal Presentations 2017 Invited Speaker at Neuroscience Institute Seminar Series, University of Tennessee Health Science Center. 2014 Presenter in mini-panel: Is the Associative Striatum a Locus of Vulnerability for Transition to psychosis? 53 rd annual ACNP Meeting. 2014 Presenter in Nanosymposium: Human Reinforcement Learning: Development and Aging. SFN Conference, Washington DC.

2014 Presenter in Symposium: Reward processing, cognition, and perception during adolescent brain development and vulnerability to psychosis Schizophrenia International Research Society Conference, Florence, Italy 2013 Speaker, Department of Neuroscience Research Day, University of Pittsburgh 2011 Invited Lecture, Department of Psychology Symposium Series Western Illinois University 2009 Featured Speaker, Faculty of Neuroscience Texas A&M University and Health Science Center Neuroscience Symposium 2006 Panel Fellow, Linking Affect to Action: Critical Contribution of the Orbitofrontal Cortex, Session VII: Orbitofrontal Cortex, Mental Health, and Aging Peer-Reviewed Publications Google Scholar H-index: 13; i-10 index: 15 1. Wood J., Simon, N.W., Koerner, S., Kass, R.E., & Moghaddam, B. (in press). Networks of VTA neurons encode real-time information about uncertain numbers of actions executed to earn a reward. Frontiers in Behavioral Neuroscience. 2. Bueno Junior, L.S., Simon, N.W., Wegener, M.A., & Moghaddam, B. (2017). Repeated nicotine strengthens gamma oscillations in the prefrontal cortex and improves visual attention. Neuropsychopharmacology, 42, 1590-98. 3. Simon, N.W. & Moghaddam, B (2017). Methylphenidate has nonlinear dose effects on cued response inhibition in adults but not adolescents. Brain Research, 1654, 171-176. 4. Kim, Y.B., Simon, N.W., Wood, J., & Moghaddam, B. (2016). Reward anticipation is encoded differently by adolescent VTA neurons. Biological Psychiatry, 79, 878-886. 5. Simon, N.W., Wood, J, & Moghaddam, B. (2015). Action-outcome relationships are represented differently by medial prefrontal and orbitofrontal cortex neurons during action execution. Journal of Neurophysiology, 114, 3374-85. 6. Simon, N.W. & Moghaddam, B. (2015). Reward processing in adolescent rodents. Developmental Cognitive Neuroscience, 11, 145-54. 7. Simon, N.W., Gregory, T.A., Wood, J., & Moghaddam, B. (2013). Differences in response initiation and behavioral flexibility between adolescent and adult rats. Behavioral Neuroscience, 127, 23-32. 8. Simon, N.W., Beas, B.S., Montgomery, K.S., Gilbert, R.J., Haberman, R.P., Bizon, J.L., & Setlow, B. (2013). Prefrontal cortical-striatal dopamine receptor mrna predicts distinct forms of impulsivity. European Journal of Neuroscience, 37, 1779-88. 9. Simon N.W. & Setlow, B. (2012). Modeling risky decision-making in rodents. Methods of Molecular Biology, 829, 165-75. 10. Gilbert, R.J., Mitchell, M.R., Simon, N.W., Banuelos, C., Setlow, B., & Bizon, J.L. (2011). Risk, reward, and decision-making in a rodent model of cognitive aging. Frontiers in Decision Neuroscience, 5, 144. 11. Simon N.W., Montgomery, K.S., Beas, B.S., Mitchell, M.R., LaSarge, C.L., Mendez, I.A., Bañuelos, C., Vokes, C.M., Taylor, A.B., Haberman, R.P., Bizon, J.L., & Setlow, B. (2011). Dopaminergic modulation of risky decision-making. The Journal of Neuroscience, 31, 17460-70.

12. Mitchell M.R., Vokes, C.M., Blankenship, A.L., Simon, N.W., Setlow, B. (2011). Effects of acute administration of nicotine, amphetamine, diazepam, morphine, and ethanol on risky decision-making in rats. Psychopharmacology, 218, 703-12. 13. Mendez, I.A., Simon, N.W., Hart, N., Mitchell, M.R., Nation, J.R., Wellman, P.J., & Setlow, B. (2010). Selfadministered cocaine causes lasting increases in impulsive choice in a delay-discounting task. Behavioral Neuroscience, 124, 470-7. 14. Simon, N.W., LaSarge, C.L., Williams, M.T., Montgomery, K.S., Mendez, I.A., Setlow, B, & Bizon, J.L. (2010). Good things come to those who wait: Impulsive choice is attenuated in aged Fischer 344 rats. Neurobiology of Aging, 31, 853-62. 15. Setlow, B., Mendez, I.A., Mitchell, M.R., & Simon, N.W. (2009). The effects of chronic administration of drugs of abuse on discounting of delayed rewards (impulsive choice) in animal models. Behavioural Pharmacology, 20, 380-389. 16. Simon, N.W., Gilbert, R.J., Mayse, J.D., & Setlow, B. (2009). Balancing risk and reward: A rat model of risky decision-making. Neuropsychopharmacology, 34, 2208-2217. 17. Simon, N.W., Mendez, I.A., & Setlow, B. (2009). Prior amphetamine exposure alters approach strategy during Pavlovian conditioning. Psychopharmacology, 202, 699-709. 18. Mendez, I.A., Montgomery, K.S., LaSarge, C.L., Simon, N.W., Bizon, J.L., & Setlow, B. (2008). Long-term deficits in spatial learning produced by cocaine exposure. Neurobiology of Learning and Memory, 89, 185-191. 19. Simon, N.W., Mendez, I.A., & Setlow, B. (2007). Cocaine exposure causes long-term increases in impulsive choice behavior. Behavioral Neuroscience, 121, 543-549. 20. Simon, N.W. & Setlow, B. (2006). Post-training amphetamine enhances memory consolidation in appetitive Pavlovian conditioning: Implications for drug addiction. Neurobiology of Learning and Memory, 86, 305-310. Conference Rapporteur Publications 1. Abatomi, O, Amato, D Simon, N., et al. (2014). The 4 th Schizophrenia International Research Society Conference, 5-9 April 2014, Florence Italy: A summary of topics and trends. Schizophrenia Research, 159, e1-22. Selected Conference Abstracts (of 65 total) 1. Gabriel, D, Freels, T, & Simon, N.W. (2017). Individual differences in risky decision-making predict nicotine sensitivity and other addiction-relevant behaviors. Society for Neuroscience Abstracts. 2. Freels, T, Gabriel, D, & Simon, N.W. (2017). The effects of enhanced cannabinoid signaling on risky decision-making in rodents. Society for Neuroscience Abstracts. 3. Simon, N.W., & Moghaddam, B (2016). Nicotine disengages orbitofrontal cortex during Pavlovian conditioning. Society for Neuroscience Abstracts. 4. Simon, N.W., Bueno Jr., L.S., Wegener, M.A., & Moghaddam, B. (2015). Nicotine causes parallel increases in medial prefrontal cortex gamma oscillations and visual attention. ACNP Abstracts.

5. Simon, N.W., Wood, J., & Moghaddam, B. (2013). Theta oscillations in rat prefrontal cortex are modulated by actions and outcomes. Society for Neuroscience Abstracts. 6. Simon, N.W., Wood, J.T., & Moghaddam, B. (2011). Prefrontal cortical activity reflects shifts in actionoutcome value. Society for Neuroscience Abstracts. 7. Simon, N.W., Montgomery, K.S., Beas, B.S., LaSarge, C.L., Haberman, R.P., Bizon, J.L., & Setlow, B. (2010). Dopamine receptor modulation of risky decision-making. Society for Neuroscience Abstracts, Selected for F1000 Posters. 8. Simon, N.W., Gilbert, R.J., Mayse, J.D., & Setlow, B. (2008). A rat model of risky decision-making: the role of dopamine in balancing risk and reward. Society for Neuroscience Abstracts. 9. Simon, N.W., LaSarge, C.L., Williams, M.T., Montgomery, K.S., Mendez, I.A., Setlow, B., & Bizon, J.L. (2008). Impulsive choice is attenuated with age in Fischer 344 rats. FENS abstract vol. 4 015 27. 10. Simon, N.W., Mendez, I.A., & Setlow, B. (2007). Prior amphetamine exposure alters approach strategy during Pavlovian conditioning. Linking Affect to Action: Critical Contribution of the Orbitofrontal Cortex Abstracts. 11. Simon, N.W. & Setlow, B. (2006). Effects of post-training d-amphetamine on appetitive Pavlovian conditioning. Eighth Conference on the Neurobiology of Learning and Memory Abstracts. Graduate Student Award for Excellence in Presentation and Scientific Content. Journal Article Reviews Ad Hoc Reviewer: Neuropsychopharmacology Cerebral Cortex Journal of Neurophysiology Neuropharmacology Psychopharmacology Neurobiology of Aging International Journal of Neuropsychopharmacology Neuroscience Behavioral Neuroscience Behavioural Brain Research Journal of Psychopharmacology PLOS One Pharmacology, Biochemistry, and Behavior Scientific Reports Frontiers in Behavioral Neuroscience Psychoneuroendocrinology Behavioural Processes Behavioral and Brain Functions Physiology and Behavior Teaching Experience Spring 2017 Professor, PSYC 7705/8705 Neuropsychopharmacology

Department of Psychology, University of Memphis Teaching Evaluation (overall mean): 4.96/5 (5=excellent, 1= ineffective) Professor, PSYC 3306; Teaching Evaluation: 4.76/5 Fall 2016 Professor, PSYC 3306, Physiological Psychology Department of Psychology, University of Memphis Teaching Evaluation: 4.6/5 Summer 2015 Instructor, NROSCI 0081, Drugs and Behavior Department of Neuroscience, University of Pittsburgh Teaching Evaluation: 4.6/5 Graduate Student Mentorship Principle Mentor: Daniel Gabriel, Masters Student (2016-17); PhD student (2017-current) Anna Vongphrachanh, PhD student (2017-current) Co-mentor: Timothy Freels, PhD student (2016-current) Student Committees Graduate Students 2017-current 2017-current 2016-current Lauren Schaefer, Clinical Psychology Doctoral Student, University of Memphis Kathyrn Soltis, Clinical Psychology Doctoral Student, University of Memphis Samuel Acuff, Clinical Psychology Masters Student, University of Memphis Undergraduate Students 2017 Jasric Bland, Behavioral Neuroscience Honors Thesis, University of Memphis 2016 Katie Matney, Behavioral Neuroscience Honors Thesis, University of Memphis

References Bita Moghaddam, PhD Professor and Chair of Behavioral Neuroscience Department Oregon Health and Science Center bita@ohsu.edu Barry Setlow, PhD Professor, Department of Psychiatry University of Florida setlow@ufl.edu Jennifer Bizon, PhD Professor, Department of Neuroscience University of Florida bizonj@ufl.edu Frank Andrasik, PhD Distinguished Professor and Chair of Psychology Department University of Memphis fndrasik@memphis.edu