EDWARDS RESEARCH GRANTS AND SUPPORT Edwards served as the principal investigator or co-investigator on a number of National and International grants and commissions since 2009 with accumulated earning amount to over $9 million including competitive research grants, commissions and two ongoing project funds. Current Grants 2014-2018 National Institute of Health-NIH U01NS091951-133463 Tele-rehabilitation in the home versus therapy in-clinic for patients with stroke. 2015-2017 National Institute of Health-NIH R03HD084971 Transcranial direct current stimulation and robotic training in adults with cerebral palsy. Role: Co-Principal Investigator. Percent Effort: 40% Amount: US $194,025 2015-2018 Canadian Institutes of Health Research-MOP 286185 Non-invasive repeated therapeutic stimulation for aphasia recovery (NORTHSTAR). 2016-2017 New York State 1512080249 Improving hand function in chronic stroke with combined robotic training and transcranial direct current stimulation 2016-2018 Ekso Bionics, Inc. Walking improvement for SCI with exoskeleton (WISE Trial) 2017-2018 Nexstim Inc. rtms and intensive upper limb therapy in chronic stroke (E-Fit Trial) 2017-2018 MicroTransponder Inc. VNS and intensive upper limb therapy in chronic stroke
RESEARCH GRANT AND SUPPORT continued 2005-2007 Edith Cowan University Early Career Researcher Grant Is therapeutic brain stimulation during exercise therapy effective for enhancing functional agonist/antagonist muscle coordination in the treatment of spasticity? Percent Effort: 100% Amount: AU $14,941 2005 The Western Australian Institute for Medical Research & The Road Safety Council Neurotrauma Research Program Grant Can interventional brain stimulation improve motor performance after stroke? Amount: AU $106,000 2006-2007 Edith Cowan University Collaborative Research Investigation of I-Wave periodicity Transcranial Magnetic Stimulant applied during voluntary movement 2006-2007 Taisho Pharmaceutical Co. Ltd. (Japan) International Industry Grant Development of Methods to Assess Standing Fatigue Amount: US $106,569 2007-2010 The Western Australian Institute for Medical Research & The Road Safety Council Neurotrauma Research Program Grant Using brain stimulation to help recovery after spinal cord injury and stroke. Percent Effort: Consultant Amount: AU $201,000 2008 Burke Foundation Non-Invasive Brain stimulation and Human Motor Control Laboratory Start-up Percent Effort: 70% Amount: US $950,000 2009-2011 National Institute of Health-NIH R21 HD060999 Transcranial direct current stimulation and motor training in chronic stroke Amount: US $467,854
RESEARCH GRANT AND SUPPORT continued 2013-2014 Adelson Foundation Grant Physiological assays of learning and memory Role: Associate Investigator Amount: US $100,000 2013-2014 Pathmaker Neurosystems Inc. Spinal Direct Current Stimulation Amount: US $50,000 2013-2014 Skirball Foundation Virtual Reality in Upper Extremity Motor Rehabilitation Amount: US $50,000 2013-2015 National Institute of Health-NIH R21 HD077616 Non-invasive stimulation for improving motor function in spinal cord injury Amount: US $519,145 2013-2016 Nexstim Inc. rtms and intensive upper limb therapy in chronic stroke Amount: US $500,000 2014-2016 Train the Brain Foundation Robotics exoskeleton gait training in SCI and stroke Percent Effort: 20% Amount: US $600,000 2012-2017 National Institute of Health-NIH R01 HD069776 Transcranial Direct Current Stimulation and Robotic Training in Chronic Stroke Percent Effort: 40% Amount: US $3,181,223
RESEARCH GRANTS AND SUPPORT continued Other Funding; Cumulative Grants; and Non-Funded Scientific Pilot Projects Other Funding Since 2008 Edwards laboratory received US$1 million from: private donors, Burke Hospital, Cornell University donors, and the Cornell Clinical and Translational Science Center (CTSC). Since the recent launch of the RNC robotics fee-for-service program in April 2013, the Restorative Neurology Clinic (RNC) at Burke has generated more than US$1 million. Cumulative Research Grants and Commissions Non-Funded Scientific Pilot Projects Edwards is actively involved in nearly 30 scientific ongoing pilot projects. He is responsible for designing, implementing and coordinating these projects. 1. Effects of tdcs on motor unit recruitment in affected hand muscles of chronic stroke patients, Burke Medical Research Institute and Spaulding Rehabilitation Hospital Boston. 2. Effects of tdcs on trigeminal nerve reflexes, Burke Medical Research Institute in USA, and Hospital Clinic in Barcelona, Spain. 3. Effects of High-Definition tdcs on kinematic performance in chronic stroke, Burke Medical Research Institute and Harvard Medical School, Boston, USA. 4. Modulation of spinal excitability with repetitive, paired Transcranial Magnetic Stimulation (TMS) and peripheral nerve stimulation, BRC 391.
RESEARCH GRANTS AND SUPPORT continued Non-Funded Scientific Pilot Projects 5. Evaluation and tracking of the natural history of homonymous hemianopsia/quadrantanopsia after a first clinically evident stroke or a previous stroke without visual involvement: An Observational Study, BRC 404. 6. The effect of TDCS on motor unit recruitment in chronic stroke, BRC 440. 7. Physiological assay of drugs and rehabilitation to augment learning and memory, BRC 444. 8. Transcranial direct current stimulation and robotic training in adults with cerebral palsy, BRC 467. 9. Pilot testing of the leap motion as an effective tool for upper limb rehabilitation in stroke, BRC 477. 10. Robotic training in any neurological impairment that causes arm/hand deficits, BRC 481. 11. Lower limb robot training for any neurological deficit that leads to impaired gat or balance, BRC 482. 12. Neurophysiological evaluation and lower limb robot training for neurological disorders leading to impaired gait or balance, BRC 492. 13. Development of an EEG analysis tool to determine the effectiveness of a TDCS protocol, BRC 493. 14. Non-Invasive repeated therapeutic stimulation for aphasia recovery (NORTHSTAR), BRC 497. 15. Transcranial direct current stimulation as an adjuvant to intensive speech therapy for chronic post stroke aphasia, BRC 500. 16. RETT Syndrome: measuring mechanical stiffness and impedance, BRC 502. 17. Telerehabilitation in the home versus therapy in-clinic for patients with stroke: an assessor-blind, randomized, non-inferiority trial, BRC 503. 18. Transcranial direct current stimulation as adjunctive pharyngeal dysphagia treatment in an acute rehabilitation setting, BRC 519. 19. Immersive virtual reality for chronic neuropathic pain after spinal cord injury: a feasibility trial, BRC 527. 20. Robotic therapy by trained volunteers for upper limb motor recovery following stroke: a pilot project, BRC 529. 21. Walking Improvement for SCI with exoskeleton (WISE trial), BRC 530. 22. Walkbot robotic training for improvement in gait in sub-acute stroke, BRC 532. 23. Burke-Hocoma efficiency study, BRC 540. 24. Electrical field navigated 1 Hz RTMS for post-stroke motor recovery (E-FIT trial), BRC 542. 25. Maraviroc to augment rehabilitation outcomes after stroke (MAROS trial), BRC 544. 26. Parkinson s, Robotics, and RTMS, BRC 546.