Overcoming Barriers to Expanded Use of Non-Opioid Therapies to Manage Persistent Pain

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Overcoming Barriers to Expanded Use of Non-Opioid Therapies to Manage Persistent Pain CENTRAL OREGON AND GORGE SUMMIT TO REDUCE RX ABUSE CATRIONA BUIST, PSY.D. CLINICAL DIRECTOR OF PROGRESSIVE REHABILITATION ASSOCIATES PAIN PROGRAM CHAIR OF THE OREGON PAIN MANAGEMENT COMMISSION REDMOND, OR OCTOBER 14, 2015

Institute of Medicine Report 2011: A cultural transformation in pain prevention, care, education and research Chronic pain costs the nation up to $635 billion each year in medical treatment and lost productivity. The 2010 Patient Protection and Affordable Care Act required the Department of Health and Human Services (HHS) to enlist the IOM in examining pain as a public health problem. In this report, the IOM offers a blueprint for action in transforming prevention, care, education, and research, with the goal of providing relief for people with pain in America.

In 1998 Federation of State Medical Boards issued new guidelines saying opioids could be essential for tx of chronic pain VA 1999 and JCAHO 2000 pushed pain as the 5 th vital sign Regulators, doctors and patients misled into believing opioids safe and less addictive than other drugs Now an average of 46 Americans die every day from prescription opioid overdoses and heroin deaths have more than doubled to 8,000 a year since 2010 Recently JAMA found a 19% decline in opioid prescriptions

Opiates, Mental Health and Chronic Disability Interagency Guidelines on Prescribing Opioids for Pain 2015 Little evidence to support long term efficacy of chronic opioid analgesic therapy (COAT) in improving function and pain Opioids have a short term analgesic effect and pain relief of about 30% State of the Art Review: Opioids for Low Back Pain, Deyo, Von Korff, Duhrkoop. BMJ 2015; 350:g6380 Patients who use opioids for at least 90 days were greater than 60% more likely to be on chronic opioids in 5 years Overdose risk doubles at doses between 20-49 MED and increases 9x at doses of 100mg/day MED Adults with a history of depression, alcohol or other non-opioid substance use disorders are 3-5x more likely to receive COAT (Cicero, Wong, Tian, Lynskey, Todorov, Isenberg, 2009) Patients with substance use and /or psychiatric disorders are more likely to have complications from opioid use, misuse, abuse or overdose (Martin, Fan, Edlund, Devries, Braden, Sullivan, 2011)

New Draft Guidelines by the Centers for Disease Control and Prevention, September 2015 National prescribing guidelines being proposed Precaution when increase opiates to 50 MSEQ Avoid increasing dosage >90 MSEQ Prescribe up to 3 days of opioids for acute flare up Consider co-prescribing nalaxone with risk factors Avoid prescribing opiates and benzos concurrently

2 Excellent Resources in Oregon /The Oregon Pain Guidance Group http:// www.southernoregonopioidmanagem ent.org Central Oregon Pain Guide 2015 http://www.copainguide.org/ Oregon Pain Guidance (OPG) is a group of healthcare providers from Jackson and Josephine Counties in Southern Oregon, who are working together on standardizing community guidelines and best practices for treating patients with chronic pain. Central Oregon resource on complex chronic non-cancer pain guidance to support healthcare professionals, patients and families

Oregon campaign to reduce dependence on and deaths from prescrip3on opiates has many pieces Pa3ent Educa3on: Pa3ent beliefs and expecta3ons about LBP have a significant impact on outcomes Samantha Kaan samantha.kaan@multco.us (503) 349-5931 Safe disposal resources Treatment resources 7 Naloxone dispensing Public educa4on Mindfulness resources Pa4ent educa4on Pain educa4on resources Changes to prescrip4on prac4ces Provider educa4on

The Effect of Neuroscience Education on Pain, Disability, Anxiety, and Stress in Chronic Musculoskeletal Pain Adriaan Louw, PT, MAppSc, Ina Diener, PT, PhD, David S. Butler, PT, EdD, Emilio J. Puentedura, PT, DPT Arch Phys Med Rehabil Vol 92, December 2011 Conclusions: For chronic MSK pain disorders, there is compelling evidence that an educational strategy addressing neurophysiology and neurobiology of pain can have a positive effect on pain, disability, catastrophizing, and physical performance.

Pain = an unpleasant sensory and emotional experience associated with actual or potential tissue damage (International Association for the Study of Pain) Acute Phase (< 2 weeks) symptom relief, maintain activity, provide support high proportion return to activity and work Sub-acute (2-12 weeks) develop plan for RTW/activity, healthcare and workplace accommodation, identify psychosocial obstacles, cease ineffective healthcare optimal time to prevent the development of long term consequences including work loss Chronic (> 12 weeks) multidisciplinary approach, cognitive behavioral techniques, consider shifting goals, max RTW/activities requires more resources and more difficult to achieve.

www.tsoshop.co.uk/flags Initial (0-2 weeks) Early (2-12 weeks) Persistent (>12 weeks)

Red Flags Predicting Disability: A Biopsychosocial Approach 1. Catastrophizing 2. Fear of movement or re-injury 3. Expectations 4. Preoccupation with health 5. Worry and distress 6. Depression 7. Uncertainty 8. Extreme symptom report 9. Passive coping strategies 10. Serial ineffective therapy Tackling Musculoskeletal Problems: A Guide for Clinic and Workplace, 2009

Predictors of Persistent Disabling LBP Maladaptive pain coping behaviors Fear avoidance (avoiding movement, activities) Catastrophizing (excessive negative thoughts) Nonorganic signs (somatic focus) Functional impairment Low general health status Presence of psychiatric co-morbidities Chou, R., & Shekelle, P. Will This Patient Develop Persistent Disabling Low Back Pain? JAMA. April 7, 2010; Vol 303, No. 13, 1295-1302

Central Sensitization Centralization implies that peripheral nociceptive input might be responsible for some of a patient s pain but central nervous system factors likely amplify the pain. Volume control is set by levels of neurotransmitters. Central factors may result in fatigue, memory problems and sleep and mood disturbances probably because the same neurotransmitters that control pain and sensory sensitivity also control sleep, mood, memory and alertness (Phillips, Clauw. Arthritis Rheum. 2013;65(2):291-302). Clauw, D.J. JAMA, April 16, 2014, Vol 311, No 15

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PEG validated 3 item tool to assess pain intensity, interference with enjoyment of life and interference with general activity (Krebs, 2009) Interagency Guidelines on Prescribing Opioids for Pain 2015

Evidence Based Treatment for Chronic Pain Chronic pain self-management programs reduce the physical and psychosocial burden of chronic pain and reduce health care costs (Mann, Lefort, Vanderkerkhof, 2013) Evidence supports multimodal therapies to improve pain and function and reduce disability (Turk, 2002) (Gatchel, Okifuji, 2006) Multidisciplinary pain programs have strong clinical efficacy, cost-efficiency, and have been proven to improve function. Programs address the psychosocial and cognitive aspects along with physical rehabilitation. Interagency Guidelines on Prescribing Opioids for Pain 2015

Expected Outcomes for Integrated Pain Care INCREASE FUNCTION and activity level Reduce pain Simplify medication / reduce opioids Graded physical exercise Reduce emotional distress, such as depression and anxiety (CBT) Increase self-management / coping skills Increase quality of life Teach self-regulation of psychophysical arousal Decrease inappropriate health care utilization RTW or meaningful activity Pain Management Programs by the American Chronic Pain Association

Non-pharmacological Options for Pain Management Interagency Guidelines on Prescribing Opioids for Pain 2015 Adapted from Argoff, 2009 & Tauben, 2015 Cognitive Behavioral Approaches Physical Address distressing negative cognitions and beliefs, catastrophizing (pain coping characterized by excessively negative thoughts and statements about the future) Mindfulness, meditation, yoga, relaxation, biofeedback Activity coaching, graded exercise Spiritual Education (patient and caregivers) Identify existential distress, seek meaning and purpose in life Promote patient efforts aimed at increased functional capabilities

Self-Management Tools

Common Cognitive Distortions to Address in Therapy Catastrophizing Selective Abstraction (Black and White thinking) Should statements Overgeneralizing Cognitive Behavioral Therapy Magnifying the negative and anticipating the worst case scenario for events and experiences. If my pain continues like this I ll end up in a wheelchair. Attending to negative aspects of experiences and disqualifying the positive aspects. If I can t keep up with my friends when we shop, then there is not pain in going with them. Expectations (often unrealistic) about what one should or must be able to accomplish. I should be able to clean the house like I did before. Assuming that the outcome of one event inevitably applies to other or future events. My pain always ruins my plans. I ll never have a normal life again.

Acceptance & Commitment Therapy Goal of ACT is to help you live a rich, full, and meaningful life while effectively handling the pain that inevitably comes your way.

Mindfulness Mindfulness means paying attention in a particular way: on purpose, in the present moment, and nonjudgmentally. Jon Kabat-Zinn From Segal, Williams, and Teasdale (2002)

Hierarchy of Pain Treatment Developed by WHO (2006) finish start Nerve ablation Implanted pumps Spinal stimulation Surgery Behavioral treatments Nerve blocks and other injections Narcotics and other oral analgesics Muscle relaxants Physical and occupational therapy, Chiropractic, Acupuncture Non-steroidal anti-inflammatories Over-the-counter medications ABC s of Pain Relief and Treatment: Advances, Breakthroughs, and Choices. Dr. Tim Sams (2006)

* Starting January 1, 2016 the Oregon Health Plan will begin providing reimbursement for alternative pain care for LBP * http://www.oregon.gov/oha/herc/factsheet/back-policy-changes-fact-sheet.pdf - Comprehensive integrated tx focused on the biopsychosocial needs of patient - Added evidence based tx: Cognitive behavioral therapy, physical therapy, chiropractic manipulation, osteopathic manipulation, acupuncture, yoga - Restricts or eliminates ineffective or harmful tx: long term opioid prescribing, unnecessary intervention - Focus is to include medical, cognitive-behavioral, and psychoeducational interventions to increase function and quality of life - Programs should address: - Managing comorbid conditions (sleep, PTSD ) - Fear and exercise avoidance, catastrophizing - Teach self-management skills (gentle exercise, relaxation, mindfulness)

LBP Patients Will Be Triaged Based on Biopsychosocial Issues Using the STarT Back Screening Tool www.keele.ac.uk/sbst/downloadthetool/ or www.keele.ac.uk/sbst/onlinetool/ From the Bree Collaborative 2013

Comparison of stratified primary care management for low back pain with current best practice (STarT Back): a randomized controlled trial Lancet 2011: 378: 1560-71 Compared the clinical effectiveness and costeffectiveness of stratified primary care (intervention) with non-stratified current best practice (control) 851 patients were assigned to intervention (n=568) and control groups (n=283). Mean changes in the Roland Morris Disability Questionnaire were significantly higher in the intervention group at 4 months Stratified care was associated with a mean increase in generic health benefit and cost savings compared with the control group

The Oregon Pain Management Commission The mission of the Commission is to improve pain management in the State of Oregon through education, development of pain management recommendations, development of a multidiscipline pain management practice program for providers, research, policy analysis and model projects. - Goals for 2015: - Revise the 1 hour required pain management web-based module - Review pain education curriculum for schools - Provider survey to identify barriers to care for patients with pain - Plan pain awareness event or drug take back event - Review the delivery system models of care as relates to changes in healthcare and integration of pain tx into primary care

Upcoming PSO Meetings in Central Oregon The Pain Society of Oregon offers CME credits for activities that advance healthcare professionals understanding of and competency in treating pain Monthly meetings in Eugene, Portland, Central Oregon The Efficacy & Benefits of a Pilates-Based Approach in Physical Therapy For The Treatment of Low Back Pain October 22, 2015 Erin Novelli, MPT Pain Standards Task Force Community-Wide Initiatives for Safe Prescribing November 19, 2015 Kimberly Swanson, Ph.D

Worthwhile Resources for Providers and Patients YouTube Videos on pain: Understanding Pain: What to do about it in less than 5 Minutes Brainman Chooses Brainman Stops His Opioids Back Pain by Mike Evans TED talk by Lorimer Moseley Why Things Hurt Dan Clauw from UM Chronic Pain Is It All in Their Head (central sensitization) Smart phone apps: IREHAB Back Pain, My Pain Diary, or Pain Free Back for the iphone Exercise programs on YouTube from Bree Collaborative: Exercises for lower back http://www.youtube.com/watch?v=u_alxoz4774 Low back pain remedy stretching exercises http://www.youtube.com/watch?v=019f62bu364 Top 5 stretches to relieve low back pain http://www.youtube.com/watch?v=xnn3k2qj_lo Yoga for back pain http://www.youtube.com/watch?v=asthnvrxvae Pain Society of Oregon 541-345-7300 or 503-804-3072 www.painsociety.com Western Pain Society 541-345-7300 admin@painsociety.com www.ampainsoc.org/societies/wps/ American Pain Society http://www.ampainsoc.org/

Take Home Points Treatment and reimbursement for chronic pain is changing Screen for biopsychosocial issues Earlier intervention to other disciplines that provide evidence based/ outcomes oriented tx Know your community resources Catriona Buist, Psy.D. 503-292-0765 Cat@progrehab.com Www.progrehab.com