Depression in Women Etiology & Management Strategies Diana E. Ramos, MD,MPH

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Depression in Women Etiology & Management Strategies Diana E. Ramos, MD,MPH Associate Clinical Professor, Keck University of Southern California Medical Director, Reproductive Health, Los Angeles County Public Health Departments

Nearly Twice as Many Women as Men Suffer from Clinical Depression Age-Specific Rates of Major Depression in the US Kessler, RC, Zhan S, et al

Depression Across the Female Life Birth Premenstrual Perimenopause Death Menarche Menopause Pregnancy/Postpartum Baby Blues Postpartum Psychosis Postpartum Depression

Women and Depression Depressive disorders afflict 2-3 times more females than males (Burt & Stein 2002) More frequent reports of bodily symptoms, such as fatigue, appetite and sleep problems. (Silverstein, 2002; Barsky et al, 2001) More likely than others to develop alcohol problems (no such link between alcohol and depression in men) (Caldwell et al 2002; Moscato et al 1997) 54% reported use of complementary and alternative medicine. African American women were less likely to use these than non-hispanic white women (Wu et al, 2007)

Women, Stress, and Depression Superwoman syndrome Taking care of everyone Taking on too many commitments Difficulty setting limits and saying no Feeling guilty when saying no Behavior culturally accepted, expected, encouraged, especially among women of color Set up for exhaustion and depressive symptoms

Major Racial Ethnic Groups in US 80 70 60 50 40 30 20 10 0 1 4 12 Race 14 74 AA/AN AA/PI AA Latino White By 2010 minority populations are projected to grow 60% U.S. Census 2000

Culture Influences Mental Illness & Mental Health Communication (verbal and non-verbal) Manifestation of symptoms Family and community support Health-seeking behaviors Support systems and protective factors How people perceive & cope with mental illness How doctors interact with people with mental illness Stigma and shame associated with mental illness Spirituality (predestination, views of illness, etc) (Surgeon General, 2001)

Conceptual Framework of Mental Well-being in Women of Color Race Gender Socioeconomic & Other Status Social Cultural & Psychological Factors Physical Health & Genetic Factors Health Behaviors & Health Care Mental Wellbeing Adapted from Brown & Keith, 2003

African American Community Tend to report poor social support after delivery and feelings of isolation Loss of historical traditions : doing the month (new mother is cared for by elders for roughly 30 days postpartum to allow for recuperation) Significant social stressors Often fearful of the system secondary go historical trauma passed down through generations Los Angeles Best Babies Network 4-08 Maternal Depression Conference

Latino Community Feelings of guilt or shame, concerns about being seen as crazy Immigration status may be put at risk if they seek treatment Language barrier Marital discord Reliance upon religion Apprehension about medical field and medication Put others before themselves Los Angeles Best Babies Network 4-08 Maternal Depression Conference

Caucasian Social stressors, generally not of the socioeconomic nature Greater access to support/services due to no language barrier Concern about stigma Expectations to be the perfect mom soccer mom

Immigrant Community Fearful of seeking services Unfamiliar with new culture and potential for rejection Stigma Fear of having their children taken away Language barrier Family shame History of trauma or PTSD Lack of social support

Depression Across the Female Life Birth Premenstrual Perimenopause Death Menarche Menopause Pregnancy/Postpartum Baby Blues Postpartum Psychosis Postpartum Depression

Adolescence In 2004, suicide was the third leading cause of death among youths and young adults aged 10--24 years in the US, accounting for 4,599 deaths Suicide increased significantly in girls aged 10-14 (up 76%) and in girls aged 15-19 (up 32%) (CDC 2007)

Risk Factors for Maternal Depression Prior depression (30%) Prior postpartum depression (50%) or psychosis (70%) Depression during pregnancy Prior PMDD Family history of depression or bipolar disorder Recent stressful events: marital/partner discord, loss of loved one, family Illness, premature birth

Baby Blues: 70% affected: cry, sad, irritability, irregular sleeping Peaks 3-5 days after delivery, emotional let down that does not impair function Postpartum Post Partum Depression: can last up to 1 yr Impair mother and delay child s cognitive and social development Postpartum Psychosis 1-2 /1000 births First weeks after delivery Delusions and hallucination - voices instructing them to harm/kill their baby A medical emergency requiring hospitalization

Consider Postpartum Depression if a Woman Experiences 5 Symptoms: Depressed mood Marked disinterest in activities Appetite or sleep disturbance Physical agitation Extreme fatigue Sense of worthlessness Decreased concentration Suicidal thoughts Effective treatment: psychotherapy/anti-depressive medication

Peri-menopause & Menopause Estrogen withdrawal Sleep deprivation from menopausal symptoms Life changes/stressors True depression

Depression Diagnosis and Treatment in Women Depression is misdiagnosed approximately 30 to 50% of the time Doctors are more likely to diagnose depression in women compared to men, even with similar scores on standardized measures of depression or when presenting with identical symptoms (WHO 2007) Antidepressant use among women is 2 times that of men (NCHS, CDC 2007) Use of antidepressants by women increased 3-fold between 1988-94 and 1999-2002 (NCHS, CDC 2007)

Disparities in Seeking Mental Health Care African Americans: more likely to use emergency services or primary care providers than mental health specialists. (Surgeon General, 2001) Asian Americans: Only 4% would seek help from mental health specialist vs. 26 percent of whites. (Zhang et al., 1998) Latinos: < 1 in 11 with mental disorders contact mental health specialists, & < 1 in 5 contact primary care providers. (Surgeon General, 2001) Native Americans: 44% with a mental health problem sought any kind of help--and only 28% of those contacted a mental health agency. (King, 1999)

Treatment for Depression Support Counseling Other treatments: light, alternative medicines Antidepressants Keep in mind patient s cultural background

Thank You!