Name Date Class. Interphase. (1) The. grows. DNA is duplicated.

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Concept Mapping The Cell Cycle Complete the cycle map about the cell cycle. These terms may be used more than once: cell, cytoplasm, metaphase, nuclear membrane, nucleoli, poles. (1) The Interphase grows. DNA is duplicated. Cytokinesis (6) divides. Two cells are formed. Prophase Chromosomes condense. (2) The and nucleolus disappear. Spindle apparatus forms. Telophase Chromosomes arrive at poles. Nuclear membranes and (3) (5) reappear. Sister chromatids line up at equator. Chromosomes decondense. Anaphase Chromatids are pulled apart toward (4). 124 Cellular Reproduction Unit 2

Section 1: Cellular Growth In your textbook, read about cell size limitations. List two alternative futures for cells when they reach their size limitations. 1. 2. In your textbook, read about the cell cycle. Draw the cell cycle in the space below. Include the following labels: cytokinesis, G 1, G 2, interphase, mitosis, S. 3. Match the definition in Column A with the term in Column B. Column A 4. stage in which the cell divides into two daughter cells with identical nuclei 5. substage of interphase immediately after a cell divides 6. substage of interphase in which the cell copies its DNA in preparation for cell division 7. stage in which the cell s nuclear material divides and separates Column B A. S phase B. cytokinesis C. G 1 D. G 2 E. interphase 8. main stage in which the cell grows, carries out normal functions, and duplicates its DNA 9. substage in which the cell prepares for nuclear division and a protein that makes microtubles for cell division is synthesized F. mitosis Unit 2 Cellular Reproduction 125

Section 2: Mitosis and Cytokinesis In your textbook, read about the stages of mitosis. For each statement below, write true or false. 1. The nuclear membrane disintegrates during prophase. 2. Microtubules move chromatids to the poles of the cell during anaphase. 3. Chromosomes reach the poles of the cell during metaphase. 4. The cell s chromatin condenses into chromosomes during prophase. 5. The nuclear envelope re-forms during anaphase. 6. Chromosomes attach to spindle fibers and line up along the equator of the cell during metaphase. 7. The nucleus reappears during prophase. 8. Centrioles migrate to the poles of the cell during telophase. 9. Chromatids are pulled apart during anaphase. 10. The first stage of mitosis is telophase. 11. The chromosomes decondense or unwind during telophase. 12. The shortest stage of mitosis is metaphase. Label the diagram of the stages of mitosis using lines 13 16. Use these choices: anaphase metaphase prophase telophase Label the diagrams above using lines 17 20. Use these choices: centrioles centromere sister chromatids spindle fibers 126 Cellular Reproduction Unit 2

, Section 2: Mitosis and Cytokinesis continued In your textbook, read about cytokinesis. Animal cell Plant cells Refer to the diagrams above. Respond to each statement. 21. Discuss the role of microfilaments in cytokinesis. 22. Summarize cell division in prokaryotes. Draw the formation of two genetically identical cells in plants in the space below. Include the following labels: cell plate, identical daughter cells, new cell wall. 23. Unit 2 Cellular Reproduction 127

Section 3: Cell Cycle Regulation In your textbook, read about the abnormal cell cycle and cancer. Complete the graphic organizer about the causes and prevention of cancer. These terms may be used more than once: carcinogens, cell cycle, cells, DNA damage, genetic changes, spindle fiber failure, the Sun s ultraviolet rays, tobacco. Cancer is the uncontrolled growth and division of 1. that is often prevented by that is caused by cell-cycle checkpoints that monitor for unrepaired 2. exposure to 3. or 4. 5. and stop the 6. before cytokinesis Complete the table by checking the correct column for each description. Description Apoptosis Stem Cells 9. After a sperm fertilizes an egg, the resulting mass of cells divides until there are about 100 to 150 cells. 10. Some cells go through a programmed death. 11. Embryonic cells shrivel and die, resulting in the formation of fingers and toes. 12. Unspecialized cells are either embryonic or adult. 13. This event occurs in cells that are damaged beyond repair. such as 7. 8. excessive X rays 128 Cellular Reproduction Unit 2