Butler Community College Health, Education, and Public Services Division Denise LaKous Revised Spring 2014 Implemented Fall 2015 Textbook Update Fall 2015 COURSE OUTLINE Pathophysiology Course Description BI 23. 4 hours credit. Prerequisite: BI 240 with a C or better. This course will enable the student to develop an understanding of the concepts of pathophysiology including inflammation and healing, immune responses, fluid/electrolyte imbalances, pain, neoplasms and genetics. The student will apply these underlying concepts to explore the pathophysiology, etiology, clinical manifestations and treatments of common disorders in major body systems. Required Materials Huether, S., Understanding pathophysiology. Elsevier Health Sciences. Supplemental Huether, S., Study guide for understanding pathophysiology. Elsevier Health Sciences. * - For complete textbook information, refer to https://bookstore.butlercc.edu Butler-assessed Outcomes The intention is for the student to be able to: 1. Apply concepts of inflammation and healing, immune responses, fluid/electrolyte imbalances, pain, neoplasms and genetics to common disorders in major body systems. 2. Discuss the pathophysiology, etiology, clinical manifestations and treatments of common disorders in the major body systems. 3. Apply pathophysiology content to health related practices. Learning PACT Skills that will be developed and documented in this course Through involvement in this course, the student will develop ability in the following PACT skill area(s): Analytical Thinking Skills Critical thinking - Through the analysis of case studies, the student will develop critical thinking skills related to the impact of pathophysiology on illness. Major Summative Assessment Task(s) These Butler-assessed Learning Outcomes and the Learning PACT skills will be demonstrated by: 1. Analyzing a progressive case study involving a common disorder of a major body system. BI 231 Pathophysiology 1
2. Presenting a teaching project involving one common disorder of a major body system. Skills or Competencies Actions that are essential to achieve the course outcomes: 1. Assess the etiology and pathophysiology of disease. 2. Troubleshoot problems and make decisions using diagnostic testing and clinical manifestations. 3. Communicate the etiology, pathophysiology, clinical manifestations, diagnostic testing, and medical treatments by presenting a student teaching assignment. 4. Discuss common etiology, pathophysiology, clinical manifestations, diagnostic testing, and medical treatments on the discussion board. 5. Identify and explain the differences between evidence based practice and tradition or opinion on the test material and discussion board assignments. 6. Use professional and authentic resources versus opinion resources on the student teaching assignment bibliography. 7. Relate the etiology, pathophysiology, clinical manifestations, diagnostic testing, and medical treatments within the test questions and case study project. Learning Units I. Inflammatory response A. Vascular response to injury B. Cellular and chemical response to injury C. Acute and chronic inflammation D. Manifestations of inflammation II. III. IV. Tissue repair and wound healing A. Tissue repair B. Factors influencing wound healing Immune System A. Normal immune response B. Four types of hypersensitivity C. Immunodeficiency D. Autoimmunity Neoplasms A. Benign and malignant neoplasms B. Incidence and risk factors of cancers C. Characteristics of normal and malignant cells D. Effects of cancer on the body E. Cancer treatment modalities V. Fluid, electrolyte and acid base imbalances A. Fluid compartment relationships B. Fluid volume excess and fluid volume deficit BI 231 Pathophysiology 2
C. Sodium, potassium and calcium imbalances D. Acid base imbalances VI. Genetic and congenital disorders A. Patterns of recessive and dominant Mendelian inheritance B. Congenital defects and genetic disorders C. Single gene inheritance, chromosomal disorders and multifactorial inheritance VII. Pain A. List the causes of pain B. Describe the pain pathways and theories of pain C. Identify the characteristics of pain D. Discuss treatments recommended for pain management VIII. Alterations in hematologic function A. Red blood cell disorders B. White blood cell disorders C. Lymphoid tissue disorders D. Coagulation and bleeding disorders IX. Alterations in cardiovascular function A. Peripheral arterial and venous disorders BI 231 Pathophysiology 3
B. Alterations in blood pressure C. Coronary vascular disorders D. Structural, infectious or inflammatory cardiac disorders E. Heart failure and shock X. Alterations in respiratory function A. Infectious disorders and neoplasms B. Obstructive lung disorders C. Pulmonary vascular disorders D. Pleural disorders BI 231 Pathophysiology 4
E. Chest trauma XI. Alterations in digestive function A. Oral and esophageal disorders B. Gastric disorders C. Small and large Intestinal disorders D. Hepatic and biliary disorders XII. Alterations in renal and urinary tract function A. Urinary infection and obstruction disorders B. Glomerular disorders BI 231 Pathophysiology 5
C. Renal failure XIII. Alterations in neurological function A. Alterations in cerebral homeostasis increased intracranial pressure B. Spinal cord injury C. Central nervous system disorders D. Degenerative and peripheral nervous system disorders XIV. Alterations in endocrine function A. Thyroid and parathyroid disorders B. Diabetes mellitus BI 231 Pathophysiology 6
C. Disorders of adrenal cortical XV. Alterations in musculoskeletal function A. Musculoskeletal injury and trauma B. Metabolic disorders C. Degenerative disorders D. Autoimmune and inflammatory disorders E. Infectious and neoplasm disorders XVI. Alterations in integumentary A. Skin disorders B. Skin cancers BI 231 Pathophysiology 7
XVII. Alterations in reproductive function A. Male reproductive organ disorders B. Female reproductive organ disorders C. Breast disorders Learning Activities Independent and collaborative learning activities will be assigned to assist the student to achieve the intended learning outcomes. Class discussion, lecture, group activities, reading assignments, and classroom and Internet activities will also contribute to the learning process. Grade Determination Grade determination will be based upon class participation, assignments, exams and the assessment tasks. The student must earn a 75% or C to be successful in the class. BI 231 Pathophysiology 8