IMAGE-GUIDED SPINE SURGERY

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SPINE NAVIGATION

IMAGE-GUIDED SPINE SURGERY CONFIDENCE AND ACCURACY Brainlab Spinal Navigation combines state-of-the-art touch screen based image control with best-in-class registration methods for image-guided surgery. As an open navigation platform, Brainlab Spinal Navigation enables accurate pedicle screw placement as well as drastic reduction of X-Ray exposure to both the surgical team and the patient. Navigation of implants and instruments is possible in 2D images, 3D fluoroscopy scans, MR or CT datasets in all stages of surgery from incision planning to implant placement. The indication range covers pedicle screw placement in any area of the spine, placement of C1-C2 screws, complex deformity correction, tumor surgery and surgical planning. 2 of 20

MULTIPLE INDICATIONS GREATER VISUALIZATION The indication range of Brainlab Spinal Navigation spans cervical and high thoracic dorsal instrumentations to routine lower lumbar surgery, tumor treatment and deformity surgery planning and visualization. Navigation is possible in 2D images as well as 3D scans from various scanners; both pre- and intraoperative CT images can be registered. Pre- and manually calibrated instruments can be utilized, as well as instruments from any other implant system which are integrated with universal adapter clamps. Depending on the surgical case, additional features such as Co-Registration, CT-Fluoro Matching or CT/MR-Fusion provide a wide range of image information. 3 of 20

Brainlab Spinal Navigation assists in the safe placement of implants, especially in anatomically critical areas. Real time visualization of instruments leads to greater accuracy of implant placement while sparing X-Ray exposure.

In tumor surgery, critical information derived from CT and MR images can be used simultaneously by fusing these images. Additional visualized safety zones and intersections of tumor and bone objects result in more precise resection of osteosarcoma and a reduction of soft-tissue trauma.

For easy, confident pedicle screw placement in minimally invasive cases, 2D fluoroscopic images can be registered automatically with xspot; 3D C-arm scans even without additional imaging. Incisions and trajectories can be planned accurately with any instrument at skin level.

The combination of pre-planning and quick registration of adjacent levels allows the support of complex procedures like deformity corrections. The improved orientation of navigation and enhanced information from planning is especially valuable with deformed anatomy, resulting in less soft tissue trauma and greater efficiency.

SIMPLE REGISTRATION PRACTICAL SIMPLICITY Navigation can be performed in any common image format from 2D and 3D images to MR, CT and robotic iangio 3D scans, regardless of pre- or intraoperative image acquisition. After a quick automatic image registration or point based registration, navigation can begin. Attached to the pointer, SmartClip enables remote control of the application. Automatic Image Registration with Airo Mobile Intraoperative CT 8 of 20

Minimally invasive 2D Fluoro Registration is performed more easily than ever with xspot.

With Fluoro 3D Registration, 3D C-arm scans are registered automatically and less invasively within seconds.

For open surgeries, registration can be performed manually on the bone surface. Surface Matching is a fast manual registration method with an auto-correcting algorithm. Paired Point Matching is done with pre-or intraoperative planning of surface points andregistration of other anatomical structures. This applies especially to deteriorated bony conditions and non-spinal regions.

With Airo Mobile Intraoperative CT and Automatic Image Registration scans are registered and transferred automatically to the navigation system for minimally invasive and open procedures.

FUSION AND CO-REGISTRATION IMAGE UNITY To gain even more insight for individual cases Brainlab Spinal Navigation offers additional features. CT-Fluoro Matching allows for the registration of pre-operative CT scans with two conventional C-arm images for minimally invasive procedures. To drastically enhance image quality, Co-Registration allows co-registering of pre-op CT scans with automatically registered Fluoro 3D data, for example, in cases involving obese patients. For additional soft tissue information, for instance, in tumor treatment, Fusion brings full pre-operative MR information together with a registered CT scan. CT/MR-Fusion 13 of 20

INSTRUMENT INTEGRATION SEAMLESS WORKFLOWS In addition to a range of Brainlab instruments, cooperations with DePuy Synthes and other selected 3rd party manufacturers also provide navigation-ready integrated instruments. Moreover, the open platform principle of Brainlab Spinal Navigation enables any instrument to be manually calibrated for navigation by attaching adapter clamps. Pre- or manually calibrated instruments can be integrated into Navigation for smooth and seamless workflows. Follow standard clinical workflow Navigate up to eight instruments simultaneously without the need for re-selection Visualize pre-calibrated instruments in 3D geometry Integrate any instrument and implant system with universal adapter clamps 14 of 20

INSTRUMENT INTEGRATION DEPUY SYNTHES Integrated Viper2 // Expedium instruments Thoraco-lumbar posterior stabilization Pre-calibrated cannulated and non-cannulated awls, probes, taps Manually calibrated cannulated and non-cannulated screwdrivers DePuy Synthes - Viper2 // Expedium 15 of 20

INSTRUMENT INTEGRATION AESCULAP Integrated S 4 Cervical instruments Cervical-thoracic posterior stabilization Pre-calibrated guide sleeves, drill guide & tap Manually calibrated screwdriver Aesculap S 4 Cervical 16 of 20

INSTRUMENT INTEGRATION ULRICH MEDICAL Integrated tangors // neon instruments Cervical and thoraco-lumbar posterior stabilization tangors: pre-calibrated instrumentation for open thoraco-lumbar posterior stabilization neon: pre-calibrated instruments for cervical posterior stabilization ulrich medical - tangors // neon 17 of 20

INSTRUMENT INTEGRATION BRAINLAB Integrated universal spinal instruments Pre-calibrated awls and probes for thoraco-lumbar posterior stabilization Pre-calibrated guide tubes and drill bits for navigated drilling Manually calibrated chisels for navigated osteotomies Brainlab Spinal Instruments 18 of 20

INTELLIGENT PLATFORMS TOUCH-BASED COMMAND AND CONTROL 19 of 20

brainlab.com 2016 Brainlab AG. ST_BR_EN_Spine_Image Guided Surgery_Oct13_Rev3