PATIENT CARE PLAN FOR CARE OF PERIPHERAL MIDLINE. Manufacturers specific recommendations should be noted and adhered to by individual practitioners.

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PATIENT CARE PLAN FOR CARE OF PERIPHERAL MIDLINE The care plan is designed to be used in conjunction with CINS Guidelines for vascular devices. Manufacturers specific recommendations should be noted and adhered to by individual practitioners. Patient addressograph label / patient name Review Dates: Date Comments REASON FOR INSERTION DEVICE TYPE DATE OF INSERTION Named Nurse or Advisor details. Issue Date: 26 th July 2012 Page: Page 1 of 12 Filename: FNUAMANMI Issue No: 2.0

Care and Maintenance of a Peripheral Midline Catheter (PM1) EXIT DRESSING CHANGE (Weekly) Action Equipment required Dressing Pack containing sterile towel and Gloves Gauze swabs x 3, Surgical tape Chlorhexidine Gluconate 2% in 70% Isopropyl alcohol swab or Chlorhexidine Gluconate 2% in 70% Isopropyl alcohol impregnated applicator Semi-Permeable transparent IV dressing Alcohol hand rub or gel Skin closure strips Skin fixation device (e.g. stat-lock) Plastic apron. Care of Exit site Dressing changes should be performed on a weekly basis or when dressing is dirty or loose. Before the procedure begins make sure that your hands are washed and dried thoroughly and that they continue to be decontaminated during the procedure. A plastic apron should be worn. Maintain aseptic technique at all times. Inspect the catheter exit site for signs of skin discolouration or signs of infection e.g. exudates from exit site. If you suspect infection please contact the hospital team who placed the catheter for advice. Refer to trouble-shooting guide. Explain the procedure to the patient. Ensure that valid consent is gained. Ensure working area is as clean as possible. Ensure all equipment is gathered before commencing the procedure and all packaging is intact and in date. Rationale To prevent infection Exit site dressings are important in preventing trauma and the extrinsic contamination of the site of entry (Jones 2004). To prevent/reduce patient anxiety Maintain safety and reassure patient. To prevent infection and catheter contamination. Issue Date: 26 th July 2012 Page: Page 2 of 12 Filename: FNUAMANMI Issue No: 2.0

Open sterile pack, allowing inner pack to fall onto the clean working area. Open out sterile pack to create a sterile field. Open remaining equipment ensuring no contamination of sterile field. Open Chlorhexidine impregnated applicator. Loosen exit site dressing. To loosen dressing lift lower end and gently ease the dressing off from the skin Dressing should be removed from the direction from the end of the line towards the exit site to prevent accidental catheter removal. Be aware that fixation device may come off with the dressing, so care should be taken to prevent migration. Aseptically remove the dressing. Wash hands and put on sterile gloves Place sterile towel as near as possible to the catheter. Clean around the catheter and exit site with Chlorhexidine Gluconate 2% in 70% Isopropyl alcohol impregnated applicator. The solution should be applied with friction but should not be too vigorous or the skin's natural defence may be destroyed. Allow to dry. Apply skin closure strips and skin fixation device, then apply highly permeable dressing to exit site. Remove the dressing towel Remove gloves. Clear away equipment. Dispose of contaminated waste as per policy. Remove apron. Decontaminate hands. Document care in patient s records making a note of the exit length. To allow for a sterile environment for accessing intravenous catheter. To reduce incidence of infection Chlorhexidine based solutions are recommended (in alcohol) as per policy (DOH 2001) To prevent accidental removal of the catheter and friction or trauma to skin surface. Alcoholic Chlorhexidine combines the benefits of rapid action and excellent residual activity (DOH 2001) Semi-permeable transparent IV dressings are well tolerated by patients (Campbell et al 1999, Treston-Aurand et al 1997, Wille 1993) and are easy to apply and remove (Wille 1997). Issue Date: 26 th July 2012 Page: Page 3 of 12 Filename: FNUAMANMI Issue No: 2.0

Peripheral Midline - 0.9% Sodium Chloride and Heparin 10 units/ml in 0.9% Sodium Chloride for injection Lock (PM2) more frequently if required Action Equipment Required Dressing Pack containing sterile towel and gloves Gauze swabs x 3 10ml syringes x 3 Chlorhexidine Gluconate 2% in 70% Isopropyl alcohol applicator or 2% Chlorhexidine in 70% Isoropyl alcohol impregnated wipe. 10ml 0.9% Sodium Chloride for injection 5mls Heparin 10units/ml in Sodium Chloride Two green needles/filter straws. Sharps container Surgical tape Alcohol hand rub Plastic apron Needle free I/V access connector change as per manufacturer s guidelines see NSF1 Cins guideline Before the procedure begins make sure that your hands are washed and dried thoroughly and that they continue to be decontaminated during the procedure. A plastic apron should be worn. Maintain aseptic technique at all times. Explain the procedure to the patient. Ensure that valid consent is gained. Inspect the catheter exit site for signs of inflammation or signs of infection e.g. exudates from exit site. If you suspect infection please contact the hospital team who placed the catheter for advice. Refer to trouble-shooting guide. Ensure working area is as clean as possible. Ensure all equipment is gathered before commencing the procedure and all packaging is intact and in date. Open sterile pack allowing inner pack to fall onto clean working area. Rationale 10 ml syringes should always be used. Smaller syringe sizes may damage the catheter (Hadaway 1998) Maintain asepsis. Reduce risk of infection. Reduce anxiety and improve patient compliance Chlorhexidine based solutions are recommended (in alcohol) dependent Issue Date: 26 th July 2012 Page: Page 4 of 12 Filename: FNUAMANMI Issue No: 2.0

Open out sterile pack to create a sterile field. Open remaining equipment ensuring no contamination of sterile field. Place 0.9% sodium chloride & Heparinised saline ampoule(s) near to the working area but not on the sterile field. Open the 2% Chlorhexidine applicator. Ensure easy access to the needle free system. Decontaminate hands. Put on sterile gloves. Connect needle/filter straw to the syringe. With a piece of sterile gauze pick up the 0.9% sodium chloride (saline) ampoule, draw up 10ml of solution. Repeat for Heparinised saline if open-ended catheter. If used dispose of the needle directly into sharps container, place the filled syringe(s) on the sterile field. Place sterile towel as near as possible to the catheter. Scrub the hub of the needle free system with 2% Chlorhexidine impregnated wipe, rubbing from the top of the needle free connector to the sides. Do this several times using different parts of the wipe, over a period of 30 seconds. Allow to dry. Attach syringe with 0.9% sodium chloride flush pull back to colour the saline with blood and inject the flush using a push/pause action, clamping as the last ml of solution is instilled into the catheter. Remove the syringe and discard. Repeat flush now using Heparinised saline NEVER FORCE THE SOLUTION INTO THE CATHETER, this can damage the catheter. Ensure that the catheter is secure and comfortable. Remove dressing towel and discard. Remove gloves. Wash hands Clear away equipment used taking care to dispose of contaminated waste as per policy. Document care in patient s records. on the availability and catheter manufacturers recommendations (DOH 2001). The pulsated flush creates turbulence within the catheter lumen, removing debris from the internal catheter wall (Goodwin & Carlson 1993, Todd 1998). Positive pressure within the lumen of the catheter should be maintained to prevent reflux of blood (INS 2000). Issue Date: 26 th July 2012 Page: Page 5 of 12 Filename: FNUAMANMI Issue No: 2.0

Peripheral Midline Administration of antibiotics/infusion/additives (PM3) Administer drugs or IV therapy as prescribed using correct diluent and rate of infusion. A midline should not be used routinely to administer chemotherapy Action Equipment Required Dressing pack containing sterile towel and gloves Gauze swabs x 3, 10ml syringes x 4 Chlorhexidine Gluconate 2% in 70% Isopropyl alcohol applicator or Chlorhexidine Gluconate 2% in 70% Isopropyl alcohol impregnated wipe 2 x 10ml 0.9% Sodium Chloride for injection NEVER USE LESS THAN A 10ML SYRINGE 5ml Heparin 10units/ml in 0.9%Sodium Chloride One green needle/ filter straw. Sharps container Surgical tape Alcohol hand rub/ gel, Antibiotics/additives/infusion as prescribed Plastic apron Rationale Before the procedure begins make sure that your hands are washed and dried thoroughly and that they continue to be decontaminated during the procedure. A plastic apron should be worn. Maintain aseptic technique at all times. Explain the procedure to the patient. Ensure that valid consent is gained. Inspect the catheter exit site for signs of skin discolouration or signs of infection e.g. exudates from exit site. If you suspect infection please contact the hospital team who placed the catheter for advice. Refer to trouble-shooting guide. Ensure working area is as clean as possible. Ensure all equipment is gathered before commencing the procedure and all packaging is intact and in date. Open sterile pack allowing inner pack to fall onto clean working area. Open out sterile pack to create a sterile field. Open remaining equipment ensuring no contamination of sterile field. Reduce the risk of infection and contamination Ensures patient compliance and reduces anxiety Maintain asepsis. Reduce the risk of infection and contamination. To avoid contamination Issue Date: 26 th July 2012 Page: Page 6 of 12 Filename: FNUAMANMI Issue No: 2.0

Place 0.9%Sodium Chloride and Heparinised saline ampoule(s) near to the working area but not on the sterile field. Open 2% Chlorhexidine wipe. Ensure easy access to the needle free system. Decontaminate hands Put on sterile gloves. Connect needle or filter straw to the syringe. Pick up a piece of sterile gauze and with it pick up the 0.9% Sodium Chloride (saline) ampoule, then draw up 10ml of solution, Repeat for second Sodium Chloride and Heparinised saline. Dispose of the needle directly into the sharps container. Place the filled syringe(s) on the sterile field. Place sterile towel as near as possible to the catheter. Scrub the hub of the needle free system with 2% Chlorhexidine impregnated wipe, rubbing from the top of the needle free connector to the sides. Do this several times using different parts of the wipe, over a period of 30 seconds. Allow to dry. Attach syringe containing the 0.9% Sodium Chloride solution to the needle free system then pull back to colour the saline with blood and then Inject the solution using a push/pause action, clamping as the last ml of solution is instilled into the catheter. Remove the syringe and discard. Blood return is not always possible with a midline NEVER FORCE THE SOLUTION INTO THE CATHETER, this can easily damage the catheter. Administer IV antibiotics/infusion/additives as prescribed. Chemotherapy should not be used via a midline. Flush catheter again using second syringe containing sodium chloride 0.9%, followed by Heparinised saline (5ml of 10units/ml) lock. Ensure that the catheter is secure and comfortable. Remove dressing towel and discard. Remove gloves. Wash hands Clear away equipment used. Dispose of contaminated waste as per organisational policy. Document care in patient s records. Creates turbulence in catheter, preventing clotting in the catheter. Maintains positive pressure and prevents backflow of blood into the catheter. Chemotherapy should not be used via a midline as it is difficult to observe for a chemotherapy extravasation. Issue Date: 26 th July 2012 Page: Page 7 of 12 Filename: FNUAMANMI Issue No: 2.0

Algorithm persistent withdrawal occlusion Blood return is absent Flush central venous catheter with 0.9% Sodium chloride in 10ml syringe using a brisk push pause technique. Check for flashback of blood Check equipment, Position, clamps, kinking. etc Ask patient to cough, deep breathe, change position, stand up or lie with foot of the bed tipped up. Ascertain possible cause of PWO Blood return is still absent Patient to receive highly Irritant drugs i.e. fluids can be infused freely by gravity but blood cannot be withdrawn from Blood return obtained - use central venous catheter as usual Exclusion Dormant line If unable to aspirate. Do not continue. Refer to Medic close line and label No Yes Consider Blood return is still absent No Proceed if happy to do as long as there are no other complications or pain Adapted from Standards for Infusion Therapy RCN (2005) SECONDARY CARE ONLY The following steps should initially be done on admission or prior to drug administration and documented in nursing care-plan so that all staff are aware that patency has been verified Step 1 Administer a 250ml normal saline challenge (unless serum sodium 120 mmol/l) via an infusion pump over 15 minutes to test for patency the infusion will probably not resolve the lack of blood return (unless the patient has a high sodium or fluid restricted go to step 2) If there have been no problems, therapy can be administered as normal. If the patient experiences ANY discomfort or there is any unexplained problems then stop and seek medical advice. OR Step 2 Instill Urokinase 5000iu in 2 mls and leave for 60 minutes. After this time withdraw the urokinase and assess the catheter again. Repeat as necessary. Issue Date: 26 th July 2012 Page: Page 8 of 12 Filename: FNUAMANMI Issue No: 2.0

Type of device Risks Actions Variations / Comments SIGN Infection due to loss of Site clean and protected with sterile skin integrity dressing as per CINS guidelines. Minimum of daily inspection of exit site for signs of inflammation or infection. Do not remove dressing unless soiled. Take swab for culture and sensitivity if indicated Check weekly or at each visit if in community setting Observe patient for signs of line infection (pyrexia/raised WCC) If clinically unstable and patient has had rigors, take blood cultures from line after an independent venous sample Assess medical condition prior to removal of line Send line tip for culture and sensitivity following removal, in community only send if line sepsis suspected Ensure administration lines in place following local policy.. Replace administration lines up to a max of 72hrs if constituted in ward environment. Label infusion lines with date for renewal. Change add-on devices at same time as administration sets or as soon as integrity is compromised. Use needle-free systems and avoid 3 way taps Midline Air embolus Use Needle-free systems Ensure air dispelled from medication/ Issue Date: 26 th July 2012 Page: Page 9 of 12 Filename: FNUAMANMI Issue No: 2.0

flushes/infusates prior to administration. Assess need for infusion pump Occlusion of lumen. Maintain patency via 0.9% Sodium chloride for injection flushes as per CINS guidelines, Pre & post drug/ infusion administration. Use heparinised saline as CINS guidelines if open ended catheter Ensure compatibility of drugs/infusates to avoid precipitation. Ensure weekly flushes when not in use. Use needle-free system according to CINS guidelines using positive pressure flush Bleeding from site / line itself. Line migration / displacement Observe for signs of bleeding from site. Apply pressure above dressing Ensure add on devices/taps securely fastened. Ensure clotting studies in acceptable range prior to removal of line. Check notes to ensure medical staff have documented line is in correct place and safe to use If line disconnected for any reason then discard Check each time line accessed for signs of line migration Anchor lines to avoid accidental displacement using fixation devices as in CINS guidelines. If in doubt do not use line and ensure patient is aware of problems which may occur. Issue Date: 26 th July 2012 Page: Page 10 of 12 Filename: FNUAMANMI Issue No: 2.0

Line in situ when no longer required. Ensure prompt removal when line no longer required, and inform The Clatterbridge Cancer Centre s IV CNS of removal. References 1. Department of Health (DOH) (2001) Guidelines for preventing infection associated with the insertion and maintenance of central venous catheters, Journal of Hospital Infection, 47 Supplement S47 S67 2. Department of Health (DOH 2003). Winning Ways: Working together to reduce health care associated infection in England 3. Department of Health (DOH 2005). Saving Lives: A delivery programme to reduce health care associated infection including MRSA 4. Goodwin M, Carlson I (1993) The peripherally inserted catheter: a retrospective look at 3 years of insertions, Journal of Intravenous Nursing, 16 (2) 92-103 5. Hadaway L (1998) Catheter connection, Journal of Vascular access devices 3 (3), 40. 6. INS (2000) Infusion Nursing Standards of Practice, Journal of Intravenous Nursing 23 (6S) supplement 7. Todd J (1998) Peripherally inserted central catheters. Professional Nurse 13(5) 297-302 8. Jones A (2004) Dressings for the Management of Catheter Sites A review. JAVA, Vol. 9 No 1, 1-8. 9. Campbell H, Carrington M (1999) Peripheral IV cannula dressings: advantages and disadvantages. British Journal of Nursing, 8(21):1420-1422, 1424-1427. Issue Date: 26 th July 2012 Page: Page 11 of 12 Filename: FNUAMANMI Issue No: 2.0

10. Treston-Aurand J et al (1997) Impact of dressing materials on central venous catheter infection rates. Journal of Intravenous Nursing 20(4):201-206. 11. Wille JC (1993) A comparison of two transparent film-type dressings in central venous therapy. Journal of Hospital Infection 23(2):113-121 Issue Date: 26 th July 2012 Page: Page 12 of 12 Filename: FNUAMANMI Issue No: 2.0