Colorectal Surgery Benign Anal Conditions...

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Colorectal Surgery Benign Anal Conditions... Lee Dvorkin Consultant General, Colorectal & Laparoscopic Surgeon, NMUH Clinical Lead for General Surgery, NMH Senior Clinical Lecturer, UCLH Associate Professor of Surgery, SGU

The next 45 minutes... 7 common conditions Fissure in ano Haemorrhoids Fistulae Pilonidal sinus Pruritus ani Rectal prolapse Faecal Incontinence

Anal fissure Ischaemic ulcer Posterior midline anal canal

Aetiology Constipation Postpartum females (anterior fissure) Crohn s (multiple fissures) Internal anal sphincter spasm

Presentation Severe pain on defaecation Blood pr

Management (Medical) Dietary (Movicol) GTN (0.2 0.4 %) 38 % headaches Diltiazem (2 %) Botulinum toxin A

Surgery... Caution!

Surgery Anal stretch (Incontinence > 30 %) Lateral internal sphincterotomy Morbidity 10-20 % flatus incontinence 10-20 % mucus discharge Low recurrence

Caution Post partum women & women with low pressure fissures Advancement flap as opposed to spincterotomy ( to avoid incontinence)

Haemorrhoids Common 50 % population > 50 years Vascular cushions (functional importance in maintenance of continence)

XXXX Piles

Piles?

Haemorrhoids aetiology Straining at stool Prolonged perineal descent (sitting on the loo) Familial tendency Poor connective tissue support

Presentation PR bleed Prolapse Discomfort Pain suggests thrombosis Bleeding > 35 (exclude Ca)

Treatment Depends on severity and symptoms First degree: doesn t descend, may bleed Second degree: protrudes below dentate line, return spontaneously Third degree: requires manual reduction Forth degree: irreducible

Management Patient education Dietary manipulation Avoid straining Avoid reading on the loo!

Treatment Sclerotherapy Banding Haemorrhoidectomy Stapled haemorrhoidectomy (PPH) THD / HALO

OPD management: Sclerotherapy Oily Phenol 5% Nut allergy avoid anterior injection in males (prostatitis) Only for small piles

OPD management: Banding More effective than sclerotherapy Discomfort 20 mins after procedure Lifts piles

Haemorrhoidectomy Conventional Milligan Morgan Stapled haemorrhoidectomy Haemorrhoidal artery ligation (HALO)

Haemorrhoidectomy consent Pain Open wounds Flatus incontinence Anal stenosis Post op laxatives & Metronidazole

A common question... When do I refer PR bleeding and piles? Don t assume PR bleeding is piles esp in over 40 s Have a low threshold for endoscopic examination Piles are completely benign and don t need treatment unless patients quality of life is affected

A plee... No FOB s No CEA

Fistula in ano

Treatment options Conservative Lay open: the only cure for a fistula Seton Fibrin glue Advancement flap LIFT

Diagnosis...??

Pilonidal sinus Hair within perinatal cleft Umbilicus Webshaft of finger spaces Hirsuit

Presentation Asymptomatic Recurrent discharge and pain Abscess

Management Minimalistic approach Regular shaving Acute drainage Lateral approach (away from midline) Karydakis / Bascombe Rhomboid flap

Rhomboid flap

Pruritus ani Benign: piles, fistulae, polyp Dermatological Infection Neoplasia

Management Attempt to identify precipitating cause Avoid scratching Avoid excessive cleaning (bidet ideal) Avoid perfumed soap Avoid toilet paper

Management Barrier creams in combination with temporary steroid use Epaderm & Betnovate (max use 10 days) EUA

Rectal prolapse

Management Conservative (not a good option usually) Abdominal approach (rectopexy + resection) Laparotomy Constipation Low recurrence Laparoscopic rectopexy Perineal approach (Delormes / Altmeier) Reduced morbidity Increased recurrence rate (30 %)

Faecal Incontinence Distressing & socially incapacitating condition True prevalence remains unknown 3 8% of the population increasing in the elderly

Continence mechanisms Anatomy Resting tone: 55% IAS 30% EAS 15% haemorrhoidal plexuses

Frequency (%) Faecal Incontinence: Referral pattern n = 629 Ratio F:M = 3:1 80 70 60 50 40 30 20 10 0 Female Male

FI: Symptoms Urge Incontinence occurring with the patient s awareness, against their will because of lack of voluntary control two-minute warning Passive Without the patient s knowledge Post-defaecation leakage

FI: aetiology Trauma Obstetric injury Surgery Accidental Colorectal disease Rectal prolapse IBD Tumours Neurological Cerebral/spinal/peripheral Congenital Spina bifida Miscellaneous Behavioural, impaction

Frequency (%) n = 439 Obstetric Factors 80 70 60 50 40 30 20 10 0 Overall Tear Episiotomy Forceps Ventouse Hysterectomy

Frequency (%) n = 154 Anal Surgery (Males) 50 45 40 35 30 25 20 15 10 5 0 Overall Piles Banding Fistula -otomy Stretch

Treatment Exclude serious pathology Multimodal investigation if severe U/S Pressure testing Evacuation Proctography

Treatment Avoid caffeine/spicy foods Imodium / Codeine Pads Anal plug (Peristeen) Biofeedback Surgical repair Artificial sphincter Stoma SNS/PNS

Sacral Nerve Stimulation Matzel in 1995 for FI. Stimulation of S3 neuromodulation effect on ascending pathways, local autonomic system Locally (sphincter pressures, rectal sensation) Distant (gut motility, sensory cortex) 2 stage procedure Trial period 3 weeks Permanent implant

Indications Faecal Incontinence NICE approved 2004 50% virtually continent, 30% of the rest will have a sig reduction in FI No trial yet comparing to sphincter repair

Expensive SNS: Problems Test box 200, Lead 2000, Battery 8000 Post operative problems Infection, nerve damage, battery lasts 6-8 years Loss of efficacy over time Requires regular re-programming Pregnancy Must be switched off during pregnancy c-section to avoid lead displacement

Posterior Tibial Nerve Stimulation 2003 used for FI Remote neuromodulation of sacral plexus via the posterior tibial nerve Achieved by Percutaneous transcutaneous

PTNS- Indications Just FI, so far 11 studies, most demonstrated sig improvement Given as a 1-2 month course Percutaneous more efficacious than transcutaneous Therapeutic effect that can persist for several months after treatment Large multicenter study under way comparing PTNS with SNS

PTNS- Problems Cheap equipment costs Needles 200 Pads 3 Stimulator boxes 80 Labour intensive Percutaneous PTNS requires practitioner support But transcutaneous can be self-administered

The past 45 mins Proctology Demonstrated array of pathologies seen Highlighted areas where primary care can take a bigger role

Questions?

Diverticular Disease Lee Dvorkin

Right sided in Orient Left sided in West 75% of over 70 yrs Only 10-30% cause symptoms Dilemma comes as to when, how and who to operate on

Don t assume change in bowel habit is diverticular disease

Aetiology Poor dietary fibre Hyperelasytosis and altered collagen structure with ageing Narrow sigmoid leads to high intraluminal pressures with mucosa protrusion at anatomical weak points

Complications Pain Diverticultis Fistula Bleeding Stricture Perforation

Presentation Elective Lower abdo pain Altered bowel habit distension Treatment Exclude cancer Reassure Increase fibre Surgery: beware concurrent IBS

Emergency Acute diverticulitis Fistula LIF pain Change in bowel habit Peritonism Sepsis Any adjacent organ Colovesical & colovaginal most common ddx: Crohn s, cancer

Emergency Abscess Bleeding Lower abdo pain/mass Systemic sepsis Painless & profuse Colour depends on site and speed

Emergency Obstruction Fibrosis stricture from longstanding sigmoid diverticular disease Presents exactly as LBO due to cancer Often cant tell until after resection

Investigation Depends on clinical presentation Most managed as outpatient with colonoscopy to confirm diagnosis Inpatients have variety of investigations CT Contrast enema Angiogram

Management Elective Recurrent persistent symptoms Development of a complication Evidence suggests that first attack often the worst and only a minority continue with problems Fistulae often too morbid to treat conservatively Emergency Severe sepsis not controlled with antibiotics Generalised peritonitis that fails to respond to treatment Torrential bleeding

Surgical issues in acute setting..? When to operate? ongoing clinical assessment When to resect bowel? lavage?? When to anastamose? avoiding anastamosis not always the easy option

Subsequent elective surgery Limited evidence to inform practice Ambrosetti et al... 14% recurrence after mild first attack 39% after a severe attack Higher chance recurrence in young 1 admission with severe attack in young 2 admissions Suspicion of malignancy

Summary Sigmoid diverticular disease is common Admission is uncommon CT best investigation Urgent surgery needed in <20% Laparoscopic lavage should be considered as should primary anastamosis Offer elective surgery to young symptomatic patients